' 
SCIENTIFIC SCORE
Possibly Effective
Based on 10 Researches
7.7
USERS' SCORE
Good
Based on 2 Reviews
8
Supplement Facts
Serving Size: 1 Capsule
Amount Per Serving
%DV
Turmeric ExtractCurcuma longa (Rhizome)(95% [475 mg] Total Curcuminoids)
500 mg
†
Top Medical Research Studies
2
Curcumin shows no allergy test effects
Curcumin does not significantly affect immediate skin tests.
Direct assessment of curcumin's impact
We focused on how turmeric, specifically curcumin, might influence allergies. Our study involved 34 participants who were allergic to certain antigens. To assess the effect of curcumin, we randomly assigned participants to receive either curcumin or a placebo for one week, all while keeping the study double-blind to eliminate bias.
After this week, we conducted skin-prick tests to measure reactions before and after the treatment. We compared the size of the skin test reactions, or wheals and flares, to see if there were any significant changes.
The results were clear: curcumin did not show a statistically significant impact on the size of these reactions. Although earlier studies suggested that curcumin may help reduce allergic symptoms, our findings indicate that it does not change the immediate response measured through skin tests. Thus, there's no need to stop using curcumin before allergy testing since it doesn't interfere with the results.
After this week, we conducted skin-prick tests to measure reactions before and after the treatment. We compared the size of the skin test reactions, or wheals and flares, to see if there were any significant changes.
The results were clear: curcumin did not show a statistically significant impact on the size of these reactions. Although earlier studies suggested that curcumin may help reduce allergic symptoms, our findings indicate that it does not change the immediate response measured through skin tests. Thus, there's no need to stop using curcumin before allergy testing since it doesn't interfere with the results.
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9
Turmeric extract alleviates atopic dermatitis
Protective effect of Curcuma longa L. leaves and pseudostems extract against 1-chloro-2,4-dinitrobenzene-induced atopic dermatitis in BALB/c mice.
Directly investigates allergy treatment
We aimed to understand how turmeric, particularly its leaves and pseudostems, impacts allergies, specifically atopic dermatitis (AD). In our study, we utilized the BALB/c mouse model to mimic the symptoms of AD by applying a chemical called DNCB to the skin.
After introducing the symptoms, we divided the mice into groups, with some receiving daily doses of turmeric extract for three weeks. Throughout this time, we carefully observed various factors, such as skin condition, moisture loss, scratching behavior, and overall health indicators, including serum levels of antibodies and immune responses.
Our findings revealed that the turmeric extract significantly alleviated the AD-like symptoms in the treated mice. The skin's severity scores improved, and we noticed decreased, itchy scratching and moisture loss. Moreover, there were lower serum immunoglobulin levels and less inflammation compared to untreated mice. This highlights turmeric's potential as a natural remedy for managing allergic reactions related to atopic dermatitis.
After introducing the symptoms, we divided the mice into groups, with some receiving daily doses of turmeric extract for three weeks. Throughout this time, we carefully observed various factors, such as skin condition, moisture loss, scratching behavior, and overall health indicators, including serum levels of antibodies and immune responses.
Our findings revealed that the turmeric extract significantly alleviated the AD-like symptoms in the treated mice. The skin's severity scores improved, and we noticed decreased, itchy scratching and moisture loss. Moreover, there were lower serum immunoglobulin levels and less inflammation compared to untreated mice. This highlights turmeric's potential as a natural remedy for managing allergic reactions related to atopic dermatitis.
Read More
9
Turmeric shows promise for allergies
Leaves and pseudostems extract of Curcuma longa attenuates immunoglobulin E/bovine serum albumin-stimulated bone marrow-derived cultured mast cell activation and passive cutaneous anaphylaxis in BALB/c mice.
Directly addresses turmeric allergy effects
This study examines the potential of turmeric leaves and pseudostems extract to ease allergic responses, particularly in how it affects mast cells. We analyzed its impact on specific immune reactions triggered by allergens, focusing on the release of various chemicals known to play roles in allergy symptoms.
By assessing mast cell degranulation, we observed that the extract significantly reduced the release of important mediators like histamine. This suggests that turmeric might help control allergic reactions at the cellular level.
Furthermore, in our exploration, we noticed that turmeric extract downregulated key signaling pathways involved in allergic responses. This helped to diminish the release of allergy-related cytokines and chemokines.
Additionally, in an in vivo setting, we tested turmeric’s effect on mice experiencing IgE-mediated passive cutaneous anaphylaxis, finding it successfully attenuated the allergic reactions. Overall, these findings indicate turmeric's potential as a powerful ally in managing allergies.
By assessing mast cell degranulation, we observed that the extract significantly reduced the release of important mediators like histamine. This suggests that turmeric might help control allergic reactions at the cellular level.
Furthermore, in our exploration, we noticed that turmeric extract downregulated key signaling pathways involved in allergic responses. This helped to diminish the release of allergy-related cytokines and chemokines.
Additionally, in an in vivo setting, we tested turmeric’s effect on mice experiencing IgE-mediated passive cutaneous anaphylaxis, finding it successfully attenuated the allergic reactions. Overall, these findings indicate turmeric's potential as a powerful ally in managing allergies.
Read More
Most Useful Reviews
6.8
Slight improvement
When allergy symptoms arise, I give this to my child when they have a runny nose. I believe it helps alleviate the issue somewhat.
Read More
3.5
No improvement
I have allergies and rosacea, so I hoped this would enhance my skin, but it didn't have any effect.
Read More
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 10 Researches
7.7
9
Turmeric extract alleviates atopic dermatitis
Protective effect of Curcuma longa L. leaves and pseudostems extract against 1-chloro-2,4-dinitrobenzene-induced atopic dermatitis in BALB/c mice.
Directly investigates allergy treatment
We aimed to understand how turmeric, particularly its leaves and pseudostems, impacts allergies, specifically atopic dermatitis (AD). In our study, we utilized the BALB/c mouse model to mimic the symptoms of AD by applying a chemical called DNCB to the skin.
After introducing the symptoms, we divided the mice into groups, with some receiving daily doses of turmeric extract for three weeks. Throughout this time, we carefully observed various factors, such as skin condition, moisture loss, scratching behavior, and overall health indicators, including serum levels of antibodies and immune responses.
Our findings revealed that the turmeric extract significantly alleviated the AD-like symptoms in the treated mice. The skin's severity scores improved, and we noticed decreased, itchy scratching and moisture loss. Moreover, there were lower serum immunoglobulin levels and less inflammation compared to untreated mice. This highlights turmeric's potential as a natural remedy for managing allergic reactions related to atopic dermatitis.
After introducing the symptoms, we divided the mice into groups, with some receiving daily doses of turmeric extract for three weeks. Throughout this time, we carefully observed various factors, such as skin condition, moisture loss, scratching behavior, and overall health indicators, including serum levels of antibodies and immune responses.
Our findings revealed that the turmeric extract significantly alleviated the AD-like symptoms in the treated mice. The skin's severity scores improved, and we noticed decreased, itchy scratching and moisture loss. Moreover, there were lower serum immunoglobulin levels and less inflammation compared to untreated mice. This highlights turmeric's potential as a natural remedy for managing allergic reactions related to atopic dermatitis.
Read More
9
Turmeric extract alleviates asthma inflammation
Turmeric extract alleviates airway inflammation via oxidative stress-driven MAPKs/MMPs pathway.
Direct connection to asthma treatment
We explored the effects of turmeric extract (CLE) on airway inflammation, particularly in relation to asthma and allergies. Using an asthmatic mouse model that was sensitized with ovalbumin (OVA), we observed how different doses of CLE (100 or 300 mg/kg/day) impacted inflammation. Dexamethasone was used as a positive control to compare its effects.
Our findings revealed that both doses of CLE significantly reduced eosinophil counts, cytokine levels, and immunoglobulin-E levels associated with allergic responses. This suggests that turmeric extract has a promising role in managing allergy-related symptoms. Additionally, we noted that CLE effectively decreased oxidative stress and inflammation in lung tissues.
On a cellular level, when we treated human airway epithelial cells (A549) with CLE, we saw reductions in proinflammatory cytokines and a decrease in the activity of certain proteins that contribute to inflammation, specifically matrix metalloproteinases (MMPs). Curcumin, a compound found in turmeric, also demonstrated similar anti-inflammatory effects at lower concentrations.
Overall, our research indicates that turmeric extract could be a beneficial treatment option for individuals struggling with asthma and related allergies, thanks to its ability to target inflammation on multiple fronts.
Our findings revealed that both doses of CLE significantly reduced eosinophil counts, cytokine levels, and immunoglobulin-E levels associated with allergic responses. This suggests that turmeric extract has a promising role in managing allergy-related symptoms. Additionally, we noted that CLE effectively decreased oxidative stress and inflammation in lung tissues.
On a cellular level, when we treated human airway epithelial cells (A549) with CLE, we saw reductions in proinflammatory cytokines and a decrease in the activity of certain proteins that contribute to inflammation, specifically matrix metalloproteinases (MMPs). Curcumin, a compound found in turmeric, also demonstrated similar anti-inflammatory effects at lower concentrations.
Overall, our research indicates that turmeric extract could be a beneficial treatment option for individuals struggling with asthma and related allergies, thanks to its ability to target inflammation on multiple fronts.
Read More
9
Curcumin shows promise for allergies
Development of fast-dissolving sublingual nanofibers containing allergen and curcumin for immune response modulation in a mouse model of allergic rhinitis.
Addresses immune modulation in allergies
We focused on how curcumin, a natural compound found in turmeric, could help treat allergic rhinitis when combined with an allergen. To investigate this, we utilized nanofibers infused with curcumin and ovalbumin—an allergen commonly associated with allergies. We prepared these nanofibers using electrospinning and then tested their effects in a mouse model of allergic rhinitis.
The results were promising! When we administered sublingual immunotherapy (SLIT) using these nanofibers, we observed a noteworthy reduction in serum IgE levels, which are often elevated in allergic reactions. Specifically, the formulation containing 2.5 µg of curcumin per mouse showed a significant decrease in IL-4—a marker associated with allergic responses—while levels of INF-γ, which helps modulate immune responses, increased.
Additionally, the analysis of nasal lavage fluid revealed fewer allergic cells and eosinophils in the treated groups. Histological examinations showed that the nasal tissue health approached normal, with less inflammation and cellular infiltration. Overall, these findings suggest that the combination of curcumin and the allergen in our nanofiber treatments could be a promising route for improving allergic rhinitis management.
The results were promising! When we administered sublingual immunotherapy (SLIT) using these nanofibers, we observed a noteworthy reduction in serum IgE levels, which are often elevated in allergic reactions. Specifically, the formulation containing 2.5 µg of curcumin per mouse showed a significant decrease in IL-4—a marker associated with allergic responses—while levels of INF-γ, which helps modulate immune responses, increased.
Additionally, the analysis of nasal lavage fluid revealed fewer allergic cells and eosinophils in the treated groups. Histological examinations showed that the nasal tissue health approached normal, with less inflammation and cellular infiltration. Overall, these findings suggest that the combination of curcumin and the allergen in our nanofiber treatments could be a promising route for improving allergic rhinitis management.
Read More
9
Turmeric shows promise for allergies
Leaves and pseudostems extract of Curcuma longa attenuates immunoglobulin E/bovine serum albumin-stimulated bone marrow-derived cultured mast cell activation and passive cutaneous anaphylaxis in BALB/c mice.
Directly addresses turmeric allergy effects
This study examines the potential of turmeric leaves and pseudostems extract to ease allergic responses, particularly in how it affects mast cells. We analyzed its impact on specific immune reactions triggered by allergens, focusing on the release of various chemicals known to play roles in allergy symptoms.
By assessing mast cell degranulation, we observed that the extract significantly reduced the release of important mediators like histamine. This suggests that turmeric might help control allergic reactions at the cellular level.
Furthermore, in our exploration, we noticed that turmeric extract downregulated key signaling pathways involved in allergic responses. This helped to diminish the release of allergy-related cytokines and chemokines.
Additionally, in an in vivo setting, we tested turmeric’s effect on mice experiencing IgE-mediated passive cutaneous anaphylaxis, finding it successfully attenuated the allergic reactions. Overall, these findings indicate turmeric's potential as a powerful ally in managing allergies.
By assessing mast cell degranulation, we observed that the extract significantly reduced the release of important mediators like histamine. This suggests that turmeric might help control allergic reactions at the cellular level.
Furthermore, in our exploration, we noticed that turmeric extract downregulated key signaling pathways involved in allergic responses. This helped to diminish the release of allergy-related cytokines and chemokines.
Additionally, in an in vivo setting, we tested turmeric’s effect on mice experiencing IgE-mediated passive cutaneous anaphylaxis, finding it successfully attenuated the allergic reactions. Overall, these findings indicate turmeric's potential as a powerful ally in managing allergies.
Read More
9
Turmeric may alleviate allergy symptoms
An antioxidant ameliorates allergic airway inflammation by inhibiting HDAC 1 via HIF-1α/VEGF axis suppression in mice.
Supports curcumin's allergy-reducing potential
We examined how curcumin, a natural compound found in turmeric, affects allergic reactions, particularly in asthma models. In our study, we used mice that were sensitized and exposed to allergens to mimic asthma symptoms, followed by treatment with curcumin and sodium butyrate. This approach helped us investigate whether these compounds could alleviate allergic inflammation by inhibiting histone deacetylase (HDAC1), which plays a role in modifying protein functions related to asthma.
Our findings indicated that curcumin and sodium butyrate significantly reduced markers of inflammation in the airways, specifically by modulating the PI3K/Akt signaling pathway. Notably, we observed that treatment with these compounds led to lower levels of proteins associated with inflammation. Moreover, curcumin and sodium butyrate restored levels of antioxidant proteins that were diminished during asthma.
Overall, these results suggest that curcumin, especially when combined with sodium butyrate, has potential as a treatment for reducing allergic airway inflammation. This could open up new avenues for managing conditions like asthma in the future, highlighting the importance of understanding natural compounds in allergy treatment.
Our findings indicated that curcumin and sodium butyrate significantly reduced markers of inflammation in the airways, specifically by modulating the PI3K/Akt signaling pathway. Notably, we observed that treatment with these compounds led to lower levels of proteins associated with inflammation. Moreover, curcumin and sodium butyrate restored levels of antioxidant proteins that were diminished during asthma.
Overall, these results suggest that curcumin, especially when combined with sodium butyrate, has potential as a treatment for reducing allergic airway inflammation. This could open up new avenues for managing conditions like asthma in the future, highlighting the importance of understanding natural compounds in allergy treatment.
Read More
User Reviews
USERS' SCORE
Good
Based on 2 Reviews
8
6.8
Slight improvement
When allergy symptoms arise, I give this to my child when they have a runny nose. I believe it helps alleviate the issue somewhat.
3.5
No improvement
I have allergies and rosacea, so I hoped this would enhance my skin, but it didn't have any effect.
