Brown garlic aids asthma managementBrown garlic: A nutritionally improved garlic with therapeutic value in asthma treatment modulation of S-nitrosothiols.
High relevance to asthma treatment
We examined the effects of brown garlic on asthma treatment, focusing on its nutritional benefits and therapeutic potential. Our research highlighted the differences between brown garlic and the more commonly known fresh and black garlic varieties.
In our study, we discovered that feeding brown garlic to asthmatic mice resulted in lower levels of exhaled nitric oxide (NO), which is a marker of inflammation in asthma. Surprisingly, the blood levels of S-nitrosothiols (SNOs) increased, suggesting possible mechanisms at play in how brown garlic interacts with the body's nitric oxide system.
Notably, lung biopsies from these mice showed less accumulation of eosinophils, which are white blood cells that contribute to asthma symptoms. Furthermore, we observed that the expression of antioxidant genes was higher in mice consuming brown garlic, while pro-inflammatory interleukins—like IL-4, IL-5, IL-6, IL-13, IL-1β, and TNF-α—were significantly reduced compared to those fed fresh and black garlic.
This research provides a promising glimpse into the potential of brown garlic as a support for asthma treatment, suggesting that it may not only improve nutritional intake but also help modulate some of the inflammatory responses associated with the condition.
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