Overview
SCIENTIFIC SCORE
Possibly Effective
Based on 15 Researches
7.8
USERS' SCORE
Good
Based on 13 Reviews
8.3
Supplement Facts
Serving Size: 1 Capsule
Amount Per Serving
%DV
Quercetin
500 mg
†
Top Medical Research Studies
9
We recently tested a quercetin-based supplement, Cysta-Q, on 22 patients with interstitial cystitis (IC) in an open-label trial. Over 4 weeks, participants took two capsules daily, and we assessed their symptoms before and after treatment.
The results were encouraging; all patients reported improvements in their problem and symptom indices, as well as pain levels. Interestingly, everyone but one individual experienced some positive change, and there were no side effects reported.
These promising findings suggest that quercetin could be beneficial for those suffering from IC, although larger, controlled studies are needed for confirmation.
The results were encouraging; all patients reported improvements in their problem and symptom indices, as well as pain levels. Interestingly, everyone but one individual experienced some positive change, and there were no side effects reported.
These promising findings suggest that quercetin could be beneficial for those suffering from IC, although larger, controlled studies are needed for confirmation.
8
We sought to understand how quercetin could alleviate chronic pelvic pain associated with Chronic Prostatitis/Chronic Pelvic Pain Syndrome (CP/CPPS) using a rat model. Over four weeks, rats received oral quercetin while measuring various blood and prostate health markers.
Our findings revealed that quercetin improved prostate health by reducing inflammation and enhancing antioxidant capacity. Specifically, it lowered levels of harmful inflammatory markers and suppressed certain signaling pathways known to contribute to pain. Overall, quercetin showed significant protective effects against CP/CPPS.
Our findings revealed that quercetin improved prostate health by reducing inflammation and enhancing antioxidant capacity. Specifically, it lowered levels of harmful inflammatory markers and suppressed certain signaling pathways known to contribute to pain. Overall, quercetin showed significant protective effects against CP/CPPS.
7
We investigated how quercetin, a potential treatment for endometriosis-related pelvic pain, affects endometrial stromal cells. By using cells derived from menstrual effluent of both unaffected individuals and those with endometriosis, we observed quercetin's role in promoting decidualization, which is vital for embryo implantation.
Although the study shows promising mechanisms behind quercetin's effects, the direct benefits on reducing pelvic pain require further clinical exploration. Our findings suggest that while quercetin improves cellular responses, additional studies are needed to confirm its effectiveness as a treatment for chronic pelvic pain.
Although the study shows promising mechanisms behind quercetin's effects, the direct benefits on reducing pelvic pain require further clinical exploration. Our findings suggest that while quercetin improves cellular responses, additional studies are needed to confirm its effectiveness as a treatment for chronic pelvic pain.
Most Useful Reviews
9.5
Pain management improvement
This product has been wonderful for my Interstitial Cystitis. I cannot live without it; when I run out, my pain returns. This supplement effectively manages both pain and the frequency of urination. I take 1,000 mg daily and find it a great product!
5
Less foot pain
Quercetin alleviates foot pain and inflammation for me. As someone who is overweight, I struggle with pain in my soles and ankles, and this supplement helps. It’s said to protect Resveratrol from being metabolised by the liver, so I ensure a higher dosage. I remain cautious due to some studies suggesting possible side effects, yet I find it beneficial overall for my foot pain.
9.5
Joint pain relief
I highly recommend quercetin! It’s both an antioxidant and anti-inflammatory. I woke up with pain in my fingers each morning, but after about four weeks of using this product, my pain subsided notably. I can’t praise this product enough; it certainly worked for me!
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 15 Researches
7.8
- All Researches
9
Quercetin shows promise for endometriosis pain
We explored the effectiveness of a combination treatment involving quercetin, curcumin, and acetylcysteine for easing pelvic pain in women with endometriosis. In this study, 33 women took the supplement daily for two months while we monitored their pain levels related to dysmenorrhea, pelvic pain, and dyspareunia.
The results were promising, showing a significant reduction in pain symptoms and decreased reliance on NSAIDs. We observed that this treatment may serve as a helpful addition to managing endometriosis-related pain without notable side effects.
The results were promising, showing a significant reduction in pain symptoms and decreased reliance on NSAIDs. We observed that this treatment may serve as a helpful addition to managing endometriosis-related pain without notable side effects.
9
Quercetin alleviates pelvic pain
We explored the effects of Phyllanthus niruri extract and its isolated components, including quercetin, on hemorrhagic cystitis induced by cyclophosphamide in mice. The study involved treatment before and after inducing the condition and assessed pain, swelling, and bleeding.
We found that quercetin led to significant pain relief, while other compounds like gallic acid and rutin showed notable anti-inflammatory effects. Overall, the extract and its components proved beneficial in alleviating the treatment's side effects, suggesting potential therapeutic value.
We found that quercetin led to significant pain relief, while other compounds like gallic acid and rutin showed notable anti-inflammatory effects. Overall, the extract and its components proved beneficial in alleviating the treatment's side effects, suggesting potential therapeutic value.
9
We examined the effects of multimodal therapy on chronic pelvic pain using the UPOINT system. After 27 weeks, 100 patients receiving tailored treatments, including quercetin for organ-specific symptoms, showed notable improvement.
About 84% experienced significant symptom reduction, highlighting a median drop in pain scores from 11.5 to 6.1. While quercetin appeared beneficial, there was no guarantee that the number of symptoms predicted the outcome. Overall, this approach signifies a step forward in managing chronic pelvic pain effectively.
About 84% experienced significant symptom reduction, highlighting a median drop in pain scores from 11.5 to 6.1. While quercetin appeared beneficial, there was no guarantee that the number of symptoms predicted the outcome. Overall, this approach signifies a step forward in managing chronic pelvic pain effectively.
9
We recently tested a quercetin-based supplement, Cysta-Q, on 22 patients with interstitial cystitis (IC) in an open-label trial. Over 4 weeks, participants took two capsules daily, and we assessed their symptoms before and after treatment.
The results were encouraging; all patients reported improvements in their problem and symptom indices, as well as pain levels. Interestingly, everyone but one individual experienced some positive change, and there were no side effects reported.
These promising findings suggest that quercetin could be beneficial for those suffering from IC, although larger, controlled studies are needed for confirmation.
The results were encouraging; all patients reported improvements in their problem and symptom indices, as well as pain levels. Interestingly, everyone but one individual experienced some positive change, and there were no side effects reported.
These promising findings suggest that quercetin could be beneficial for those suffering from IC, although larger, controlled studies are needed for confirmation.
9
We examined the potential of quercetin, a bioflavonoid, in alleviating pelvic pain in men with chronic prostatitis syndromes. In a randomized, double-blind trial involving 30 men, those taking quercetin experienced a notable reduction in symptoms compared to those on a placebo.
Specifically, 67% of men on quercetin showed a 25% improvement in symptoms, compared to just 20% in the placebo group. Even more encouraging, a follow-up with additional participants using a quercetin combination showed an impressive 82% improvement. Overall, quercetin is well tolerated and may significantly help for many facing chronic pelvic pain.
Specifically, 67% of men on quercetin showed a 25% improvement in symptoms, compared to just 20% in the placebo group. Even more encouraging, a follow-up with additional participants using a quercetin combination showed an impressive 82% improvement. Overall, quercetin is well tolerated and may significantly help for many facing chronic pelvic pain.
User Reviews
USERS' SCORE
Good
Based on 13 Reviews
8.3
- All Reviews
- Positive Reviews
- Negative Reviews
9.5
Pain management improvement
This product has been wonderful for my Interstitial Cystitis. I cannot live without it; when I run out, my pain returns. This supplement effectively manages both pain and the frequency of urination. I take 1,000 mg daily and find it a great product!
5
Less foot pain
Quercetin alleviates foot pain and inflammation for me. As someone who is overweight, I struggle with pain in my soles and ankles, and this supplement helps. It’s said to protect Resveratrol from being metabolised by the liver, so I ensure a higher dosage. I remain cautious due to some studies suggesting possible side effects, yet I find it beneficial overall for my foot pain.
9.5
Joint pain relief
I highly recommend quercetin! It’s both an antioxidant and anti-inflammatory. I woke up with pain in my fingers each morning, but after about four weeks of using this product, my pain subsided notably. I can’t praise this product enough; it certainly worked for me!
9.5
Significant pain relief
The pain feels much improved after taking it.
9.5
Menstrual pain relief
The 30-pound small bottle is very handy and greatly effective in alleviating menstrual pain. 👍
Frequently Asked Questions
9.5
Joint pain relief
I highly recommend quercetin! It’s both an antioxidant and anti-inflammatory. I woke up with pain in my fingers each morning, but after about four weeks of using this product, my pain subsided notably. I can’t praise this product enough; it certainly worked for me!
8.3
Joint pain noticeably reduced
I found quercetin quite effective for my joint pain. After trying it for three months, my joint pain significantly decreased, and after half a year, I feel as though my joints are almost cured. I continue taking it for ongoing health care.
8.8
Better sleep quality
After a few days of taking this, I noticed a marked improvement in my sleep and a reduction in arthritic pain. I’m eager to see the long-term results as I continue taking quercetin, which was delivered quickly in secure packaging.
9.5
Pain management improvement
This product has been wonderful for my Interstitial Cystitis. I cannot live without it; when I run out, my pain returns. This supplement effectively manages both pain and the frequency of urination. I take 1,000 mg daily and find it a great product!
5.5
Effective pain reliever
Quercetin is a great substitute for Ibuprofen; for effective pain relief, I need to take between one and two grams. A 1000 mg size would be ideal. Additionally, it serves well as an antioxidant.
8.8
Intestinal pain relief
I found it helpful. After taking this, the intestinal pain disappeared. It likely healed some minor injuries.
8.8
Frequency of pain reduced
I took this drug alongside vitamin C for its flavonoids to boost the antiviral and immunomodulatory effects of both. After some time, I noticed a significant reduction in the frequency of my pain!
8
Eased joint pain
I use quercetin together with Curcumin to alleviate the inflammation and joint pain associated with my arthritis. This combination allows me to function more normally throughout my day-to-day life.
9
Quercetin shows promise for endometriosis pain
We explored the effectiveness of a combination treatment involving quercetin, curcumin, and acetylcysteine for easing pelvic pain in women with endometriosis. In this study, 33 women took the supplement daily for two months while we monitored their pain levels related to dysmenorrhea, pelvic pain, and dyspareunia.
The results were promising, showing a significant reduction in pain symptoms and decreased reliance on NSAIDs. We observed that this treatment may serve as a helpful addition to managing endometriosis-related pain without notable side effects.
The results were promising, showing a significant reduction in pain symptoms and decreased reliance on NSAIDs. We observed that this treatment may serve as a helpful addition to managing endometriosis-related pain without notable side effects.
9
We examined the potential of quercetin, a bioflavonoid, in alleviating pelvic pain in men with chronic prostatitis syndromes. In a randomized, double-blind trial involving 30 men, those taking quercetin experienced a notable reduction in symptoms compared to those on a placebo.
Specifically, 67% of men on quercetin showed a 25% improvement in symptoms, compared to just 20% in the placebo group. Even more encouraging, a follow-up with additional participants using a quercetin combination showed an impressive 82% improvement. Overall, quercetin is well tolerated and may significantly help for many facing chronic pelvic pain.
Specifically, 67% of men on quercetin showed a 25% improvement in symptoms, compared to just 20% in the placebo group. Even more encouraging, a follow-up with additional participants using a quercetin combination showed an impressive 82% improvement. Overall, quercetin is well tolerated and may significantly help for many facing chronic pelvic pain.
4
We investigated whether genetic variations could influence treatment success for chronic pelvic pain syndrome. Our research involved analyzing the DNA of 36 men with this condition and comparing their genetic markers to 252 control participants.
We found that those with a specific low IL-10 producing genotype were more common among patients experiencing chronic pelvic pain. Specifically, quercetin, an anti-inflammatory treatment, was less effective in patients with low TNF-alpha genotypes. This suggests the importance of genetic factors in determining how well quercetin works for relieving pelvic pain.
We found that those with a specific low IL-10 producing genotype were more common among patients experiencing chronic pelvic pain. Specifically, quercetin, an anti-inflammatory treatment, was less effective in patients with low TNF-alpha genotypes. This suggests the importance of genetic factors in determining how well quercetin works for relieving pelvic pain.
7
UPOINT therapy shows symptom improvement
We explored the effectiveness of UPOINT-guided multimodal therapy in managing chronic prostatitis and chronic pelvic pain syndrome. Our study involved 110 men aged 26 to 68, where we compared an intervention group receiving a tailored treatment, including 1g of Quercetin, to a control group with no therapy.
After treatment, we observed notable improvements in symptom scores and overall quality of life for the intervention group. This suggests that multimodal therapy, which includes Quercetin, could be beneficial for men suffering from this painful condition.
After treatment, we observed notable improvements in symptom scores and overall quality of life for the intervention group. This suggests that multimodal therapy, which includes Quercetin, could be beneficial for men suffering from this painful condition.
References
- Delenko J, Xue X, Chatterjee PK, Hyman N, Shih AJ, et al. Quercetin enhances decidualization through AKT-ERK-p53 signaling and supports a role for senescence in endometriosis. Reprod Biol Endocrinol. 2024;22:100. doi:10.1186/s12958-024-01265-z
- Liu H, Wang Z, Xie Q, Chi A, Li Y, et al. Ningmitai capsules have anti-inflammatory and pain-relieving effects in the chronic prostatitis/chronic pelvic pain syndrome mouse model through systemic immunity. Front Pharmacol. 2022;13:949316. doi:10.3389/fphar.2022.949316
- Fadin M, Nicoletti MC, Pellizzato M, Accardi M, Baietti MG, et al. Effectiveness of the integration of quercetin, turmeric, and N-acetylcysteine in reducing inflammation and pain associated with endometriosis. In-vitro and in-vivo studies. Minerva Ginecol. 2020;72:285. doi:10.23736/S0026-4784.20.04615-8
- Krakhotkin DV, Chernylovskyi VA, Bakurov EE, Sperl J. Evaluation of influence of the UPOINT-guided multimodal therapy in men with chronic prostatitis/chronic pelvic pain syndrome on dynamic values NIH-CPSI: a prospective, controlled, comparative study. Ther Adv Urol. 2019;11:1756287219857271. doi:10.1177/1756287219857271
- Maurizi A, De Luca F, Zanghi A, Manzi E, Leonardo C, et al. The role of nutraceutical medications in men with non bacterial chronic prostatitis and chronic pelvic pain syndrome: A prospective non blinded study utilizing flower pollen extracts versus bioflavonoids. Arch Ital Urol Androl. 2019;90:260. doi:10.4081/aiua.2018.4.260
- Park S, Lim W, Bazer FW, Whang KY, Song G. Quercetin inhibits proliferation of endometriosis regulating cyclin D1 and its target microRNAs in vitro and in vivo. J Nutr Biochem. 2019;63:87. doi:10.1016/j.jnutbio.2018.09.024
- Meng LQ, Yang FY, Wang MS, Shi BK, Chen DX, et al. Quercetin protects against chronic prostatitis in rat model through NF-κB and MAPK signaling pathways. Prostate. 2018;78:790. doi:10.1002/pros.23536
- Schiavi MC, Porpora MG, Vena F, Prata G, Sciuga V, et al. Orally Administered Combination of Hyaluronic Acid, Chondroitin Sulfate, Curcumin, and Quercetin in the Prevention of Postcoital Recurrent Urinary Tract Infections: Analysis of 98 Women in Reproductive Age After 6 Months of Treatment. Female Pelvic Med Reconstr Surg. 2019;25:309. doi:10.1097/SPV.0000000000000560
- Güney G, Kaya C, Oto G, Yıldırım S, Özdemir H, et al. Effects of quercetin and surgicel for preventing adhesions after gynecological surgery: A rat uterine horn model. J Obstet Gynaecol Res. 2017;43:179. doi:10.1111/jog.13185
- Boeira VT, Leite CE, Santos AA, Edelweiss MI, Calixto JB, et al. Effects of the hydroalcoholic extract of Phyllanthus niruri and its isolated compounds on cyclophosphamide-induced hemorrhagic cystitis in mouse. Naunyn Schmiedebergs Arch Pharmacol. 2011;384:265. doi:10.1007/s00210-011-0668-0
- Shoskes DA, Nickel JC, Kattan MW. Phenotypically directed multimodal therapy for chronic prostatitis/chronic pelvic pain syndrome: a prospective study using UPOINT. Urology. 2010;75:1249. doi:10.1016/j.urology.2010.01.021
- Shoskes DA, Hakim L, Ghoniem G, Jackson CL. Long-term results of multimodal therapy for chronic prostatitis/chronic pelvic pain syndrome. J Urol. 2003;169:1406.
- Shoskes DA, Albakri Q, Thomas K, Cook D. Cytokine polymorphisms in men with chronic prostatitis/chronic pelvic pain syndrome: association with diagnosis and treatment response. J Urol. 2002;168:331.
- Katske F, Shoskes DA, Sender M, Poliakin R, Gagliano K, et al. Treatment of interstitial cystitis with a quercetin supplement. Tech Urol. 2001;7:44.
- Shoskes DA, Zeitlin SI, Shahed A, Rajfer J. Quercetin in men with category III chronic prostatitis: a preliminary prospective, double-blind, placebo-controlled trial. Urology. 1999;54:960.
