Overview
SCIENTIFIC SCORE
Possibly Effective
Based on 6 Researches
7.8
USERS' SCORE
Moderately Good
Based on 11 Reviews
7.6
Supplement Facts
Serving Size: 1 Softgel
Amount Per Serving
%DV
Phosphatidylserine (PS) from Lecithin (Sunflower) (Helianthus annuus) Seed Oil
100 mg
†
Top Medical Research Studies
9
We explored how phosphatidylserine (PS) affects memory in patients and rats with Alzheimer's disease. The study involved 57 patients split into control and treatment groups, while AD rats were given various doses of PS for 12 weeks.
Results showed that patients and treated rats improved memory scores and brain health significantly. The higher dose of PS was particularly effective in enhancing memory and reducing harmful brain inflammation.
Overall, phosphatidylserine appears promising as a treatment to boost memory function in Alzheimer's patients.
Results showed that patients and treated rats improved memory scores and brain health significantly. The higher dose of PS was particularly effective in enhancing memory and reducing harmful brain inflammation.
Overall, phosphatidylserine appears promising as a treatment to boost memory function in Alzheimer's patients.
Read More
7
Potential dietary intervention for dementia
We investigated how dietary DHA-enriched phosphatidylserine (DHA-PS) might affect brain health in mice with dementia. Over a four-month study, we observed changes in lipid profiles after mice were fed high-fat and low-fat diets supplemented with DHA-PC and DHA-PS.
The results showed that the high-fat diet negatively impacted brain lipid levels. However, the supplementation effectively restored levels of important brain lipids in the dementia model. This suggests that DHA-PS could provide a promising dietary approach to support brain health.
The results showed that the high-fat diet negatively impacted brain lipid levels. However, the supplementation effectively restored levels of important brain lipids in the dementia model. This suggests that DHA-PS could provide a promising dietary approach to support brain health.
Read More
8
We studied how phosphatidylserine enriched with eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) impacts Alzheimer's disease, particularly regarding amyloid-β (Aβ). Our findings revealed that DHA-PS effectively lowered Aβ production more than EPA-PS. Both forms provided significant protection to neurons against Aβ-induced toxicity. Notably, EPA-PS enhanced Aβ clearance in certain cell types. These results suggest phosphatidylserine could offer dietary strategies for Alzheimer's prevention and underline the importance of EPA and DHA in functional food development.
Read More
Most Useful Reviews
9
Expert recommended
Experts recommend Phosphatidylserine for its potential to prevent Alzheimer’s. I have been taking it for nearly three months now.
Read More
8
Anxiety management
Phosphatidylserine is a quality brain supplement from Jarrow Formulas. It helps manage anxiety by regulating cortisol levels. For individuals with Parkinson's or Alzheimer's disease, it significantly improves cognitive impairment by transporting nutrients into cells and promoting glucose metabolism in the brain. The capsules are soft and medium-sized.
Read More
6
Effective for elderly
2 people found this helpful
I initially took this for memory loss, later discovering its benefits for dementia, so I’ve provided it to my parents, who have Alzheimer’s disease. They find it easy to take. I will monitor their improvement over the next six months!
Read More
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 6 Researches
7.8
- All Researches
9
We explored how phosphatidylserine (PS) affects memory in patients and rats with Alzheimer's disease. The study involved 57 patients split into control and treatment groups, while AD rats were given various doses of PS for 12 weeks.
Results showed that patients and treated rats improved memory scores and brain health significantly. The higher dose of PS was particularly effective in enhancing memory and reducing harmful brain inflammation.
Overall, phosphatidylserine appears promising as a treatment to boost memory function in Alzheimer's patients.
Results showed that patients and treated rats improved memory scores and brain health significantly. The higher dose of PS was particularly effective in enhancing memory and reducing harmful brain inflammation.
Overall, phosphatidylserine appears promising as a treatment to boost memory function in Alzheimer's patients.
Read More
8
We studied how phosphatidylserine enriched with eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) impacts Alzheimer's disease, particularly regarding amyloid-β (Aβ). Our findings revealed that DHA-PS effectively lowered Aβ production more than EPA-PS. Both forms provided significant protection to neurons against Aβ-induced toxicity. Notably, EPA-PS enhanced Aβ clearance in certain cell types. These results suggest phosphatidylserine could offer dietary strategies for Alzheimer's prevention and underline the importance of EPA and DHA in functional food development.
Read More
8
Nicotinamide nanoparticles improve cognition
We explored how nicotinamide, combined with phosphatidylserine in solid lipid nanoparticles, could improve cognitive function in a rat model of Alzheimer's disease. By using these specially engineered particles, we aimed to enhance the brain's ability to take in the medication more effectively than traditional methods.
The results were promising. The phosphatidylserine-functionalized nanoparticles significantly improved cognition and reduced harmful tau proteins. This innovative delivery method may offer a practical solution for helping those affected by early-stage Alzheimer's.
The results were promising. The phosphatidylserine-functionalized nanoparticles significantly improved cognition and reduced harmful tau proteins. This innovative delivery method may offer a practical solution for helping those affected by early-stage Alzheimer's.
Read More
8
We examined how phosphatidylserine and curcumin affect memory, particularly in relation to Alzheimer's disease. In our study with day-old chicks, we found that higher doses of phosphatidylserine (37.9 mmol/l) and curcumin (2.7 mmol/l) notably improved memory retention when scopolamine-induced amnesia was present.
While lower doses were ineffective, our findings suggest that these treatments could serve as potential nontraditional memory enhancers for Alzheimer's. However, further research is needed to fully understand their impact on human subjects.
While lower doses were ineffective, our findings suggest that these treatments could serve as potential nontraditional memory enhancers for Alzheimer's. However, further research is needed to fully understand their impact on human subjects.
Read More
7
We explored how unsaturated phosphatidylserine and other lipids influence amyloid β (Aβ) aggregation in Alzheimer's disease. Using advanced techniques, we discovered that these lipids significantly impeded the formation of harmful Aβ plaques and reduced their toxicity to cells.
This suggests that incorporating unsaturated phospholipids into our diets might help slow down the advancement of Alzheimer’s. The study opens up exciting possibilities for using these lipids in developing new therapies aimed at fighting this debilitating disease.
This suggests that incorporating unsaturated phospholipids into our diets might help slow down the advancement of Alzheimer’s. The study opens up exciting possibilities for using these lipids in developing new therapies aimed at fighting this debilitating disease.
Read More
User Reviews
USERS' SCORE
Moderately Good
Based on 11 Reviews
7.6
- All Reviews
- Positive Reviews
- Negative Reviews
9
Expert recommended
Experts recommend Phosphatidylserine for its potential to prevent Alzheimer’s. I have been taking it for nearly three months now.
Read More
8
Anxiety management
Phosphatidylserine is a quality brain supplement from Jarrow Formulas. It helps manage anxiety by regulating cortisol levels. For individuals with Parkinson's or Alzheimer's disease, it significantly improves cognitive impairment by transporting nutrients into cells and promoting glucose metabolism in the brain. The capsules are soft and medium-sized.
Read More
6
Effective for elderly
2 people found this helpful
I initially took this for memory loss, later discovering its benefits for dementia, so I’ve provided it to my parents, who have Alzheimer’s disease. They find it easy to take. I will monitor their improvement over the next six months!
Read More
8
Protection against dementia
This excellent product from Jarrow, in soft capsule form, is great for protecting against dementia and Alzheimer’s.
Read More
7.5
Memory support
My husband takes this because Alzheimer's runs in his family. It seems to help his memory.
Read More
Frequently Asked Questions
6
Effective for elderly
2 people found this helpful
I initially took this for memory loss, later discovering its benefits for dementia, so I’ve provided it to my parents, who have Alzheimer’s disease. They find it easy to take. I will monitor their improvement over the next six months!
4
Supports disease progression
8 people found this helpful
Living in Australia, I face challenges as my partner has Alzheimer's. Doctors often dismiss my concerns regarding new treatments from the U.S. My husband has been on Phosphatidylserine for over two years, combined with other medications. While I cannot say it's miraculous, I believe it halts the disease's progression. Friends without Alzheimer reported sharper cognition while using it. It’s a good product, and I won’t be removing it from my husband’s regimen.
9
Expert recommended
Experts recommend Phosphatidylserine for its potential to prevent Alzheimer’s. I have been taking it for nearly three months now.
8
Anxiety management
Phosphatidylserine is a quality brain supplement from Jarrow Formulas. It helps manage anxiety by regulating cortisol levels. For individuals with Parkinson's or Alzheimer's disease, it significantly improves cognitive impairment by transporting nutrients into cells and promoting glucose metabolism in the brain. The capsules are soft and medium-sized.
7.5
Memory support
My husband takes this because Alzheimer's runs in his family. It seems to help his memory.
7.5
Preventative measure
1 people found this helpful
I watched a video on elderly healthcare in Canada that introduced brain-nourishing supplements. This product caught my attention, and I’m using it as a preventive measure against Alzheimer's. I take one pill daily to boost memory.
8
We studied how phosphatidylserine enriched with eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) impacts Alzheimer's disease, particularly regarding amyloid-β (Aβ). Our findings revealed that DHA-PS effectively lowered Aβ production more than EPA-PS. Both forms provided significant protection to neurons against Aβ-induced toxicity. Notably, EPA-PS enhanced Aβ clearance in certain cell types. These results suggest phosphatidylserine could offer dietary strategies for Alzheimer's prevention and underline the importance of EPA and DHA in functional food development.
9
We explored how phosphatidylserine (PS) affects memory in patients and rats with Alzheimer's disease. The study involved 57 patients split into control and treatment groups, while AD rats were given various doses of PS for 12 weeks.
Results showed that patients and treated rats improved memory scores and brain health significantly. The higher dose of PS was particularly effective in enhancing memory and reducing harmful brain inflammation.
Overall, phosphatidylserine appears promising as a treatment to boost memory function in Alzheimer's patients.
Results showed that patients and treated rats improved memory scores and brain health significantly. The higher dose of PS was particularly effective in enhancing memory and reducing harmful brain inflammation.
Overall, phosphatidylserine appears promising as a treatment to boost memory function in Alzheimer's patients.
7
We explored how unsaturated phosphatidylserine and other lipids influence amyloid β (Aβ) aggregation in Alzheimer's disease. Using advanced techniques, we discovered that these lipids significantly impeded the formation of harmful Aβ plaques and reduced their toxicity to cells.
This suggests that incorporating unsaturated phospholipids into our diets might help slow down the advancement of Alzheimer’s. The study opens up exciting possibilities for using these lipids in developing new therapies aimed at fighting this debilitating disease.
This suggests that incorporating unsaturated phospholipids into our diets might help slow down the advancement of Alzheimer’s. The study opens up exciting possibilities for using these lipids in developing new therapies aimed at fighting this debilitating disease.
8
We examined how phosphatidylserine and curcumin affect memory, particularly in relation to Alzheimer's disease. In our study with day-old chicks, we found that higher doses of phosphatidylserine (37.9 mmol/l) and curcumin (2.7 mmol/l) notably improved memory retention when scopolamine-induced amnesia was present.
While lower doses were ineffective, our findings suggest that these treatments could serve as potential nontraditional memory enhancers for Alzheimer's. However, further research is needed to fully understand their impact on human subjects.
While lower doses were ineffective, our findings suggest that these treatments could serve as potential nontraditional memory enhancers for Alzheimer's. However, further research is needed to fully understand their impact on human subjects.
References
- Zhaliazka K, Kurouski D. Nano-infrared analysis of amyloid β fibrils formed in the presence of lipids with unsaturated fatty acids. Nanoscale. 2023;15:19650. doi:10.1039/d3nr05184f
- Xu ZJ, Li Q, Ding L, Shi HH, Xue CH, et al. A comparative study of the effects of phosphatidylserine rich in DHA and EPA on Aβ-induced Alzheimer's disease using cell models. Food Funct. 2021;12:4411. doi:10.1039/d1fo00286d
- Zhao YC, Zhou MM, Zhang LY, Cong PX, Xu J, et al. Recovery of brain DHA-containing phosphatidylserine and ethanolamine plasmalogen after dietary DHA-enriched phosphatidylcholine and phosphatidylserine in SAMP8 mice fed with high-fat diet. Lipids Health Dis. 2020;19:104. doi:10.1186/s12944-020-01253-3
- Vakilinezhad MA, Amini A, Akbari Javar H, Baha'addini Beigi Zarandi BF, Montaseri H, et al. Nicotinamide loaded functionalized solid lipid nanoparticles improves cognition in Alzheimer's disease animal model by reducing Tau hyperphosphorylation. Daru. 2018;26:165. doi:10.1007/s40199-018-0221-5
- Barber TA, Edris EM, Levinsky PJ, Williams JM, Brouwer AR, et al. Amelioration of scopolamine-induced amnesia by phosphatidylserine and curcumin in the day-old chick. Behav Pharmacol. 2016;27:536. doi:10.1097/FBP.0000000000000242
- Zhang YY, Yang LQ, Guo LM. Effect of phosphatidylserine on memory in patients and rats with Alzheimer's disease. Genet Mol Res. 2015;14:9325. doi:10.4238/2015.August.10.13
