' 
SCIENTIFIC SCORE
Most Likely Effective
Based on 12 Researches
7.7
USERS' SCORE
Very Good
Based on 1 Reviews
8.8
Supplement Facts
Serving Size: 1 Softgel
Amount Per Serving
%DV
Vitamin D (as D3 Cholecalciferol)
125 mcg (5,000 IU)
625%
Top Medical Research Studies
9.5
Vitamin D may alleviate chronic hives
Vitamin D treatment for chronic urticaria: a case report.
Directly addresses vitamin D effects
We explored the intriguing connection between vitamin D and chronic hives, also known as chronic urticaria. This condition involves recurring itchy welts that can be quite frustrating, especially when the triggers are often elusive. In this case, we observed a 14-year-old boy suffering from persistent hives that weren’t responding to conventional treatments. Thankfully, during his medical evaluation, we discovered he had a vitamin D deficiency.
The boy underwent high-dose vitamin D replenishment, which led to a remarkable and swift improvement in his symptoms. This incident raises an important question about the potential role of vitamin D in both the development and treatment of chronic urticaria. While there’s some evidence suggesting a linked relationship, measuring vitamin D levels and providing supplementation aren’t standard practices in diagnosing or treating this condition yet.
Although our findings indicate that vitamin D might help some patients, we remain cautious about recommending routine screening for vitamin D deficiency in those with chronic urticaria. More research is needed to determine how cost-effective such screenings would be for this condition. Overall, this case sheds light on the possibility that vitamin D could play a significant role in managing chronic hives for certain individuals.
The boy underwent high-dose vitamin D replenishment, which led to a remarkable and swift improvement in his symptoms. This incident raises an important question about the potential role of vitamin D in both the development and treatment of chronic urticaria. While there’s some evidence suggesting a linked relationship, measuring vitamin D levels and providing supplementation aren’t standard practices in diagnosing or treating this condition yet.
Although our findings indicate that vitamin D might help some patients, we remain cautious about recommending routine screening for vitamin D deficiency in those with chronic urticaria. More research is needed to determine how cost-effective such screenings would be for this condition. Overall, this case sheds light on the possibility that vitamin D could play a significant role in managing chronic hives for certain individuals.
Read More
8
Vitamin D improves hives symptoms
Effects of Serum Vitamin D Levels and Vitamin D Supplementation on Urticaria: A Systematic Review and Meta-Analysis.
Directly assesses vitamin D effects
We conducted a comprehensive review to understand how vitamin D affects hives (urticaria) and its role in improving symptoms. Our analysis included a number of studies that compared vitamin D levels in people with hives to those without, as well as some clinical trials focusing on vitamin D supplementation.
Through our evaluation, we discovered that individuals with hives, especially those suffering from chronic conditions, tend to have lower serum levels of 25-hydroxyvitamin D. Specifically, the difference was about 9.35 ng/mL lower in the urticaria group compared to the control group.
Moreover, we found encouraging evidence from vitamin D supplementation trials. In six trials, those who received vitamin D treatment showed a notable reduction in their hives symptoms, with a mean reduction in clinical scores of approximately 3.63 in randomized control studies and 1.54 in repeated measure trials.
Overall, it seems that vitamin D deficiency may be a risk factor for hives, and supplementation could potentially lead to significant improvements in symptoms for affected individuals.
Through our evaluation, we discovered that individuals with hives, especially those suffering from chronic conditions, tend to have lower serum levels of 25-hydroxyvitamin D. Specifically, the difference was about 9.35 ng/mL lower in the urticaria group compared to the control group.
Moreover, we found encouraging evidence from vitamin D supplementation trials. In six trials, those who received vitamin D treatment showed a notable reduction in their hives symptoms, with a mean reduction in clinical scores of approximately 3.63 in randomized control studies and 1.54 in repeated measure trials.
Overall, it seems that vitamin D deficiency may be a risk factor for hives, and supplementation could potentially lead to significant improvements in symptoms for affected individuals.
Read More
8
Vitamin D reduces chronic hives severity
Effect of vitamin D supplementation on clinical outcome and biochemical profile in South Indian population with vitamin D-deficient chronic urticarial - A randomized double-blind placebo controlled trial.
Highly relevant to vitamin D research
We conducted a study to examine the effect of vitamin D supplementation on patients suffering from chronic hives, also known as chronic urticaria (CU). Over the course of 12 weeks, we enrolled 120 participants who had low levels of vitamin D and provided them with a dose of 60,000 IU of vitamin D every two weeks.
To ensure accuracy, we compared the results to a control group receiving a placebo. We assessed the severity of the hives using the Urticaria Activity Score (UAS7) and also evaluated inflammatory markers in the blood before and after the treatment.
At the end of the study, we observed that those who received vitamin D showed a significant reduction in UAS7 scores, indicating less severe hives compared to the placebo group. Furthermore, our measurements of inflammatory cytokines revealed that vitamin D treatment also helped lower inflammation in these patients.
Overall, our findings suggest that vitamin D supplementation can be an effective strategy to reduce the severity of chronic urticaria, likely by helping to decrease systemic inflammation associated with the condition.
To ensure accuracy, we compared the results to a control group receiving a placebo. We assessed the severity of the hives using the Urticaria Activity Score (UAS7) and also evaluated inflammatory markers in the blood before and after the treatment.
At the end of the study, we observed that those who received vitamin D showed a significant reduction in UAS7 scores, indicating less severe hives compared to the placebo group. Furthermore, our measurements of inflammatory cytokines revealed that vitamin D treatment also helped lower inflammation in these patients.
Overall, our findings suggest that vitamin D supplementation can be an effective strategy to reduce the severity of chronic urticaria, likely by helping to decrease systemic inflammation associated with the condition.
Read More
Most Useful Reviews
8.8
No hives experienced
I take various brands of vitamin D, and I like this one. It does not cause hives for me, and the dosage is ideal for my area.
Read More
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Medical Researches
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Most Likely Effective
Based on 12 Researches
7.7
9.5
Vitamin D may alleviate chronic hives
Vitamin D treatment for chronic urticaria: a case report.
Directly addresses vitamin D effects
We explored the intriguing connection between vitamin D and chronic hives, also known as chronic urticaria. This condition involves recurring itchy welts that can be quite frustrating, especially when the triggers are often elusive. In this case, we observed a 14-year-old boy suffering from persistent hives that weren’t responding to conventional treatments. Thankfully, during his medical evaluation, we discovered he had a vitamin D deficiency.
The boy underwent high-dose vitamin D replenishment, which led to a remarkable and swift improvement in his symptoms. This incident raises an important question about the potential role of vitamin D in both the development and treatment of chronic urticaria. While there’s some evidence suggesting a linked relationship, measuring vitamin D levels and providing supplementation aren’t standard practices in diagnosing or treating this condition yet.
Although our findings indicate that vitamin D might help some patients, we remain cautious about recommending routine screening for vitamin D deficiency in those with chronic urticaria. More research is needed to determine how cost-effective such screenings would be for this condition. Overall, this case sheds light on the possibility that vitamin D could play a significant role in managing chronic hives for certain individuals.
The boy underwent high-dose vitamin D replenishment, which led to a remarkable and swift improvement in his symptoms. This incident raises an important question about the potential role of vitamin D in both the development and treatment of chronic urticaria. While there’s some evidence suggesting a linked relationship, measuring vitamin D levels and providing supplementation aren’t standard practices in diagnosing or treating this condition yet.
Although our findings indicate that vitamin D might help some patients, we remain cautious about recommending routine screening for vitamin D deficiency in those with chronic urticaria. More research is needed to determine how cost-effective such screenings would be for this condition. Overall, this case sheds light on the possibility that vitamin D could play a significant role in managing chronic hives for certain individuals.
Read More
9
Vitamin D helps improve hives
The effect of vitamin D add-on therapy on the improvement of quality of life and clinical symptoms of patients with chronic spontaneous urticaria.
Study evaluates vitamin D effectiveness
We conducted a detailed study to understand how vitamin D might improve the lives of those suffering from chronic spontaneous urticaria, commonly known as hives. In our research, we randomly assigned 80 participants to two groups: one receiving a lower dose of vitamin D (4200 IU/week) and the other a higher dose (28,000 IU/week) over 12 weeks.
We measured various factors including participants' quality of life, the severity of their hives, and levels of vitamin D in their blood. Our findings revealed that both groups experienced a significant decrease in the severity of hives over the 12 weeks. Interestingly, those who received the higher dose of vitamin D saw even more notable improvements, particularly at the 6 and 12-week marks.
Additionally, quality of life ratings improved more substantially in the high-dose group compared to the lower-dose group. While the medication scores dropped for both groups, there wasn't a significant difference between them. Overall, we found that taking vitamin D, especially at higher doses, could be a safe and effective way to help manage the distress of hives and enhance overall well-being.
We measured various factors including participants' quality of life, the severity of their hives, and levels of vitamin D in their blood. Our findings revealed that both groups experienced a significant decrease in the severity of hives over the 12 weeks. Interestingly, those who received the higher dose of vitamin D saw even more notable improvements, particularly at the 6 and 12-week marks.
Additionally, quality of life ratings improved more substantially in the high-dose group compared to the lower-dose group. While the medication scores dropped for both groups, there wasn't a significant difference between them. Overall, we found that taking vitamin D, especially at higher doses, could be a safe and effective way to help manage the distress of hives and enhance overall well-being.
Read More
8
Vitamin D improves hives symptoms
Effects of Serum Vitamin D Levels and Vitamin D Supplementation on Urticaria: A Systematic Review and Meta-Analysis.
Directly assesses vitamin D effects
We conducted a comprehensive review to understand how vitamin D affects hives (urticaria) and its role in improving symptoms. Our analysis included a number of studies that compared vitamin D levels in people with hives to those without, as well as some clinical trials focusing on vitamin D supplementation.
Through our evaluation, we discovered that individuals with hives, especially those suffering from chronic conditions, tend to have lower serum levels of 25-hydroxyvitamin D. Specifically, the difference was about 9.35 ng/mL lower in the urticaria group compared to the control group.
Moreover, we found encouraging evidence from vitamin D supplementation trials. In six trials, those who received vitamin D treatment showed a notable reduction in their hives symptoms, with a mean reduction in clinical scores of approximately 3.63 in randomized control studies and 1.54 in repeated measure trials.
Overall, it seems that vitamin D deficiency may be a risk factor for hives, and supplementation could potentially lead to significant improvements in symptoms for affected individuals.
Through our evaluation, we discovered that individuals with hives, especially those suffering from chronic conditions, tend to have lower serum levels of 25-hydroxyvitamin D. Specifically, the difference was about 9.35 ng/mL lower in the urticaria group compared to the control group.
Moreover, we found encouraging evidence from vitamin D supplementation trials. In six trials, those who received vitamin D treatment showed a notable reduction in their hives symptoms, with a mean reduction in clinical scores of approximately 3.63 in randomized control studies and 1.54 in repeated measure trials.
Overall, it seems that vitamin D deficiency may be a risk factor for hives, and supplementation could potentially lead to significant improvements in symptoms for affected individuals.
Read More
8
Vitamin D reduces chronic hives severity
Effect of vitamin D supplementation on clinical outcome and biochemical profile in South Indian population with vitamin D-deficient chronic urticarial - A randomized double-blind placebo controlled trial.
Highly relevant to vitamin D research
We conducted a study to examine the effect of vitamin D supplementation on patients suffering from chronic hives, also known as chronic urticaria (CU). Over the course of 12 weeks, we enrolled 120 participants who had low levels of vitamin D and provided them with a dose of 60,000 IU of vitamin D every two weeks.
To ensure accuracy, we compared the results to a control group receiving a placebo. We assessed the severity of the hives using the Urticaria Activity Score (UAS7) and also evaluated inflammatory markers in the blood before and after the treatment.
At the end of the study, we observed that those who received vitamin D showed a significant reduction in UAS7 scores, indicating less severe hives compared to the placebo group. Furthermore, our measurements of inflammatory cytokines revealed that vitamin D treatment also helped lower inflammation in these patients.
Overall, our findings suggest that vitamin D supplementation can be an effective strategy to reduce the severity of chronic urticaria, likely by helping to decrease systemic inflammation associated with the condition.
To ensure accuracy, we compared the results to a control group receiving a placebo. We assessed the severity of the hives using the Urticaria Activity Score (UAS7) and also evaluated inflammatory markers in the blood before and after the treatment.
At the end of the study, we observed that those who received vitamin D showed a significant reduction in UAS7 scores, indicating less severe hives compared to the placebo group. Furthermore, our measurements of inflammatory cytokines revealed that vitamin D treatment also helped lower inflammation in these patients.
Overall, our findings suggest that vitamin D supplementation can be an effective strategy to reduce the severity of chronic urticaria, likely by helping to decrease systemic inflammation associated with the condition.
Read More
8
Mizolastine and proteoglycan effective
Effects of combination of mizolastine and proteoglycan on chronic urticaria: a randomized controlled trial.
Nutritive role of vitamin D
In our exploration of chronic urticaria, we discovered how a combination treatment involving mizolastine, proteoglycan, and vitamin D can be effective. The study included a randomized design with two groups: one receiving the full treatment and the other receiving the same regimen minus proteoglycan. Over four weeks, we observed that those in the treatment group experienced a significant improvement in their symptoms. Specifically, 44 out of 56 patients showed a decline in symptoms by over 60% compared to just 24 out of 44 in the control group.
Alongside these findings, we noted a lower relapse rate for the treatment group after two months, dropping to 17.9% compared to 38.6% for the control group. Importantly, the levels of a key immune marker, IFN-γ, were higher in the group that received proteoglycan, suggesting it plays a role in enhancing the effectiveness of the treatment. While vitamin D was part of the overall protocol, separating its specific contributions is challenging due to the combined treatment nature.
Overall, our findings suggest that while vitamin D was included in the regimen, the stronger efficacy came from the combination with mizolastine and proteoglycan. This highlights the need for further studies focusing on the isolated impacts of vitamin D on hives to really understand its role more precisely.
Alongside these findings, we noted a lower relapse rate for the treatment group after two months, dropping to 17.9% compared to 38.6% for the control group. Importantly, the levels of a key immune marker, IFN-γ, were higher in the group that received proteoglycan, suggesting it plays a role in enhancing the effectiveness of the treatment. While vitamin D was part of the overall protocol, separating its specific contributions is challenging due to the combined treatment nature.
Overall, our findings suggest that while vitamin D was included in the regimen, the stronger efficacy came from the combination with mizolastine and proteoglycan. This highlights the need for further studies focusing on the isolated impacts of vitamin D on hives to really understand its role more precisely.
Read More
User Reviews
USERS' SCORE
Very Good
Based on 1 Reviews
8.8
8.8
No hives experienced
I take various brands of vitamin D, and I like this one. It does not cause hives for me, and the dosage is ideal for my area.
