Overview
SCIENTIFIC SCORE
Possibly Effective
Based on 7 Researches
7.7
USERS' SCORE
Good
Based on 4 Reviews
8.5
Supplement Facts
Serving Size: 1 Softgel
Amount Per Serving
%DV
Vitamin D (as D3 Cholecalciferol)
125 mcg (5,000 IU)
625%
Top Medical Research Studies
8
We explored the potential connection between vitamin D levels and headaches through a thorough investigation using two-sample Mendelian randomization analysis. Our goal was to determine if there’s a causal relationship between high vitamin D levels and the risk of experiencing headaches.
Our findings revealed that higher levels of vitamin D are linked to a lower risk of headaches. Specifically, we found that vitamin D may have a preventive effect, reducing the likelihood of headaches occurring. However, we also observed that there is no evidence to suggest that headaches cause changes in vitamin D levels.
This means while supplementing vitamin D may help keep headaches at bay, headaches themselves do not appear to affect vitamin D levels. This information contributes valuable insights into how maintaining sufficient vitamin D could play a role in headache management.
Our findings revealed that higher levels of vitamin D are linked to a lower risk of headaches. Specifically, we found that vitamin D may have a preventive effect, reducing the likelihood of headaches occurring. However, we also observed that there is no evidence to suggest that headaches cause changes in vitamin D levels.
This means while supplementing vitamin D may help keep headaches at bay, headaches themselves do not appear to affect vitamin D levels. This information contributes valuable insights into how maintaining sufficient vitamin D could play a role in headache management.
8
We aimed to investigate how vitamin D levels might impact migraine occurrences in children. Recent research highlighted that many youngsters experience migraines, and intriguingly, vitamin D has been linked to various neurological conditions.
In diving into existing literature, we found a noteworthy connection between low vitamin D levels and the frequency and duration of migraine attacks in pediatric patients. Our review suggested that vitamin D supplementation could potentially enhance the quality of life for those suffering from migrainous headaches.
While vitamin D is often talked about in terms of its benefits for bone health, its implications for migraine management in children seem promising. We recognized the potential for vitamin D to play a meaningful role in alleviating headaches, especially in a time when many children face this debilitating condition.
In diving into existing literature, we found a noteworthy connection between low vitamin D levels and the frequency and duration of migraine attacks in pediatric patients. Our review suggested that vitamin D supplementation could potentially enhance the quality of life for those suffering from migrainous headaches.
While vitamin D is often talked about in terms of its benefits for bone health, its implications for migraine management in children seem promising. We recognized the potential for vitamin D to play a meaningful role in alleviating headaches, especially in a time when many children face this debilitating condition.
7
We investigated how vitamin D levels relate to migraines and whether vitamin D supplementation can help people who suffer from these headaches. Our analysis included a range of studies, focusing on differences in vitamin D levels between migraine sufferers and those who do not experience migraines.
We found that migraineurs had significantly lower levels of serum 25-hydroxy vitamin D compared to nonmigraineurs, indicating a noteworthy connection. In fact, vitamin D deficiency was shown to be associated with an increased likelihood of experiencing migraines.
When it comes to treatment, we observed that taking vitamin D supplements seemed to help reduce the frequency of migraines. However, it's important to note that while vitamin D supplementation made a difference in how often migraines occurred, it did not significantly impact how long these headaches lasted or their severity.
Overall, it appears that while vitamin D might help lessen the occurrence of migraines for some, it may not be a solution for everyone, particularly in regards to reducing the intensity or duration of such headaches.
We found that migraineurs had significantly lower levels of serum 25-hydroxy vitamin D compared to nonmigraineurs, indicating a noteworthy connection. In fact, vitamin D deficiency was shown to be associated with an increased likelihood of experiencing migraines.
When it comes to treatment, we observed that taking vitamin D supplements seemed to help reduce the frequency of migraines. However, it's important to note that while vitamin D supplementation made a difference in how often migraines occurred, it did not significantly impact how long these headaches lasted or their severity.
Overall, it appears that while vitamin D might help lessen the occurrence of migraines for some, it may not be a solution for everyone, particularly in regards to reducing the intensity or duration of such headaches.
Most Useful Reviews
9
No more headaches
Good composition, fast delivery, and high-quality packaging. The capsules are a tad large but easy to swallow and taste citrusy. I've taken one daily for ten days, along with other supplements. I’ve noticed significant benefits; headaches have ceased, fatigue has reduced, and my mood has improved greatly. I highly recommend it for those interested in sports, fitness, or dieting, as omega-3 energises and replenishes the body effectively.
9
Headaches gone
All is well; I feel good. This supplement lasts a long time for the price, and I've noticed my headaches have disappeared, leaving me feeling lighter.
9
No side effects
Some vitamin D brands cause headaches, but this one has no side effects for me.
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 7 Researches
7.7
- All Researches
9
We conducted a clinical trial to investigate the effects of vitamin D supplementation alongside topiramate, a medication commonly used for migraine prevention in children aged 5 to 14. In this double-blind study, participants were divided into two groups: one received vitamin D with their topiramate treatment, while the other received a placebo.
After four months, we observed that those who took vitamin D experienced a significant reduction in the monthly frequency of headache attacks compared to the placebo group. We noted that children taking vitamin D also reported less disability from their migraines and a higher percentage showed a good response to the treatment.
Furthermore, the side effects were relatively similar between both groups, suggesting that combining vitamin D with topiramate is a safe and well-tolerated option. Overall, our findings indicate that vitamin D supplementation could enhance migraine management in pediatric patients.
After four months, we observed that those who took vitamin D experienced a significant reduction in the monthly frequency of headache attacks compared to the placebo group. We noted that children taking vitamin D also reported less disability from their migraines and a higher percentage showed a good response to the treatment.
Furthermore, the side effects were relatively similar between both groups, suggesting that combining vitamin D with topiramate is a safe and well-tolerated option. Overall, our findings indicate that vitamin D supplementation could enhance migraine management in pediatric patients.
8
Combined treatment benefits migraines
We conducted a randomized, triple-blinded, placebo-controlled trial focusing on the effects of vitamin D and probiotic co-supplementation on migraine headaches. This study included adult patients aged 18 to 55 diagnosed with migraines, specifically using the International Classification of Headache Disorders-3 criteria.
Over a 12-week period, participants received either 50,000 IU of vitamin D plus a daily probiotic or a placebo. We assessed their migraine symptoms through reliable questionnaires and self-reported diaries, tracking headache frequency, duration, and intensity. We also measured their mental health, daily functioning, and inflammation markers during the trial.
Our findings indicated that the combination of vitamin D and probiotics provided beneficial effects on migraine characteristics, including improved mental health outcomes. Although we did not isolate the impact of vitamin D alone, the results suggest that it may play a role in migraine management when paired with probiotics. Further studies are needed to firmly establish these effects and better understand the potential of vitamin D as a treatment option for headaches.
Over a 12-week period, participants received either 50,000 IU of vitamin D plus a daily probiotic or a placebo. We assessed their migraine symptoms through reliable questionnaires and self-reported diaries, tracking headache frequency, duration, and intensity. We also measured their mental health, daily functioning, and inflammation markers during the trial.
Our findings indicated that the combination of vitamin D and probiotics provided beneficial effects on migraine characteristics, including improved mental health outcomes. Although we did not isolate the impact of vitamin D alone, the results suggest that it may play a role in migraine management when paired with probiotics. Further studies are needed to firmly establish these effects and better understand the potential of vitamin D as a treatment option for headaches.
8
We explored the potential connection between vitamin D levels and headaches through a thorough investigation using two-sample Mendelian randomization analysis. Our goal was to determine if there’s a causal relationship between high vitamin D levels and the risk of experiencing headaches.
Our findings revealed that higher levels of vitamin D are linked to a lower risk of headaches. Specifically, we found that vitamin D may have a preventive effect, reducing the likelihood of headaches occurring. However, we also observed that there is no evidence to suggest that headaches cause changes in vitamin D levels.
This means while supplementing vitamin D may help keep headaches at bay, headaches themselves do not appear to affect vitamin D levels. This information contributes valuable insights into how maintaining sufficient vitamin D could play a role in headache management.
Our findings revealed that higher levels of vitamin D are linked to a lower risk of headaches. Specifically, we found that vitamin D may have a preventive effect, reducing the likelihood of headaches occurring. However, we also observed that there is no evidence to suggest that headaches cause changes in vitamin D levels.
This means while supplementing vitamin D may help keep headaches at bay, headaches themselves do not appear to affect vitamin D levels. This information contributes valuable insights into how maintaining sufficient vitamin D could play a role in headache management.
8
We aimed to investigate how vitamin D levels might impact migraine occurrences in children. Recent research highlighted that many youngsters experience migraines, and intriguingly, vitamin D has been linked to various neurological conditions.
In diving into existing literature, we found a noteworthy connection between low vitamin D levels and the frequency and duration of migraine attacks in pediatric patients. Our review suggested that vitamin D supplementation could potentially enhance the quality of life for those suffering from migrainous headaches.
While vitamin D is often talked about in terms of its benefits for bone health, its implications for migraine management in children seem promising. We recognized the potential for vitamin D to play a meaningful role in alleviating headaches, especially in a time when many children face this debilitating condition.
In diving into existing literature, we found a noteworthy connection between low vitamin D levels and the frequency and duration of migraine attacks in pediatric patients. Our review suggested that vitamin D supplementation could potentially enhance the quality of life for those suffering from migrainous headaches.
While vitamin D is often talked about in terms of its benefits for bone health, its implications for migraine management in children seem promising. We recognized the potential for vitamin D to play a meaningful role in alleviating headaches, especially in a time when many children face this debilitating condition.
7
We aimed to explore the relationship between vitamin D levels and migraine prevalence, using data from over 9,100 participants in the National Health and Nutrition Examination Survey conducted between 2001 and 2004. Our focus was on how serum vitamin D, specifically 25OHD2 and 25OHD3, might impact headache occurrences.
Our findings indicated that about 20.5% of the adults we studied reported experiencing migraines. Notably, those with lower levels of vitamin D were more likely to suffer from migraines. In fact, participants in the highest quartile of vitamin D levels had a 16% lower likelihood of experiencing migraines compared to those in the lowest quartile. This was confirmed through various analytical methods, including logistic regression and stratified analysis.
While the results suggest a significant negative correlation between vitamin D levels and migraine prevalence, it’s important to remember that this study does not directly address whether vitamin D treatment could alleviate headaches. Rather, it highlights the need for further research to understand the role of vitamin D in migraine development.
Our findings indicated that about 20.5% of the adults we studied reported experiencing migraines. Notably, those with lower levels of vitamin D were more likely to suffer from migraines. In fact, participants in the highest quartile of vitamin D levels had a 16% lower likelihood of experiencing migraines compared to those in the lowest quartile. This was confirmed through various analytical methods, including logistic regression and stratified analysis.
While the results suggest a significant negative correlation between vitamin D levels and migraine prevalence, it’s important to remember that this study does not directly address whether vitamin D treatment could alleviate headaches. Rather, it highlights the need for further research to understand the role of vitamin D in migraine development.
User Reviews
USERS' SCORE
Good
Based on 4 Reviews
8.5
- All Reviews
- Positive Reviews
- Negative Reviews
9
No more headaches
Good composition, fast delivery, and high-quality packaging. The capsules are a tad large but easy to swallow and taste citrusy. I've taken one daily for ten days, along with other supplements. I’ve noticed significant benefits; headaches have ceased, fatigue has reduced, and my mood has improved greatly. I highly recommend it for those interested in sports, fitness, or dieting, as omega-3 energises and replenishes the body effectively.
9
Headaches gone
All is well; I feel good. This supplement lasts a long time for the price, and I've noticed my headaches have disappeared, leaving me feeling lighter.
9
No side effects
Some vitamin D brands cause headaches, but this one has no side effects for me.
7.5
Less frequent headaches
A great product for the price. During winter in Siberia, it’s essential. I take one capsule each morning with breakfast, which helps me feel more energetic, and my headaches after work are less frequent. With good sleep, I feel fantastic compared to my previous state of fatigue and apathy.
Frequently Asked Questions
9
No more headaches
Good composition, fast delivery, and high-quality packaging. The capsules are a tad large but easy to swallow and taste citrusy. I've taken one daily for ten days, along with other supplements. I’ve noticed significant benefits; headaches have ceased, fatigue has reduced, and my mood has improved greatly. I highly recommend it for those interested in sports, fitness, or dieting, as omega-3 energises and replenishes the body effectively.
9
Headaches gone
All is well; I feel good. This supplement lasts a long time for the price, and I've noticed my headaches have disappeared, leaving me feeling lighter.
7.5
Less frequent headaches
A great product for the price. During winter in Siberia, it’s essential. I take one capsule each morning with breakfast, which helps me feel more energetic, and my headaches after work are less frequent. With good sleep, I feel fantastic compared to my previous state of fatigue and apathy.
9
No side effects
Some vitamin D brands cause headaches, but this one has no side effects for me.
7
We aimed to explore the relationship between vitamin D levels and migraine prevalence, using data from over 9,100 participants in the National Health and Nutrition Examination Survey conducted between 2001 and 2004. Our focus was on how serum vitamin D, specifically 25OHD2 and 25OHD3, might impact headache occurrences.
Our findings indicated that about 20.5% of the adults we studied reported experiencing migraines. Notably, those with lower levels of vitamin D were more likely to suffer from migraines. In fact, participants in the highest quartile of vitamin D levels had a 16% lower likelihood of experiencing migraines compared to those in the lowest quartile. This was confirmed through various analytical methods, including logistic regression and stratified analysis.
While the results suggest a significant negative correlation between vitamin D levels and migraine prevalence, it’s important to remember that this study does not directly address whether vitamin D treatment could alleviate headaches. Rather, it highlights the need for further research to understand the role of vitamin D in migraine development.
Our findings indicated that about 20.5% of the adults we studied reported experiencing migraines. Notably, those with lower levels of vitamin D were more likely to suffer from migraines. In fact, participants in the highest quartile of vitamin D levels had a 16% lower likelihood of experiencing migraines compared to those in the lowest quartile. This was confirmed through various analytical methods, including logistic regression and stratified analysis.
While the results suggest a significant negative correlation between vitamin D levels and migraine prevalence, it’s important to remember that this study does not directly address whether vitamin D treatment could alleviate headaches. Rather, it highlights the need for further research to understand the role of vitamin D in migraine development.
8
Combined treatment benefits migraines
We conducted a randomized, triple-blinded, placebo-controlled trial focusing on the effects of vitamin D and probiotic co-supplementation on migraine headaches. This study included adult patients aged 18 to 55 diagnosed with migraines, specifically using the International Classification of Headache Disorders-3 criteria.
Over a 12-week period, participants received either 50,000 IU of vitamin D plus a daily probiotic or a placebo. We assessed their migraine symptoms through reliable questionnaires and self-reported diaries, tracking headache frequency, duration, and intensity. We also measured their mental health, daily functioning, and inflammation markers during the trial.
Our findings indicated that the combination of vitamin D and probiotics provided beneficial effects on migraine characteristics, including improved mental health outcomes. Although we did not isolate the impact of vitamin D alone, the results suggest that it may play a role in migraine management when paired with probiotics. Further studies are needed to firmly establish these effects and better understand the potential of vitamin D as a treatment option for headaches.
Over a 12-week period, participants received either 50,000 IU of vitamin D plus a daily probiotic or a placebo. We assessed their migraine symptoms through reliable questionnaires and self-reported diaries, tracking headache frequency, duration, and intensity. We also measured their mental health, daily functioning, and inflammation markers during the trial.
Our findings indicated that the combination of vitamin D and probiotics provided beneficial effects on migraine characteristics, including improved mental health outcomes. Although we did not isolate the impact of vitamin D alone, the results suggest that it may play a role in migraine management when paired with probiotics. Further studies are needed to firmly establish these effects and better understand the potential of vitamin D as a treatment option for headaches.
7
We examined the connection between vitamin D and headaches, particularly in children and adolescents. Although studies show a potential benefit of vitamin D supplementation, the overall effectiveness in reducing headaches isn't conclusively proven.
The research indicated that dietary supplements like vitamin D might have specific effects on lowering headache frequency or severity. However, they are often assessed alongside other treatments, such as physiotherapy or acupuncture, making it difficult to isolate their impact.
Overall, while incorporating vitamin D may be beneficial for some, we should remain cautious and not regard it as a standalone solution for headache relief.
The research indicated that dietary supplements like vitamin D might have specific effects on lowering headache frequency or severity. However, they are often assessed alongside other treatments, such as physiotherapy or acupuncture, making it difficult to isolate their impact.
Overall, while incorporating vitamin D may be beneficial for some, we should remain cautious and not regard it as a standalone solution for headache relief.
9
We conducted a clinical trial to investigate the effects of vitamin D supplementation alongside topiramate, a medication commonly used for migraine prevention in children aged 5 to 14. In this double-blind study, participants were divided into two groups: one received vitamin D with their topiramate treatment, while the other received a placebo.
After four months, we observed that those who took vitamin D experienced a significant reduction in the monthly frequency of headache attacks compared to the placebo group. We noted that children taking vitamin D also reported less disability from their migraines and a higher percentage showed a good response to the treatment.
Furthermore, the side effects were relatively similar between both groups, suggesting that combining vitamin D with topiramate is a safe and well-tolerated option. Overall, our findings indicate that vitamin D supplementation could enhance migraine management in pediatric patients.
After four months, we observed that those who took vitamin D experienced a significant reduction in the monthly frequency of headache attacks compared to the placebo group. We noted that children taking vitamin D also reported less disability from their migraines and a higher percentage showed a good response to the treatment.
Furthermore, the side effects were relatively similar between both groups, suggesting that combining vitamin D with topiramate is a safe and well-tolerated option. Overall, our findings indicate that vitamin D supplementation could enhance migraine management in pediatric patients.
References
- Hao S, Qian R, Chen Y, Liu J, Xu X, et al. Association between serum vitamin D and severe headache or migraine: A population-based analysis. PLoS One. 2025;20:e0313082. doi:10.1371/journal.pone.0313082
- Tirani SA, Khorvash F, Saneei P, Moradmand Z, Askari G. Effects of probiotic and vitamin D co-supplementation on clinical symptoms, mental health, and inflammation in adult patients with migraine headache: a randomized, triple-blinded, placebo-controlled trial. BMC Med. 2024;22:457. doi:10.1186/s12916-024-03684-6
- Xiong H, Jiang R, Xing L, Zheng J, Tian X, et al. New evidence that vitamin D prevents headache: a bidirectional two-sample Mendelian randomization analysis. Front Neurol. 2024;15:1423569. doi:10.3389/fneur.2024.1423569
- Ioannidou E, Tsakiris C, Goulis DG, Christoforidis A, Zafeiriou D. The association of serum vitamin D concentrations in paediatric migraine. Eur J Paediatr Neurol. 2023;47:60. doi:10.1016/j.ejpn.2023.09.007
- Das S, Roy A, Behera SK, Selvarajan S, Kamalanathan S, et al. Effects of Vitamin D on Migraine: A Meta-Analysis. Neurol India. 2023;71:655. doi:10.4103/0028-3886.383862
- Gaul C, Zaranek L, Goßrau G. [Complementary and supplementary procedures in the treatment of headache]. Schmerz. 2023;37:448. doi:10.1007/s00482-023-00738-1
- Kotb Elmala M, Suliman HA, Al-Shokary AH, Ibrahim AO, Kamal NM, et al. The Impact of Vitamin D Supplementation to Topiramate Therapy on Pediatric Migraine Prophylaxis. J Child Neurol. 2022;37:833. doi:10.1177/08830738221092882
