Overview
SCIENTIFIC SCORE
Moderately Effective
Based on 9 Researches
8.2
USERS' SCORE
Moderately Good
Based on 17 Reviews
7.6
Supplement Facts
Serving Size: 1 Capsule
Amount Per Serving
%DV
Zinc (as Zinc L-Methionine Sulfate)
15 mg
136%
Copper (as Gluconate)
1 mg
111%
Top Medical Research Studies
9
We conducted a double-blind, placebo-controlled clinical trial to explore the effectiveness of a zinc oxide/glycine cream in treating cold sores caused by facial and circumoral herpes. By dividing 46 participants into two groups, one receiving the zinc treatment and the other a placebo, we aimed to measure how this formulation affected the duration and severity of cold sore symptoms.
Our results were quite promising! Participants who began using the zinc oxide/glycine cream within the first 24 hours of noticing symptoms experienced cold sore lesions that lasted only an average of 5 days, compared to 6.5 days for those on the placebo. Additionally, we noticed a significant reduction in the overall severity of their symptoms, including blistering, soreness, itching, and tingling.
As for side effects, subjects treated with the zinc cream experienced only minor and reversible issues typical of ionic zinc salt solutions. This indicates that the zinc oxide/glycine cream is not only effective but also safe for treating cold sores, presenting a valuable option for many people seeking relief from this common condition.
Our results were quite promising! Participants who began using the zinc oxide/glycine cream within the first 24 hours of noticing symptoms experienced cold sore lesions that lasted only an average of 5 days, compared to 6.5 days for those on the placebo. Additionally, we noticed a significant reduction in the overall severity of their symptoms, including blistering, soreness, itching, and tingling.
As for side effects, subjects treated with the zinc cream experienced only minor and reversible issues typical of ionic zinc salt solutions. This indicates that the zinc oxide/glycine cream is not only effective but also safe for treating cold sores, presenting a valuable option for many people seeking relief from this common condition.
Read More
9
We conducted a double-blind, placebo-controlled clinical trial to assess the impact of zinc sulfate gel on cold sores, specifically herpes labialis recidivans. In our study, patients treated with zinc sulfate gel, known as Virudermin Gel, experienced significantly reduced symptoms and faster healing compared to those who received just the gel without zinc.
The results were promising; the patients using the zinc gel reported less discomfort, and their sores healed more quickly. Importantly, this treatment showed no significant side effects, making it a safe option for managing cold sores. Additionally, the antiseptic properties of zinc sulfate helped prevent any superinfections, adding another layer of benefit to its use.
Overall, our exploration into zinc’s effectiveness provided valuable insights for both patients and healthcare providers seeking reliable cold sore treatment options. With simple application and proven results, zinc sulfate gel could become a go-to remedy for those frequently struggling with herpes labialis recidivans.
The results were promising; the patients using the zinc gel reported less discomfort, and their sores healed more quickly. Importantly, this treatment showed no significant side effects, making it a safe option for managing cold sores. Additionally, the antiseptic properties of zinc sulfate helped prevent any superinfections, adding another layer of benefit to its use.
Overall, our exploration into zinc’s effectiveness provided valuable insights for both patients and healthcare providers seeking reliable cold sore treatment options. With simple application and proven results, zinc sulfate gel could become a go-to remedy for those frequently struggling with herpes labialis recidivans.
Read More
8
We aimed to understand how zinc might affect the occurrence and duration of cold sores, also known as herpes labialis. In our study, we treated 20 patients, mostly women with an average age of 26.6, who experienced more than six episodes of cold sores each year. They received zinc sulphate at a dose of 22.5 mg twice daily during specific months over a year while we monitored their symptoms for 12 months.
Our results were promising. Patients reported a decrease in the frequency of cold sore episodes, averaging fewer than four instances per year. Moreover, the duration of these episodes was also shortened to around 5.7 days, significantly less than usual for these conditions.
Thus, we can say that systemic zinc sulphate seemed to effectively reduce both the number of cold sore outbreaks and the recovery time. This suggests that zinc might be a beneficial option for individuals who struggle with recurrent cold sores.
Our results were promising. Patients reported a decrease in the frequency of cold sore episodes, averaging fewer than four instances per year. Moreover, the duration of these episodes was also shortened to around 5.7 days, significantly less than usual for these conditions.
Thus, we can say that systemic zinc sulphate seemed to effectively reduce both the number of cold sore outbreaks and the recovery time. This suggests that zinc might be a beneficial option for individuals who struggle with recurrent cold sores.
Read More
Most Useful Reviews
7.5
Improved cold sores
50 people found this helpful
I was initially sceptical about aids for colds, but after experiencing a broken nose and the threat of sinusitis, I began using zinc and vitamin C. I typically suffered from colds for several days, but this time I had just one day of sniffling and a quicker recovery. It seems to have helped with my nose too. However, be cautious as it can cause nausea if taken on an empty stomach.
Read More
9
Strengthened immunity
38 people found this helpful
Each capsule contains 15 mg of zinc and 1 mg of copper, which is perfect for preventing deficiencies and boosting immunity. I've relied on zinc repeatedly at the first signs of a cold, and it's always delivered results. Excellent quality from this manufacturer!
Read More
9
Restored taste
9 people found this helpful
My doctor friend recommended this zinc during our COVID-19 illness, especially after we both lost our sense of taste. I noticed improvement after taking it weekly, while my husband delayed and took longer to recover. It's now my preferred zinc during colds, complements well with monolaurin.
Read More
Medical Researches
SCIENTIFIC SCORE
Moderately Effective
Based on 9 Researches
8.2
- All Researches
9
We explored the connection between zinc levels and recurrent herpes labialis (RHL), commonly known as cold sores. In a study involving 80 individuals, we compared the salivary zinc levels of healthy people with those experiencing RHL during both the acute and convalescent phases.
The findings revealed that patients in the acute phase had significantly lower zinc levels (160.8 ng/ml) compared to when they were recovering (205.7 ng/ml). Both those phases showed lower zinc levels than the healthy individuals' average. This suggests that zinc levels are not just lower when cold sores are present, but also improve after the lesions heal.
Our results indicate that maintaining adequate zinc levels might be beneficial for people suffering from cold sores. Incorporating zinc supplements could play a role in both treating and preventing these uncomfortable outbreaks. We found that increasing serum zinc might help RHL patients, shedding light on a potential supportive treatment strategy for cold sores.
The findings revealed that patients in the acute phase had significantly lower zinc levels (160.8 ng/ml) compared to when they were recovering (205.7 ng/ml). Both those phases showed lower zinc levels than the healthy individuals' average. This suggests that zinc levels are not just lower when cold sores are present, but also improve after the lesions heal.
Our results indicate that maintaining adequate zinc levels might be beneficial for people suffering from cold sores. Incorporating zinc supplements could play a role in both treating and preventing these uncomfortable outbreaks. We found that increasing serum zinc might help RHL patients, shedding light on a potential supportive treatment strategy for cold sores.
Read More
9
We conducted a small pilot study to investigate how a combination of L-lysine, zinc, and herbal ingredients could help treat cold sores caused by the Herpes simplex virus. Our goal was to observe the changes in symptoms such as itching, burning, and soreness among participants over the course of treatment.
Thirty individuals, split evenly between genders, participated in our open-label study. We monitored their symptoms through various methods, including self-reported outcomes, photographs, and daily diaries. By the sixth day of treatment, most participants showed considerable improvement, with some experiencing full resolution of their symptoms.
While we didn't isolate the effect of zinc alone, its inclusion in the treatment mix seems promising. By the end of our study, we found that 87 percent of participants had improved symptomatically, which indicates that the combination treatment may effectively relieve cold sore symptoms. Importantly, no adverse effects were reported during the study, which adds to our understanding of these treatments' safety.
Thirty individuals, split evenly between genders, participated in our open-label study. We monitored their symptoms through various methods, including self-reported outcomes, photographs, and daily diaries. By the sixth day of treatment, most participants showed considerable improvement, with some experiencing full resolution of their symptoms.
While we didn't isolate the effect of zinc alone, its inclusion in the treatment mix seems promising. By the end of our study, we found that 87 percent of participants had improved symptomatically, which indicates that the combination treatment may effectively relieve cold sore symptoms. Importantly, no adverse effects were reported during the study, which adds to our understanding of these treatments' safety.
Read More
9
We conducted a double-blind, placebo-controlled clinical trial to explore the effectiveness of a zinc oxide/glycine cream in treating cold sores caused by facial and circumoral herpes. By dividing 46 participants into two groups, one receiving the zinc treatment and the other a placebo, we aimed to measure how this formulation affected the duration and severity of cold sore symptoms.
Our results were quite promising! Participants who began using the zinc oxide/glycine cream within the first 24 hours of noticing symptoms experienced cold sore lesions that lasted only an average of 5 days, compared to 6.5 days for those on the placebo. Additionally, we noticed a significant reduction in the overall severity of their symptoms, including blistering, soreness, itching, and tingling.
As for side effects, subjects treated with the zinc cream experienced only minor and reversible issues typical of ionic zinc salt solutions. This indicates that the zinc oxide/glycine cream is not only effective but also safe for treating cold sores, presenting a valuable option for many people seeking relief from this common condition.
Our results were quite promising! Participants who began using the zinc oxide/glycine cream within the first 24 hours of noticing symptoms experienced cold sore lesions that lasted only an average of 5 days, compared to 6.5 days for those on the placebo. Additionally, we noticed a significant reduction in the overall severity of their symptoms, including blistering, soreness, itching, and tingling.
As for side effects, subjects treated with the zinc cream experienced only minor and reversible issues typical of ionic zinc salt solutions. This indicates that the zinc oxide/glycine cream is not only effective but also safe for treating cold sores, presenting a valuable option for many people seeking relief from this common condition.
Read More
9
We conducted a double-blind, placebo-controlled clinical trial to assess the impact of zinc sulfate gel on cold sores, specifically herpes labialis recidivans. In our study, patients treated with zinc sulfate gel, known as Virudermin Gel, experienced significantly reduced symptoms and faster healing compared to those who received just the gel without zinc.
The results were promising; the patients using the zinc gel reported less discomfort, and their sores healed more quickly. Importantly, this treatment showed no significant side effects, making it a safe option for managing cold sores. Additionally, the antiseptic properties of zinc sulfate helped prevent any superinfections, adding another layer of benefit to its use.
Overall, our exploration into zinc’s effectiveness provided valuable insights for both patients and healthcare providers seeking reliable cold sore treatment options. With simple application and proven results, zinc sulfate gel could become a go-to remedy for those frequently struggling with herpes labialis recidivans.
The results were promising; the patients using the zinc gel reported less discomfort, and their sores healed more quickly. Importantly, this treatment showed no significant side effects, making it a safe option for managing cold sores. Additionally, the antiseptic properties of zinc sulfate helped prevent any superinfections, adding another layer of benefit to its use.
Overall, our exploration into zinc’s effectiveness provided valuable insights for both patients and healthcare providers seeking reliable cold sore treatment options. With simple application and proven results, zinc sulfate gel could become a go-to remedy for those frequently struggling with herpes labialis recidivans.
Read More
8
We examined how the combination of pomegranate rind extract (PRE) and zinc impacts cold sores, particularly focusing on inflammation. By applying these substances to ex vivo porcine skin, we were able to assess their ability to modulate COX-2, a key player in the inflammation process.
Our findings revealed that the topical application of PRE significantly reduced COX-2 levels in the skin after just six hours and maintained this effect for 24 hours. When we combined PRE with zinc, the results matched those of PRE alone, indicating that zinc didn't add extra benefits to inflammation control when used together.
However, we also noted that zinc alone showed no significant anti-inflammatory effect, highlighting that the benefits we observed were primarily due to the pomegranate extract rather than zinc. This suggests that while zinc is commonly thought beneficial for treating cold sores, its impact on inflammation might be limited unless paired with more potent anti-inflammatory agents like PRE.
In conclusion, pomegranates present a promising approach to managing inflammation and pain associated with cold sores, but zinc’s standalone effectiveness requires reconsideration.
Our findings revealed that the topical application of PRE significantly reduced COX-2 levels in the skin after just six hours and maintained this effect for 24 hours. When we combined PRE with zinc, the results matched those of PRE alone, indicating that zinc didn't add extra benefits to inflammation control when used together.
However, we also noted that zinc alone showed no significant anti-inflammatory effect, highlighting that the benefits we observed were primarily due to the pomegranate extract rather than zinc. This suggests that while zinc is commonly thought beneficial for treating cold sores, its impact on inflammation might be limited unless paired with more potent anti-inflammatory agents like PRE.
In conclusion, pomegranates present a promising approach to managing inflammation and pain associated with cold sores, but zinc’s standalone effectiveness requires reconsideration.
Read More
User Reviews
USERS' SCORE
Moderately Good
Based on 17 Reviews
7.6
- All Reviews
- Positive Reviews
- Negative Reviews
7.5
Improved cold sores
50 people found this helpful
I was initially sceptical about aids for colds, but after experiencing a broken nose and the threat of sinusitis, I began using zinc and vitamin C. I typically suffered from colds for several days, but this time I had just one day of sniffling and a quicker recovery. It seems to have helped with my nose too. However, be cautious as it can cause nausea if taken on an empty stomach.
Read More
9
Strengthened immunity
38 people found this helpful
Each capsule contains 15 mg of zinc and 1 mg of copper, which is perfect for preventing deficiencies and boosting immunity. I've relied on zinc repeatedly at the first signs of a cold, and it's always delivered results. Excellent quality from this manufacturer!
Read More
9
Restored taste
9 people found this helpful
My doctor friend recommended this zinc during our COVID-19 illness, especially after we both lost our sense of taste. I noticed improvement after taking it weekly, while my husband delayed and took longer to recover. It's now my preferred zinc during colds, complements well with monolaurin.
Read More
9
Cured taste abnormality
2 people found this helpful
I was pleased to find that after trying this product, my abnormal taste sensation was entirely rectified, and I've had fewer colds since.
Read More
9
Cold prevention
1 people found this helpful
Works brilliantly! It’s one of the most digestible forms and the best value for money. My family and I use it for preventing colds and viral illnesses, and we fall sick less often. If someone does catch a cold, we double the dose at the onset, resulting in quicker recovery with milder symptoms. I've noticed stronger, shinier nails, and the white spots disappeared. The capsules are small and easy to swallow. I recommend it due to its excellent price and reliability.
Read More
Frequently Asked Questions
7.5
Reduced symptoms
13 people found this helpful
Zinc boosts immunity and has antiviral properties. Whenever I show cold symptoms, I take zinc alongside onion and vitamin C, which usually clears things up within a day or two. It's essential during this pandemic, although the taste is odd, and it can cause nausea if taken on an empty stomach. I've repurchased this and recommend it for overall health.
7.5
Eased cold issues
8 people found this helpful
After a few weeks of using Zinc Balance, my frequent colds significantly decreased. It has effectively addressed my health issues, making me feel more energetic and healthier. I'm impressed with the quality and plan to purchase it again to maintain my immunity.
7.5
Enhanced immunity
2 people found this helpful
This formula is ideal for everyday use. I believe every man should use it for their immune system and prostate health. After starting it, I noticed more energy and fewer cold sores during stressful periods.
7.5
Improved cold sores
50 people found this helpful
I was initially sceptical about aids for colds, but after experiencing a broken nose and the threat of sinusitis, I began using zinc and vitamin C. I typically suffered from colds for several days, but this time I had just one day of sniffling and a quicker recovery. It seems to have helped with my nose too. However, be cautious as it can cause nausea if taken on an empty stomach.
9
Cold prevention
1 people found this helpful
Works brilliantly! It’s one of the most digestible forms and the best value for money. My family and I use it for preventing colds and viral illnesses, and we fall sick less often. If someone does catch a cold, we double the dose at the onset, resulting in quicker recovery with milder symptoms. I've noticed stronger, shinier nails, and the white spots disappeared. The capsules are small and easy to swallow. I recommend it due to its excellent price and reliability.
8
Immunity support
1 people found this helpful
I take this zinc supplement at the first sign of a cold, and it's beneficial for my immune health and skin, as recommended by my beautician.
0
Ineffective for immunity
13 people found this helpful
Zinc sulfate proved to be the cheapest option, but it did not prevent me from catching a cold or experiencing cold sores. I thought my immunity would improve, but the results were disappointing. I experienced significant hair loss and would suggest opting for chelated zinc or other trustworthy brands instead.
9
Restored taste
9 people found this helpful
My doctor friend recommended this zinc during our COVID-19 illness, especially after we both lost our sense of taste. I noticed improvement after taking it weekly, while my husband delayed and took longer to recover. It's now my preferred zinc during colds, complements well with monolaurin.
7
We explored the relationship between zinc levels and recurrent herpes labialis (cold sores) through a study involving 43 patients with a history of this condition and 42 healthy individuals. By measuring serum zinc levels using a colorimetric method, we aimed to find out whether these levels differ significantly between both groups and how they relate to the severity and duration of cold sore episodes.
Although we found that serum zinc levels did not significantly differ between the patients and healthy subjects, we observed an interesting correlation regarding recovery times. Specifically, lower serum zinc levels appeared to be linked to longer recovery periods from cold sores. This suggests that zinc might play a role in speeding up recovery, though it was not a significant factor influencing relapse frequency or patient demographics such as age and sex.
Overall, while the study didn’t establish a direct benefit of zinc supplementation, the findings indicate that zinc deficiency might contribute to longer-lasting cold sores. Therefore, we suggest that evaluating zinc levels in patients experiencing recurrent cold sores could be beneficial and that zinc supplementation may be worth considering in treatment protocols.
Although we found that serum zinc levels did not significantly differ between the patients and healthy subjects, we observed an interesting correlation regarding recovery times. Specifically, lower serum zinc levels appeared to be linked to longer recovery periods from cold sores. This suggests that zinc might play a role in speeding up recovery, though it was not a significant factor influencing relapse frequency or patient demographics such as age and sex.
Overall, while the study didn’t establish a direct benefit of zinc supplementation, the findings indicate that zinc deficiency might contribute to longer-lasting cold sores. Therefore, we suggest that evaluating zinc levels in patients experiencing recurrent cold sores could be beneficial and that zinc supplementation may be worth considering in treatment protocols.
8
We aimed to understand how zinc might affect the occurrence and duration of cold sores, also known as herpes labialis. In our study, we treated 20 patients, mostly women with an average age of 26.6, who experienced more than six episodes of cold sores each year. They received zinc sulphate at a dose of 22.5 mg twice daily during specific months over a year while we monitored their symptoms for 12 months.
Our results were promising. Patients reported a decrease in the frequency of cold sore episodes, averaging fewer than four instances per year. Moreover, the duration of these episodes was also shortened to around 5.7 days, significantly less than usual for these conditions.
Thus, we can say that systemic zinc sulphate seemed to effectively reduce both the number of cold sore outbreaks and the recovery time. This suggests that zinc might be a beneficial option for individuals who struggle with recurrent cold sores.
Our results were promising. Patients reported a decrease in the frequency of cold sore episodes, averaging fewer than four instances per year. Moreover, the duration of these episodes was also shortened to around 5.7 days, significantly less than usual for these conditions.
Thus, we can say that systemic zinc sulphate seemed to effectively reduce both the number of cold sore outbreaks and the recovery time. This suggests that zinc might be a beneficial option for individuals who struggle with recurrent cold sores.
9
We conducted a double-blind, placebo-controlled clinical trial to explore the effectiveness of a zinc oxide/glycine cream in treating cold sores caused by facial and circumoral herpes. By dividing 46 participants into two groups, one receiving the zinc treatment and the other a placebo, we aimed to measure how this formulation affected the duration and severity of cold sore symptoms.
Our results were quite promising! Participants who began using the zinc oxide/glycine cream within the first 24 hours of noticing symptoms experienced cold sore lesions that lasted only an average of 5 days, compared to 6.5 days for those on the placebo. Additionally, we noticed a significant reduction in the overall severity of their symptoms, including blistering, soreness, itching, and tingling.
As for side effects, subjects treated with the zinc cream experienced only minor and reversible issues typical of ionic zinc salt solutions. This indicates that the zinc oxide/glycine cream is not only effective but also safe for treating cold sores, presenting a valuable option for many people seeking relief from this common condition.
Our results were quite promising! Participants who began using the zinc oxide/glycine cream within the first 24 hours of noticing symptoms experienced cold sore lesions that lasted only an average of 5 days, compared to 6.5 days for those on the placebo. Additionally, we noticed a significant reduction in the overall severity of their symptoms, including blistering, soreness, itching, and tingling.
As for side effects, subjects treated with the zinc cream experienced only minor and reversible issues typical of ionic zinc salt solutions. This indicates that the zinc oxide/glycine cream is not only effective but also safe for treating cold sores, presenting a valuable option for many people seeking relief from this common condition.
8
We examined how the combination of pomegranate rind extract (PRE) and zinc impacts cold sores, particularly focusing on inflammation. By applying these substances to ex vivo porcine skin, we were able to assess their ability to modulate COX-2, a key player in the inflammation process.
Our findings revealed that the topical application of PRE significantly reduced COX-2 levels in the skin after just six hours and maintained this effect for 24 hours. When we combined PRE with zinc, the results matched those of PRE alone, indicating that zinc didn't add extra benefits to inflammation control when used together.
However, we also noted that zinc alone showed no significant anti-inflammatory effect, highlighting that the benefits we observed were primarily due to the pomegranate extract rather than zinc. This suggests that while zinc is commonly thought beneficial for treating cold sores, its impact on inflammation might be limited unless paired with more potent anti-inflammatory agents like PRE.
In conclusion, pomegranates present a promising approach to managing inflammation and pain associated with cold sores, but zinc’s standalone effectiveness requires reconsideration.
Our findings revealed that the topical application of PRE significantly reduced COX-2 levels in the skin after just six hours and maintained this effect for 24 hours. When we combined PRE with zinc, the results matched those of PRE alone, indicating that zinc didn't add extra benefits to inflammation control when used together.
However, we also noted that zinc alone showed no significant anti-inflammatory effect, highlighting that the benefits we observed were primarily due to the pomegranate extract rather than zinc. This suggests that while zinc is commonly thought beneficial for treating cold sores, its impact on inflammation might be limited unless paired with more potent anti-inflammatory agents like PRE.
In conclusion, pomegranates present a promising approach to managing inflammation and pain associated with cold sores, but zinc’s standalone effectiveness requires reconsideration.
References
- Ranjbar Z, Zahed M, Ranjbar MA, Shirmardan Z. Comparative study of serum zinc concentration in recurrent herpes labialis patients and healthy individuals. BMC Oral Health. 2020;20:296. doi:10.1186/s12903-020-01277-2
- Houston DM, Bugert J, Denyer SP, Heard CM. Anti-inflammatory activity of Punica granatum L. (Pomegranate) rind extracts applied topically to ex vivo skin. Eur J Pharm Biopharm. 2017;112:30. doi:10.1016/j.ejpb.2016.11.014
- Khozeimeh F, Jafari N, Attar AM, Jafari S, Ataie M. Comparative analysis of salivary zinc level in recurrent herpes labialis. Dent Res J (Isfahan). 2012;9:19. doi:10.4103/1735-3327.92922
- Opstelten W, Neven AK, Eekhof J. Treatment and prevention of herpes labialis. Can Fam Physician. 2008;54:1683.
- Femiano F, Gombos F, Scully C. Recurrent herpes labialis: a pilot study of the efficacy of zinc therapy. J Oral Pathol Med. 2005;34:423.
- Singh BB, Udani J, Vinjamury SP, Der-Martirosian C, Gandhi S, et al. Safety and effectiveness of an L-lysine, zinc, and herbal-based product on the treatment of facial and circumoral herpes. Altern Med Rev. 2005;10:123.
- Godfrey HR, Godfrey NJ, Godfrey JC, Riley D. A randomized clinical trial on the treatment of oral herpes with topical zinc oxide/glycine. Altern Ther Health Med. 2001;7:49.
- Kneist W, Hempel B, Borelli S. [Clinical double-blind trial of topical zinc sulfate for herpes labialis recidivans]. Arzneimittelforschung. 1995;45:624.
- Brody I. Topical treatment of recurrent herpes simplex and post-herpetic erythema multiforme with low concentrations of zinc sulphate solution. Br J Dermatol. 1981;104:191.
