Last update
5/12/2025
Research Authors

Overview

SCIENTIFIC SCORE
Questionable
Based on 2 Researches
6.5
USERS' SCORE
Good
Based on 74 Reviews
8.2
Supplement Facts
Serving Size:  1 Capsule
Amount Per Serving
%DV
Proprietary Probiotic Blend 
134 mg (1 Billion CFU§)
Lactobacillus rhamnosus (GR-1®) 
 
 
Lactobacillus reuteri (RC-14®) 
 
 

Top Medical Research Studies

8
GCL1815 reduces cold symptoms
We looked into how GCL1815, a type of lactic acid bacterium, might aid in preventing the common cold. In our randomized, double-blind study with 200 participants, we found that those who took GCL1815 capsules for eight weeks had significantly lower symptoms of colds, like fatigue and nasal congestion, compared to those on placebo. We also observed key immune responses related to dendritic cell activation that were notably more enhanced in participants taking GCL1815. This suggests that GCL1815 is promising in boosting the body’s defenses against the cold.
Read More
5
Lactobacillus impact on immunity
We conducted a pilot study to explore the effects of heat-sterilized Lactobacillus crispatus strain KT-11 on immune function in healthy adults. Over four weeks, 22 participants took either KT-11 or a placebo. We observed that those taking KT-11 had higher counts of certain immune cells and reported fewer cold-like symptoms, particularly fatigue. However, there were no significant increases in antibodies related to SARS-CoV-2. This indicates potential benefits of KT-11 for immune activity, suggesting further studies on its effectiveness are warranted.
Read More

Most Useful Reviews

9
Balances pH levels
10 people found this helpful
Definitely give these a try! I was thrilled to discover these after my GYN suggested probiotic inserts due to my migraines making oral ones impossible. Suffering from chronic infections, this has been the only product that helped balance my pH levels almost immediately. After testing against a new body wash that usually induces infections, I inserted two capsules daily for three days, and my symptoms cleared up completely. They came well packed in cold packs, but just ensure you track your package as they don't mark it as needing refrigeration.
Read More
10
Pain relief achieved
9 people found this helpful
As someone with chronic gynecological issues, I often faced painful secretions. After trying these probiotics, I began taking two pills daily. Remarkably, I felt pain relief the very next day, with no secretions to be found. This solution transformed my experience, allowing me to abandon previous treatments.
Read More
9
Water intake helps
7 people found this helpful
Works! This product is effective. For others suffering from recurring yeast infections, reducing sugars and consuming light carbs has helped me. Drinking plenty of water flushes the bladder, which pairs well with this product. I recommend it to others, especially since ordering from the seller includes overnight shipping in a cold pack!
Read More

Medical Researches

SCIENTIFIC SCORE
Questionable
Based on 2 Researches
6.5
  • All Researches
8
GCL1815 reduces cold symptoms
We looked into how GCL1815, a type of lactic acid bacterium, might aid in preventing the common cold. In our randomized, double-blind study with 200 participants, we found that those who took GCL1815 capsules for eight weeks had significantly lower symptoms of colds, like fatigue and nasal congestion, compared to those on placebo. We also observed key immune responses related to dendritic cell activation that were notably more enhanced in participants taking GCL1815. This suggests that GCL1815 is promising in boosting the body’s defenses against the cold.
Read More
5
Lactobacillus impact on immunity
We conducted a pilot study to explore the effects of heat-sterilized Lactobacillus crispatus strain KT-11 on immune function in healthy adults. Over four weeks, 22 participants took either KT-11 or a placebo. We observed that those taking KT-11 had higher counts of certain immune cells and reported fewer cold-like symptoms, particularly fatigue. However, there were no significant increases in antibodies related to SARS-CoV-2. This indicates potential benefits of KT-11 for immune activity, suggesting further studies on its effectiveness are warranted.
Read More

User Reviews

USERS' SCORE
Good
Based on 74 Reviews
8.2
  • All Reviews
  • Positive Reviews
  • Negative Reviews
9
Balances pH levels
10 people found this helpful
Definitely give these a try! I was thrilled to discover these after my GYN suggested probiotic inserts due to my migraines making oral ones impossible. Suffering from chronic infections, this has been the only product that helped balance my pH levels almost immediately. After testing against a new body wash that usually induces infections, I inserted two capsules daily for three days, and my symptoms cleared up completely. They came well packed in cold packs, but just ensure you track your package as they don't mark it as needing refrigeration.
Read More
10
Pain relief achieved
9 people found this helpful
As someone with chronic gynecological issues, I often faced painful secretions. After trying these probiotics, I began taking two pills daily. Remarkably, I felt pain relief the very next day, with no secretions to be found. This solution transformed my experience, allowing me to abandon previous treatments.
Read More
9
Water intake helps
7 people found this helpful
Works! This product is effective. For others suffering from recurring yeast infections, reducing sugars and consuming light carbs has helped me. Drinking plenty of water flushes the bladder, which pairs well with this product. I recommend it to others, especially since ordering from the seller includes overnight shipping in a cold pack!
Read More
9
Immediate relief
6 people found this helpful
FINALLY! Something that works!!! I will admit to being a sceptic. Like many, I have tried countless prescriptions, herbal remedies, and cleanses. This is great, and it works almost immediately. The odour vanished within two days along with the other discomforts from BV and yeast. I highly recommend it. I did receive a shipment that was not refrigerated, but I found it can be okay for up to 7 days as long as it remains cold. Now that I've discovered this wonderful product, I never want to be without it again, although I'll purchase from a local shop since they keep it refrigerated.
Read More
9
No more infections
6 people found this helpful
It works! I have dealt with recurrent yeast infections for six months, trying various prescriptions and home remedies without success. After using this product, despite it not being kept cold during shipping, I have had no further infections for over a month. I started taking 2-4 pills daily for the first week, then reduced to one daily. I only give it four stars as there was no option for ice packs during shipping, which could have enhanced potency. Regardless, it works without question!
Read More

Frequently Asked Questions

9
Immediate effects
The only downside is the scent reminiscent of old cosmetics. However, I've noticed a marked reduction in my cold just two days after starting it. I’ve been taking it consistently, and I believe it’s a commendable product for disease prevention.
9
Effective for cold
14 people found this helpful
The treatment for my yeast infection and cold was very effective. Within four days of taking the medicine, I noted improvements that lasted for about a month. I was pleased with the outcome. It's vital to ensure sufficient Lactobacillus; without it, I wouldn’t recommend buying it as it’s essential for relief.
7.5
Improved cold condition
4 people found this helpful
After a month of use, I have noticed a significant decline in my cold symptoms. I previously experienced discolouration in my cold, but now it improves quickly after consumption. Additionally, my urinary issues seem better, likely due to the probiotics. I intend to keep taking it.
9
Significant cold reduction
2 people found this helpful
After two years of consistent use, I find this product suits me well. I take a pill each morning on an empty stomach. Since starting this routine, my cold symptoms have significantly decreased, improving my overall wellbeing.
10
Pain relief achieved
9 people found this helpful
As someone with chronic gynecological issues, I often faced painful secretions. After trying these probiotics, I began taking two pills daily. Remarkably, I felt pain relief the very next day, with no secretions to be found. This solution transformed my experience, allowing me to abandon previous treatments.
9
Reduced cold sores
2 people found this helpful
By chance, I purchased this product and later ordered it from iHerb. I was pleasantly surprised by the substantial reduction in my cold sores and vaginitis cases. I even recommended it to my brother, who found it helpful for menstrual cramps.
9
Miraculous reduction
I feel less cold after consuming this lactobacillus. It has miraculously reduced my cold sensation. I plan to repurchase it.
9
Less cold feeling
I'm also taking regular lactic acid bacteria, so I'm uncertain if it's from this drug, but I feel I have less cold after consistent use.
9
Significant improvement
I've seen a noticeable reduction in cold discharge! I’ve always dealt with a lot of cold, but this product significantly decreases it. I initially took three pills consistently, and I've been recommending it to others. I am genuinely pleased with the results.
9
Relieved symptoms
1 people found this helpful
I've tried lactic acid bacteria before, but this is the first time I've bought female-specific strains. Depending on my condition, I often experience a lot of cold and some vaginitis symptoms (no itchiness), but since starting this, my cold has become clearer and the vaginitis symptoms have significantly improved. It's essential to take it regularly to prevent recurrence. Initially, I took two tablets when symptoms were severe, but usually, just one suffices. I wish I had discovered this product sooner! Highly recommended for women.
9
Works quickly
I purchased vaginal lactobacillus due to dryness and cold. It's small and easy to swallow, with meticulous packaging. It seems to take effect quickly after steady use for about two weeks.
5
Lactobacillus impact on immunity
We conducted a pilot study to explore the effects of heat-sterilized Lactobacillus crispatus strain KT-11 on immune function in healthy adults. Over four weeks, 22 participants took either KT-11 or a placebo. We observed that those taking KT-11 had higher counts of certain immune cells and reported fewer cold-like symptoms, particularly fatigue. However, there were no significant increases in antibodies related to SARS-CoV-2. This indicates potential benefits of KT-11 for immune activity, suggesting further studies on its effectiveness are warranted.
8
GCL1815 reduces cold symptoms
We looked into how GCL1815, a type of lactic acid bacterium, might aid in preventing the common cold. In our randomized, double-blind study with 200 participants, we found that those who took GCL1815 capsules for eight weeks had significantly lower symptoms of colds, like fatigue and nasal congestion, compared to those on placebo. We also observed key immune responses related to dendritic cell activation that were notably more enhanced in participants taking GCL1815. This suggests that GCL1815 is promising in boosting the body’s defenses against the cold.

References

  1. Watanabe I, Suzuki N, Takara T. Supplementation with heat-sterilized Lactobacillus crispatus strain KT-11 stimulates the T cell-related immune function of healthy Japanese adults: A pilot randomized, placebo-controlled, double-blind, parallel-group study. Nutr Res. 2025;134:99. 10.1016/j.nutres.2024.12.004
  2. Wada H, Mawatari T, Saito Y, Azuma N, Iwama Y. Induces Two Types of Dendritic Cell Activation and Effectively Suppresses Onset of the Common Cold: A Randomized, Double-Blind, Placebo-Controlled Trial. Nutrients. 2024;17. 10.3390/nu17010101
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