I'm 47 and work in the health care field and have been taking 4 simultaneous bp medicines for resistant hypertension for over 15 years. A little over a year ago, I developed tinnitus which I presumed to be a side effect of one or more of the medicines I was taking, and have been through an extensive workup to find out whether I have secondary hypertension and/or whether my drug regimen could be simplified. While researching tinnitus treatment, I came across an article that linked treating tinnitus in those with low CoQ10 levels with possible causes of low CoQ10 including medications like beta blockers and statins, as well as aging and other causes. I've been on beta blockers for over 15 years. A couple weeks after starting Ubiquinol, I noticed my blood pressure was so much better (even with nighttime blood pressure spikes) that I was able to discontinue my calcium channel blocker. I also noticed that I was able to do my daily swimming workouts for significantly longer distances without muscle aches (currently, swimming 1 mile nonstop). A month later, I was able (or rather needed to) stop my beta blocker also because my pulse dropped into the high 40's/min and my bp fell to the 90/60 range. Please note that 6 months ago, I found that eating watermelon (contains a high concentration of the amino acid L-citrulline which, when metabolized, produces nitric oxide) also helped my bp and I have been eating that every day since. However, I had a profound bp drop when adding Ubiquinol. I do highly recommend discussing with your health care professional if you consider taking CoQ10/Ubiquinol and only decrease or stop taking your meds under his or her direction. In addition he/she may wish to check your CoQ10 blood level before starting the supplement