Last update
3/27/2026

Overview

SCIENTIFIC SCORE
Possibly Effective
Based on 2 Researches
7
USERS' SCORE
Moderately Good
Based on 5 Reviews
7.7
Supplement Facts
Serving Size: 1 Capsule
Amount Per Serving
%DV
Saccharomyces boulardii(an S. cerevisiae Strain)
250 mg(5 Billion CFU)
MOS Yeast Fraction(Min. 35% Manno-oligosaccharides [MOS]) (S. cerevisiae)
200 mg
📅 Last updated:

Top Medical Research Studies

7
Potential benefits of yeast supplements
We explored the impact of "Nagipol," a supplement made from beer yeasts, on chronic fatigue syndrome (CFS). Our clinical study indicated that "Nagipol" could improve the clinical status of CFS patients. It appears to help enhance cognitive functions and stabilize emotional symptoms while also normalizing certain blood parameters.

While these findings are promising, it’s important to note that further research is needed to fully confirm these benefits, especially regarding its role in diet therapy for individuals dealing with CFS.
Read More
7
Beta-glucan alleviates cognitive fatigue
We conducted a rigorous 36-week study with 65 patients diagnosed with Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS). Participants were given either yeast-derived beta-glucan with vitamins or a placebo.

The results revealed that those taking beta-glucan showed notable improvements in cognitive fatigue compared to those on the placebo. This suggests that beta-glucan could be a promising nutritional supplement for easing cognitive symptoms associated with ME/CFS.

However, more research is needed to fully understand its benefits and mechanisms.
Read More

Most Useful Reviews

7
Reduced fatigue
24 people found this helpful
Although I purchased a jacket, I felt my symptoms of leaky gut and allergies were prevalent. Despite trying various supplements, I opted for this one as my gut environment seemed poor. I noticed no sudden stomach drops, and my excessive appetite was suppressed. While I can't comment on long-term effects yet, I've felt less fatigued after a month of taking two tablets daily. I chose this probiotic due to its intriguing packaging, and it seems to have been the right decision.
Read More
0
No noticeable difference
2 people found this helpful
I have been purchasing from iHerb for over a decade, spending thousands on supplements for chronic fatigue syndrome. While I believe this supplement is legitimate and of good quality, I personally noticed no improvement in my health, despite taking it for several weeks. However, I found Thorne's multivitamins effective, as they made me feel more energised shortly after consumption. Please like if this review has helped you.
Read More
6
Reduced discomfort
I experienced less stomach pain after using this supplement. My irritable bowel syndrome has improved significantly, which has greatly enhanced my well-being.
Read More

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Medical Researches

SCIENTIFIC SCORE
Possibly Effective
Based on 2 Researches
7
  • All Researches
7
Beta-glucan alleviates cognitive fatigue
We conducted a rigorous 36-week study with 65 patients diagnosed with Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS). Participants were given either yeast-derived beta-glucan with vitamins or a placebo.

The results revealed that those taking beta-glucan showed notable improvements in cognitive fatigue compared to those on the placebo. This suggests that beta-glucan could be a promising nutritional supplement for easing cognitive symptoms associated with ME/CFS.

However, more research is needed to fully understand its benefits and mechanisms.
Read More
7
Potential benefits of yeast supplements
We explored the impact of "Nagipol," a supplement made from beer yeasts, on chronic fatigue syndrome (CFS). Our clinical study indicated that "Nagipol" could improve the clinical status of CFS patients. It appears to help enhance cognitive functions and stabilize emotional symptoms while also normalizing certain blood parameters.

While these findings are promising, it’s important to note that further research is needed to fully confirm these benefits, especially regarding its role in diet therapy for individuals dealing with CFS.
Read More

User Reviews

USERS' SCORE
Moderately Good
Based on 5 Reviews
7.7
  • All Reviews
  • Positive Reviews
  • Negative Reviews
7
Reduced fatigue
24 people found this helpful
Although I purchased a jacket, I felt my symptoms of leaky gut and allergies were prevalent. Despite trying various supplements, I opted for this one as my gut environment seemed poor. I noticed no sudden stomach drops, and my excessive appetite was suppressed. While I can't comment on long-term effects yet, I've felt less fatigued after a month of taking two tablets daily. I chose this probiotic due to its intriguing packaging, and it seems to have been the right decision.
Read More
0
No noticeable difference
2 people found this helpful
I have been purchasing from iHerb for over a decade, spending thousands on supplements for chronic fatigue syndrome. While I believe this supplement is legitimate and of good quality, I personally noticed no improvement in my health, despite taking it for several weeks. However, I found Thorne's multivitamins effective, as they made me feel more energised shortly after consumption. Please like if this review has helped you.
Read More
6
Reduced discomfort
I experienced less stomach pain after using this supplement. My irritable bowel syndrome has improved significantly, which has greatly enhanced my well-being.
Read More
2
No improvement experienced
I purchased this supplement based on recommendations for irritable bowel syndrome. Unfortunately, it did not alleviate my symptoms and even worsened them.
Read More
8.5
Positive effects noticed
12 people found this helpful
With leaky gut syndrome, I found this supplement effective. It has yielded the most positive results of any I have tried so far. Additionally, I use it alongside another probiotic complex from Jarrow for enhanced benefits.
Read More

Frequently Asked Questions

7
Reduced fatigue
24 people found this helpful
Although I purchased a jacket, I felt my symptoms of leaky gut and allergies were prevalent. Despite trying various supplements, I opted for this one as my gut environment seemed poor. I noticed no sudden stomach drops, and my excessive appetite was suppressed. While I can't comment on long-term effects yet, I've felt less fatigued after a month of taking two tablets daily. I chose this probiotic due to its intriguing packaging, and it seems to have been the right decision.
0
No noticeable difference
2 people found this helpful
I have been purchasing from iHerb for over a decade, spending thousands on supplements for chronic fatigue syndrome. While I believe this supplement is legitimate and of good quality, I personally noticed no improvement in my health, despite taking it for several weeks. However, I found Thorne's multivitamins effective, as they made me feel more energised shortly after consumption. Please like if this review has helped you.
6
Reduced discomfort
I experienced less stomach pain after using this supplement. My irritable bowel syndrome has improved significantly, which has greatly enhanced my well-being.
2
No improvement experienced
I purchased this supplement based on recommendations for irritable bowel syndrome. Unfortunately, it did not alleviate my symptoms and even worsened them.
8.5
Positive effects noticed
12 people found this helpful
With leaky gut syndrome, I found this supplement effective. It has yielded the most positive results of any I have tried so far. Additionally, I use it alongside another probiotic complex from Jarrow for enhanced benefits.
7
Beta-glucan alleviates cognitive fatigue
We conducted a rigorous 36-week study with 65 patients diagnosed with Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS). Participants were given either yeast-derived beta-glucan with vitamins or a placebo.

The results revealed that those taking beta-glucan showed notable improvements in cognitive fatigue compared to those on the placebo. This suggests that beta-glucan could be a promising nutritional supplement for easing cognitive symptoms associated with ME/CFS.

However, more research is needed to fully understand its benefits and mechanisms.
7
Potential benefits of yeast supplements
We explored the impact of "Nagipol," a supplement made from beer yeasts, on chronic fatigue syndrome (CFS). Our clinical study indicated that "Nagipol" could improve the clinical status of CFS patients. It appears to help enhance cognitive functions and stabilize emotional symptoms while also normalizing certain blood parameters.

While these findings are promising, it’s important to note that further research is needed to fully confirm these benefits, especially regarding its role in diet therapy for individuals dealing with CFS.

References

  1. Lacasa M, Alegre-Martin J, Sentañes RS, Varela-Sende L, Jurek J, et al. Yeast Beta-Glucan Supplementation with Multivitamins Attenuates Cognitive Impairments in Individuals with Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: A Randomized, Double-Blind, Placebo-Controlled Trial. Nutrients. 2023;15. 10.3390/nu15214504
  2. Dotsenko VA, Mosiĭchuk LV, Paramonov AE. [Biologically active food additives for correction of the chronic fatigue syndrome]. Vopr Pitan. 2004;73:17. PubMed
Data last updated:
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