Overview
SCIENTIFIC SCORE
Possibly Effective
Based on 15 Researches
7.1
USERS' SCORE
Excellent
Based on 16 Reviews
9.1
Supplement Facts
Serving Size: 1 Capsule
Amount Per Serving
%DV
Saccharomyces boulardii(an S. cerevisiae Strain)
250 mg(5 Billion CFU)
†
MOS Yeast Fraction(Min. 35% Manno-oligosaccharides [MOS]) (S. cerevisiae)
200 mg
†
Top Medical Research Studies
7
We investigated whether Saccharomyces boulardii could alleviate nausea and other discomforts during a 14-day treatment for Helicobacter pylori. In our study with 124 patients, half received S. boulardii while the other half received a placebo.
Participants reported improvements in gastrointestinal symptoms, such as diarrhea and epigastric discomfort. However, while S. boulardii helped with treatment tolerability and post-treatment nausea, it did not significantly enhance the overall success rate of eradicating H. pylori.
Participants reported improvements in gastrointestinal symptoms, such as diarrhea and epigastric discomfort. However, while S. boulardii helped with treatment tolerability and post-treatment nausea, it did not significantly enhance the overall success rate of eradicating H. pylori.
8
Saccharomyces boulardii reduces nausea effectively
We explored how Saccharomyces boulardii supplementation, when added to standard triple therapy (STT), can impact children’s nausea during H. pylori treatment. Analyzing data from 15 randomized controlled trials with over 2,000 participants, we found that S. boulardii significantly reduced nausea rates compared to STT alone—down to 12.7% from 21.3%.
Besides nausea, there were also lower occurrences of other gastrointestinal side effects. This suggests that S. boulardii not only aids in treating the infection but also makes the treatment process easier for kids.
Besides nausea, there were also lower occurrences of other gastrointestinal side effects. This suggests that S. boulardii not only aids in treating the infection but also makes the treatment process easier for kids.
We conducted a double-blind, placebo-controlled study to see how Saccharomyces boulardii might help in reducing nausea during Helicobacter pylori eradication therapy.
Our findings suggest that those taking S. boulardii experienced significantly fewer gastrointestinal symptoms, including nausea, when compared to the control group.
While S. boulardii showed promise in alleviating some treatment-related side effects, Lactobacillus reuteri did not have notable effects. Further research with larger sample sizes is recommended to deepen our understanding.
Our findings suggest that those taking S. boulardii experienced significantly fewer gastrointestinal symptoms, including nausea, when compared to the control group.
While S. boulardii showed promise in alleviating some treatment-related side effects, Lactobacillus reuteri did not have notable effects. Further research with larger sample sizes is recommended to deepen our understanding.
Most Useful Reviews
10
Nausea resolved
The probiotic worked wonders for my husband's gastrointestinal issues. After persistent nausea and other stomach problems post-medication, we tried this. Within a month, all symptoms were completely alleviated. I'm delighted with the natural composition, devoid of unnecessary chemicals.
10
Nausea management
A must-have for dealing with diarrhoea, nausea, and stomachaches—just take one and forget the unpleasant moments.
10
Nausea controlled
I adore saccharomycetes because they combat intestinal issues without affecting good bacteria. They’re non-colonising and are eliminated after treatment. I took them on an empty stomach, and they significantly alleviated symptoms of nausea and reduced discomfort for my IBS.
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 15 Researches
7.1
- All Researches
8
We examined how adding Saccharomyces boulardii to conventional treatments could aid in eradicating certain gastric infections. Through a thorough search of databases over the past two decades, we focused on outcomes, including nausea and other side effects.
Our findings suggest that incorporating Saccharomyces boulardii significantly enhances eradication rates while also decreasing nausea and other gastrointestinal issues. This gives us hope for better treatment options in battling these prevalent gastric conditions.
Our findings suggest that incorporating Saccharomyces boulardii significantly enhances eradication rates while also decreasing nausea and other gastrointestinal issues. This gives us hope for better treatment options in battling these prevalent gastric conditions.
8
Saccharomyces boulardii reduces nausea effectively
We explored how Saccharomyces boulardii supplementation, when added to standard triple therapy (STT), can impact children’s nausea during H. pylori treatment. Analyzing data from 15 randomized controlled trials with over 2,000 participants, we found that S. boulardii significantly reduced nausea rates compared to STT alone—down to 12.7% from 21.3%.
Besides nausea, there were also lower occurrences of other gastrointestinal side effects. This suggests that S. boulardii not only aids in treating the infection but also makes the treatment process easier for kids.
Besides nausea, there were also lower occurrences of other gastrointestinal side effects. This suggests that S. boulardii not only aids in treating the infection but also makes the treatment process easier for kids.
We conducted a double-blind, placebo-controlled study to see how Saccharomyces boulardii might help in reducing nausea during Helicobacter pylori eradication therapy.
Our findings suggest that those taking S. boulardii experienced significantly fewer gastrointestinal symptoms, including nausea, when compared to the control group.
While S. boulardii showed promise in alleviating some treatment-related side effects, Lactobacillus reuteri did not have notable effects. Further research with larger sample sizes is recommended to deepen our understanding.
Our findings suggest that those taking S. boulardii experienced significantly fewer gastrointestinal symptoms, including nausea, when compared to the control group.
While S. boulardii showed promise in alleviating some treatment-related side effects, Lactobacillus reuteri did not have notable effects. Further research with larger sample sizes is recommended to deepen our understanding.
8
Probiotics prevent diarrhea in children
We examined the use of probiotics—specifically Saccharomyces boulardii—as a remedy for preventing antibiotic-associated diarrhea (AAD) in children. Our analysis included 23 studies with nearly 4,000 participants, and we found that probiotics significantly reduced AAD incidence from 19% in control groups to 8% in those receiving probiotics.
While this suggests that probiotics can be beneficial, the overall evidence quality was moderate. Importantly, no serious side effects were reported, making probiotics a safe option for many children, though caution is advised in those with pre-existing health conditions.
While this suggests that probiotics can be beneficial, the overall evidence quality was moderate. Importantly, no serious side effects were reported, making probiotics a safe option for many children, though caution is advised in those with pre-existing health conditions.
8
We aimed to find out if probiotics could help prevent antibiotic-associated diarrhea (AAD) in children. In our evaluation of 23 studies involving nearly 4,000 kids, we discovered that probiotics, especially Lactobacillus rhamnosus and Saccharomyces boulardii, significantly reduced the incidence of AAD compared to placebo or no treatment.
The results showed that only 8% of children taking probiotics experienced AAD, versus 19% in the control group. Importantly, no serious adverse events were linked to probiotic use, making it a safe option. However, we also emphasized the need for further research to explore other probiotic strains and ensure consistent results.
The results showed that only 8% of children taking probiotics experienced AAD, versus 19% in the control group. Importantly, no serious adverse events were linked to probiotic use, making it a safe option. However, we also emphasized the need for further research to explore other probiotic strains and ensure consistent results.
User Reviews
USERS' SCORE
Excellent
Based on 16 Reviews
9.1
- All Reviews
- Positive Reviews
- Negative Reviews
10
Nausea resolved
The probiotic worked wonders for my husband's gastrointestinal issues. After persistent nausea and other stomach problems post-medication, we tried this. Within a month, all symptoms were completely alleviated. I'm delighted with the natural composition, devoid of unnecessary chemicals.
10
Nausea management
A must-have for dealing with diarrhoea, nausea, and stomachaches—just take one and forget the unpleasant moments.
10
Nausea controlled
I adore saccharomycetes because they combat intestinal issues without affecting good bacteria. They’re non-colonising and are eliminated after treatment. I took them on an empty stomach, and they significantly alleviated symptoms of nausea and reduced discomfort for my IBS.
10
No nausea experienced
This supplement was recommended by an integrative physician. I waited a long time for it, but it was worth it. I give it to children during meals. I had no negative effects—no nausea, heartburn, or unpleasant aftertaste. It improves digestion and microflora, especially during antibiotic treatment, with no adverse reactions.
9.5
Nausea resolved
I keep a jar for emergencies, especially for intestinal concerns. They provided quick relief from pain and discomfort, even after a stressful episode. Within 40 minutes of taking the pill, my nausea subsided so I could fall asleep.
Frequently Asked Questions
10
Nausea resolved
The probiotic worked wonders for my husband's gastrointestinal issues. After persistent nausea and other stomach problems post-medication, we tried this. Within a month, all symptoms were completely alleviated. I'm delighted with the natural composition, devoid of unnecessary chemicals.
9.5
Nausea resolved
I keep a jar for emergencies, especially for intestinal concerns. They provided quick relief from pain and discomfort, even after a stressful episode. Within 40 minutes of taking the pill, my nausea subsided so I could fall asleep.
8.8
Nausea alleviated
After a severe illness, my mother's gastrointestinal problems led to constant nausea and diarrhoea. While it took time, saccharomycetes helped significantly. It’s been effective during my gastritis episodes, reducing nausea and improving overall gut health.
9.5
Eases nausea
A must-have! This product has significantly helped me with IBS, bloating, and nausea. It also aids in digesting sugars. I have been using it on and off for several years, and I recommend it especially if you have SIBO.
9.5
Nausea reduced
I took this along with a prebiotic for gastritis. Thankfully, it eliminated nausea and pain.
9.5
Nausea diminished
My integrative doctor recommended this supplement. I give it to my children during meals. There were no adverse effects, and it improved digestion whilst reducing bloating and nausea. It’s particularly effective during antibiotic treatment.
3
Nausea occurred
I wanted to try these probiotics after hearing many positive reviews. Unfortunately, I could not take more than five as I experienced nausea and felt as though my stomach was full for five days.
8
Saccharomyces boulardii reduces nausea effectively
We explored how Saccharomyces boulardii supplementation, when added to standard triple therapy (STT), can impact children’s nausea during H. pylori treatment. Analyzing data from 15 randomized controlled trials with over 2,000 participants, we found that S. boulardii significantly reduced nausea rates compared to STT alone—down to 12.7% from 21.3%.
Besides nausea, there were also lower occurrences of other gastrointestinal side effects. This suggests that S. boulardii not only aids in treating the infection but also makes the treatment process easier for kids.
Besides nausea, there were also lower occurrences of other gastrointestinal side effects. This suggests that S. boulardii not only aids in treating the infection but also makes the treatment process easier for kids.
We conducted a double-blind, placebo-controlled study to see how Saccharomyces boulardii might help in reducing nausea during Helicobacter pylori eradication therapy.
Our findings suggest that those taking S. boulardii experienced significantly fewer gastrointestinal symptoms, including nausea, when compared to the control group.
While S. boulardii showed promise in alleviating some treatment-related side effects, Lactobacillus reuteri did not have notable effects. Further research with larger sample sizes is recommended to deepen our understanding.
Our findings suggest that those taking S. boulardii experienced significantly fewer gastrointestinal symptoms, including nausea, when compared to the control group.
While S. boulardii showed promise in alleviating some treatment-related side effects, Lactobacillus reuteri did not have notable effects. Further research with larger sample sizes is recommended to deepen our understanding.
7
Probiotic eases nausea without improving eradication
We explored the effect of adding the probiotic Saccharomyces boulardii to standard therapy for H. pylori infection in a randomized controlled trial involving 160 adults.
While the probiotic didn’t significantly improve H. pylori eradication rates, we observed that patients who received it reported fewer side effects like nausea and abdominal discomfort during treatment.
This suggests that Saccharomyces boulardii could help manage adverse effects associated with antibiotic therapy.
While the probiotic didn’t significantly improve H. pylori eradication rates, we observed that patients who received it reported fewer side effects like nausea and abdominal discomfort during treatment.
This suggests that Saccharomyces boulardii could help manage adverse effects associated with antibiotic therapy.
7
We investigated whether Saccharomyces boulardii could alleviate nausea and other discomforts during a 14-day treatment for Helicobacter pylori. In our study with 124 patients, half received S. boulardii while the other half received a placebo.
Participants reported improvements in gastrointestinal symptoms, such as diarrhea and epigastric discomfort. However, while S. boulardii helped with treatment tolerability and post-treatment nausea, it did not significantly enhance the overall success rate of eradicating H. pylori.
Participants reported improvements in gastrointestinal symptoms, such as diarrhea and epigastric discomfort. However, while S. boulardii helped with treatment tolerability and post-treatment nausea, it did not significantly enhance the overall success rate of eradicating H. pylori.
8
We explored the effects of adding Saccharomyces boulardii to standard treatments for Helicobacter pylori infection. The study, involving 2,200 participants, found that while overall eradication rates remained below the desired levels, those taking S. boulardii had significantly better results.
Most importantly, this helpful yeast also reduced nausea and other side effects associated with the therapy. Its addition led to a notable decrease in instances of nausea, proving beneficial for patients undergoing H. pylori treatment.
Most importantly, this helpful yeast also reduced nausea and other side effects associated with the therapy. Its addition led to a notable decrease in instances of nausea, proving beneficial for patients undergoing H. pylori treatment.
References
- Li M, Xie Y. Efficacy and safety of as an adjuvant therapy for the eradication of : a meta-analysis. Front Cell Infect Microbiol. 2025;15:1441185. doi:10.3389/fcimb.2025.1441185
- Liu LH, Han B, Tao J, Zhang K, Wang XK, et al. The effect of Saccharomyces boulardii supplementation on Helicobacter pylori eradication in children: a systematic review and meta-analysis of Randomized controlled trials. BMC Infect Dis. 2023;23:878. doi:10.1186/s12879-023-08896-4
- Naghibzadeh N, Salmani F, Nomiri S, Tavakoli T. Investigating the effect of quadruple therapy with Saccharomyces boulardii or Lactobacillus reuteri strain (DSMZ 17648) supplements on eradication of Helicobacter pylori and treatments adverse effects: a double-blind placebo-controlled randomized clinical trial. BMC Gastroenterol. 2022;22:107. doi:10.1186/s12876-022-02187-z
- Sirchak YS, Patskun SV, Bedey NV. DYNAMICS OF GASTRIN LEVEL IN PATIENTS WITH DIABETES MELLITUS 2 TYPE AND CHRONIC GASTRITIS AFTER HELICOBACTER PYLORI ERADICATION THERAPY. Wiad Lek. 2020;73:2512.
- He CX, Kong FT, Liang F, Wang KX, Li H, et al. [Influence of different timing of combined with bismuth quadruple therapy for eradication]. Zhonghua Yi Xue Za Zhi. 2019;99:1731. doi:10.3760/cma.j.issn.0376-2491.2019.22.010
- Chotivitayatarakorn P, Mahachai V, Vilaichone RK. Effectiveness of 7-Day and 14-Day Moxifloxacin-Dexlansoprazole Based Triple Therapy and Probiotic Supplement for Helicobacter Pylori Eradication in Thai Patients with Non-Ulcer Dyspepsia: A Double-Blind Randomized Placebo-Controlled Study. Asian Pac J Cancer Prev. 2017;18:2839.
- Feng JR, Wang F, Qiu X, McFarland LV, Chen PF, et al. Efficacy and safety of probiotic-supplemented triple therapy for eradication of Helicobacter pylori in children: a systematic review and network meta-analysis. Eur J Clin Pharmacol. 2017;73:1199. doi:10.1007/s00228-017-2291-6
- Hayes SR, Vargas AJ. Probiotics for the Prevention of Pediatric Antibiotic-Associated Diarrhea. Explore (NY). 2016;12:463. doi:10.1016/j.explore.2016.08.015
- Goldenberg JZ, Lytvyn L, Steurich J, Parkin P, Mahant S, et al. Probiotics for the prevention of pediatric antibiotic-associated diarrhea. Cochrane Database Syst Rev. 2015. doi:10.1002/14651858.CD004827.pub4
- Szajewska H, Horvath A, Kołodziej M. Systematic review with meta-analysis: Saccharomyces boulardii supplementation and eradication of Helicobacter pylori infection. Aliment Pharmacol Ther. 2015;41:1237. doi:10.1111/apt.13214
- Zojaji H, Ghobakhlou M, Rajabalinia H, Ataei E, Jahani Sherafat S, et al. The efficacy and safety of adding the probiotic Saccharomyces boulardiito standard triple therapy for eradication of H.pylori: a randomized controlled trial. Gastroenterol Hepatol Bed Bench. 2013;6:S99.
- Dinleyici EC, Eren M, Dogan N, Reyhanioglu S, Yargic ZA, et al. Clinical efficacy of Saccharomyces boulardii or metronidazole in symptomatic children with Blastocystis hominis infection. Parasitol Res. 2011;108:541. doi:10.1007/s00436-010-2095-4
- Cindoruk M, Erkan G, Karakan T, Dursun A, Unal S. Efficacy and safety of Saccharomyces boulardii in the 14-day triple anti-Helicobacter pylori therapy: a prospective randomized placebo-controlled double-blind study. Helicobacter. 2007;12:309.
- Cremonini F, Di Caro S, Covino M, Armuzzi A, Gabrielli M, et al. Effect of different probiotic preparations on anti-helicobacter pylori therapy-related side effects: a parallel group, triple blind, placebo-controlled study. Am J Gastroenterol. 2002;97:2744.
- Polese B, Nicolai E, Genovese D, Verlezza V, La Sala CN, et al. Postprandial Gastrointestinal Function Differs after Acute Administration of Sourdough Compared with Brewer's Yeast Bakery Products in Healthy Adults. J Nutr. 2018;148:202. doi:10.1093/jn/nxx049
