We investigated whether quercetin, a natural plant compound, could help combat common cold caused by rhinovirus (RV). In our study, quercetin reduced RV replication and inflammation in airway cells both in laboratory settings and in mice. When given before or after infection, quercetin limited the virus's ability to replicate and decreased harmful immune responses.
While our findings are promising, indicating that quercetin acts at various points in the virus's lifecycle, we recognize the need for further research to solidify its effectiveness in treating or preventing common colds.
Read More
8
Quercetin shows promise against HRV2
Anti-human rhinovirus 2 activity and mode of action of quercetin-7-glucoside from Lagerstroemia speciosa.
We investigated how quercetin 7-glucoside (Q7G), sourced from Lagerstroemia speciosa, affects human rhinovirus 2 (HRV2), a leading cause of the common cold. Utilizing a method to reduce cytopathic effects, we found that Q7G significantly reduced HRV2 replication by blocking the virus's early infection stage.
Interestingly, compared to ribavirin, a known antiviral, Q7G showed stronger efficacy, suggesting its potential as a treatment for HRV2. While these results are promising, further research is needed to assess the practicality of using Q7G in common cold therapies.
Read More
8
Quercetin's antiviral potential confirmed
Quercetin-3-Methyl Ether Induces Early Apoptosis to Overcome HRV1B Immune Evasion, Suppress Viral Replication, and Mitigate Inflammatory Pathogenesis.
We explored the effects of quercetin-3-methyl ether, a natural flavonoid, on the common cold virus, specifically human rhinovirus 1B (HRV1B).
In our study, we found that this compound not only inhibited the virus's replication in human cells but also targeted the early stages of infection.
Additionally, quercetin enhanced early cell death to help combat the virus's immune evasion tactics.
While our findings highlight its potential as a new antiviral agent, further research is necessary to confirm its effectiveness in broader treatments.
Read More
Most Useful Reviews
9
Strong immunity
16 people found this helpful
Jarrow Formulas Quercetin has been a part of my daily routine for over four years, at 1000 mg. As a lupus patient with a weakened immune system, I rarely catch the common cold, which is significantly better than before. I attribute my improved health largely to quercetin.
Read More
9
Cold remedy
5 people found this helpful
Quercetin paired with vitamin C works well for me. I take a total of 1500 mg at the onset of a common cold, and it often eliminates it overnight.
We explored the role of flavonoid compounds, like quercetin, in reducing the frequency and severity of upper respiratory tract infections (URTIs) in healthy adults. An in-depth review of 14 studies showed that flavonoid supplementation notably reduced the incidence of URTIs by 33% and sick days by 40%.
However, we noted that changes in immune markers were minimal, indicating that while there are advantages in reducing infections, the immune response may not be significantly affected.
Read More
9
Quercetin reduces rhinovirus effects
Quercetin inhibits rhinovirus replication in vitro and in vivo.
We investigated whether quercetin, a natural plant compound, could help combat common cold caused by rhinovirus (RV). In our study, quercetin reduced RV replication and inflammation in airway cells both in laboratory settings and in mice. When given before or after infection, quercetin limited the virus's ability to replicate and decreased harmful immune responses.
While our findings are promising, indicating that quercetin acts at various points in the virus's lifecycle, we recognize the need for further research to solidify its effectiveness in treating or preventing common colds.
Read More
8
Quercetin's antiviral potential confirmed
Quercetin-3-Methyl Ether Induces Early Apoptosis to Overcome HRV1B Immune Evasion, Suppress Viral Replication, and Mitigate Inflammatory Pathogenesis.
We explored the effects of quercetin-3-methyl ether, a natural flavonoid, on the common cold virus, specifically human rhinovirus 1B (HRV1B).
In our study, we found that this compound not only inhibited the virus's replication in human cells but also targeted the early stages of infection.
Additionally, quercetin enhanced early cell death to help combat the virus's immune evasion tactics.
While our findings highlight its potential as a new antiviral agent, further research is necessary to confirm its effectiveness in broader treatments.
Read More
8
Quercetin shows promise against viruses
Effectiveness of supplementation with quercetin-type flavonols for treatment of viral lower respiratory tract infections: Systematic review and meta-analysis of preclinical studies.
We explored the effectiveness of quercetin-type flavonols in combating viral lower respiratory infections through a systematic review of 11 preclinical studies.
Our findings highlighted quercetin's impressive antiviral activity, showing lower mortality rates and reduced viral loads in infected animals.
Moreover, quercetin appeared to alleviate inflammation and mucus production, suggesting a multifaceted benefit for respiratory health. Overall, quercetin could be a promising option for those facing respiratory viral challenges.
Read More
8
Quercetin shows promise against HRV2
Anti-human rhinovirus 2 activity and mode of action of quercetin-7-glucoside from Lagerstroemia speciosa.
We investigated how quercetin 7-glucoside (Q7G), sourced from Lagerstroemia speciosa, affects human rhinovirus 2 (HRV2), a leading cause of the common cold. Utilizing a method to reduce cytopathic effects, we found that Q7G significantly reduced HRV2 replication by blocking the virus's early infection stage.
Interestingly, compared to ribavirin, a known antiviral, Q7G showed stronger efficacy, suggesting its potential as a treatment for HRV2. While these results are promising, further research is needed to assess the practicality of using Q7G in common cold therapies.
Jarrow Formulas Quercetin has been a part of my daily routine for over four years, at 1000 mg. As a lupus patient with a weakened immune system, I rarely catch the common cold, which is significantly better than before. I attribute my improved health largely to quercetin.
Read More
9
Cold remedy
5 people found this helpful
Quercetin paired with vitamin C works well for me. I take a total of 1500 mg at the onset of a common cold, and it often eliminates it overnight.
Read More
9
Cold effectiveness
3 people found this helpful
Excellent for treating colds.
Read More
9
Quick relief
1 people found this helpful
I was pleasantly surprised by quercetin. Following my nutritionist's advice, it swiftly alleviated my sore throat at the first sign of a common cold.
Read More
9
Cold prevention
1 people found this helpful
Recommended by a naturopath, I used quercetin when I felt a cold coming on. I took 1 tablet three times a day for the first three days and then once daily. My husband and I didn’t become ill, which is uncommon for us.
The common cold is a viral infection of the upper respiratory tract, primarily affecting the nose and throat. It's caused by a variety of viruses, with rhinoviruses being the most prevalent. Symptoms generally include a runny or stuffy nose, sore throat, cough, sneezing, mild headache, and sometimes a low-grade fever. While the common cold is often mild and resolves on its own within a week or two, it can still be bothersome and impact daily activities.
Transmission occurs through respiratory droplets when an infected person coughs or sneezes, or by touching surfaces contaminated with the virus. Preventative measures include frequent handwashing, using hand sanitizer, and avoiding close contact with infected individuals. Since there is currently no cure for the common cold, treatment focuses on symptom relief through over-the-counter medications, adequate rest, and hydration. While colds may be uncomfortable, they are generally not serious; however, seeking medical attention may be necessary if symptoms worsen or persist for an extended period.
Quercetin is a naturally occurring flavonoid that is found in a variety of fruits, vegetables, and grains. Known for its antioxidant properties, quercetin is believed to help combat oxidative stress in the body, which can contribute to various health issues. You can commonly find it in foods such as apples, onions, berries, and citrus fruits, as well as in leafy greens. This makes it a popular dietary supplement among health enthusiasts looking to enhance their overall wellness.
Beyond its antioxidant capacity, quercetin is also being researched for its potential anti-inflammatory effects and benefits for immune support. Some studies suggest that it may help reduce allergy symptoms and improve exercise performance by decreasing muscle fatigue. With its wide range of potential health benefits, quercetin is often marketed as a natural remedy for various ailments, although it’s essential to consult a healthcare professional before starting any new supplement regimen to ensure its safety and effectiveness for your specific needs.
Quercetin is a flavonoid found in many fruits, vegetables, and grains, and has been studied for its potential health benefits, including its effects on the immune system. Some research suggests that quercetin may help reduce the severity and duration of the common cold due to its antioxidant and anti-inflammatory properties. It is thought to stabilize mast cells, which can minimize the release of histamines that contribute to allergy symptoms and respiratory issues.
However, while there is some promise, the evidence supporting quercetin's effectiveness specifically for treating the common cold is not conclusive. Most studies have been small or preliminary, and more research is needed to determine how effective quercetin truly is in preventing or treating colds. For those interested in exploring quercetin as a supplement, it's advisable to consult a healthcare professional, especially if you have underlying health conditions or are taking medications. Ultimately, maintaining a balanced diet rich in fruits and vegetables, staying hydrated, and practicing good hygiene are still the most reliable methods for preventing and managing colds.
Based on user reviews, the timeline to see results from taking quercetin for common colds varies. Many users report experiencing relief almost immediately upon onset of symptoms. For instance, one user noted that combining quercetin with vitamin C often eliminates cold symptoms overnight Read Review. Another user mentioned that quercetin helped alleviate their sore throat swiftly at the first signs of a cold Read Review.
However, some users did not report significant changes in their illness duration or severity, indicating a less consistent experience with the supplement Read Review. Overall, many recommend taking it regularly, as some users felt it made a difference in their susceptibility to colds over time Read Review. Therefore, while immediate results are possible for some, results can also depend on your individual health and the timing of use.
Quercetin, a natural flavonoid found in various plants, shows promise as a potential supplement for combating the common cold. Research indicates that it may inhibit the replication of common cold viruses, specifically rhinovirus types, by targeting early stages of infection (e.g., [1] and [7]). Additionally, quercetin has been found to modulate the immune response, potentially reducing inflammation and improving respiratory health (e.g., [4] and [3]).
While several studies highlight its antiviral properties, the effectiveness of quercetin as a mainstream treatment for colds remains to be fully confirmed, necessitating further research in human populations. For example, a review of multiple studies suggested that flavonoid supplementation, including quercetin, could reduce the incidence of upper respiratory tract infections by about 33%, although it had minimal impact on immune markers (e.g., [5]). Overall, while early findings are promising, more rigorous clinical trials are needed to ascertain quercetin's role in preventing or treating the common cold definitively.
Based on user reviews, many individuals have reported noticeable improvements in their symptoms after incorporating quercetin into their health regimen. A significant number of users claim reduced frequency and severity of colds, with one lupus patient sharing that their immune health has improved remarkably over four years of daily use, stating they "rarely catch the common cold" now Read Review. Others have experienced rapid relief at the onset of cold symptoms, with multiple reports of quercetin alleviating sore throats and cold symptoms quickly, sometimes even overnight when combined with vitamin C Read ReviewRead Review.
Conversely, not every experience has been positive, with some users stating they noticed little to no impact on their illness duration or severity Read Review. However, many find that taking quercetin regularly not only aids in immune support but also appears to enhance their overall well-being, mentioning benefits like fewer allergy symptoms and improved respiratory health Read Review. It's important to note that while many users report favorable outcomes, individual results can vary significantly based on personal health conditions and consistent use.
Based on user reviews, there appears to be a favorable response to combining quercetin with other supplements, particularly vitamin C, for alleviating common cold symptoms. Many users noted that taking quercetin alongside vitamin C has yielded quick relief, with one user claiming that this combination often eliminates cold symptoms overnight Read Review. Additionally, another user mentioned increased intake of quercetin when feeling a cold approaching, stating that they take multiple capsules daily to enhance their immune response Read Review.
While some users experienced significant benefits from this supplement pairing, not all reviews reflect positive outcomes. A few individuals did not notice any change in the duration or severity of their cold symptoms despite regular use of quercetin during their illness Read Review. However, many users emphasize that quercetin, especially when used in concert with other dietary supplements, can uplift overall immune health and reduce susceptibility to colds over time Read Review. Users consistently highlight the importance of individual health conditions and consistent use in determining the effectiveness of this supplement.
Based on user reviews, the recommended doses of quercetin for alleviating common cold symptoms vary widely, reflecting individual experiences and preferred strategies. Some users advocate for higher doses, such as 1500 mg at the onset of a cold, claiming it can sometimes eliminate symptoms overnight Read Review. Others report taking 1000 mg daily as part of their routine, crediting quercetin with fewer illness occurrences Read Review. Additionally, taking one tablet three times a day for the first few days was effective for another user, who avoided illness altogether Read Review.
Conversely, some users opted for a more modest intake. For instance, taking one pill in the morning and another at night has been reported to significantly aid recovery from cold symptoms Read Review. Additionally, others mentioned they take quercetin as a daily supplement to bolster their immune response, with doses ranging from four to eight capsules depending on allergy or illness sensitivity Read Review. Overall, it seems that users find a personalized approach to dosing that suits their individual health needs and responses best.
9
Cold remedy
5 people found this helpful
Quercetin paired with vitamin C works well for me. I take a total of 1500 mg at the onset of a common cold, and it often eliminates it overnight.
9
Quick relief
1 people found this helpful
I was pleasantly surprised by quercetin. Following my nutritionist's advice, it swiftly alleviated my sore throat at the first sign of a common cold.
2
No effect noted
1 people found this helpful
I initially bought quercetin for its antibacterial properties to inhibit disease-causing bacteria. Despite taking it during colds, I didn't notice any effects or a reduction in my illness duration. I likely won't repurchase it.
9
Reduced cold incidence
Quercetin has supported my respiratory immunity throughout the epidemic. I take it two or three times a week, more frequently when the situation worsens. I find it helps me to be less susceptible to the common cold.
9
Strong immunity
16 people found this helpful
Jarrow Formulas Quercetin has been a part of my daily routine for over four years, at 1000 mg. As a lupus patient with a weakened immune system, I rarely catch the common cold, which is significantly better than before. I attribute my improved health largely to quercetin.
7.5
Allergy relief
Quercetin aided me with my spring allergies and colds, while also strengthening my immune system.
7.5
Allergy relief
14 people found this helpful
This is a fantastic product! My alternative medicine doctor recommended quercetin alongside my allergy medication. I typically take 4-8 capsules daily. If I anticipate consuming something I'm sensitive to, I take 4 capsules before the meal. It helps minimise reactions. If I feel a common cold coming on, I increase my intake.
9
Cold prevention
1 people found this helpful
Recommended by a naturopath, I used quercetin when I felt a cold coming on. I took 1 tablet three times a day for the first three days and then once daily. My husband and I didn’t become ill, which is uncommon for us.
7.5
Faster recovery
1 people found this helpful
I've been using this for three years whenever I catch a cold with a sore throat. I take one pill in the morning and one at night, which aids my recovery significantly.
8
Quercetin's antiviral potential confirmed
Quercetin-3-Methyl Ether Induces Early Apoptosis to Overcome HRV1B Immune Evasion, Suppress Viral Replication, and Mitigate Inflammatory Pathogenesis.
We investigated whether quercetin, a natural plant compound, could help combat common cold caused by rhinovirus (RV). In our study, quercetin reduced RV replication and inflammation in airway cells both in laboratory settings and in mice. When given before or after infection, quercetin limited the virus's ability to replicate and decreased harmful immune responses.
While our findings are promising, indicating that quercetin acts at various points in the virus's lifecycle, we recognize the need for further research to solidify its effectiveness in treating or preventing common colds.
7
Quercetin normalizes immune responses
Rhinovirus-Induced SIRT-1 via TLR2 Regulates Subsequent Type I and Type III IFN Responses in Airway Epithelial Cells.
We investigated how quercetin affects the immune response to rhinovirus, which can cause the common cold. Our findings revealed that TLR2 plays a crucial role in regulating the body's initial immune response. In patients with chronic obstructive pulmonary disease (COPD), the TLR2 pathway functions differently, resulting in excessive inflammatory responses.
Notably, when we treated COPD airway cells with quercetin, we noticed a normalization of the immune response. This suggests that quercetin may help calm the immune system's overreaction to cold viruses by enhancing SIRT-1 expression. Overall, quercetin shows promise in regulating immune responses, especially in affected COPD cells.
8
Quercetin shows promise against viruses
Effectiveness of supplementation with quercetin-type flavonols for treatment of viral lower respiratory tract infections: Systematic review and meta-analysis of preclinical studies.
We explored the effectiveness of quercetin-type flavonols in combating viral lower respiratory infections through a systematic review of 11 preclinical studies.
Our findings highlighted quercetin's impressive antiviral activity, showing lower mortality rates and reduced viral loads in infected animals.
Moreover, quercetin appeared to alleviate inflammation and mucus production, suggesting a multifaceted benefit for respiratory health. Overall, quercetin could be a promising option for those facing respiratory viral challenges.
9
Flavonoids reduce cold incidence
Effect of Flavonoids on Upper Respiratory Tract Infections and Immune Function: A Systematic Review and Meta-Analysis.
We explored the role of flavonoid compounds, like quercetin, in reducing the frequency and severity of upper respiratory tract infections (URTIs) in healthy adults. An in-depth review of 14 studies showed that flavonoid supplementation notably reduced the incidence of URTIs by 33% and sick days by 40%.
However, we noted that changes in immune markers were minimal, indicating that while there are advantages in reducing infections, the immune response may not be significantly affected.
References
Song JH, Mun SH, Mishra S, Kim SR, Yang H, et al. Quercetin-3-Methyl Ether Induces Early Apoptosis to Overcome HRV1B Immune Evasion, Suppress Viral Replication, and Mitigate Inflammatory Pathogenesis. Biomol Ther (Seoul). 2025;33:388. doi:10.4062/biomolther.2024.204
Cho H, Kim S, Lee SH, Park Y. Effect of onion ( L.) peel extract on natural killer cell and cytokines in a randomized, double-blind, placebo-controlled trial. Nutr Res Pract. 2024;18:33. doi:10.4162/nrp.2024.18.1.33
Brito JCM, Lima WG, Cordeiro LPB, da Cruz Nizer WS. Effectiveness of supplementation with quercetin-type flavonols for treatment of viral lower respiratory tract infections: Systematic review and meta-analysis of preclinical studies. Phytother Res. 2021;35:4930. doi:10.1002/ptr.7122
Xander N, Reddy Vari H, Eskandar R, Li W, Bolla S, et al. Rhinovirus-Induced SIRT-1 via TLR2 Regulates Subsequent Type I and Type III IFN Responses in Airway Epithelial Cells. J Immunol. 2019;203:2508. doi:10.4049/jimmunol.1900165
Somerville VS, Braakhuis AJ, Hopkins WG. Effect of Flavonoids on Upper Respiratory Tract Infections and Immune Function: A Systematic Review and Meta-Analysis. Adv Nutr. 2016;7:488. doi:10.3945/an.115.010538
Song JH, Park KS, Kwon DH, Choi HJ. Anti-human rhinovirus 2 activity and mode of action of quercetin-7-glucoside from Lagerstroemia speciosa. J Med Food. 2013;16:274. doi:10.1089/jmf.2012.2290
Ganesan S, Faris AN, Comstock AT, Wang Q, Nanua S, et al. Quercetin inhibits rhinovirus replication in vitro and in vivo. Antiviral Res. 2012;94:258. doi:10.1016/j.antiviral.2012.03.005