5/29/2025
Last update
5/29/2025
Overview
SCIENTIFIC SCORE
Possibly Effective
Based on 7 Researches
7.9
USERS' SCORE
Good
Based on 1 Review
8.4
Supplement Facts
Serving Size: 1 Capsule
Amount Per Serving
%DV
Saccharomyces boulardii(an S. cerevisiae Strain)
250 mg(5 Billion CFU)
†
MOS Yeast Fraction(Min. 35% Manno-oligosaccharides [MOS]) (S. cerevisiae)
200 mg
†
Top Medical Research Studies
8
Potential cancer treatment from yeast
We investigated whether a special yeast cell wall treatment could inhibit the growth of MCF-7 breast cancer cells. Using hydrothermal methods, we created a soluble form of the yeast cell wall, known as YCW-H, and tested its effects. Remarkably, YCW-H reduced cell growth by nearly 59%, even when the cells were separated by a plastic barrier.
This suggests YCW-H releases factors that can combat cancer cell proliferation. The research shows that reactive carbon species, produced during the treatment, are linked to these effects, making YCW-H a promising option for future cancer therapies.
This suggests YCW-H releases factors that can combat cancer cell proliferation. The research shows that reactive carbon species, produced during the treatment, are linked to these effects, making YCW-H a promising option for future cancer therapies.
Read More
7
We explored how yeast-derived beta-(1,3)(1,6)-D-glucan impacts breast cancer cells and natural killer (NK) cells. Using both 2D and 3D cell culture models, we found that beta-glucan boosted NK cell proliferation and enhanced their ability to kill breast cancer cells, particularly in 2D models. However, while it did inhibit breast cancer cell growth in 2D significantly, the effect in 3D models was weak and not significant. Overall, beta-glucan shows potential in aiding immune response against breast cancer, though its effect varies by model.
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9.5
We explored a novel neoantigen vaccine system derived from Saccharomyces cerevisiae that effectively targets cancer cells, including breast cancer. In studies with mice, this vaccine not only stimulated a strong immune response but also significantly inhibited tumor growth in various models, including 4T1 breast cancer. When combined with specific immune enhancers, it led to complete tumor clearance and lasting immunity against tumors. These findings suggest a promising avenue for future cancer immunotherapy and personalized treatment options.
Read More
Most Useful Reviews
7.5
Life-saving defence
11 people found this helpful
Incredible for battling C-Diff! I suffered a severe case of undiagnosed C-Diff after multiple hospital visits. After diagnosis and antibiotics, I began taking these. Despite my initial doubts, it has prevented the return of C-Diff, which can be fatal. While ill, my breast cancer returned, yet I’m improving daily with ongoing treatment. Thank you, Jarrow Formulas, for saving my life.
Read More
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 7 Researches
7.9
- All Researches
9.5
We explored a novel neoantigen vaccine system derived from Saccharomyces cerevisiae that effectively targets cancer cells, including breast cancer. In studies with mice, this vaccine not only stimulated a strong immune response but also significantly inhibited tumor growth in various models, including 4T1 breast cancer. When combined with specific immune enhancers, it led to complete tumor clearance and lasting immunity against tumors. These findings suggest a promising avenue for future cancer immunotherapy and personalized treatment options.
Read More
8
Potential cancer treatment from yeast
We investigated whether a special yeast cell wall treatment could inhibit the growth of MCF-7 breast cancer cells. Using hydrothermal methods, we created a soluble form of the yeast cell wall, known as YCW-H, and tested its effects. Remarkably, YCW-H reduced cell growth by nearly 59%, even when the cells were separated by a plastic barrier.
This suggests YCW-H releases factors that can combat cancer cell proliferation. The research shows that reactive carbon species, produced during the treatment, are linked to these effects, making YCW-H a promising option for future cancer therapies.
This suggests YCW-H releases factors that can combat cancer cell proliferation. The research shows that reactive carbon species, produced during the treatment, are linked to these effects, making YCW-H a promising option for future cancer therapies.
Read More
8
We explored a new approach to delivering the breast cancer drug doxorubicin (DOX) using modified yeast particles to minimize its harmful effects. The yeast β-glucan particles were designed to release DOX in a controlled manner, particularly in acidic environments typical of tumors. Our results displayed strong anti-tumor effects against breast cancer cells while also showing reduced toxicity compared to standard DOX. This innovative system offers hope for safer and more effective treatments targeting breast cancer.
Read More
8
We explored the impact of saccharomyces cerevisiae, commonly known as baker's yeast, combined with gold nanoparticles in treating breast cancer. This groundbreaking approach aimed to determine whether this combination could effectively induce cell death in cancerous cells.
Our findings revealed that using gold nanospheres alongside heat-killed yeast not only decreased certain harmful proteins in the cells but also led to significant tumor reduction compared to using yeast alone.
This suggests that this method is a promising non-invasive and natural treatment option for breast cancer.
Our findings revealed that using gold nanospheres alongside heat-killed yeast not only decreased certain harmful proteins in the cells but also led to significant tumor reduction compared to using yeast alone.
This suggests that this method is a promising non-invasive and natural treatment option for breast cancer.
Read More
8
We aimed to discover how heat-killed preparations of Saccharomyces cerevisiae could help in breast cancer therapy using a mouse model. Forty-two female mice were divided into groups, with some receiving tumor cells and others treated with these heat-killed products.
After 35 days of observation, we found that those receiving Saccharomyces exhibited reduced tumor growth compared to controls. The study highlighted significant changes in immune response, indicating promise for Saccharomyces cerevisiae as an effective complementary treatment in this context.
After 35 days of observation, we found that those receiving Saccharomyces exhibited reduced tumor growth compared to controls. The study highlighted significant changes in immune response, indicating promise for Saccharomyces cerevisiae as an effective complementary treatment in this context.
Read More
User Reviews
USERS' SCORE
Good
Based on 1 Review
8.4
- All Reviews
- Positive Reviews
- Negative Reviews
7.5
Life-saving defence
11 people found this helpful
Incredible for battling C-Diff! I suffered a severe case of undiagnosed C-Diff after multiple hospital visits. After diagnosis and antibiotics, I began taking these. Despite my initial doubts, it has prevented the return of C-Diff, which can be fatal. While ill, my breast cancer returned, yet I’m improving daily with ongoing treatment. Thank you, Jarrow Formulas, for saving my life.
Read More
Frequently Asked Questions
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References
- Kitagawa T. Hydrothermal treatment of yeast cell wall generates potent anti-proliferative agents targeting MCF7 breast cancer cells effectively even under culture conditions separated by a plastic wall. PLoS One. 2025;20:e0313379. 10.1371/journal.pone.0313379
- Boulifa A, Raftery MJ, Franzén AS, Radecke C, Stintzing S, et al. Role of beta-(1→3)(1→6)-D-glucan derived from yeast on natural killer (NK) cells and breast cancer cell lines in 2D and 3D cultures. BMC Cancer. 2024;24:339. 10.1186/s12885-024-11979-3
- He F, Xie C, Xu X. Hyaluronic acid-modified yeast β-glucan particles delivering doxorubicin for treatment of breast cancer. Carbohydr Polym. 2023;314:120907. 10.1016/j.carbpol.2023.120907
- Elwakkad A, Gamal El Din AA, Saleh HA, Ibrahim NE, Hebishy MA, et al. Gold nanoparticles combined baker's yeast as a successful approach for breast cancer treatment. J Genet Eng Biotechnol. 2023;21:27. 10.1186/s43141-023-00481-1
- Baraka K, Abozahra R, Helmy MW, El Meniawy NSED, Abdelhamid SM. Investigation of the protective and therapeutic effects of and in a breast cancer mouse model. AIMS Microbiol. 2022;8:193. 10.3934/microbiol.2022016
- Jing Z, Wang S, Xu K, Tang Q, Li W, et al. A Potent Micron Neoantigen Tumor Vaccine GP-Neoantigen Induces Robust Antitumor Activity in Multiple Tumor Models. Adv Sci (Weinh). 2022;9:e2201496. 10.1002/advs.202201496
- Pakbin B, Dibazar SP, Allahyari S, Javadi M, Amani Z, et al. Anticancer Properties of Probiotic Saccharomyces boulardii Supernatant on Human Breast Cancer Cells. Probiotics Antimicrob Proteins. 2022;14:1130. 10.1007/s12602-021-09756-w
