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Supplement Facts
Serving Size: 2 capsules
Amount Per Serving
%DV
Aged Garlic Extract™†† Powder (bulb)
1200 mg
**
The product is found useful for the following medical conditions
Cold details
SCIENTIFIC SCORE
Moderately Effective
Based on 3 Researches
8.7
USERS' SCORE
Good
Based on 4 Reviews
8.7
9
Efficacy of garlic against colds
Interventions for preventing influenza: An overview of Cochrane systematic reviews and a Bayesian network meta-analysis.
Most Relevant Research
We examined the effectiveness of garlic as a treatment to prevent cold symptoms based on a comprehensive review of systematic reviews. This analysis included various studies that compared garlic and other preventative interventions against a control group receiving no treatment or a placebo.
Our findings indicated that garlic demonstrated notable advantages in reducing instances of influenza, a key player in the spectrum of cold-like illnesses. However, we also learned that the evidence surrounding garlic specifically for cold prevention isn't robust enough to make definitive claims.
It's essential to note that while garlic showed potential, vitamin C did not present any significant benefits in this context. Ultimately, the effectiveness of other interventions remains to be convincingly validated with strong scientific evidence.
Our findings indicated that garlic demonstrated notable advantages in reducing instances of influenza, a key player in the spectrum of cold-like illnesses. However, we also learned that the evidence surrounding garlic specifically for cold prevention isn't robust enough to make definitive claims.
It's essential to note that while garlic showed potential, vitamin C did not present any significant benefits in this context. Ultimately, the effectiveness of other interventions remains to be convincingly validated with strong scientific evidence.
9.5
Excellent cold prevention
Most Useful Review
Best garlic supplement. After trying several, I return to this one due to its lack of taste or smell, and I can tell it works best for my body and immunity. I use it as a preventative for cold/flu and haven't been sick in three years. Combined with Vitamin C and B Complex, plus powdered Colostrum during cold seasons, I recently felt a flu coming and took 2 pills three times a day, and it was gone within 3 days. I never progressed beyond the initial "I'm getting sick" feeling.
Ear Infection details
SCIENTIFIC SCORE
Moderately Effective
Based on 3 Researches
8.3
USERS' SCORE
Good
Based on 2 Reviews
8.7
8
Garlic shows promise against infections
Antimicrobial Activity of Garlic Derivatives on Common Causative Microorganisms of the External Ear Canal and Chronic Middle Ear Infections.
Most Relevant Research
We set out to investigate the potential of garlic derivatives as an alternative treatment for ear infections. With antibiotic resistance on the rise, finding new ways to combat these infections has become increasingly crucial.
Our study focused on the antimicrobial properties of four garlic compounds: allicin, s-allyl cysteine (SAC), diallyl disulfide (DADS), and s-allyl mercaptocysteine (SAMC). By using the broth microdilution method, we tested how effectively these compounds could inhibit the growth of bacteria and yeasts that commonly cause ear infections.
We were excited to find that both allicin and SAC demonstrated impressive antimicrobial activity, even at low concentrations. This opens up the possibility that these garlic derivatives could be used in the future to treat infections in the ear. However, DADS and SAMC showed considerably less effectiveness, particularly SAMC, which did not showcase any significant impact against the tested microorganisms.
Overall, our findings suggest that garlic derivatives, particularly allicin and SAC, could represent a promising direction in the search for new treatments for ear infections.
Our study focused on the antimicrobial properties of four garlic compounds: allicin, s-allyl cysteine (SAC), diallyl disulfide (DADS), and s-allyl mercaptocysteine (SAMC). By using the broth microdilution method, we tested how effectively these compounds could inhibit the growth of bacteria and yeasts that commonly cause ear infections.
We were excited to find that both allicin and SAC demonstrated impressive antimicrobial activity, even at low concentrations. This opens up the possibility that these garlic derivatives could be used in the future to treat infections in the ear. However, DADS and SAMC showed considerably less effectiveness, particularly SAMC, which did not showcase any significant impact against the tested microorganisms.
Overall, our findings suggest that garlic derivatives, particularly allicin and SAC, could represent a promising direction in the search for new treatments for ear infections.
9.5
Sinus infection relief
Most Useful Review
Amazing sinus infection relief! I had been taking Kyolic garlic products on and off but got a horrible sinus infection from a mould allergy on vacation. After trying various natural remedies to no avail, I turned to Kyolic Reserve. After one tablet, my head started to clear, and I even felt my ear pop while sleeping. I continued to improve after taking a few more doses. I'm elated to find such a powerful natural antibiotic; my sinus infection has cleared!
Common Cold details
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 15 Reviews
8.6
9.5
Strengthened immune system
Most Useful Review
Garlic contains sulfur compounds which positively affect cardiovascular health and inflammation. I purchased this supplement for my father, who had persistent coughs during flu season. After a month of taking it, his immune system improved significantly, and he no longer suffers from severe coughing when catching a cold.
Heart Attack details
SCIENTIFIC SCORE
Moderately Effective
Based on 2 Researches
8.5
USERS' SCORE
Good
Based on 11 Reviews
8.6
8
Garlic's allicin aids heart recovery
Metagenomic Sequencing Combined with Metabolomics to Explore Gut Microbiota and Metabolic Changes in Mice with Acute Myocardial Infarction and the Potential Mechanism of Allicin.
Most Relevant Research
We induced acute myocardial infarction (AMI) in mice to investigate the impact of allicin, a key component of garlic, on heart health. Over 28 days, we administered allicin orally while monitoring various factors such as heart function and inflammation through echocardiography and other tests.
Our findings revealed that allicin significantly eased myocardial injury, reducing markers of inflammation and improving heart function. It did this by inhibiting certain pathways associated with inflammation and remodeling gut microbiota, which plays a role in overall health.
Essentially, we found that allicin not only supports heart recovery but also enhances intestinal barrier health and improves metabolic balance. This discovery opens up exciting avenues for allicin to be considered as a supplementary treatment alongside conventional therapies for heart attacks.
Our findings revealed that allicin significantly eased myocardial injury, reducing markers of inflammation and improving heart function. It did this by inhibiting certain pathways associated with inflammation and remodeling gut microbiota, which plays a role in overall health.
Essentially, we found that allicin not only supports heart recovery but also enhances intestinal barrier health and improves metabolic balance. This discovery opens up exciting avenues for allicin to be considered as a supplementary treatment alongside conventional therapies for heart attacks.
8.3
Prevention evidence
Most Useful Review
Dr Matthew Budoff’s study showed that Kyolic garlic extract can prevent heart attack by reducing arterial plaque accumulation. Patients taking the extract showed a decrease in plaque, while the placebo group saw an increase. He recommends 1200 mg daily for heart health, highlighting its effectiveness in lowering homocysteine levels, a heart disease marker.
Arthritis details
SCIENTIFIC SCORE
Moderately Effective
Based on 4 Researches
8.3
USERS' SCORE
Good
Based on 1 Review
8.6
9
Garlic exosomes benefit osteoarthritis
Garlic-derived Exosomes Alleviate Osteoarthritis Through Inhibiting the MAPK Signaling Pathway.
Most Relevant Research
In our exploration of garlic's potential benefits for arthritis, we focused on a type of tiny particle called garlic-derived exosomes (GDEs). These particles come from garlic and have shown promise in reducing inflammation in various health issues. We specifically examined how they affect osteoarthritis (OA), a condition that impacts millions by causing joint pain and stiffness.
Our study involved both laboratory and animal models. We treated chondrocytes, the cells in cartilage, with a pro-inflammatory substance while exposing them to GDEs. We found that the garlic-derived particles helped to boost the levels of beneficial cartilage components while inhibiting harmful enzymes that break down cartilage. Additionally, GDEs appeared to reduce the activity of key signaling pathways related to inflammation.
On the animal side, we used a surgical model to simulate OA and injected GDEs directly into the knee joints of mice. The results were encouraging; the GDEs alleviated pain and improved how the mice moved. Histological examinations revealed less joint destruction, suggesting that these garlic particles could indeed help slow the progression of OA without causing toxicity.
Overall, our findings indicate that garlic-derived exosomes hold potential as a treatment for osteoarthritis, making it a significant area for future research into disease-modifying therapies.
Our study involved both laboratory and animal models. We treated chondrocytes, the cells in cartilage, with a pro-inflammatory substance while exposing them to GDEs. We found that the garlic-derived particles helped to boost the levels of beneficial cartilage components while inhibiting harmful enzymes that break down cartilage. Additionally, GDEs appeared to reduce the activity of key signaling pathways related to inflammation.
On the animal side, we used a surgical model to simulate OA and injected GDEs directly into the knee joints of mice. The results were encouraging; the GDEs alleviated pain and improved how the mice moved. Histological examinations revealed less joint destruction, suggesting that these garlic particles could indeed help slow the progression of OA without causing toxicity.
Overall, our findings indicate that garlic-derived exosomes hold potential as a treatment for osteoarthritis, making it a significant area for future research into disease-modifying therapies.
10
Works remarkably
Most Useful Review
Great for arthritis! This product works fantastically for my arthritis.
Flu details
SCIENTIFIC SCORE
Moderately Effective
Based on 4 Researches
8
USERS' SCORE
Good
Based on 2 Reviews
8.6
9
Garlic shows potential against influenza
Antiviral activity of diallyl trisulfide against H9N2 avian influenza virus infection in vitro and in vivo.
Most Relevant Research
We explored the potential benefits of a garlic-derived compound called diallyl trisulfide (DATS) in combating the H9N2 avian influenza virus. This study specifically looked at its antiviral properties both in human cells and in mice to see if it could provide relief from this infection.
In our research, we treated human lung A549 cells and also utilized BABL/c mice to assess DATS’s effectiveness. We applied DATS before and after the infection and measured its impact on viral loads, inflammatory responses, and overall lung health.
The results were promising. Whether given before or after exposure to the virus, DATS treatment reduced viral loads and led to an improved immune response by increasing antiviral gene expression while also decreasing inflammatory cytokines. Similar benefits were observed in infected mice, highlighting less lung inflammation and edema.
Overall, the findings suggest that DATS may offer a novel alternative for treating influenza, specifically the H9N2 strain, showcasing garlic's potential role in managing viral infections.
In our research, we treated human lung A549 cells and also utilized BABL/c mice to assess DATS’s effectiveness. We applied DATS before and after the infection and measured its impact on viral loads, inflammatory responses, and overall lung health.
The results were promising. Whether given before or after exposure to the virus, DATS treatment reduced viral loads and led to an improved immune response by increasing antiviral gene expression while also decreasing inflammatory cytokines. Similar benefits were observed in infected mice, highlighting less lung inflammation and edema.
Overall, the findings suggest that DATS may offer a novel alternative for treating influenza, specifically the H9N2 strain, showcasing garlic's potential role in managing viral infections.
9.5
Preventative effectiveness
Most Useful Review
After trying various garlic supplements, this is my favourite due to its lack of taste and smell. I use it as a preventative measure for cold and flu and haven’t been ill in three years. I took it alongside other vitamins and when feeling unwell, increased my intake, which resolved my symptoms quickly.
Blood Clot details
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 1 Review
8.5
8.8
Immediate ankle relief
Most Useful Review
Excellent! I researched garlic for cardiovascular issues and discovered I have Factor V Leiden, elevating my risk for blood clots. After weeks of ankle swelling, I took this along with Horse Chestnut, and upon waking the next morning, my ankles were normal (I did exceed the recommended dose). The product had no garlicky taste or aftertaste, which I appreciated. I contacted the company about the gelatin, as it often comes from porcine sources; they confirmed it’s kosher and bovine. They should label it explicitly as such.
Cancer details
SCIENTIFIC SCORE
Possibly Effective
Based on 4 Researches
7.5
USERS' SCORE
Good
Based on 1 Review
8.5
9
Garlic's allicin shows anticancer potential
Harnessing Therapeutic Potential of Allicin Against Cancer: An Exploratory Review.
Most Relevant Research
We investigated the effects of allicin, a compound derived from garlic, on various types of cancer. Our literature review pulled input from trustworthy sources, including well-regarded medical databases. The study primarily aimed to assess whether allicin could inhibit cancer cell growth and its broader therapeutic potential.
Through our exploration, we found that allicin shows considerable promise in fighting cancer. Specifically, cell line studies demonstrated that this compound can significantly reduce the growth of cancer cells across different types, including breast, pancreatic, liver, and colorectal cancers. This evidence highlights allicin's potential as an effective treatment option.
We also took a closer look at existing patent statistics and clinical studies to better understand allicin's advantages. The data reinforced that allicin stands out for its various therapeutic properties, making it an important focal point for future cancer research.
Overall, we are excited to share how garlic, through its active compound allicin, can potentially play a role in cancer therapies, showing real hope in the ongoing battle against this disease.
Through our exploration, we found that allicin shows considerable promise in fighting cancer. Specifically, cell line studies demonstrated that this compound can significantly reduce the growth of cancer cells across different types, including breast, pancreatic, liver, and colorectal cancers. This evidence highlights allicin's potential as an effective treatment option.
We also took a closer look at existing patent statistics and clinical studies to better understand allicin's advantages. The data reinforced that allicin stands out for its various therapeutic properties, making it an important focal point for future cancer research.
Overall, we are excited to share how garlic, through its active compound allicin, can potentially play a role in cancer therapies, showing real hope in the ongoing battle against this disease.
8
Prevention of cancer
Most Useful Review
I take it daily as recommended to help maintain bladder cancer at bay. I've just begun using it with no issues and no unpleasant aftertaste. eBay is a great platform for purchase.
Cough details
SCIENTIFIC SCORE
Moderately Effective
Based on 1 Research
8
USERS' SCORE
Good
Based on 1 Review
8.5
8
Garlic use for cough examined
Use of and attitudes towards herbal medicine during the COVID-19 pandemic: A cross-sectional study in Vietnam.
Most Relevant Research
We surveyed how people in Vietnam utilize herbal medicine, including garlic, for common ailments like coughs during the COVID-19 pandemic. The study found that nearly half of the participants used herbal remedies, with garlic being one of the popular choices alongside ginger and honey.
While our findings indicated that many viewed garlic as safe and effective, particularly for treating sore throats, we must point out that the study did not individually assess garlic's specific effects on cough. Instead, it was considered among other herbal options.
Our insights suggest that while garlic is widely used, there’s no clear evidence indicating it’s distinctly effective for coughs on its own. This research contributes to understanding herbal medicine's role in healthcare, especially during challenging times like a pandemic.
While our findings indicated that many viewed garlic as safe and effective, particularly for treating sore throats, we must point out that the study did not individually assess garlic's specific effects on cough. Instead, it was considered among other herbal options.
Our insights suggest that while garlic is widely used, there’s no clear evidence indicating it’s distinctly effective for coughs on its own. This research contributes to understanding herbal medicine's role in healthcare, especially during challenging times like a pandemic.
8.8
Cold and cough improved
Most Useful Review
Feeling Great. I suffer from frequent colds, typically lasting weeks. After trying Kyolic garlic on a friend's recommendation, I found milder symptoms and recovered much quicker, without lingering cough or congestion. I will continue this daily regime for better health.
Heartburn details
SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 1 Review
8.1
4.3
Does not work
Most Useful Review
Heartburn? I wanted this to work, but it gives me heartburn when I take it.
