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SCIENTIFIC SCORE
Possibly Effective
Based on 8 Researches
7.8
USERS' SCORE
Good
Based on 11 Reviews
8.4
Supplement Facts
Serving Size: 1 Capsule
Amount Per Serving
%DV
Turmeric ExtractCurcuma longa (Rhizome)(95% [475 mg] Total Curcuminoids)
500 mg
†
Top Medical Research Studies
8
Curcumin improves migraine symptoms
Effects of Curcumin Supplementation on Clinical Features and Inflammation, in Migraine Patients: A Double-Blind Controlled, Placebo Randomized Clinical Trial.
Direct assessment of turmeric's effects
We conducted a thoughtful investigation into the effects of curcumin, a natural compound found in turmeric, on migraine sufferers. This study involved 44 women with migraines, who were randomly assigned to receive either 500 mg of curcumin twice a day or a placebo for eight weeks. The team measured various factors, including the severity, duration, and frequency of headaches, as well as specific inflammation markers in the body.
After the eight-week period, we observed noticeable improvements in the group receiving curcumin. Compared to the placebo, participants taking curcumin reported significant reductions in pain severity and headache duration. While there was a slight improvement in how often headaches struck, it didn't reach a level of statistical significance.
Moreover, curcumin supplementation also appeared to lower levels of two important inflammatory markers related to migraines: calcitonin gene-related peptide (CGRP) and interleukin-6 (IL-6). We didn't see any significant changes in body weight or composition between the groups, indicating that the effects were primarily linked to curcumin's properties rather than any other lifestyle changes.
Overall, our findings suggest that curcumin may serve as an effective, natural remedy for managing migraine symptoms, largely due to its anti-inflammatory benefits.
After the eight-week period, we observed noticeable improvements in the group receiving curcumin. Compared to the placebo, participants taking curcumin reported significant reductions in pain severity and headache duration. While there was a slight improvement in how often headaches struck, it didn't reach a level of statistical significance.
Moreover, curcumin supplementation also appeared to lower levels of two important inflammatory markers related to migraines: calcitonin gene-related peptide (CGRP) and interleukin-6 (IL-6). We didn't see any significant changes in body weight or composition between the groups, indicating that the effects were primarily linked to curcumin's properties rather than any other lifestyle changes.
Overall, our findings suggest that curcumin may serve as an effective, natural remedy for managing migraine symptoms, largely due to its anti-inflammatory benefits.
Read More
9
Nano-curcumin reduces migraine symptoms
The effects of nano-curcumin supplementation on adipokines levels in obese and overweight patients with migraine: a double blind clinical trial study.
Direct focus on headache treatment
We explored how nano-curcumin supplementation affects headache symptoms in obese and overweight patients suffering from migraines. In a well-structured clinical trial, we divided forty-four participants into two groups: one received 80 mg of nano-curcumin daily, while the other served as a control group over a two-month period.
At the start and end of the study, we measured the serum levels of various adipokines, including MCP-1, Resistin, and Visfatin, alongside recording the frequency, severity, and duration of headache attacks. The results were intriguing; we found that nano-curcumin significantly reduced MCP-1 serum levels among those supplemented with it. Moreover, patients reported fewer headaches in terms of frequency and severity, making nano-curcumin a promising treatment avenue for migraine management.
However, it’s important to note that while MCP-1 saw meaningful changes, the other adipokines, Resistin and Visfatin, did not show any significant shifts. This suggests that while nano-curcumin may be helpful, it's not universally impactful on all markers. Overall, we believe the study propels the idea that curcumin can be beneficial for people with migraines, although more comprehensive research is needed to fully understand its effects.
At the start and end of the study, we measured the serum levels of various adipokines, including MCP-1, Resistin, and Visfatin, alongside recording the frequency, severity, and duration of headache attacks. The results were intriguing; we found that nano-curcumin significantly reduced MCP-1 serum levels among those supplemented with it. Moreover, patients reported fewer headaches in terms of frequency and severity, making nano-curcumin a promising treatment avenue for migraine management.
However, it’s important to note that while MCP-1 saw meaningful changes, the other adipokines, Resistin and Visfatin, did not show any significant shifts. This suggests that while nano-curcumin may be helpful, it's not universally impactful on all markers. Overall, we believe the study propels the idea that curcumin can be beneficial for people with migraines, although more comprehensive research is needed to fully understand its effects.
Read More
7
Phytosomal curcumin beneficial for migraines
The effects of phytosomal curcumin supplementation on clinical symptoms, and inflammatory and oxidative stress biomarkers in patients with migraine: A protocol for a randomized double-blind placebo-controlled trial.
Highly relevant to headache treatment
We conducted a randomized, double-blind, placebo-controlled trial to explore the effects of phytosomal curcumin—a special form of turmeric—on patients suffering from migraines. Our aim was to see if this potent antioxidant and anti-inflammatory treatment could help alleviate the frequency, duration, and intensity of migraine headaches.
In our study, 60 participants were divided into two groups. One received 250 mg of phytosomal curcumin daily, while the other group took a placebo made from maltodextrin for eight weeks. We measured various factors before and after the intervention, including the quality of life, sleep quality, mood, and important biomarkers related to inflammation and oxidative stress.
The results suggest that phytosomal curcumin might effectively reduce neuroinflammation, oxidative stress, and even neurotoxicity. This, in turn, could lead to fewer headaches and improve overall well-being for migraine sufferers. The promising nature of this turmeric formulation, which boasts improved absorption and the ability to cross the blood-brain barrier, adds to the excitement around its potential benefits in managing migraines.
In our study, 60 participants were divided into two groups. One received 250 mg of phytosomal curcumin daily, while the other group took a placebo made from maltodextrin for eight weeks. We measured various factors before and after the intervention, including the quality of life, sleep quality, mood, and important biomarkers related to inflammation and oxidative stress.
The results suggest that phytosomal curcumin might effectively reduce neuroinflammation, oxidative stress, and even neurotoxicity. This, in turn, could lead to fewer headaches and improve overall well-being for migraine sufferers. The promising nature of this turmeric formulation, which boasts improved absorption and the ability to cross the blood-brain barrier, adds to the excitement around its potential benefits in managing migraines.
Read More
Most Useful Reviews
9.5
Relieves detox headaches
This product effectively alleviates my detox headaches. I found that other supplements caused mild headaches, but this one does not have any side effects.
Read More
9.5
Wine enjoyment
I was unsure if this product worked for me until I tested it with red wine. I used to get a headache every time I drank it, which was frustrating. Now, I simply take one capsule beforehand and enjoy my wine—no headache. It's amazing!
Read More
8.8
Significant health improvement
These work, and this brand is the real deal! I take these for liver health due to frequent Excedrin use for chronic headaches. My liver tests have pleased my doctors. They have also helped my husband with his liver and pancreas issues, almost eliminating his pain. If he forgets to take them, he notices it immediately.
Read More
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 8 Researches
7.8
9
Nano-curcumin reduces migraine symptoms
The effects of nano-curcumin supplementation on adipokines levels in obese and overweight patients with migraine: a double blind clinical trial study.
Direct focus on headache treatment
We explored how nano-curcumin supplementation affects headache symptoms in obese and overweight patients suffering from migraines. In a well-structured clinical trial, we divided forty-four participants into two groups: one received 80 mg of nano-curcumin daily, while the other served as a control group over a two-month period.
At the start and end of the study, we measured the serum levels of various adipokines, including MCP-1, Resistin, and Visfatin, alongside recording the frequency, severity, and duration of headache attacks. The results were intriguing; we found that nano-curcumin significantly reduced MCP-1 serum levels among those supplemented with it. Moreover, patients reported fewer headaches in terms of frequency and severity, making nano-curcumin a promising treatment avenue for migraine management.
However, it’s important to note that while MCP-1 saw meaningful changes, the other adipokines, Resistin and Visfatin, did not show any significant shifts. This suggests that while nano-curcumin may be helpful, it's not universally impactful on all markers. Overall, we believe the study propels the idea that curcumin can be beneficial for people with migraines, although more comprehensive research is needed to fully understand its effects.
At the start and end of the study, we measured the serum levels of various adipokines, including MCP-1, Resistin, and Visfatin, alongside recording the frequency, severity, and duration of headache attacks. The results were intriguing; we found that nano-curcumin significantly reduced MCP-1 serum levels among those supplemented with it. Moreover, patients reported fewer headaches in terms of frequency and severity, making nano-curcumin a promising treatment avenue for migraine management.
However, it’s important to note that while MCP-1 saw meaningful changes, the other adipokines, Resistin and Visfatin, did not show any significant shifts. This suggests that while nano-curcumin may be helpful, it's not universally impactful on all markers. Overall, we believe the study propels the idea that curcumin can be beneficial for people with migraines, although more comprehensive research is needed to fully understand its effects.
Read More
9
Combined therapy shows migraine relief
The synergistic effects of nano-curcumin and coenzyme Q10 supplementation in migraine prophylaxis: a randomized, placebo-controlled, double-blind trial.
Evaluates turmeric's additional effectiveness
We studied the effects of nano-curcumin, a compound derived from turmeric, alongside coenzyme Q10 (CoQ10) on individuals suffering from migraines. This double-blind, placebo-controlled trial included 100 participants who experienced episodic migraines, carefully monitored over an 8-week period. They were divided into four groups, with one group receiving the combination of nano-curcumin and CoQ10, while others received either supplement alone or a placebo.
Our findings were promising, indicating that participants who took both nano-curcumin and CoQ10 reported significant improvements in migraine frequency, severity, and duration. They also noticed better quality of life scores on specific migraine questionnaires compared to the other groups. Importantly, no side effects were reported, adding further value to this combination treatment.
Through this study, we suggest that using nano-curcumin with CoQ10 may provide a synergistic effect, making it a potential new strategy for managing migraines effectively. However, the design of the study limits our ability to evaluate the isolated effects of turmeric alone on headache relief.
Our findings were promising, indicating that participants who took both nano-curcumin and CoQ10 reported significant improvements in migraine frequency, severity, and duration. They also noticed better quality of life scores on specific migraine questionnaires compared to the other groups. Importantly, no side effects were reported, adding further value to this combination treatment.
Through this study, we suggest that using nano-curcumin with CoQ10 may provide a synergistic effect, making it a potential new strategy for managing migraines effectively. However, the design of the study limits our ability to evaluate the isolated effects of turmeric alone on headache relief.
Read More
8
Curcumin improves migraine symptoms
Effects of Curcumin Supplementation on Clinical Features and Inflammation, in Migraine Patients: A Double-Blind Controlled, Placebo Randomized Clinical Trial.
Direct assessment of turmeric's effects
We conducted a thoughtful investigation into the effects of curcumin, a natural compound found in turmeric, on migraine sufferers. This study involved 44 women with migraines, who were randomly assigned to receive either 500 mg of curcumin twice a day or a placebo for eight weeks. The team measured various factors, including the severity, duration, and frequency of headaches, as well as specific inflammation markers in the body.
After the eight-week period, we observed noticeable improvements in the group receiving curcumin. Compared to the placebo, participants taking curcumin reported significant reductions in pain severity and headache duration. While there was a slight improvement in how often headaches struck, it didn't reach a level of statistical significance.
Moreover, curcumin supplementation also appeared to lower levels of two important inflammatory markers related to migraines: calcitonin gene-related peptide (CGRP) and interleukin-6 (IL-6). We didn't see any significant changes in body weight or composition between the groups, indicating that the effects were primarily linked to curcumin's properties rather than any other lifestyle changes.
Overall, our findings suggest that curcumin may serve as an effective, natural remedy for managing migraine symptoms, largely due to its anti-inflammatory benefits.
After the eight-week period, we observed noticeable improvements in the group receiving curcumin. Compared to the placebo, participants taking curcumin reported significant reductions in pain severity and headache duration. While there was a slight improvement in how often headaches struck, it didn't reach a level of statistical significance.
Moreover, curcumin supplementation also appeared to lower levels of two important inflammatory markers related to migraines: calcitonin gene-related peptide (CGRP) and interleukin-6 (IL-6). We didn't see any significant changes in body weight or composition between the groups, indicating that the effects were primarily linked to curcumin's properties rather than any other lifestyle changes.
Overall, our findings suggest that curcumin may serve as an effective, natural remedy for managing migraine symptoms, largely due to its anti-inflammatory benefits.
Read More
8
Curcumin potentially aids migraine relief
The synergistic effects of ω-3 fatty acids and nano-curcumin supplementation on tumor necrosis factor (TNF)-α gene expression and serum level in migraine patients.
Curcumin's effectiveness uncertain
We aimed to understand whether turmeric, specifically its active component curcumin, could help alleviate headaches associated with migraines. Our research involved a clinical trial with 74 patients who were experiencing episodic migraines. They were divided into four groups: some took omega-3 fatty acids, others took nano-curcumin, and some received a combination of both, while one group was given a placebo.
After two months, we observed that the group receiving both omega-3s and nano-curcumin had a significant reduction in the gene expression of tumor necrosis factor (TNF)-α, which is linked to migraine symptoms. Interestingly, the combination group also showed a noticeable drop in serum TNF-α levels, pointing to a potential synergistic effect.
However, those taking either omega-3s or curcumin alone did not experience the same benefits, indicating that turmeric's effects on headaches may be enhanced when paired with omega-3 fatty acids. Overall, we found this combination to significantly reduce headache frequency, presenting a promising new approach to migraine management.
After two months, we observed that the group receiving both omega-3s and nano-curcumin had a significant reduction in the gene expression of tumor necrosis factor (TNF)-α, which is linked to migraine symptoms. Interestingly, the combination group also showed a noticeable drop in serum TNF-α levels, pointing to a potential synergistic effect.
However, those taking either omega-3s or curcumin alone did not experience the same benefits, indicating that turmeric's effects on headaches may be enhanced when paired with omega-3 fatty acids. Overall, we found this combination to significantly reduce headache frequency, presenting a promising new approach to migraine management.
Read More
7
Phytosomal curcumin beneficial for migraines
The effects of phytosomal curcumin supplementation on clinical symptoms, and inflammatory and oxidative stress biomarkers in patients with migraine: A protocol for a randomized double-blind placebo-controlled trial.
Highly relevant to headache treatment
We conducted a randomized, double-blind, placebo-controlled trial to explore the effects of phytosomal curcumin—a special form of turmeric—on patients suffering from migraines. Our aim was to see if this potent antioxidant and anti-inflammatory treatment could help alleviate the frequency, duration, and intensity of migraine headaches.
In our study, 60 participants were divided into two groups. One received 250 mg of phytosomal curcumin daily, while the other group took a placebo made from maltodextrin for eight weeks. We measured various factors before and after the intervention, including the quality of life, sleep quality, mood, and important biomarkers related to inflammation and oxidative stress.
The results suggest that phytosomal curcumin might effectively reduce neuroinflammation, oxidative stress, and even neurotoxicity. This, in turn, could lead to fewer headaches and improve overall well-being for migraine sufferers. The promising nature of this turmeric formulation, which boasts improved absorption and the ability to cross the blood-brain barrier, adds to the excitement around its potential benefits in managing migraines.
In our study, 60 participants were divided into two groups. One received 250 mg of phytosomal curcumin daily, while the other group took a placebo made from maltodextrin for eight weeks. We measured various factors before and after the intervention, including the quality of life, sleep quality, mood, and important biomarkers related to inflammation and oxidative stress.
The results suggest that phytosomal curcumin might effectively reduce neuroinflammation, oxidative stress, and even neurotoxicity. This, in turn, could lead to fewer headaches and improve overall well-being for migraine sufferers. The promising nature of this turmeric formulation, which boasts improved absorption and the ability to cross the blood-brain barrier, adds to the excitement around its potential benefits in managing migraines.
Read More
User Reviews
USERS' SCORE
Good
Based on 11 Reviews
8.4
9.5
Relieves detox headaches
This product effectively alleviates my detox headaches. I found that other supplements caused mild headaches, but this one does not have any side effects.
9.5
Good for headaches
Great for relieving headaches.
9.5
Wine enjoyment
I was unsure if this product worked for me until I tested it with red wine. I used to get a headache every time I drank it, which was frustrating. Now, I simply take one capsule beforehand and enjoy my wine—no headache. It's amazing!
8.8
Aids headache pain
Curcumin has proven beneficial for inflammation and pain relief. It’s been effective for my headaches and muscle pain. I always take it with meals and a pinch of black pepper to enhance absorption. It's a vital supplement for my joint pain as well.
8.8
Helps headaches
I purchased this for my mother, and it has notably reduced her joint pain and headaches. I feel reassured that she’s using a natural remedy instead of harsh medications.
