We investigated the effectiveness of probiotics sourced from Bulgarian cheese and shallot yogurt against common bacteria causing urinary tract infections (UTIs).
By isolating 100 strains from clinical samples and testing various probiotic strains, we found that certain probiotics showed encouraging antibacterial and antibiofilm activity.
Notably, strains M and B indicated strong antimicrobial effects without any harmful qualities. While these results are promising, we recognize that further research is essential to fully assess their therapeutic potential for UTIs.
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We investigated how by-products from Lactobacillus rhamnosus can affect uropathogenic Escherichia coli (UPEC), the bacteria commonly responsible for urinary tract infections (UTIs). Our findings revealed that lactic acid, hydrogen peroxide, and other compounds from these probiotics significantly inhibited the growth of UPEC.
Additionally, they reduced the production of proteins that help the bacteria cling to the urinary tract. This suggests that Lactobacillus rhamnosus and its by-products offer protective benefits against UTIs by combating harmful bacteria and reducing their ability to establish infections.
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Dietary supplement improves UTI outcomesEffects of a supplement associating strains and proanthocyanidin-rich plant extracts against recurrent uncomplicated, urinary tract infections: A prospective, controlled study.
High relevance for UTI treatment
We examined the effects of a specific supplement, combining Lactobacillus strains with proanthocyanidin-rich extracts from cranberry and cinnamon, on recurrent urinary tract infections (UTIs) in women.
In our controlled study with 80 participants over six months, we compared those taking the supplement to a non-supplemented group.
The results were striking: 64.9% of women on the supplement didn't experience any cystitis episodes, versus just 31.6% of those without. Additionally, the supplement significantly improved symptom severity and quality of life.
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Probiotics effectively prevent UTIsEffectiveness of Prophylactic Oral and/or Vaginal Probiotic Supplementation in the Prevention of Recurrent Urinary Tract Infections: A Randomized, Double-Blind, Placebo-Controlled Trial.
High relevance for UTI prevention
We evaluated how probiotics could help prevent recurrent urinary tract infections (UTIs) in premenopausal women. In our study, 174 women were randomly assigned to different treatment groups, including a placebo and various probiotic combinations over four months. After tracking symptoms for a year, we found that using vaginal probiotics, alone or combined with oral ones, effectively reduced episodes of symptomatic UTIs. This suggests probiotics may be a promising non-antibiotic approach to managing recurrent UTIs.
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We examined how the GAI98322 strain of Lactobacillus crispatus can help in preventing recurrent cystitis. Through tests on its cell-free culture supernatant, we found that it effectively reduces the growth and biofilm formation of various harmful bacteria, including E. coli and Pseudomonas aeruginosa.
This action is facilitated by specific factors, which work independently of traditional antibiotics. While our findings highlight the potential of Lactobacillus in managing recurrent infections, further studies are essential to confirm its effectiveness in clinical settings.
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