Overview

SCIENTIFIC SCORE
Possibly Effective
Based on 1 Research
7
USERS' SCORE
Good
Based on 14 Reviews
8.1
Supplement Facts
Serving Size: 1 Capsule
Amount Per Serving
%DV
MethylSulfonylMethane (MSM)
1,000 mg

Top Medical Research Studies

We analyzed data from 35 patients with KCNA2 IgG autoantibodies linked to various neuropsychiatric issues, including cognitive impairment and seizures. These autoantibodies were notably present in cerebrospinal fluid in some patients and showed different subclasses in serum.

Notably, four patients saw significant improvement with early immunotherapy, particularly those with autoimmune encephalitis. The findings suggest that KCNA2 autoimmunity is varied, indicating the need for more research to clarify its role and therapeutic approaches.
Read More

Most Useful Reviews

9
Reduced pain
8 people found this helpful
I endure cartilage tissue degeneration, experiencing severe joint pain from spinal hernias and protrusions. MSM has been tremendously helpful, enabling me to go without a corset, as directed by my doctors. I rarely rely on painkillers anymore, and I highly recommend this natural remedy to those in similar circumstances.
Read More
9
Effective pain relief
I used to use my hands a lot, which made my finger joints throb during bad weather. I find it slightly alarming how effective this product is, but I encourage everyone to order quickly.
Read More
9
Joint resilience
23 people found this helpful
I've started using MSM combined with collagen and vitamin C, and the results have been remarkable. My joint conditions significantly improved, allowing me to handle heavier loads without discomfort and reducing the frequency of colds. Previously, I was susceptible to drafts and infections; however, I've tested my resilience by sitting in winter, and it proved effective. The convenience of capsules makes it easier for those who dislike the powder's taste.
Read More

Medical Researches

SCIENTIFIC SCORE
Possibly Effective
Based on 1 Research
7
  • All Researches
We analyzed data from 35 patients with KCNA2 IgG autoantibodies linked to various neuropsychiatric issues, including cognitive impairment and seizures. These autoantibodies were notably present in cerebrospinal fluid in some patients and showed different subclasses in serum.

Notably, four patients saw significant improvement with early immunotherapy, particularly those with autoimmune encephalitis. The findings suggest that KCNA2 autoimmunity is varied, indicating the need for more research to clarify its role and therapeutic approaches.
Read More

User Reviews

USERS' SCORE
Good
Based on 14 Reviews
8.1
  • All Reviews
  • Positive Reviews
  • Negative Reviews
9
Reduced pain
8 people found this helpful
I endure cartilage tissue degeneration, experiencing severe joint pain from spinal hernias and protrusions. MSM has been tremendously helpful, enabling me to go without a corset, as directed by my doctors. I rarely rely on painkillers anymore, and I highly recommend this natural remedy to those in similar circumstances.
Read More
9
Effective pain relief
I used to use my hands a lot, which made my finger joints throb during bad weather. I find it slightly alarming how effective this product is, but I encourage everyone to order quickly.
Read More
9
Joint resilience
23 people found this helpful
I've started using MSM combined with collagen and vitamin C, and the results have been remarkable. My joint conditions significantly improved, allowing me to handle heavier loads without discomfort and reducing the frequency of colds. Previously, I was susceptible to drafts and infections; however, I've tested my resilience by sitting in winter, and it proved effective. The convenience of capsules makes it easier for those who dislike the powder's taste.
Read More
7.5
Sulfur benefits
8 people found this helpful
I am a loyal customer of the JARROW brand. I’ve recently been taking their sulfur supplement combined with glucosamine and chondroitin, which is vital for joint support and inflammation relief. I regret not having discovered its benefits earlier. Additionally, sulfur greatly assists with acne-prone skin. With 200 capsules available, this quantity lasts sufficiently long and is often on discount.
Read More
6
Reliable supplement
2 people found this helpful
This is the remedy that led me to start ordering from iHerb! It's my constant companion—trustworthy and wonderful. It seems to support joint health, and although the effects are subtle, I definitely feel the benefits. Highly recommend!
Read More

Frequently Asked Questions

9
Joint resilience
23 people found this helpful
I've started using MSM combined with collagen and vitamin C, and the results have been remarkable. My joint conditions significantly improved, allowing me to handle heavier loads without discomfort and reducing the frequency of colds. Previously, I was susceptible to drafts and infections; however, I've tested my resilience by sitting in winter, and it proved effective. The convenience of capsules makes it easier for those who dislike the powder's taste.
6
Reliable supplement
2 people found this helpful
This is the remedy that led me to start ordering from iHerb! It's my constant companion—trustworthy and wonderful. It seems to support joint health, and although the effects are subtle, I definitely feel the benefits. Highly recommend!
6
Affordable quality
2 people found this helpful
This MSM nutritional supplement is the best in terms of price and quantity. Jarrow, a leading supplement brand, offers a quality product at a lower price compared to domestic options. I regularly order it for my parents, who suffer from knee joint issues, and they claim it’s more effective when taken with vitamin C. While some attribute improvements to placebo, I firmly believe there’s a genuine enhancement effect when consistently used.
6
Minimal effect noted
I ordered this dietary supplement based on its praise for joint support. While the quality and ingredients are excellent, I struggled to maintain consistency with it. The packaging is sealed and suitable for those aged 18+. Unfortunately, the benefits were minimal, likely due to my lack of commitment. A proper diet and calcium intake are crucial as well.
9
Reduced pain
8 people found this helpful
I endure cartilage tissue degeneration, experiencing severe joint pain from spinal hernias and protrusions. MSM has been tremendously helpful, enabling me to go without a corset, as directed by my doctors. I rarely rely on painkillers anymore, and I highly recommend this natural remedy to those in similar circumstances.
9
Improved joint mobility
1 people found this helpful
An excellent preparation of methylsulfonylmethane. I have tried various brands of MSM, and this one is very effective. The convenience of having 200 capsules per package is great, especially as I need 2 per day. For those suffering from serious issues with the ligamentous apparatus, I suggest increasing to 3 capsules daily. My joints have stopped cracking, and I feel more mobile. Additionally, my vision appears to have improved, and my heels are no longer dry. Though my problems occasionally return, I can always reorder this product. Thank you to those who recommend it. Wishing everyone good health!
7.5
Better knee pain
I wish the size was a bit smaller. My parents mentioned experiencing joint pain with age, so I ordered this product thinking it would help. After using it, I noticed my parents’ knee joint pain seems to have improved. However, they dislike the large size of the capsules!
7.5
Sulfur benefits
8 people found this helpful
I am a loyal customer of the JARROW brand. I’ve recently been taking their sulfur supplement combined with glucosamine and chondroitin, which is vital for joint support and inflammation relief. I regret not having discovered its benefits earlier. Additionally, sulfur greatly assists with acne-prone skin. With 200 capsules available, this quantity lasts sufficiently long and is often on discount.
7.5
Supports joint health
3 people found this helpful
Great! I really love and trust this JARROW brand and often order their products. I find it very helpful for supporting joints and relieving inflammation. I regret not having taken sulfur earlier, as I was unaware of its benefits. Sulfur is also advantageous for skin prone to acne.
We analyzed data from 35 patients with KCNA2 IgG autoantibodies linked to various neuropsychiatric issues, including cognitive impairment and seizures. These autoantibodies were notably present in cerebrospinal fluid in some patients and showed different subclasses in serum.

Notably, four patients saw significant improvement with early immunotherapy, particularly those with autoimmune encephalitis. The findings suggest that KCNA2 autoimmunity is varied, indicating the need for more research to clarify its role and therapeutic approaches.

References

  1. Arlt FA, Miske R, Machule ML, Broegger Christensen P, Mindorf S, et al. KCNA2 IgG autoimmunity in neuropsychiatric diseases. Brain Behav Immun. 2024;117:399. doi:10.1016/j.bbi.2024.01.220
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