We investigated the impact of dispersible zinc tablets on postoperative sore throat (POST) experienced by patients after endotracheal intubation. In our study, 88 patients were divided into two groups. One group received a 40 mg zinc tablet, while the other received a placebo 30 minutes before their surgery.
Our findings revealed that the zinc group reported significantly fewer instances of POST at the 4-hour mark compared to the placebo group. Specifically, only 6.8% of patients in the zinc group experienced POST, while a higher 31.8% in the placebo group did. Furthermore, none of the patients taking zinc reported severe sore throat, a stark contrast to three patients in the placebo group who did.
Additionally, we noted lower severity ratings for sore throat in the zinc group at various time intervals post-surgery. The results emphasize that taking zinc tablets before surgery can effectively mitigate the incidence and discomfort of sore throat following intubation, presenting a simple solution for a common postoperative issue.
Read More
9
Zinc reduces postoperative sore throat
The Effect of Zinc Lozenge on Postoperative Sore Throat: A Prospective Randomized, Double-Blinded, Placebo-Controlled Study.
We explored the potential benefits of zinc lozenges for easing postoperative sore throat (POST), a common discomfort following endotracheal intubation. By conducting a randomized, double-blinded trial with 79 patients undergoing low- to moderate-risk surgeries, we divided participants into two groups: one received zinc lozenges, while the other was given a placebo.
Our findings revealed promising results. At the crucial four-hour mark post-surgery, only 7% of patients who took zinc experienced POST, compared to 29% in the placebo group. Interestingly, the difference was even more pronounced right after surgery, where the zinc group reported a 0% incidence of POST versus 24% for the control group.
Moreover, the severity of sore throat symptoms was notably less intense among those in the zinc group. Those with mild and moderate sore throat pains reported significantly lower severity scores. These results suggest that a single dose of 40 mg of zinc lozenges taken just 30 minutes before surgery can greatly aid in reducing both the occurrence and discomfort of POST in the early hours after surgery.
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9.5
Zinc reduces postoperative sore throat
A randomised, double-blind, comparative study of preoperative magnesium sulphate versus zinc sulphate gargle for prevention of postoperative sore throat following endotracheal intubation.
We conducted a study to understand how well zinc can help prevent postoperative sore throat (POST) after endotracheal intubation. We compared the effects of gargling with zinc sulphate versus magnesium sulphate in a controlled trial involving 132 patients. Those in the zinc group received a solution with 40 mg of elemental zinc, while the magnesium group used 20 mg/kg of magnesium sulphate, with a control group receiving only dextrose.
Our findings showed that the group using zinc sulphate experienced notably lower rates of sore throat compared to those using magnesium sulphate. Specifically, the incidence of mild POST was significantly lower in the zinc group, especially during the first four hours after surgery. Overall, zinc gargle proved to be more effective in reducing sore throat compared to magnesium sulphate, demonstrating its potential benefits in postoperative care.
These results highlight the importance of zinc as a simple yet effective intervention to reduce discomfort for patients following surgery. By using zinc gargle preoperatively, we can potentially improve patient outcomes related to postoperative sore throat.
Read More
Most Useful Reviews
9
Rapid sore throat relief
94 people found this helpful
Works like a miracle! I've been getting sick about 4 times a year, often needing antibiotics, but this product is amazing for avoiding colds. I've tried various remedies, but nothing compares to this. My colds generally start with a sore throat and discomfort, and this product can improve my condition within just 4-6 hours. If I use it early, it really does work, and I won't reach for pills again until needed.
Read More
10
Fast sore throat relief
This product is good—zinc in an easily absorbable form, with copper. I've been taking it myself and also give it to my child. After 1.5 months, I've noticed that when I take it at the first sign of ARVI, my sore throat almost disappears overnight, with overall symptom relief.
Read More
10
Maintains immunity well
This is the best zinc I've ever taken! I have it with vitamin C and caprylic acid in the morning. Even minor malaise or a sore throat vanishes. I've been taking it for 2 months for immunity support.
A randomised, double-blind, comparative study of preoperative magnesium sulphate versus zinc sulphate gargle for prevention of postoperative sore throat following endotracheal intubation.
We conducted a study to understand how well zinc can help prevent postoperative sore throat (POST) after endotracheal intubation. We compared the effects of gargling with zinc sulphate versus magnesium sulphate in a controlled trial involving 132 patients. Those in the zinc group received a solution with 40 mg of elemental zinc, while the magnesium group used 20 mg/kg of magnesium sulphate, with a control group receiving only dextrose.
Our findings showed that the group using zinc sulphate experienced notably lower rates of sore throat compared to those using magnesium sulphate. Specifically, the incidence of mild POST was significantly lower in the zinc group, especially during the first four hours after surgery. Overall, zinc gargle proved to be more effective in reducing sore throat compared to magnesium sulphate, demonstrating its potential benefits in postoperative care.
These results highlight the importance of zinc as a simple yet effective intervention to reduce discomfort for patients following surgery. By using zinc gargle preoperatively, we can potentially improve patient outcomes related to postoperative sore throat.
Read More
9.5
Zinc reduces postoperative sore throat
Preoperative oral zinc tablet decreases incidence of postoperative sore throat.
We investigated the impact of dispersible zinc tablets on postoperative sore throat (POST) experienced by patients after endotracheal intubation. In our study, 88 patients were divided into two groups. One group received a 40 mg zinc tablet, while the other received a placebo 30 minutes before their surgery.
Our findings revealed that the zinc group reported significantly fewer instances of POST at the 4-hour mark compared to the placebo group. Specifically, only 6.8% of patients in the zinc group experienced POST, while a higher 31.8% in the placebo group did. Furthermore, none of the patients taking zinc reported severe sore throat, a stark contrast to three patients in the placebo group who did.
Additionally, we noted lower severity ratings for sore throat in the zinc group at various time intervals post-surgery. The results emphasize that taking zinc tablets before surgery can effectively mitigate the incidence and discomfort of sore throat following intubation, presenting a simple solution for a common postoperative issue.
Read More
9
Zinc reduces postoperative sore throat
The Effect of Zinc Lozenge on Postoperative Sore Throat: A Prospective Randomized, Double-Blinded, Placebo-Controlled Study.
We explored the potential benefits of zinc lozenges for easing postoperative sore throat (POST), a common discomfort following endotracheal intubation. By conducting a randomized, double-blinded trial with 79 patients undergoing low- to moderate-risk surgeries, we divided participants into two groups: one received zinc lozenges, while the other was given a placebo.
Our findings revealed promising results. At the crucial four-hour mark post-surgery, only 7% of patients who took zinc experienced POST, compared to 29% in the placebo group. Interestingly, the difference was even more pronounced right after surgery, where the zinc group reported a 0% incidence of POST versus 24% for the control group.
Moreover, the severity of sore throat symptoms was notably less intense among those in the zinc group. Those with mild and moderate sore throat pains reported significantly lower severity scores. These results suggest that a single dose of 40 mg of zinc lozenges taken just 30 minutes before surgery can greatly aid in reducing both the occurrence and discomfort of POST in the early hours after surgery.
Read More
8
Zinc's role in sore throat treatment
The Effectiveness of a Dietary Supplement with Honey, Propolis, Extract, and Zinc in Children Affected by Acute Tonsillopharyngitis: An Open, Randomized, and Controlled Trial.
We evaluated a promising dietary supplement that combines honey, propolis, and zinc to see how effective it could be for children suffering from acute tonsillopharyngitis, a type of sore throat. In this open-label, randomized, and controlled study, we compared the supplement along with standard care against standard care alone over six days.
The results revealed that incorporating the supplement with standard care led to notable improvements in certain symptoms associated with sore throat, such as throat pain and swallowing difficulties by day four and six. Although zinc was part of the blend, it was challenging to pinpoint its independent effect, given that it was studied alongside honey and propolis.
Interestingly, only one child in the standard care group needed additional medications like ibuprofen, highlighting that the supplement may reduce the need for further treatment. Importantly, we did not report any adverse events, making this combination a potential safe addition to treatment.
Overall, while the study presents encouraging results regarding the adjunctive use of the supplement in treating sore throat, it remains unclear how much zinc alone contributes to its effectiveness.
Read More
8
Zinc's variable effectiveness for sore throat
Zinc deficits, mucositis, and mucosal macrophage perturbation: is there a relationship?
We examined recent findings regarding zinc's impact on sore throat, particularly in post-operative settings. Some studies have reported that specific zinc formulations, like polaprezinc, can effectively reduce symptoms associated with sore throat after procedures like endotracheal intubation.
Importantly, zinc sulfate showed mixed results, with one review suggesting it did not significantly decrease the occurrence or intensity of oral mucositis in cancer patients. However, there are indications that certain zinc preparations may still hold promise in specific contexts, such as managing sore throat post-surgery.
Overall, while zinc's benefits in sore throat treatment appear to vary, ongoing research explores the best applications and formulations of zinc to potentially ease discomfort. As such, individuals seeking relief should keep an eye on emerging studies that could clarify zinc's role in throat health.
Works like a miracle! I've been getting sick about 4 times a year, often needing antibiotics, but this product is amazing for avoiding colds. I've tried various remedies, but nothing compares to this. My colds generally start with a sore throat and discomfort, and this product can improve my condition within just 4-6 hours. If I use it early, it really does work, and I won't reach for pills again until needed.
Read More
10
Fast sore throat relief
This product is good—zinc in an easily absorbable form, with copper. I've been taking it myself and also give it to my child. After 1.5 months, I've noticed that when I take it at the first sign of ARVI, my sore throat almost disappears overnight, with overall symptom relief.
Read More
10
Maintains immunity well
This is the best zinc I've ever taken! I have it with vitamin C and caprylic acid in the morning. Even minor malaise or a sore throat vanishes. I've been taking it for 2 months for immunity support.
Read More
9
Effective for colds
Good zinc for colds and sore throat; I absorb the capsule's contents, and it helps very well.
Read More
9
Good for recovery
Zinc is especially beneficial for men’s health and supports immune function, reducing the risk of inflammations. It's effective in preventing viral infections and alleviating symptoms like sore throat and runny nose, helping to recover from colds more rapidly. The quality of this zinc is superb!
A sore throat, also known as pharyngitis, is a common condition characterized by pain, scratchiness, or irritation of the throat. It can occur as a result of various factors, including viral infections like the common cold or flu, bacterial infections such as strep throat, allergies, dry air, or even irritants like smoke and pollution. Symptoms often manifest as a sensation of discomfort during swallowing and may be accompanied by swelling, redness, or the presence of white patches on the tonsils or throat lining.
Most sore throats are mild and resolve on their own within a week or so, often treated with home remedies such as warm salt water gargles, lozenges, and hydration. However, if the sore throat is severe, persistent, or associated with other concerning symptoms such as high fever, difficulty swallowing, or difficulty breathing, it's essential to consult a healthcare professional, as this may indicate a more serious condition that requires medical intervention. Proper diagnosis and treatment are crucial, especially if a bacterial infection is suspected, as it may necessitate antibiotics for effective treatment.
Zinc is a versatile metal known for its various applications in industry and health. It is a bluish-white metallic element represented by the symbol Zn and atomic number 30 on the periodic table. Zinc is primarily used for galvanizing steel to prevent rusting, in the manufacturing of alloys, and as a component in batteries. Additionally, zinc plays a crucial role in biological processes, making it an essential trace element in the human diet. It is involved in immune function, protein synthesis, wound healing, and DNA synthesis, highlighting its importance in maintaining overall health and well-being.
Zinc has been studied for its potential effects on the immune system, and some evidence suggests it may help alleviate sore throat symptoms. Particularly, zinc lozenges or syrups may shorten the duration of a sore throat when taken at the onset of symptoms. The reasoning behind this is that zinc can inhibit the replication of the virus responsible for the cold and boost immune response, thus potentially providing some relief.
However, it’s important to use zinc cautiously, as high doses can lead to side effects such as nausea or a bad taste in the mouth. Most health experts recommend opting for zinc in moderate doses, ideally through lozenges, which can also provide some soothing effects. While zinc might not be a cure-all, it can be a helpful part of a broader treatment plan that includes rest, hydration, and over-the-counter pain relievers. If your sore throat persists or is accompanied by other severe symptoms, consulting with a healthcare professional is advisable.
Based on user reviews, the time it takes to see results from taking zinc for a sore throat can vary. Many users report that taking zinc at the first sign of symptoms often leads to quick relief. For example, one user noted that their sore throat "almost disappears overnight" after starting zinc at the onset of symptoms Read Review. Another mentioned that they typically saw symptom resolution within 2-3 days when symptoms persisted Read Review.
Several users emphasize the importance of promptly taking zinc, indicating that immediate action is key—results may be felt quickly when consumed at the first indication of discomfort. Others found that when taken consistently over a couple of weeks, zinc contributed to overall immunity support, which may help in preventing sore throats altogether Read Review, Read Review. Overall, while some experience relief within a day, others note a duration of a few days for symptom alleviation.
Recent scientific research suggests that a combination of honey, propolis, and zinc may be beneficial for managing sore throat symptoms, particularly in children suffering from acute tonsillopharyngitis. A study specifically highlighted the effectiveness of this supplement alongside standard care, showing improvements in throat pain and swallowing difficulties by days four and six [1]. While the study established a positive correlation, it is important to note that the independent effect of zinc was difficult to isolate, as it was studied in conjunction with honey and propolis. Nevertheless, the results indicate that this blend could potentially reduce the need for additional medications like ibuprofen, making it a safe adjunct to traditional treatment.
On the other hand, research focused on zinc alone presents mixed results. For instance, while some studies have demonstrated zinc’s effectiveness in reducing postoperative sore throat, particularly after endotracheal intubation [5], its impact on sore throat related to common colds was not conclusively significant [9]. Consequently, while the incorporation of zinc in various forms shows promise, its role in treating sore throat specifically lacks a definitive consensus. Therefore, while there is some support for certain formulations of zinc as a treatment adjunct, the evidence remains varied, necessitating further investigation to clarify its efficacy and specific applications in sore throat management.
Based on user reviews, many individuals have reported significant improvements in their symptoms after using zinc for sore throats and colds. A notable number of users mention that taking zinc at the first sign of symptoms led to rapid relief, with one user stating their sore throat "almost disappears overnight" after starting zinc Read Review. Others also highlighted that zinc effectively alleviated malaise and throat discomfort; for instance, one user shared that any minor symptoms vanished entirely within a short period of taking zinc Read Review.
In terms of duration for symptom resolution, multiple reviews indicate that while some experienced quick relief, others noted that lingering symptoms could take 2-3 days to completely resolve Read Review. Users also emphasized the importance of taking zinc early and consistently; one reviewer mentioned that this approach dramatically helped mitigate common throat issues throughout cold seasons Read Review. However, it's important to note that individual results can vary, and while many have found success with zinc, others may experience different outcomes depending on their unique situations.
According to user reviews, many individuals have reported positive experiences when combining zinc with other supplements to manage sore throat symptoms. Users commonly mention pairing zinc with vitamin C, which seems to enhance its effectiveness. One user specifically noted that taking zinc alongside vitamin C and caprylic acid resulted in the quick resolution of even minor symptoms, such as sore throats Read Review. Additionally, another reviewer highlighted the synergy between zinc and vitamins A, C, D, and selenium, suggesting that this combination helps efficiently tackle sore throat alongside other cold symptoms Read Review.
Furthermore, some users have found that taking zinc with quercetin also provides substantial relief, helping with both sore throats and sniffles Read Review. Overall, it seems that when combined with other vitamins and supplements, zinc not only aids in alleviating sore throat discomfort but may also support faster recovery from cold-related symptoms. Users have remarked that this combination approach can lead to a more robust immune response and quicker symptom resolution Read Review.
Based on user reviews, the consensus on the right dose of zinc for treating sore throat varies, with many individuals reporting positive results when they start taking zinc at the first sign of symptoms. For instance, one user mentions taking 2 capsules as soon as they feel unwell, leading to a swift resolution of symptoms within a couple of days Read Review. Another user highlights that they take zinc every two hours at the onset of a sore throat for significant relief, indicating a more frequent dosing strategy Read Review.
Additionally, users often combine zinc with other supplements; one user noted taking it alongside Vitamin C, which seems to enhance its effectiveness in alleviating cold symptoms, including sore throat Read Review. Another individual emphasizes consistent daily use of zinc while increasing the dosage during illness to help cope with sore throat and nasal symptoms Read Review. Overall, there isn't a one-size-fits-all answer, but starting zinc intake at the onset of sore throat symptoms and adjusting frequency or dosage according to personal response seems to be a common approach among users.
10
Fast sore throat relief
This product is good—zinc in an easily absorbable form, with copper. I've been taking it myself and also give it to my child. After 1.5 months, I've noticed that when I take it at the first sign of ARVI, my sore throat almost disappears overnight, with overall symptom relief.
9
Immediate symptom relief
As soon as I feel unwell or have a sore throat, I take 2 capsules. There aren't any symptoms left, but if it lingers, it can take 2-3 days.
10
Maintains immunity well
This is the best zinc I've ever taken! I have it with vitamin C and caprylic acid in the morning. Even minor malaise or a sore throat vanishes. I've been taking it for 2 months for immunity support.
9
Prevents symptoms effectively
This good zinc helps support my body during autumn's illness season. At the first signs of illness or sore throat, I take it, and all symptoms disappear quickly.
9
Great for symptoms
Zinc, coupled with vitamins A, C, D, and selenium, effectively addresses sore throat, runny nose, and fever, with symptoms resolving in 3-5 days. This is an excellent combination, especially for children.
9
Combines with quercetin
Taking zinc with quercetin works well to relieve sore throats and sniffles. It's been effective for me.
7.5
Essential for cold symptoms
Always needed! I keep it in the cabinet. At the first sign of a sore throat, I start taking it along with Vitamin C in the evening, and everything clears up.
9
Pleasant lozenges
I switched to these lozenges after using a different zinc form and am pleased with their pleasant taste. They ease my sore throat effectively without causing nausea, which I experienced with past products. I take them every two hours at the onset of soreness for significant relief—highly recommended!
7.5
Helps with congestion
Excellent! I take zinc lozenges for myself and the kids because of our regular runny noses and sore throats. Zinc seems to really help the body cope with these issues.
8
Zinc's role in sore throat treatment
The Effectiveness of a Dietary Supplement with Honey, Propolis, Extract, and Zinc in Children Affected by Acute Tonsillopharyngitis: An Open, Randomized, and Controlled Trial.
We evaluated a promising dietary supplement that combines honey, propolis, and zinc to see how effective it could be for children suffering from acute tonsillopharyngitis, a type of sore throat. In this open-label, randomized, and controlled study, we compared the supplement along with standard care against standard care alone over six days.
The results revealed that incorporating the supplement with standard care led to notable improvements in certain symptoms associated with sore throat, such as throat pain and swallowing difficulties by day four and six. Although zinc was part of the blend, it was challenging to pinpoint its independent effect, given that it was studied alongside honey and propolis.
Interestingly, only one child in the standard care group needed additional medications like ibuprofen, highlighting that the supplement may reduce the need for further treatment. Importantly, we did not report any adverse events, making this combination a potential safe addition to treatment.
Overall, while the study presents encouraging results regarding the adjunctive use of the supplement in treating sore throat, it remains unclear how much zinc alone contributes to its effectiveness.
9.5
Zinc reduces postoperative sore throat
Preoperative oral zinc tablet decreases incidence of postoperative sore throat.
We investigated the impact of dispersible zinc tablets on postoperative sore throat (POST) experienced by patients after endotracheal intubation. In our study, 88 patients were divided into two groups. One group received a 40 mg zinc tablet, while the other received a placebo 30 minutes before their surgery.
Our findings revealed that the zinc group reported significantly fewer instances of POST at the 4-hour mark compared to the placebo group. Specifically, only 6.8% of patients in the zinc group experienced POST, while a higher 31.8% in the placebo group did. Furthermore, none of the patients taking zinc reported severe sore throat, a stark contrast to three patients in the placebo group who did.
Additionally, we noted lower severity ratings for sore throat in the zinc group at various time intervals post-surgery. The results emphasize that taking zinc tablets before surgery can effectively mitigate the incidence and discomfort of sore throat following intubation, presenting a simple solution for a common postoperative issue.
7
Zinc's effects on sore throat
Duration of symptoms and plasma cytokine levels in patients with the common cold treated with zinc acetate. A randomized, double-blind, placebo-controlled trial.
We conducted a rigorous study to see how zinc acetate lozenges might help reduce the painful and annoying symptoms of the common cold, particularly sore throats. In a well-structured environment, we recruited 50 volunteers who started experiencing cold symptoms within the last 24 hours. Participants were randomly assigned to receive either zinc lozenges or a placebo, taking one every few hours during the day.
Over the course of the study, we monitored various symptoms, including sore throat, and measured participants' plasma zinc and cytokine levels on the first day and as they recovered. We observed that those who took zinc lozenges experienced a shorter duration of cold symptoms, with cough showing notable improvement.
However, when it came to sore throats specifically, while there were positive results, the changes didn't stand out as significantly different from those who received the placebo. So, while zinc may play a role in easing cold symptoms overall, its particular impact on sore throat isn’t conclusively proven in our findings.
References
Cardinale F, Barattini DF, Martinucci V, Bordea MM, Barattini L, et al. The Effectiveness of a Dietary Supplement with Honey, Propolis, Extract, and Zinc in Children Affected by Acute Tonsillopharyngitis: An Open, Randomized, and Controlled Trial. Pharmaceuticals (Basel). 2024;17. doi:10.3390/ph17060804
Cardinale F, Barattini DF, Sbrocca F, Centi A, Giuntini G, et al. The Effects of a Dietary Supplement (PediaFlù) Plus Standard of Care in Children With Acute Tonsillopharyngitis/Rhinopharyngitis: Protocol for a Randomized Controlled Trial. JMIR Res Protoc. 2024;13:e53703. doi:10.2196/53703
Bhanwra A, Palta S, Saroa R, Saxena P, Bhanwra S, et al. Role of preoperative zinc, magnesium and budesonide gargles in Postoperative Sore Throat (POST) - a randomised control trial. BMC Anesthesiol. 2024;24:164. doi:10.1186/s12871-024-02534-5
Mondal AK, Maiti AK, Chattopadhyay S, Bhar D. A randomised, double-blind, comparative study of preoperative magnesium sulphate versus zinc sulphate gargle for prevention of postoperative sore throat following endotracheal intubation. Indian J Anaesth. 2023;67:S261. doi:10.4103/ija.ija_975_22
Sarkar T, Mandal T. Preoperative oral zinc tablet decreases incidence of postoperative sore throat. Indian J Anaesth. 2020;64:409. doi:10.4103/ija.IJA_959_19
Thomsen M, Vitetta L. Zinc deficits, mucositis, and mucosal macrophage perturbation: is there a relationship?. Curr Opin Clin Nutr Metab Care. 2019;22:365. doi:10.1097/MCO.0000000000000588
Farhang B, Grondin L. The Effect of Zinc Lozenge on Postoperative Sore Throat: A Prospective Randomized, Double-Blinded, Placebo-Controlled Study. Anesth Analg. 2018;126:78. doi:10.1213/ANE.0000000000002494
Sun GB, Sun N, Tang HH, Zhu QB, Wen W, et al. Zinc sulfate therapy of vocal process granuloma. Eur Arch Otorhinolaryngol. 2012;269:2087. doi:10.1007/s00405-012-1971-1
Prasad AS, Fitzgerald JT, Bao B, Beck FW, Chandrasekar PH. Duration of symptoms and plasma cytokine levels in patients with the common cold treated with zinc acetate. A randomized, double-blind, placebo-controlled trial. Ann Intern Med. 2000;133:245.