Overview

SCIENTIFIC SCORE
Possibly Effective
Based on 5 Researches
7
USERS' SCORE
Moderately Good
Based on 15 Reviews
7.8
Supplement Facts
Serving Size:  1 Softgel
Amount Per Serving
%DV
Calories
15
 
Total Fat
1.5 g
2%‡
Evening Primrose Seed Oil (Oenothera biennis)
1,300 mg
GLA (Gamma-Linolenic Acid)
130 mg

Top Medical Research Studies

7
EPO shows symptom relief potential
This study explored whether evening primrose oil (EPO) could replace non-steroidal anti-inflammatory drugs (NSAIDs) for people with rheumatoid arthritis (RA).

Over 12 months, we noticed that patients taking EPO showed notable subjective improvements and were able to reduce their NSAID intake.

However, a follow-up after three months of placebo indicated that while they felt better initially, their symptoms returned.

Importantly, EPO didn't change underlying disease progression, meaning it may not be a cure but can support symptom relief.
Read More
8
EPO shows promise for arthritis
We explored the effects of evening primrose oil (EPO) on rheumatoid arthritis, a condition marked by inflammation and dangerous new blood vessel formation. In our study, we used male albino rats with induced arthritis to see how EPO, alone or combined with common medications like aspirin and celecoxib, could help.

The results were promising, showing that EPO could normalize body weight and reduce harmful levels of specific inflammatory markers. Moreover, it helped decrease inflammation and improve overall joint health. Although combining EPO with other treatments enhanced its effects, we observed that EPO alone provides significant benefits in managing arthritis symptoms.
Read More
We evaluated the potential benefits of evening primrose oil in treating rheumatoid arthritis (RA) through a systematic review that included 22 studies. Results suggest that oils high in gamma linolenic acid (like evening primrose oil) may help reduce pain and improve disability in RA patients.

However, while some data supports these benefits, side effects were noted, and the effectiveness wasn’t consistent across all studies. Overall, there’s moderate evidence supporting evening primrose oil’s role in managing RA symptoms, but more rigorous research is needed to strengthen these findings.
Read More

Most Useful Reviews

9
Reduced stiffness
18 people found this helpful
Works for arthritis. This product works for my RA. I take one at night and one in the morning, alleviating stiffness in my fingers. When I stopped for three days, my arthritis flared up again. Other brands haven’t worked and sometimes caused nightmares, so I returned to this one. It works for me.
Read More
9
Manages arthritis symptoms
5 people found this helpful
Primula oil regulates hormones and helps with various ailments, including arthritis and menstrual disorders. It has a positive effect on high blood pressure and is effective against eczema and diabetes. I took it to restore my cycle and was pleased with the results. My skin did become quite oily, so I will try another course in winter.
Read More
7.5
Helps with arthritis
180 people found this helpful
The oil contains gamma-linolenic acid, which assists with arthritis and conditions linked to PMS and menopause. I purchased it for my sister pre-birth, and she had a smooth delivery. I use it to ease painful periods. Another mother found it beneficial during menopause. This truly is a miraculous remedy.
Read More

Medical Researches

SCIENTIFIC SCORE
Possibly Effective
Based on 5 Researches
7
  • All Researches
We examined the impact of evening primrose oil combined with fish oil on patients with rheumatoid arthritis through a 12-week study involving 60 participants. The results showed that both fish oil and the combination with evening primrose oil led to significant improvements in symptoms, like reduced disease activity scores and fewer tender joints.

However, while evening primrose oil contributed positively, the study emphasized the notable benefits of omega-3 fatty acids alone as well. Overall, this suggests a potential pathway for improving arthritis symptoms through these supplements.
Read More
8
EPO shows promise for arthritis
We explored the effects of evening primrose oil (EPO) on rheumatoid arthritis, a condition marked by inflammation and dangerous new blood vessel formation. In our study, we used male albino rats with induced arthritis to see how EPO, alone or combined with common medications like aspirin and celecoxib, could help.

The results were promising, showing that EPO could normalize body weight and reduce harmful levels of specific inflammatory markers. Moreover, it helped decrease inflammation and improve overall joint health. Although combining EPO with other treatments enhanced its effects, we observed that EPO alone provides significant benefits in managing arthritis symptoms.
Read More
We evaluated the potential benefits of evening primrose oil in treating rheumatoid arthritis (RA) through a systematic review that included 22 studies. Results suggest that oils high in gamma linolenic acid (like evening primrose oil) may help reduce pain and improve disability in RA patients.

However, while some data supports these benefits, side effects were noted, and the effectiveness wasn’t consistent across all studies. Overall, there’s moderate evidence supporting evening primrose oil’s role in managing RA symptoms, but more rigorous research is needed to strengthen these findings.
Read More
7
EPO shows symptom relief potential
This study explored whether evening primrose oil (EPO) could replace non-steroidal anti-inflammatory drugs (NSAIDs) for people with rheumatoid arthritis (RA).

Over 12 months, we noticed that patients taking EPO showed notable subjective improvements and were able to reduce their NSAID intake.

However, a follow-up after three months of placebo indicated that while they felt better initially, their symptoms returned.

Importantly, EPO didn't change underlying disease progression, meaning it may not be a cure but can support symptom relief.
Read More
4
Mild benefits of evening primrose oil
We conducted a six-month double-blind study exploring the effects of evening primrose oil on rheumatoid arthritis.

In total, 40 patients participated, with half receiving evening primrose oil and the other half a placebo.

While we noted a slight improvement in morning stiffness at three months with evening primrose oil, olive oil showed more significant reductions in pain and overall joint issues at the six-month mark.

This suggests that evening primrose oil provides only mild benefits, while olive oil may have important, previously overlooked advantages.
Read More

User Reviews

USERS' SCORE
Moderately Good
Based on 15 Reviews
7.8
  • All Reviews
  • Positive Reviews
  • Negative Reviews
9
Reduced stiffness
18 people found this helpful
Works for arthritis. This product works for my RA. I take one at night and one in the morning, alleviating stiffness in my fingers. When I stopped for three days, my arthritis flared up again. Other brands haven’t worked and sometimes caused nightmares, so I returned to this one. It works for me.
Read More
9
Manages arthritis symptoms
5 people found this helpful
Primula oil regulates hormones and helps with various ailments, including arthritis and menstrual disorders. It has a positive effect on high blood pressure and is effective against eczema and diabetes. I took it to restore my cycle and was pleased with the results. My skin did become quite oily, so I will try another course in winter.
Read More
7.5
Helps with arthritis
180 people found this helpful
The oil contains gamma-linolenic acid, which assists with arthritis and conditions linked to PMS and menopause. I purchased it for my sister pre-birth, and she had a smooth delivery. I use it to ease painful periods. Another mother found it beneficial during menopause. This truly is a miraculous remedy.
Read More
6
Eases arthritis pain
9 people found this helpful
The capsules are large but contain golden oil. Thankfully, there was no belching as often occurs with Omega-3. I experienced relief from PMS symptoms, particularly regarding my arthritis, resulting in reduced swelling and abdominal discomfort. Excellent composition without unnecessary additives. If you found my review helpful, please mark it as useful!
Read More
7.5
Anti-inflammatory for arthritis
3 people found this helpful
Fantastic! Evening primrose oil, derived from a North American plant, contains omega-6 fatty acids and gamma-linolenic acid, noted for its anti-inflammatory effects. It's utilised for various conditions including PMS, menopause, arthritis, and acne.
Read More

Frequently Asked Questions

6
Eases arthritis pain
9 people found this helpful
The capsules are large but contain golden oil. Thankfully, there was no belching as often occurs with Omega-3. I experienced relief from PMS symptoms, particularly regarding my arthritis, resulting in reduced swelling and abdominal discomfort. Excellent composition without unnecessary additives. If you found my review helpful, please mark it as useful!
7.5
Helps manage arthritis
This oil remarkably reduces PMS and menopause-related pain, combats chronic skin conditions like eczema, and offers anti-inflammatory benefits for arthritis. It's a valuable addition for hormone regulation and overall health, suitable for all ages.
7.5
Pain relief noted
3 people found this helpful
Rheumatism seems to respond well to pain relief, and I find that taking it alongside omega-3 helps with my arthritis.
6
Effective for arthritis
3 people found this helpful
Gamma-linolenic acid possesses anti-inflammatory properties, aiding conditions like arthritis and eczema.
7.5
Helps with arthritis
180 people found this helpful
The oil contains gamma-linolenic acid, which assists with arthritis and conditions linked to PMS and menopause. I purchased it for my sister pre-birth, and she had a smooth delivery. I use it to ease painful periods. Another mother found it beneficial during menopause. This truly is a miraculous remedy.
7.5
Aids arthritis recovery
Evening primrose oil actively regulates hormones and aids in various conditions, including arthritis, menstrual irregularities, and eczema. It's effective in restoring hormonal balance and is beneficial for mental well-being. I was anxious about using it, but it improved my cycle significantly. The only downside was oily skin.
We evaluated the potential benefits of evening primrose oil in treating rheumatoid arthritis (RA) through a systematic review that included 22 studies. Results suggest that oils high in gamma linolenic acid (like evening primrose oil) may help reduce pain and improve disability in RA patients.

However, while some data supports these benefits, side effects were noted, and the effectiveness wasn’t consistent across all studies. Overall, there’s moderate evidence supporting evening primrose oil’s role in managing RA symptoms, but more rigorous research is needed to strengthen these findings.
We examined the impact of evening primrose oil combined with fish oil on patients with rheumatoid arthritis through a 12-week study involving 60 participants. The results showed that both fish oil and the combination with evening primrose oil led to significant improvements in symptoms, like reduced disease activity scores and fewer tender joints.

However, while evening primrose oil contributed positively, the study emphasized the notable benefits of omega-3 fatty acids alone as well. Overall, this suggests a potential pathway for improving arthritis symptoms through these supplements.
4
Mild benefits of evening primrose oil
We conducted a six-month double-blind study exploring the effects of evening primrose oil on rheumatoid arthritis.

In total, 40 patients participated, with half receiving evening primrose oil and the other half a placebo.

While we noted a slight improvement in morning stiffness at three months with evening primrose oil, olive oil showed more significant reductions in pain and overall joint issues at the six-month mark.

This suggests that evening primrose oil provides only mild benefits, while olive oil may have important, previously overlooked advantages.
7
EPO shows symptom relief potential
This study explored whether evening primrose oil (EPO) could replace non-steroidal anti-inflammatory drugs (NSAIDs) for people with rheumatoid arthritis (RA).

Over 12 months, we noticed that patients taking EPO showed notable subjective improvements and were able to reduce their NSAID intake.

However, a follow-up after three months of placebo indicated that while they felt better initially, their symptoms returned.

Importantly, EPO didn't change underlying disease progression, meaning it may not be a cure but can support symptom relief.

References

  1. Veselinovic M, Vasiljevic D, Vucic V, Arsic A, Petrovic S, et al. Clinical Benefits of n-3 PUFA and ɤ-Linolenic Acid in Patients with Rheumatoid Arthritis. Nutrients. 2017;9. doi:10.3390/nu9040325
  2. El-Sayed RM, Moustafa YM, El-Azab MF. Evening primrose oil and celecoxib inhibited pathological angiogenesis, inflammation, and oxidative stress in adjuvant-induced arthritis: novel role of angiopoietin-1. Inflammopharmacology. 2014;22:305. doi:10.1007/s10787-014-0200-5
  3. Cameron M, Gagnier JJ, Chrubasik S. Herbal therapy for treating rheumatoid arthritis. Cochrane Database Syst Rev. 2011. doi:10.1002/14651858.CD002948.pub2
  4. Brzeski M, Madhok R, Capell HA. Evening primrose oil in patients with rheumatoid arthritis and side-effects of non-steroidal anti-inflammatory drugs. Br J Rheumatol. 1991;30:370.
  5. Belch JJ, Ansell D, Madhok R, O'Dowd A, Sturrock RD. Effects of altering dietary essential fatty acids on requirements for non-steroidal anti-inflammatory drugs in patients with rheumatoid arthritis: a double blind placebo controlled study. Ann Rheum Dis. 1988;47:96.
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