Bioactive compounds with antifungal activity against pathogens isolated from pregnant woman: Gallesia integrifolia (garlic wood) is a promising treatment for vulvovaginal candidiasis.
We investigated the antifungal properties of Gallesia integrifolia, particularly in treating vulvovaginal candidiasis, which affects many pregnant women. This study focused on the plant's leaves and flowers, known for their medicinal uses in folk medicine. By testing different isolates of Candida, the fungi responsible for this infection, we measured the effectiveness of G. integrifolia using a method called broth microdilution.
One of the key findings was that G. integrifolia acted against various Candida species, showing promising results that suggest it could potentially be a natural alternative to traditional antifungal treatments, which sometimes come with negative side effects. We also employed advanced techniques such as gas chromatography to understand the chemical composition of the essential oils in the plant.
Overall, our results indicate that G. integrifolia, particularly its leaves and flowers, could offer a new therapeutic approach for treating vulvovaginal candidiasis, and it brings hope for safer treatments in pregnant women facing this common issue.
Read More
7
Garlic's mixed effects on candidiasis
Garlic alters the expression of putative virulence factor genes SIR2 and ECE1 in vulvovaginal C. albicans isolates.
We explored the effects of garlic on treating vulvovaginal candidiasis, a condition that can cause significant discomfort for many individuals. Recent observations suggested that garlic could be a beneficial alternative treatment, but the varying successes reported by patients raised questions about its effectiveness.
To investigate further, we examined two clinical strains of Candida albicans from patients who had differing experiences with garlic therapy. Our study focused on two key virulence factor genes: SIR2 and ECE1. Using biofilm assays and real-time PCR, we assessed how these strains responded to both fresh garlic extract and pure allicin, the active component found in crushed garlic.
Our findings revealed that all strains showed a decrease in SIR2 expression after treatment with garlic. However, the response of ECE1 was more complex. In strains from patients who did not respond well to garlic, ECE1 was up-regulated, indicating increased expression. Conversely, in the strain from a patient who benefited from garlic therapy, ECE1 was down-regulated.
These results suggest that while garlic has a consistent effect on certain genes like SIR2, its influence on ECE1 can vary based on individual strain characteristics. Therefore, it is essential for future research to consider these differences when evaluating the effectiveness of phytotherapies like garlic in treating candidiasis.
Read More
8
Garlic's potential in candidiasis treatment
Activity of bioactive garlic compounds on the oral microbiome: a literature review.
We explored the potential of garlic, particularly known for its antimicrobial properties, in treating oral candidiasis—a common fungal infection. The research reviewed evidence on how garlic can effectively combat this condition without the side effects typically associated with conventional treatments.
Garlic derivatives showed promise in managing candidiasis by inhibiting the growth of the Candida fungus. Previous studies highlighted successes in using garlic as an alternative to traditional medications, showing the potential for it to be a natural remedy for those suffering from recurrent oral infections.
However, while the findings suggest garlic's efficacy in treating candidiasis, the studies included are not extensive enough to draw definitive conclusions. More rigorous clinical trials are needed to solidify garlic's role in treating this condition.
Overall, the insights gained from the existing literature point towards garlic as a natural alternative worth further investigation. As demand for natural treatments grows, garlic could become a valuable option in the management of oral health issues.
Read More
Most Useful Reviews
9
High-quality extract
1 people found this helpful
Thanks to this extract, my thrush has dissipated. The quality is excellent with a well-selected composition. It’s impossible to consume garlic in such quantities as with this extract. I frequently take this brand and highly recommend it.
Read More
9
Effective against Candida
1 people found this helpful
Excellent! Garlic extract is superb for eliminating Candidiasis. It is also well-sized, has no odour or taste, and serves as a good antibacterial. The packaging is tightly sealed and the ingredients are excellent.
Read More
9
Sickness reduction
Great product. It helps eliminate Candidiasis, and I’ve noticed I’m rarely sick since I began taking garlic.
Bioactive compounds with antifungal activity against pathogens isolated from pregnant woman: Gallesia integrifolia (garlic wood) is a promising treatment for vulvovaginal candidiasis.
We investigated the antifungal properties of Gallesia integrifolia, particularly in treating vulvovaginal candidiasis, which affects many pregnant women. This study focused on the plant's leaves and flowers, known for their medicinal uses in folk medicine. By testing different isolates of Candida, the fungi responsible for this infection, we measured the effectiveness of G. integrifolia using a method called broth microdilution.
One of the key findings was that G. integrifolia acted against various Candida species, showing promising results that suggest it could potentially be a natural alternative to traditional antifungal treatments, which sometimes come with negative side effects. We also employed advanced techniques such as gas chromatography to understand the chemical composition of the essential oils in the plant.
Overall, our results indicate that G. integrifolia, particularly its leaves and flowers, could offer a new therapeutic approach for treating vulvovaginal candidiasis, and it brings hope for safer treatments in pregnant women facing this common issue.
Read More
8
Garlic's potential in candidiasis treatment
Activity of bioactive garlic compounds on the oral microbiome: a literature review.
We explored the potential of garlic, particularly known for its antimicrobial properties, in treating oral candidiasis—a common fungal infection. The research reviewed evidence on how garlic can effectively combat this condition without the side effects typically associated with conventional treatments.
Garlic derivatives showed promise in managing candidiasis by inhibiting the growth of the Candida fungus. Previous studies highlighted successes in using garlic as an alternative to traditional medications, showing the potential for it to be a natural remedy for those suffering from recurrent oral infections.
However, while the findings suggest garlic's efficacy in treating candidiasis, the studies included are not extensive enough to draw definitive conclusions. More rigorous clinical trials are needed to solidify garlic's role in treating this condition.
Overall, the insights gained from the existing literature point towards garlic as a natural alternative worth further investigation. As demand for natural treatments grows, garlic could become a valuable option in the management of oral health issues.
Read More
7
Garlic's mixed effects on candidiasis
Garlic alters the expression of putative virulence factor genes SIR2 and ECE1 in vulvovaginal C. albicans isolates.
We explored the effects of garlic on treating vulvovaginal candidiasis, a condition that can cause significant discomfort for many individuals. Recent observations suggested that garlic could be a beneficial alternative treatment, but the varying successes reported by patients raised questions about its effectiveness.
To investigate further, we examined two clinical strains of Candida albicans from patients who had differing experiences with garlic therapy. Our study focused on two key virulence factor genes: SIR2 and ECE1. Using biofilm assays and real-time PCR, we assessed how these strains responded to both fresh garlic extract and pure allicin, the active component found in crushed garlic.
Our findings revealed that all strains showed a decrease in SIR2 expression after treatment with garlic. However, the response of ECE1 was more complex. In strains from patients who did not respond well to garlic, ECE1 was up-regulated, indicating increased expression. Conversely, in the strain from a patient who benefited from garlic therapy, ECE1 was down-regulated.
These results suggest that while garlic has a consistent effect on certain genes like SIR2, its influence on ECE1 can vary based on individual strain characteristics. Therefore, it is essential for future research to consider these differences when evaluating the effectiveness of phytotherapies like garlic in treating candidiasis.
Read More
User Reviews
USERS' SCORE
Moderately Good
Based on 17 Reviews
7.9
All Reviews
Positive Reviews
Negative Reviews
9
High-quality extract
1 people found this helpful
Thanks to this extract, my thrush has dissipated. The quality is excellent with a well-selected composition. It’s impossible to consume garlic in such quantities as with this extract. I frequently take this brand and highly recommend it.
Read More
9
Effective against Candida
1 people found this helpful
Excellent! Garlic extract is superb for eliminating Candidiasis. It is also well-sized, has no odour or taste, and serves as a good antibacterial. The packaging is tightly sealed and the ingredients are excellent.
Read More
9
Sickness reduction
Great product. It helps eliminate Candidiasis, and I’ve noticed I’m rarely sick since I began taking garlic.
Read More
9
Effective treatment
An excellent remedy. It acts on fungal films. I have personally used it for Candidiasis treatment. There is a noticeable effect!
Read More
7.5
Prevention of candidiasis
1 people found this helpful
I take this for the prevention of candida, combined with other medications, and it works well.
Candidiasis, commonly known as a yeast infection, is an infection caused by the overgrowth of Candida, a type of fungus that naturally occurs in various locations in the body, including the mouth, gut, and vagina. Under normal circumstances, Candida exists in balance with other microorganisms, but factors such as antibiotic use, high sugar diets, and compromised immune systems can disrupt this balance, leading to an overgrowth. This can manifest in various forms, including oral thrush (affecting the mouth), vaginal yeast infections, and invasive candidiasis (which can affect the bloodstream and internal organs).
Symptoms of candidiasis vary depending on the area affected; for example, a vaginal yeast infection can cause itching, burning, and unusual discharge, while oral thrush may lead to white patches in the mouth, soreness, and difficulty swallowing. Treatment typically involves antifungal medications, which can be prescribed or obtained over-the-counter, depending on the severity and type of the infection. To prevent recurrence, it's essential to maintain a healthy diet, manage stress, and practice good hygiene. If you suspect you have candidiasis, particularly in more severe cases, consulting a healthcare provider is recommended for appropriate diagnosis and treatment options.
Garlic, scientifically known as Allium sativum, is a popular culinary ingredient that is renowned for its distinctive flavor and numerous health benefits. Belonging to the onion family, it is closely related to leeks and shallots. Garlic is typically used in various cuisines worldwide, lending its pungent, savory notes to a range of dishes from pasta sauces to roasted meats. Whether consumed raw, sautéed, or roasted, garlic not only enhances the taste of food but is also prized for its potential health properties, including its antimicrobial effects and ability to boost the immune system.
In addition to its culinary uses, garlic is often celebrated in alternative medicine for its health benefits. It is rich in essential nutrients, including vitamins C and B6, manganese, and selenium. Furthermore, research suggests that garlic may help lower blood pressure, improve cholesterol levels, and provide antioxidant effects. When buying garlic, opt for firm, dry bulbs with tight skin and avoid any signs of sprouting or softness. Fresh garlic cloves can easily elevate your cooking game, making them a staple in kitchens around the globe.
Garlic has garnered attention for its potential antifungal properties, particularly in relation to Candida overgrowth, which can lead to candidiasis. Studies suggest that garlic, specifically its active compound allicin, may inhibit the growth of various fungi, including Candida species. This has led to the belief that incorporating garlic into your diet or utilizing garlic supplements could potentially assist in managing candidiasis symptoms by combating the fungal infection. However, it’s important to remember that while garlic may offer some benefits, it should not replace conventional medical treatments recommended by healthcare professionals.
It's also worth noting that individual experiences with garlic can vary widely, and not everyone may see the same results. Including garlic in a balanced diet might be beneficial for overall health; however, relying solely on it for treating candidiasis or any fungal infection could be misleading. As always, it’s advisable to consult with a healthcare provider for a comprehensive treatment plan tailored to your specific needs and conditions.
Based on user reviews, the timeline for seeing results from garlic extract supplementation for Candidiasis can vary. Some users report noticeable improvements in their condition within a week of starting the supplement, citing benefits such as increased energy and mood enhancements alongside a reduction in Candidiasis symptoms (Read Review). Others, however, have indicated that they might need to wait longer, stating that it can take up to 30 days before experiencing definite positive effects (Read Review).
Overall, many users attest to the effectiveness of garlic extract in combating Candidiasis, describing significant relief and improvements in health when used as part of their treatment regimen (Read Review). It’s important to remember, though, that individual results may vary, and combining garlic extract with other treatments could enhance its efficacy in fighting Candidiasis.
Several studies highlight the potential of natural supplements in treating candidiasis, particularly focusing on garlic and Gallesia integrifolia. Research on Gallesia integrifolia, for instance, demonstrates its antifungal properties, particularly against vulvovaginal candidiasis, which is especially relevant for pregnant women. This study showed that extracts from the leaves and flowers of the plant could serve as a promising alternative to traditional antifungal treatments, potentially offering a safer option with fewer side effects ([1]).
Garlic is another supplement that has been evaluated for its effectiveness against candidiasis. While garlic has shown some antimicrobial properties and may inhibit the growth of Candida fungi, the findings thus far are preliminary. The results indicate that although garlic can be beneficial, more extensive clinical trials are necessary to fully establish its efficacy and safety for treating candidiasis ([2], [3]). Therefore, both Gallesia integrifolia and garlic show potential in the realm of natural treatments for candidiasis, though further research is essential to confirm their roles in clinical practice.
According to user reviews, many have reported significant improvements in their symptoms associated with Candidiasis after using garlic extract. Several users stated that they experienced diminished thrush and have even mentioned a noticeable relief along with an uplifting effect on their overall health. For instance, one user remarked on the complete dissipation of their thrush thanks to the extract, praising its excellent quality and composition (Read Review). Another user highlighted its efficacy in eliminating Candidiasis, adding that their health improved in terms of frequently being sick since starting the supplement (Read Review).
Some reviews suggest that users noticed results relatively quickly—in just a week, one reviewer reported a massive improvement in energy, mood, and digestion after starting the garlic extract, indicating it could effectively address gut microbiome issues alongside Candidiasis (Read Review). While many have experienced positive results, it’s essential to note that individual outcomes can vary greatly, with some users like one who’s been on the product for only a week expressing uncertainty about immediate results but remaining hopeful for the course ahead (Read Review). Overall, anecdotal evidence suggests that garlic extract is a popular choice for those looking to tackle Candidiasis symptoms.
Based on user reviews, many individuals have reported positive experiences when combining garlic extract with other supplements for handling Candidiasis. Users noted that when taken alongside various herbs and supplements during a Candidiasis cleanse, garlic extract appeared effective without an unpleasant taste or strong garlic odor (Read Review). Another reviewer indicated that they took garlic in conjunction with other medications for the prevention of Candida, and they reported satisfactory results (Read Review).
Additionally, some reviews highlight the versatility of garlic extract in combination with other treatments, noting its efficacy in treating related conditions and boosting immunity while managing Candidiasis (Read Review). Users have found that these combinations can enhance overall effectiveness, with one individual taking garlic as part of a complex treatment regimen without any adverse sensations (Read Review). Overall, combining garlic extract with other supplements may provide a synergistic effect for those dealing with Candidiasis.
Based on user reviews, there seems to be a consensus on the effectiveness of garlic extract for treating Candidiasis, with many users highlighting its benefits without needing to consume large quantities of garlic. A frequent dosage appears to be around three capsules twice daily, as noted by a user who reported significant improvement in their condition following this regimen Read Review. Another user mentioned taking it regularly, feeling that it was aiding their recovery Read Review.
Many users appreciate the convenience of capsules as opposed to raw garlic, which can be difficult to digest for some. The garlic extract is praised for being odorless and easy to take, with another user recommending it as an essential part of a Candidiasis cleanse Read Review. Although one user indicated they had not seen results after a week of taking it as prescribed by their doctor, they remained hopeful for a positive outcome after a complete 30-day course Read Review. Overall, users report positive experiences with garlic extract in managing Candidiasis symptoms.
9
Massive improvement
Life saver! I’m taking this for my candidiasis overgrowth and possible gut microbiome issues. I've noticed a massive improvement in energy, mood, and digestion after just a week. No garlic burps or issues; the capsules are small and easy to take. Absolutely delighted!
2
Hopeful for results
1 people found this helpful
I’m using it for candidiasis as prescribed by my doctor. I've been taking it for a week with no results yet, but I remain hopeful. The course lasts 30 days; I'm expecting a positive outcome soon!
9
Effective treatment
An excellent remedy. It acts on fungal films. I have personally used it for Candidiasis treatment. There is a noticeable effect!
9
High-quality extract
1 people found this helpful
Thanks to this extract, my thrush has dissipated. The quality is excellent with a well-selected composition. It’s impossible to consume garlic in such quantities as with this extract. I frequently take this brand and highly recommend it.
9
Sickness reduction
Great product. It helps eliminate Candidiasis, and I’ve noticed I’m rarely sick since I began taking garlic.
7.5
High dosage
I took these along with various other herbs and supplements as part of a Candidiasis cleanse. The dosage is sufficiently high and they seem effective without an aftertaste or strong garlic odour.
7.5
Prevention of candidiasis
1 people found this helpful
I take this for the prevention of candida, combined with other medications, and it works well.
6
Supports immune system
I bought this to strengthen my immunity; it possesses anti-inflammatory and antibacterial properties. It was used alongside other treatments for infectious diseases and effectively helps with thrush.
7.5
No unpleasant sensations
Good, I took it for thrush as part of a complex treatment, while simultaneously addressing worms, and I experienced no unpleasant sensations.
9
Effective against candidiasis
Great! It helped me eliminate chronic tonsillitis and candidiasis without any other medications. I took three capsules twice daily.
7.5
Condition improving
I take it regularly as it has antibacterial action against candidiasis. I definitely feel that my condition is improving. The pills are small and they don’t taste like garlic, making them pleasant to take.
8
G. integrifolia shows antifungal promise
Bioactive compounds with antifungal activity against pathogens isolated from pregnant woman: Gallesia integrifolia (garlic wood) is a promising treatment for vulvovaginal candidiasis.
We investigated the antifungal properties of Gallesia integrifolia, particularly in treating vulvovaginal candidiasis, which affects many pregnant women. This study focused on the plant's leaves and flowers, known for their medicinal uses in folk medicine. By testing different isolates of Candida, the fungi responsible for this infection, we measured the effectiveness of G. integrifolia using a method called broth microdilution.
One of the key findings was that G. integrifolia acted against various Candida species, showing promising results that suggest it could potentially be a natural alternative to traditional antifungal treatments, which sometimes come with negative side effects. We also employed advanced techniques such as gas chromatography to understand the chemical composition of the essential oils in the plant.
Overall, our results indicate that G. integrifolia, particularly its leaves and flowers, could offer a new therapeutic approach for treating vulvovaginal candidiasis, and it brings hope for safer treatments in pregnant women facing this common issue.
8
Garlic's potential in candidiasis treatment
Activity of bioactive garlic compounds on the oral microbiome: a literature review.
We explored the potential of garlic, particularly known for its antimicrobial properties, in treating oral candidiasis—a common fungal infection. The research reviewed evidence on how garlic can effectively combat this condition without the side effects typically associated with conventional treatments.
Garlic derivatives showed promise in managing candidiasis by inhibiting the growth of the Candida fungus. Previous studies highlighted successes in using garlic as an alternative to traditional medications, showing the potential for it to be a natural remedy for those suffering from recurrent oral infections.
However, while the findings suggest garlic's efficacy in treating candidiasis, the studies included are not extensive enough to draw definitive conclusions. More rigorous clinical trials are needed to solidify garlic's role in treating this condition.
Overall, the insights gained from the existing literature point towards garlic as a natural alternative worth further investigation. As demand for natural treatments grows, garlic could become a valuable option in the management of oral health issues.
7
Garlic's mixed effects on candidiasis
Garlic alters the expression of putative virulence factor genes SIR2 and ECE1 in vulvovaginal C. albicans isolates.
We explored the effects of garlic on treating vulvovaginal candidiasis, a condition that can cause significant discomfort for many individuals. Recent observations suggested that garlic could be a beneficial alternative treatment, but the varying successes reported by patients raised questions about its effectiveness.
To investigate further, we examined two clinical strains of Candida albicans from patients who had differing experiences with garlic therapy. Our study focused on two key virulence factor genes: SIR2 and ECE1. Using biofilm assays and real-time PCR, we assessed how these strains responded to both fresh garlic extract and pure allicin, the active component found in crushed garlic.
Our findings revealed that all strains showed a decrease in SIR2 expression after treatment with garlic. However, the response of ECE1 was more complex. In strains from patients who did not respond well to garlic, ECE1 was up-regulated, indicating increased expression. Conversely, in the strain from a patient who benefited from garlic therapy, ECE1 was down-regulated.
These results suggest that while garlic has a consistent effect on certain genes like SIR2, its influence on ECE1 can vary based on individual strain characteristics. Therefore, it is essential for future research to consider these differences when evaluating the effectiveness of phytotherapies like garlic in treating candidiasis.
References
de Souza ANV, Faria MGI, da Rocha CE, Philippsen GS, Silva GCC, et al. Bioactive compounds with antifungal activity against pathogens isolated from pregnant woman: Gallesia integrifolia (garlic wood) is a promising treatment for vulvovaginal candidiasis. J Ethnopharmacol. 2022;295:115403. doi:10.1016/j.jep.2022.115403
Hoglund KB, Barnett BK, Watson SA, Melgarejo MB, Kang Y. Activity of bioactive garlic compounds on the oral microbiome: a literature review. Gen Dent. 2020;68:27.
Said MM, Watson C, Grando D. Garlic alters the expression of putative virulence factor genes SIR2 and ECE1 in vulvovaginal C. albicans isolates. Sci Rep. 2020;10:3615. doi:10.1038/s41598-020-60178-0