Last update
3/27/2026
Reviewed By
Overview
SCIENTIFIC SCORE
Moderately Effective
Based on 7 Researches
8
USERS' SCORE
Good
Based on 441 Reviews
8.1
Supplement Facts
Serving Size: 1 Capsule
Amount Per Serving
%DV
Saccharomyces boulardii(an S. cerevisiae Strain)
250 mg(5 Billion CFU)
†
MOS Yeast Fraction(Min. 35% Manno-oligosaccharides [MOS]) (S. cerevisiae)
200 mg
†
Top Medical Research Studies
8
Probiotic shows promise against candidiasis
We investigated the role of Saccharomyces boulardii, a helpful probiotic, in combating Candida albicans, a troublesome pathogen for those with weakened immune systems.
By examining the effects on specific human intestinal cell lines, we found that both S. boulardii and its culture extract notably reduced C. albicans' ability to adhere to these cells.
Additionally, the extract lowered the production of harmful inflammatory markers, suggesting it may help manage inflammation linked to these infections. Overall, our findings highlight the potential of S. boulardii as a supportive treatment against candidiasis.
By examining the effects on specific human intestinal cell lines, we found that both S. boulardii and its culture extract notably reduced C. albicans' ability to adhere to these cells.
Additionally, the extract lowered the production of harmful inflammatory markers, suggesting it may help manage inflammation linked to these infections. Overall, our findings highlight the potential of S. boulardii as a supportive treatment against candidiasis.
Read More
8
Saccharomyces boulardii reduces Candida translocation
We explored how orally administered Saccharomyces boulardii affects the translocation of Candida albicans from the gastrointestinal tract in mice. In this study, antibiotic-treated mice were challenged with C. albicans to simulate intestinal overgrowth.
We found that S. boulardii reduced the likelihood of C. albicans being detected in lymph nodes for healthy mice, but it did not lower its concentration there. However, in mice subjected to immunosuppression, S. boulardii significantly decreased both the incidence and the quantities of C. albicans translocation to various organs, showcasing its potential benefits in immunocompromised situations.
We found that S. boulardii reduced the likelihood of C. albicans being detected in lymph nodes for healthy mice, but it did not lower its concentration there. However, in mice subjected to immunosuppression, S. boulardii significantly decreased both the incidence and the quantities of C. albicans translocation to various organs, showcasing its potential benefits in immunocompromised situations.
Read More
9
We aimed to understand how Saccharomyces boulardii affects Candida albicans in a mouse model with chemically-induced colitis. By administering S. boulardii alongside C. albicans, we found that the yeast significantly reduced C. albicans colonization and inflammation related to the colitis.
Mice treated with S. boulardii showed lower levels of inflammatory markers and less severe symptoms than those that did not receive the yeast. Overall, our findings suggest that S. boulardii can help combat C. albicans and alleviate inflammation in this context.
Mice treated with S. boulardii showed lower levels of inflammatory markers and less severe symptoms than those that did not receive the yeast. Overall, our findings suggest that S. boulardii can help combat C. albicans and alleviate inflammation in this context.
Read More
Most Useful Reviews
9
Effective for thrush
418 people found this helpful
This tool was recommended by my gynecologist. She mentioned that after taking them for 2-3 months, one can forget about thrush for an extended period. I was weary of this issue; the effect of suppositories and other medications lasted only a month before the problem returned. The doctor indicated that this female issue originates from the intestines and its flora. After using it, I felt great comfort in my tummy, and my gastrointestinal issues vanished during treatment. Now everything is alright (it’s been 3 months since I last took it), and my skin looks clean and smooth. I plan to take them twice a year for two months. I will definitely order again.
Read More
9
Helps with eczema
304 people found this helpful
I discovered this drug by chance during a course with a nutritionist on restoring the gastrointestinal tract. I used Sakhromyceta bulordi + mos for 3 months and gave it to my husband, who suffered from severe eczema on his scalp that only provided temporary relief with ointments. I also struggled with a persistent discharge for years. Following a strict diet and taking Hafitol, I tried Saccharomyces bulordi + Mos and am thrilled with the results – I even stopped needing daily pads. It effectively dissolves the films caused by Candidiasis. A must-try!
Read More
9
Essential addition
59 people found this helpful
Boulardi saccharomycetes counteract various pathogenic microorganisms, including Candida. They are advantageous because they do not settle in the intestines, allowing beneficial microorganisms to thrive. They effectively neutralised toxins and suppressed harmful microflora, demonstrating their efficacy for gastrointestinal disorders, including diarrhoea.
Read More
Medical Researches
SCIENTIFIC SCORE
Moderately Effective
Based on 7 Researches
8
- All Researches
9
We explored how introducing probiotics in a pediatric intensive care unit (PICU) affected the prevalence of candidemia and candiduria in children receiving broad-spectrum antibiotics. In a retrospective study comparing two groups, we found that candidemia rates dropped significantly from 3.7% in the control group to 1.2% among those taking probiotics. Similarly, candiduria fell from 22% to 10.7%. These results suggest that probiotics may help reduce the risk of these fungal infections in critically ill children.
Read More
9
We aimed to understand how Saccharomyces boulardii affects Candida albicans in a mouse model with chemically-induced colitis. By administering S. boulardii alongside C. albicans, we found that the yeast significantly reduced C. albicans colonization and inflammation related to the colitis.
Mice treated with S. boulardii showed lower levels of inflammatory markers and less severe symptoms than those that did not receive the yeast. Overall, our findings suggest that S. boulardii can help combat C. albicans and alleviate inflammation in this context.
Mice treated with S. boulardii showed lower levels of inflammatory markers and less severe symptoms than those that did not receive the yeast. Overall, our findings suggest that S. boulardii can help combat C. albicans and alleviate inflammation in this context.
Read More
8
Our investigation looked at how the probiotic yeast Saccharomyces boulardii can help combat candidiasis, particularly by reducing the virulence of Candida albicans. We found that S. boulardii secretes compounds that diminish C. albicans's ability to grow filaments, adhere, and form biofilms. Specifically, capric acid was identified as the main contributor to these inhibitory effects. While capric acid had a significant impact, it was less effective than the full yeast extract, which had additional factors that help suppress C. albicans adhesion.
Read More
8
Probiotic shows promise against candidiasis
We investigated the role of Saccharomyces boulardii, a helpful probiotic, in combating Candida albicans, a troublesome pathogen for those with weakened immune systems.
By examining the effects on specific human intestinal cell lines, we found that both S. boulardii and its culture extract notably reduced C. albicans' ability to adhere to these cells.
Additionally, the extract lowered the production of harmful inflammatory markers, suggesting it may help manage inflammation linked to these infections. Overall, our findings highlight the potential of S. boulardii as a supportive treatment against candidiasis.
By examining the effects on specific human intestinal cell lines, we found that both S. boulardii and its culture extract notably reduced C. albicans' ability to adhere to these cells.
Additionally, the extract lowered the production of harmful inflammatory markers, suggesting it may help manage inflammation linked to these infections. Overall, our findings highlight the potential of S. boulardii as a supportive treatment against candidiasis.
Read More
8
Saccharomyces boulardii reduces Candida translocation
We explored how orally administered Saccharomyces boulardii affects the translocation of Candida albicans from the gastrointestinal tract in mice. In this study, antibiotic-treated mice were challenged with C. albicans to simulate intestinal overgrowth.
We found that S. boulardii reduced the likelihood of C. albicans being detected in lymph nodes for healthy mice, but it did not lower its concentration there. However, in mice subjected to immunosuppression, S. boulardii significantly decreased both the incidence and the quantities of C. albicans translocation to various organs, showcasing its potential benefits in immunocompromised situations.
We found that S. boulardii reduced the likelihood of C. albicans being detected in lymph nodes for healthy mice, but it did not lower its concentration there. However, in mice subjected to immunosuppression, S. boulardii significantly decreased both the incidence and the quantities of C. albicans translocation to various organs, showcasing its potential benefits in immunocompromised situations.
Read More
User Reviews
USERS' SCORE
Good
Based on 441 Reviews
8.1
- All Reviews
- Positive Reviews
- Negative Reviews
9
Effective for thrush
418 people found this helpful
This tool was recommended by my gynecologist. She mentioned that after taking them for 2-3 months, one can forget about thrush for an extended period. I was weary of this issue; the effect of suppositories and other medications lasted only a month before the problem returned. The doctor indicated that this female issue originates from the intestines and its flora. After using it, I felt great comfort in my tummy, and my gastrointestinal issues vanished during treatment. Now everything is alright (it’s been 3 months since I last took it), and my skin looks clean and smooth. I plan to take them twice a year for two months. I will definitely order again.
Read More
9
Helps with eczema
304 people found this helpful
I discovered this drug by chance during a course with a nutritionist on restoring the gastrointestinal tract. I used Sakhromyceta bulordi + mos for 3 months and gave it to my husband, who suffered from severe eczema on his scalp that only provided temporary relief with ointments. I also struggled with a persistent discharge for years. Following a strict diet and taking Hafitol, I tried Saccharomyces bulordi + Mos and am thrilled with the results – I even stopped needing daily pads. It effectively dissolves the films caused by Candidiasis. A must-try!
Read More
9
Essential addition
59 people found this helpful
Boulardi saccharomycetes counteract various pathogenic microorganisms, including Candida. They are advantageous because they do not settle in the intestines, allowing beneficial microorganisms to thrive. They effectively neutralised toxins and suppressed harmful microflora, demonstrating their efficacy for gastrointestinal disorders, including diarrhoea.
Read More
9
Digestive aid
33 people found this helpful
Irreplaceable helpers! I began taking Boulardi saccharomycetes after battling rotavirus. For weeks, my gastrointestinal tract was troubled, but after two days of taking these, I could see improvement in digestion. A week later, I felt immense relief—Boulardi works! My husband and I used them again during ARVI, leading to easier recovery. They are crucial when taking antibiotics as well. This yeast has proved effective and safe, confirmed by health organisations. They stimulate enzyme activity, eliminate pathogens, and support gut flora.
Read More
10
Helps babies with candidiasis
30 people found this helpful
Using Saccharomyces boulardii helped my baby tackle intestinal candidiasis. I mixed the capsule contents with morning porridge and followed up with white coal to prevent constipation and included probiotics and vitamins. The regimen lasted seven days, three times daily, and I found that this approach efficiently treated other ailments without complicating the situation. I highly recommend this treatment for good health for children.
Read More
Frequently Asked Questions
9
Symptoms disappeared
After several days of taking it, flatulence and symptoms of candidiasis disappeared. Highly recommended!
9
Rapid relief from thrush
4 people found this helpful
I began taking this for acute thrush and noticed results within days; the symptoms normalised quickly. However, I realised that the condition returned once I stopped. It's clear that nothing can fully resolve thrush without adhering to a strict diet, eliminating sugars and many carbohydrates while cleansing the body. The hard detox from Candida, while avoiding its food sources, is crucial for curing thrush effectively.
9
Perfectly removes candidiasis
I take it periodically every 6-9 months. I have a problem with candidiasis, and this product effectively removes candidiasis without harming the good flora.
9
Got rid of candidiasis
I take it in the morning on an empty stomach, and my peristalsis has significantly improved. Regular intake of probiotics has helped me to get rid of candidiasis, which frequently occurred with any hypothermia.
7.5
Resolved recurring candidiasis
2 people found this helpful
This dietary supplement aided my recurrent intimate candidiasis; the bloating in my abdomen has disappeared. I keep it in the refrigerator, although it's stated that it can be stored at room temperature.
8.5
Excellent for candidiasis
I took Saccharomycetes boulardii during treatment for candidiasis, using it as an anti-filming agent. It performed excellently when combined with candidiasis treatment. I took 1 to 2 capsules daily, 1.5 hours after eating. The capsules are medium-sized and easy to swallow. I was pleased with the quality of the product and recommend it!
7.5
Ongoing treatment
They helped me with candidiasis, and now I take them consistently every morning, half an hour before breakfast.
8
Our investigation looked at how the probiotic yeast Saccharomyces boulardii can help combat candidiasis, particularly by reducing the virulence of Candida albicans. We found that S. boulardii secretes compounds that diminish C. albicans's ability to grow filaments, adhere, and form biofilms. Specifically, capric acid was identified as the main contributor to these inhibitory effects. While capric acid had a significant impact, it was less effective than the full yeast extract, which had additional factors that help suppress C. albicans adhesion.
9
We aimed to understand how Saccharomyces boulardii affects Candida albicans in a mouse model with chemically-induced colitis. By administering S. boulardii alongside C. albicans, we found that the yeast significantly reduced C. albicans colonization and inflammation related to the colitis.
Mice treated with S. boulardii showed lower levels of inflammatory markers and less severe symptoms than those that did not receive the yeast. Overall, our findings suggest that S. boulardii can help combat C. albicans and alleviate inflammation in this context.
Mice treated with S. boulardii showed lower levels of inflammatory markers and less severe symptoms than those that did not receive the yeast. Overall, our findings suggest that S. boulardii can help combat C. albicans and alleviate inflammation in this context.
7
We reviewed placebo-controlled studies to see how biotherapeutic agents, like Saccharomyces boulardii, can help treat infections, including candidiasis. While many studies showed promising results in preventing antibiotic-related diarrhea and treating other infections, evidence specifically supporting the effectiveness of S. boulardii for vaginal candidiasis is limited. We found few adverse effects, but the sample sizes in studies were often small. Overall, it's a call to further research these microorganisms to potentially reduce our reliance on conventional antibiotics.
References
- Kumar S, Singhi S, Chakrabarti A, Bansal A, Jayashree M. Probiotic use and prevalence of candidemia and candiduria in a PICU. Pediatr Crit Care Med. 2013;14:e409. 10.1097/PCC.0b013e31829f5d88
- Murzyn A, Krasowska A, Stefanowicz P, Dziadkowiec D, Łukaszewicz M. Capric acid secreted by S. boulardii inhibits C. albicans filamentous growth, adhesion and biofilm formation. PLoS One. 2010;5:e12050. 10.1371/journal.pone.0012050
- Murzyn A, Krasowska A, Augustyniak D, Majkowska-Skrobek G, Łukaszewicz M, et al. The effect of Saccharomyces boulardii on Candida albicans-infected human intestinal cell lines Caco-2 and Intestin 407. FEMS Microbiol Lett. 2010;310:17. 10.1111/j.1574-6968.2010.02037.x
- Jawhara S, Poulain D. Saccharomyces boulardii decreases inflammation and intestinal colonization by Candida albicans in a mouse model of chemically-induced colitis. Med Mycol. 2007;45:691. PubMed
- Algin C, Sahin A, Kiraz N, Sahintürk V, Ihtiyar E. Effectiveness of bombesin and Saccharomyces boulardii against the translocation of Candida albicans in the digestive tract in immunosuppressed rats. Surg Today. 2005;35:869. PubMed
- Elmer GW, Surawicz CM, McFarland LV. Biotherapeutic agents. A neglected modality for the treatment and prevention of selected intestinal and vaginal infections. JAMA. 1996;275:870. PubMed
- Berg R, Bernasconi P, Fowler D, Gautreaux M. Inhibition of Candida albicans translocation from the gastrointestinal tract of mice by oral administration of Saccharomyces boulardii. J Infect Dis. 1993;168:1314. PubMed
Data last updated:
