In Vitro and In Vivo Evaluation of Lacticaseibacillus rhamnosus GG and Bifidobacterium lactis Bb12 Against Avian Pathogenic Escherichia coli and Identification of Novel Probiotic-Derived Bioactive Peptides.
We explored the potential of Lacticaseibacillus rhamnosus GG as a probiotic treatment against avian pathogenic E. coli (APEC) in chickens. Our study showed that this probiotic significantly reduced APEC colonization in the chickens' cecum and improved the balance of gut microbiota over a 24-hour period.
Through laboratory evaluations, we detected novel bioactive peptides in the probiotic's culture supernatants, which may contribute to its antibacterial properties. While the results are promising for poultry health, more research is needed to optimize its use in real farming conditions.
Read More
9
Bacteriocin LSB1 shows promise
Purification and characterization of Lactobacillus plantarum-derived bacteriocin with activity against Staphylococcus argenteus planktonic cells and biofilm.
We investigated the effectiveness of a new bacteriocin, LSB1, derived from Lactobacillus plantarum, in combating Staphylococcus argenteus—a harmful bacteria linked to food poisoning. This bacteriocin showed strong antibacterial properties, significantly inhibiting both the growth of planktonic and biofilm forms of the bacteria. LSB1 demonstrated notable stability under various conditions and a relatively low minimum inhibitory concentration. While the study indicates promising potential for LSB1 as a natural food preservative, more research is needed to fully understand its applications in food safety.
Read More
8
Lactobacillus reduces harmful E. coli
Impact of Lactobacillus-originated metabolites on enterohemorrhagic E. coli in rumen fluid.
We examined how Lactobacillus can help reduce harmful E. coli in the rumen, the large fermentation chamber in cows. By using live Lactobacillus casei and its metabolites in a controlled lab setting, we discovered that one specific treatment, Lactobacillus casei with peanut flour, decreased E. coli by 2.68 logs after 72 hours. This study indicates that the metabolites from Lactobacillus can positively influence the rumen environment, which could be helpful in managing foodborne pathogens from cattle.
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Most Useful Reviews
9
Quick cystitis relief
8 people found this helpful
This product helped with cystitis from the very first capsule! I recommend taking it alongside apple fibre from Now Foods. I was greatly helped by this combination, and I have found it effective.
Read More
7.5
Promotes bacterial balance
8 people found this helpful
I like this product very much! I recently experienced vaginitis, and upon researching, I found that this product can effectively maintain the good bacteria in the vagina, so my first purchase from iHerb was to buy it! After taking it for a month, if I notice excessive secretions or before my menstrual period, I will take two capsules. Usually, I take one capsule a day. I hope that consistent use will stabilise my condition. It's a reasonably priced health food that can support the body, and I will definitely continue to buy it in the future!
Read More
6
Effective for imbalance
1 people found this helpful
I like the quality of Jarrow supplements, including these probiotics. I’m currently taking them to normalise the female microflora, and I believe the supplement is working: itching and irritation have decreased (though I didn’t have thrush, just some imbalance). The capsules are very small, and the dosage is one piece per day with or without food, but it is advised not to wash it down with anything hot. The package contains 60 capsules, making it last for many weeks of use. The jar is protected by a foil membrane.
We explored how Lactobacillus K5 could help mice fend off E. coli O157:H7 infections. In our study, we observed that treating the mice with K5 ahead of exposure reduced their symptoms and helped maintain a healthier gut environment.
The benefits included less inflammation and more diversity in gut bacteria compared to untreated mice. Additionally, K5 boosted beneficial substances that protect the gut. Overall, this study shows promise for K5 in developing probiotic treatments for foodborne illnesses.
Read More
9
Bacteriocin LSB1 shows promise
Purification and characterization of Lactobacillus plantarum-derived bacteriocin with activity against Staphylococcus argenteus planktonic cells and biofilm.
We investigated the effectiveness of a new bacteriocin, LSB1, derived from Lactobacillus plantarum, in combating Staphylococcus argenteus—a harmful bacteria linked to food poisoning. This bacteriocin showed strong antibacterial properties, significantly inhibiting both the growth of planktonic and biofilm forms of the bacteria. LSB1 demonstrated notable stability under various conditions and a relatively low minimum inhibitory concentration. While the study indicates promising potential for LSB1 as a natural food preservative, more research is needed to fully understand its applications in food safety.
Read More
9
Lacticaseibacillus rhamnosus shows promise
In Vitro and In Vivo Evaluation of Lacticaseibacillus rhamnosus GG and Bifidobacterium lactis Bb12 Against Avian Pathogenic Escherichia coli and Identification of Novel Probiotic-Derived Bioactive Peptides.
We explored the potential of Lacticaseibacillus rhamnosus GG as a probiotic treatment against avian pathogenic E. coli (APEC) in chickens. Our study showed that this probiotic significantly reduced APEC colonization in the chickens' cecum and improved the balance of gut microbiota over a 24-hour period.
Through laboratory evaluations, we detected novel bioactive peptides in the probiotic's culture supernatants, which may contribute to its antibacterial properties. While the results are promising for poultry health, more research is needed to optimize its use in real farming conditions.
Read More
8
Lactobacillus reduces Campylobacter levels
Supplementation of lactobacillus-fermented rapeseed meal in broiler diet reduces Campylobacter jejuni cecal colonization and limits the l-tryptophan and l-histidine biosynthesis pathways.
In our examination, we assessed how Lactobacillus-fermented rapeseed meal (LFRM) influences the presence of Campylobacter jejuni in broilers exposed to contaminated litter.
The findings revealed that LFRM not only boosted growth performance but also significantly lowered the concentration of C. jejuni in the ceca.
This reduction appears linked to a decrease in critical gene pathways necessary for the bacteria's survival and virulence. Overall, LFRM shows promise as a helpful approach in curbing foodborne pathogens in poultry.
Read More
8
Lactobacillus reduces H. pylori impact
Immunomodulatory effects of live and pasteurized Lactobacillus crispatus strain RIGLD-1 on Helicobacter pylori-triggered inflammation in gastric epithelial cells in vitro.
We explored how live and pasteurized Lactobacillus crispatus strain RIGLD-1 could help fight against Helicobacter pylori, known to cause stomach inflammation and increase cancer risk. By using a variety of tests on gastric cells, we found that both forms of Lactobacillus significantly reduced the bacterium's ability to cling and invade these cells.
Additionally, they helped lower markers of inflammation in the cells, promoting a more balanced immune response. Overall, both live and pasteurized Lactobacillus crispatus showed promise as potential probiotics to combat H. pylori-related issues.
This product helped with cystitis from the very first capsule! I recommend taking it alongside apple fibre from Now Foods. I was greatly helped by this combination, and I have found it effective.
Read More
7.5
Promotes bacterial balance
8 people found this helpful
I like this product very much! I recently experienced vaginitis, and upon researching, I found that this product can effectively maintain the good bacteria in the vagina, so my first purchase from iHerb was to buy it! After taking it for a month, if I notice excessive secretions or before my menstrual period, I will take two capsules. Usually, I take one capsule a day. I hope that consistent use will stabilise my condition. It's a reasonably priced health food that can support the body, and I will definitely continue to buy it in the future!
Read More
6
Effective for imbalance
1 people found this helpful
I like the quality of Jarrow supplements, including these probiotics. I’m currently taking them to normalise the female microflora, and I believe the supplement is working: itching and irritation have decreased (though I didn’t have thrush, just some imbalance). The capsules are very small, and the dosage is one piece per day with or without food, but it is advised not to wash it down with anything hot. The package contains 60 capsules, making it last for many weeks of use. The jar is protected by a foil membrane.
Read More
7.5
Rapid vaginitis improvement
2 people found this helpful
Vaginitis troubled me for a year, but it has improved within a few days of taking this supplement, and I have not encountered any issues with constipation. It's a beneficial health product for women.
Read More
7.5
Improves gut discomfort
1 people found this helpful
I take this probiotic along with NOW Foods' Candida Support and feel a noticeable improvement in my intestinal condition; bloating and discomfort occur much less frequently. While my candida condition has improved, it’s not yet at 100% as I would like. I believe ongoing use for a couple of months will help me gauge the full effect. I haven’t had it sown for a long time, but occasionally, sensations occur that I can’t mistake for anything else; it's definitely her.
Read More
Frequently Asked Questions
Food poisoning, also known as foodborne illness, occurs when you consume contaminated food or beverages. This contamination can result from bacteria, viruses, parasites, or chemical substances that have infected the food. Common symptoms of food poisoning include nausea, vomiting, diarrhea, abdominal cramps, and fever, which usually appear within hours or days following the consumption of contaminated food. While most cases resolve on their own within a few days, some can lead to severe complications, especially in vulnerable populations such as young children, the elderly, and individuals with weakened immune systems.
To prevent food poisoning, it's essential to practice safe food handling techniques such as washing hands, cooking food to the appropriate temperatures, and avoiding cross-contamination between raw and cooked foods. Keeping your refrigerator at the correct temperature and being mindful of expiration dates can also help reduce the risk of foodborne illnesses. If you suspect that you have food poisoning, particularly if symptoms are severe or persistent, it's important to seek medical attention.
Lactobacillus is a genus of bacteria that plays a crucial role in the fermentation of various foods and is found naturally in the human gut. Known for their probiotic properties, strains of Lactobacillus are commonly utilized in the production of yogurt, sauerkraut, and other fermented products. They are characterized by their rod-shaped structure and ability to convert sugars into lactic acid, which not only helps preserve food but also contributes to the tangy flavor of fermented foods.
In addition to their culinary uses, Lactobacillus bacteria can offer several health benefits. They are known to support gut health by enhancing the balance of beneficial bacteria in the microbiome, potentially aiding in digestion and alleviating symptoms of issues like irritable bowel syndrome (IBS). Regular consumption of Lactobacillus-containing foods or supplements may also bolster the immune system and improve overall digestive health. With a growing interest in gut health, Lactobacillus remains a key player in both dietary and therapeutic contexts.
Lactobacillus, a type of beneficial bacteria commonly found in probiotics, is known for its role in supporting gut health and enhancing the immune system. While it’s not a cure for food poisoning, it can potentially help mitigate some symptoms associated with gastrointestinal distress. Lactobacillus can aid in restoring the natural balance of gut bacteria, which may be disrupted during a bout of food poisoning. This restoration can lead to improved digestion and reduced duration of diarrhea, an often unpleasant symptom.
Research indicates that probiotics, including Lactobacillus strains, can help in reducing the severity of acute gastroenteritis, which is often caused by foodborne pathogens. However, it’s important to note that probiotics should not replace conventional treatment methods for food poisoning, especially in severe cases. Staying hydrated and consulting a healthcare professional remains vital. If you're looking to support your gut health during recovery from food poisoning, incorporating Lactobacillus through probiotic supplements or fermented foods, such as yogurt, can be a helpful addition to your dietary regimen.
The use of Lactobacillus probiotics for food poisoning can vary significantly from person to person based on individual health, the severity of symptoms, and other factors. Generally, many individuals may start to notice improvements within 24 to 48 hours of starting a probiotic regimen, as Lactobacillus works to restore balance in the gut microbiome and help alleviate digestive distress. However, in some cases, it might take a bit longer—up to several days—to experience noticeable relief.
It's also important to note that probiotics are most effective when taken as part of a broader approach to recovery that includes hydration and, in some cases, dietary adjustments. If symptoms persist for longer than a few days or worsen, it's always wise to consult with a healthcare professional. They can provide tailored recommendations and ensure that any underlying issues are addressed properly.
The scientific research surrounding Lactobacillus strains presents promising evidence for their potential use in combating foodborne illnesses. Studies have shown that specific Lactobacillus strains, such as Lactobacillus K5, can significantly reduce symptoms of E. coli infections in mice, highlighting their role in maintaining gut health and managing inflammation [1]. Another study pointed to Lactobacillus pentosus showing antimicrobial properties against Bacillus cereus, a common foodborne pathogen, suggesting it could be utilized in food preservation [4]. However, while these findings support the probiotic properties of Lactobacillus in animal studies, their direct application and benefits in humans are still under exploration.
Additionally, Lactobacillus rhamnosus GR-1 exhibited protective effects on bovine mammary cells against Bacillus cereus, presenting an alternative to traditional antibiotics for enhancing food safety in dairy [6]. There’s also evidence that probiotics can enhance immune responses and intestinal health in models such as zebrafish, indicating a broader potential for improving food safety and public health [7]. However, it's important to note that more research is necessary to fully establish the effectiveness of these probiotics in human food poisoning cases.
Based on user reviews, many individuals have reported significant improvements in their symptoms after using this particular probiotic supplement. For instance, one user experienced immediate relief from cystitis after just one capsule, indicating a quick response to the product Read Review. Another user dealing with vaginitis noted a reduction in excessive secretions and discomfort after consistent use, suggesting that it effectively helps maintain healthy vaginal flora Read Review. Additionally, a user reported decreased itching and irritation after a period of use, demonstrating the product's potential in helping with microflora imbalances Read Review.
Furthermore, some users highlighted overall beneficial effects, such as reduced symptoms of bloating and discomfort in the gastrointestinal tract when combined with other supportive supplements Read Review. Another reviewer noted a remarkable improvement in vaginitis symptoms within days, asserting the product's efficacy for female health Read Review. While these anecdotal experiences paint a positive picture, it's essential to remember that individual results can vary, and ongoing use may be needed for optimal benefits.
Based on user reviews, several individuals have reported positive experiences when combining this probiotic supplement with other products to handle symptoms associated with food poisoning and other gastrointestinal issues. One user noted significant improvements in their intestinal condition while taking this probiotic alongside NOW Foods' Candida Support, stating that complaints of bloating and discomfort have diminished noticeably Read Review. This suggests that when paired with compatible supplements, the efficacy of the probiotic may be enhanced, promoting a more balanced gut health.
Additionally, another reviewer emphasized the benefits of taking the supplement with apple fiber from Now Foods, mentioning that this combination greatly helped their cystitis symptoms right from the first capsule Read Review. This indicates that users are finding success in combining the probiotic with other health-supporting options, potentially maximizing its effectiveness for various digestive and bacterial balance concerns. However, as with any supplement regimen, user experiences can vary, and continuous use might be needed to fully realize the benefits.
9
Quick cystitis relief
8 people found this helpful
This product helped with cystitis from the very first capsule! I recommend taking it alongside apple fibre from Now Foods. I was greatly helped by this combination, and I have found it effective.
7.5
Promotes bacterial balance
8 people found this helpful
I like this product very much! I recently experienced vaginitis, and upon researching, I found that this product can effectively maintain the good bacteria in the vagina, so my first purchase from iHerb was to buy it! After taking it for a month, if I notice excessive secretions or before my menstrual period, I will take two capsules. Usually, I take one capsule a day. I hope that consistent use will stabilise my condition. It's a reasonably priced health food that can support the body, and I will definitely continue to buy it in the future!
6
Effective for imbalance
1 people found this helpful
I like the quality of Jarrow supplements, including these probiotics. I’m currently taking them to normalise the female microflora, and I believe the supplement is working: itching and irritation have decreased (though I didn’t have thrush, just some imbalance). The capsules are very small, and the dosage is one piece per day with or without food, but it is advised not to wash it down with anything hot. The package contains 60 capsules, making it last for many weeks of use. The jar is protected by a foil membrane.
7.5
Improves gut discomfort
1 people found this helpful
I take this probiotic along with NOW Foods' Candida Support and feel a noticeable improvement in my intestinal condition; bloating and discomfort occur much less frequently. While my candida condition has improved, it’s not yet at 100% as I would like. I believe ongoing use for a couple of months will help me gauge the full effect. I haven’t had it sown for a long time, but occasionally, sensations occur that I can’t mistake for anything else; it's definitely her.
7.5
Rapid vaginitis improvement
2 people found this helpful
Vaginitis troubled me for a year, but it has improved within a few days of taking this supplement, and I have not encountered any issues with constipation. It's a beneficial health product for women.
9
Probiotic effects against E. coli
K5 Prevents Enterohaemorrhagic O157:H7 Infection in Mice through the Modulation of the Gut Microbiota.
We explored how Lactobacillus K5 could help mice fend off E. coli O157:H7 infections. In our study, we observed that treating the mice with K5 ahead of exposure reduced their symptoms and helped maintain a healthier gut environment.
The benefits included less inflammation and more diversity in gut bacteria compared to untreated mice. Additionally, K5 boosted beneficial substances that protect the gut. Overall, this study shows promise for K5 in developing probiotic treatments for foodborne illnesses.
8
Lactobacillus pentosus shows selective inhibition
Antimicrobial activity of Lactobacillus pentosus against the Bacillus cereus and Klebsiella pneumoniae strains.
We observed the potential of Lactobacillus pentosus to combat foodborne bacteria like Bacillus cereus and Klebsiella pneumoniae in our study. Using cell-free supernatants, we tested its antimicrobial effects through agar well diffusion methods.
While we noted a clear zone of inhibition against B. cereus, K. pneumoniae showed resistance and did not respond to treatment. The heat and pH stability of the bacteriocin from L. pentosus suggests it could be useful in the food industry for preventing food poisoning from B. cereus. However, it's not effective against K. pneumoniae.
7
LGR-1 shows potential against B. cereus
Lactobacillus rhamnosus GR-1 attenuates foodborne Bacillus cereus-induced NLRP3 inflammasome activity in bovine mammary epithelial cells by protecting intercellular tight junctions.
In our study, we examined how Lactobacillus rhamnosus GR-1 (LGR-1) could protect bovine mammary epithelial cells from the harmful effects of Bacillus cereus, a common foodborne pathogen. By pretreating cells with LGR-1, we found that it helped maintain tight junction integrity and lowered inflammatory responses triggered by B. cereus. This suggests that LGR-1 might serve as a probiotic alternative to antibiotics and could prevent mastitis in dairy cows, promoting better food safety overall. However, the results do not indicate any significant direct benefits for human food poisoning cases.
7
Probiotics enhance fish health outcomes
Effects of probiotics on Zebrafish model infected with Aeromonas hydrophila: spatial distribution, antimicrobial, and histopathological investigation.
This research investigates how probiotics, specifically Lactobacillus strains, can impact food-borne infections. Using a zebrafish model, we treated the fish with Lactobacillus delbrueckii, Lactobacillus acidophilus, or both, and compared them to a control group.
The results revealed that fish in the combination treatment group showed significant improvements in immune responses and intestinal health over time. Notably, they had higher villus lengths and an increased number of goblet cells. However, the control group, which was solely infected, did not fare as well.
Overall, probiotics demonstrate promise for enhancing food safety and public health in aquaculture.
References
Liu D, Li C, Cao T, Lv X, Yue Y, et al. K5 Prevents Enterohaemorrhagic O157:H7 Infection in Mice through the Modulation of the Gut Microbiota. Nutrients. 2024;16. doi:10.3390/nu16081164
Khattak F, Galgano S, Pedersen NR, Hui Y, Matthiesen R, et al. Supplementation of lactobacillus-fermented rapeseed meal in broiler diet reduces Campylobacter jejuni cecal colonization and limits the l-tryptophan and l-histidine biosynthesis pathways. J Sci Food Agric. 2024;104:5474. doi:10.1002/jsfa.13378
Fakharian F, Sadeghi A, Pouresmaeili F, Soleimani N, Yadegar A. Immunomodulatory effects of live and pasteurized Lactobacillus crispatus strain RIGLD-1 on Helicobacter pylori-triggered inflammation in gastric epithelial cells in vitro. Mol Biol Rep. 2023;50:6795. doi:10.1007/s11033-023-08596-x
Akhtar S, Nawaz SK. Antimicrobial activity of Lactobacillus pentosus against the Bacillus cereus and Klebsiella pneumoniae strains. New Microbiol. 2023;46:207.
Aditya A, Rahaman SO, Biswas D. Impact of Lactobacillus-originated metabolites on enterohemorrhagic E. coli in rumen fluid. FEMS Microbiol Ecol. 2022;98. doi:10.1093/femsec/fiac128
Shan Q, Liu N, Wang X, Zhu Y, Yin J, et al. Lactobacillus rhamnosus GR-1 attenuates foodborne Bacillus cereus-induced NLRP3 inflammasome activity in bovine mammary epithelial cells by protecting intercellular tight junctions. J Anim Sci Biotechnol. 2022;13:101. doi:10.1186/s40104-022-00752-w
Ehsannia S, Ahari H, Kakoolaki S, Anvar SA, Yousefi S. Effects of probiotics on Zebrafish model infected with Aeromonas hydrophila: spatial distribution, antimicrobial, and histopathological investigation. BMC Microbiol. 2022;22:167. doi:10.1186/s12866-022-02491-4
Zhang YM, Jiang YH, Li HW, Li XZ, Zhang QL. Purification and characterization of Lactobacillus plantarum-derived bacteriocin with activity against Staphylococcus argenteus planktonic cells and biofilm. J Food Sci. 2022;87:2718. doi:10.1111/1750-3841.16148
Kathayat D, Closs G, Helmy YA, Deblais L, Srivastava V, et al. In Vitro and In Vivo Evaluation of Lacticaseibacillus rhamnosus GG and Bifidobacterium lactis Bb12 Against Avian Pathogenic Escherichia coli and Identification of Novel Probiotic-Derived Bioactive Peptides. Probiotics Antimicrob Proteins. 2022;14:1012. doi:10.1007/s12602-021-09840-1