Overview

SCIENTIFIC SCORE
Likely Very Effective
Based on 2 Researches
9
USERS' SCORE
Moderately Good
Based on 4 Reviews
7.9
Supplement Facts
Serving Size: 1 Tablet
Amount Per Serving
%DV
Vitamin B6 (as Pyridoxal-5-Phosphate)
1.5 mg
88%
Folate (400 mcg as (6S)-5-MTHF [from (6S)-5-Methyltetrahydrofolate Glucosamine Salt])
680 mcg DFE‡
170%
Vitamin B12 (as Methylcobalamin)
1,000 mcg
41,667%

Top Medical Research Studies

We explored the effects of riboflavin and biotin deficiencies in premature twins, who initially presented with skin rashes among other severe symptoms. After being diagnosed, one twin began supplementation with these vitamins.

Remarkably, this led to a quick improvement in clinical condition and laboratory findings within days. Though one twin experienced tragic complications resulting in death, the surviving twin went home in stable condition, highlighting the importance of addressing vitamin deficiencies early.
Read More
We looked into how isoniazid exposure affects the risk of developing pellagra—a condition characterized by a distinct rash—among nutritionally vulnerable populations in Malawi. Our case-control study suggested that taking isoniazid significantly increases this risk.

Interestingly, those who discontinued isoniazid and began a treatment regimen of multi-B vitamins experienced noticeable improvement in their rash within just 30 days. This emphasizes the potential benefit of incorporating niacin when administering isoniazid, particularly in populations at risk for nutrition-related issues.
Read More

Most Useful Reviews

9
No allergies experienced
All other vitamin B12 brands caused an allergic rash on my face, but these suited me perfectly.
Read More
9
Rashes significantly decreased
This excellent product has greatly helped me as the rashes on my face have diminished. I feel energised and much better overall.
Read More
8
Significant improvement
The lozenges taste pleasant. I follow the dosage as directed by my endocrinologist. Two years ago, I began experiencing serious facial skin issues, and it took a long time to receive a proper diagnosis. Initially, I was diagnosed with demodecosis, but the prescribed treatments were ineffective. Later, I was correctly diagnosed with rosacea and connective tissue dysplasia. My dermatologist recommended consulting a reputable endocrinologist, noting that taking vitamins as advised would expedite my recovery. Now, I feel significantly better, with the rashes reduced by 80%. I have been taking two lozenges daily under my tongue for the past 1.5 months. Additionally, I have been prescribed several other medications, ordered from iHerb, where prices are much lower than in Moscow pharmacies!
Read More

Medical Researches

SCIENTIFIC SCORE
Likely Very Effective
Based on 2 Researches
9
  • All Researches
We explored the effects of riboflavin and biotin deficiencies in premature twins, who initially presented with skin rashes among other severe symptoms. After being diagnosed, one twin began supplementation with these vitamins.

Remarkably, this led to a quick improvement in clinical condition and laboratory findings within days. Though one twin experienced tragic complications resulting in death, the surviving twin went home in stable condition, highlighting the importance of addressing vitamin deficiencies early.
Read More
We looked into how isoniazid exposure affects the risk of developing pellagra—a condition characterized by a distinct rash—among nutritionally vulnerable populations in Malawi. Our case-control study suggested that taking isoniazid significantly increases this risk.

Interestingly, those who discontinued isoniazid and began a treatment regimen of multi-B vitamins experienced noticeable improvement in their rash within just 30 days. This emphasizes the potential benefit of incorporating niacin when administering isoniazid, particularly in populations at risk for nutrition-related issues.
Read More

User Reviews

USERS' SCORE
Moderately Good
Based on 4 Reviews
7.9
  • All Reviews
  • Positive Reviews
  • Negative Reviews
9
No allergies experienced
All other vitamin B12 brands caused an allergic rash on my face, but these suited me perfectly.
Read More
9
Rashes significantly decreased
This excellent product has greatly helped me as the rashes on my face have diminished. I feel energised and much better overall.
Read More
8
Significant improvement
The lozenges taste pleasant. I follow the dosage as directed by my endocrinologist. Two years ago, I began experiencing serious facial skin issues, and it took a long time to receive a proper diagnosis. Initially, I was diagnosed with demodecosis, but the prescribed treatments were ineffective. Later, I was correctly diagnosed with rosacea and connective tissue dysplasia. My dermatologist recommended consulting a reputable endocrinologist, noting that taking vitamins as advised would expedite my recovery. Now, I feel significantly better, with the rashes reduced by 80%. I have been taking two lozenges daily under my tongue for the past 1.5 months. Additionally, I have been prescribed several other medications, ordered from iHerb, where prices are much lower than in Moscow pharmacies!
Read More
0
Allergic reaction noted
I recommend these vitamins, although they caused me allergic rashes. I gave them to my mother, and they were suitable for her.
Read More

Frequently Asked Questions

8
Significant improvement
The lozenges taste pleasant. I follow the dosage as directed by my endocrinologist. Two years ago, I began experiencing serious facial skin issues, and it took a long time to receive a proper diagnosis. Initially, I was diagnosed with demodecosis, but the prescribed treatments were ineffective. Later, I was correctly diagnosed with rosacea and connective tissue dysplasia. My dermatologist recommended consulting a reputable endocrinologist, noting that taking vitamins as advised would expedite my recovery. Now, I feel significantly better, with the rashes reduced by 80%. I have been taking two lozenges daily under my tongue for the past 1.5 months. Additionally, I have been prescribed several other medications, ordered from iHerb, where prices are much lower than in Moscow pharmacies!
9
Rashes significantly decreased
This excellent product has greatly helped me as the rashes on my face have diminished. I feel energised and much better overall.
9
No allergies experienced
All other vitamin B12 brands caused an allergic rash on my face, but these suited me perfectly.
0
Allergic reaction noted
I recommend these vitamins, although they caused me allergic rashes. I gave them to my mother, and they were suitable for her.
We explored the effects of riboflavin and biotin deficiencies in premature twins, who initially presented with skin rashes among other severe symptoms. After being diagnosed, one twin began supplementation with these vitamins.

Remarkably, this led to a quick improvement in clinical condition and laboratory findings within days. Though one twin experienced tragic complications resulting in death, the surviving twin went home in stable condition, highlighting the importance of addressing vitamin deficiencies early.
We looked into how isoniazid exposure affects the risk of developing pellagra—a condition characterized by a distinct rash—among nutritionally vulnerable populations in Malawi. Our case-control study suggested that taking isoniazid significantly increases this risk.

Interestingly, those who discontinued isoniazid and began a treatment regimen of multi-B vitamins experienced noticeable improvement in their rash within just 30 days. This emphasizes the potential benefit of incorporating niacin when administering isoniazid, particularly in populations at risk for nutrition-related issues.

References

  1. Adie MA, Martes Gomez M, Yom J, Durand M, Wertheimer F, et al. Twin Premature Infants With Riboflavin and Biotin Deficiency Presenting With Refractory Lactic Acidosis, Rash, and Multiorgan Failure During Prolonged Parenteral Nutrition. J Investig Med High Impact Case Rep. 2023;11:23247096231168111. doi:10.1177/23247096231168111
  2. Nabity SA, Mponda K, Gutreuter S, Surie D, Zimba SB, et al. Isoniazid-associated pellagra during mass scale-up of tuberculosis preventive therapy: a case-control study. Lancet Glob Health. 2022;10:e705. doi:10.1016/S2214-109X(22)00096-1
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