Overview

SCIENTIFIC SCORE
Moderately Effective
Based on 14 Researches
8.1
USERS' SCORE
Good
Based on 9 Reviews
8.4
Supplement Facts
Serving Size: 2 Vegetarian Capsules
Amount Per Serving
%DV
Thiamine (vitamin B1) (as thiamine HCl)
100 mg
8333%
Riboflavin (vitamin B2) (as riboflavin and riboflavin 5'-phosphate)
75 mg
5769%
Niacin (as niacinamide and niacin)
100 mg•
625%
Vitamin B6 (as pyridoxine HCl and pyridoxal 5' phosphate)
100 mg
5882%
Folate (as L-5-methyltetrahydrofolate calcium salt)
680 mcg○
170%
Vitamin B12 (as methylcobalamin)
300 mcg
12500%
Biotin
1000 mcg
3333%
Pantothenic acid (as D-calcium pantothenate)
500 mg
10000%
Calcium (as D-calcium pantothenate, dicalcium phosphate)
50 mg
4%
Inositol
100 mg
**
PABA (para-aminobenzoic acid)
50 mg
**

Top Medical Research Studies

9
Vitamin B12 effectively reduces pain
We sought to understand how intramuscular vitamin B12 could help alleviate low back pain in patients with mechanical lumbago. In a rigorous study involving 60 participants, we compared the effects of vitamin B12 to a placebo.

Our findings indicated that those receiving the vitamin reported significantly less pain and disability, as measured by a visual scale and disability questionnaire. Notably, those on vitamin B12 also used less paracetamol than the placebo group.

Overall, our study confirmed that vitamin B12 can be effective for treating low back pain without nutritional deficiency.
Read More
8
Methylcobalamin shows promising effectiveness
This study evaluated the effects of intramuscular methylcobalamin injections on chronic low back pain.

In a rigorously designed double-blinded, randomized controlled trial, 60 patients were divided into treatment and placebo groups.

We observed significant improvements in pain and disability scores among those receiving methylcobalamin compared to the placebo.

Additionally, the treatment was found to be safe, with only minor side effects reported.
Read More
8
Vitamin B complex aids back pain relief
We examined how well celecoxib and a combined vitamin B complex worked for people experiencing lower back pain, comparing them with meloxicam.

Our findings indicated that celecoxib, especially when paired with Neuromultivit (a vitamin B complex), showed improved effectiveness in relieving both acute and chronic back pain.

Interestingly, while meloxicam offered similar initial pain relief, celecoxib was found to be superior for long-term recovery and quality of life improvements.

This suggests that adding vitamin B to treatment could enhance outcomes for those suffering from chronic lower back pain.
Read More

Most Useful Reviews

9
Healed mouth corners
7 people found this helpful
My daughter complained of pain from cracked corners of her mouth. After giving her C and B vitamins, she reported no pain and her healing was swift. This product is a staple in our family for overall health.
Read More
9
Condition alleviated
3 people found this helpful
I loved this complex. With my intervertebral hernia, my constant back pain has decreased after just a week of use. There seems to be a notable improvement in my overall condition and nervous system.
Read More
9
Calmer sleep
The quality of these vitamins is impressive, with a tangible effect and no side effects. They have significantly improved my sleep, making it calmer and much stronger. My nerves are more settled, and I've even managed to nap during the day, which is unusual for me. Additionally, my chronic lower back pain has markedly lessened since starting this complex.
Read More

Medical Researches

SCIENTIFIC SCORE
Moderately Effective
Based on 14 Researches
8.1
  • All Researches
9
Combination therapy shows effectiveness
We set out to explore whether a rehabilitation program combined with specific supplements could effectively treat sciatica in young patients. Our study involved 128 individuals who were divided into three groups: one receiving both rehabilitation and supplements, one only with rehabilitation, and one with only supplements.

After treatment, the group with both rehabilitation and supplements showed significant improvement in pain relief and overall quality of life compared to the others. While the supplement-only group didn’t perform as well, this combination approach proved beneficial, particularly in reducing pain and enhancing stability.
Read More
We explored how effective vitamin B complex, alongside nonsteroidal anti-inflammatory drugs, is in treating back pain. Our study involved 70 patients divided into two groups, one receiving a vitamin B complex blend and the other a different pain relief combination.

Both groups showed improvement, but the first group experienced a clearer reduction in pain levels over time. By the third visit, they reported significantly less discomfort compared to the second group. Though both treatments were effective, the vitamin B complex showed a more pronounced impact on pain relief and patient satisfaction.
Read More
9
Vitamin B12 effectively reduces pain
We sought to understand how intramuscular vitamin B12 could help alleviate low back pain in patients with mechanical lumbago. In a rigorous study involving 60 participants, we compared the effects of vitamin B12 to a placebo.

Our findings indicated that those receiving the vitamin reported significantly less pain and disability, as measured by a visual scale and disability questionnaire. Notably, those on vitamin B12 also used less paracetamol than the placebo group.

Overall, our study confirmed that vitamin B12 can be effective for treating low back pain without nutritional deficiency.
Read More
9
Vitamin B complex effective for pain
We examined how Dolo-Neurobion, a blend of essential B vitamins and an analgesic, affects acute lumbosacral pain. In a study of 53 patients, we found that this treatment yielded good to excellent results in 77.4% of cases, while 15.1% experienced moderate effects. The approach combined initial parenteral dosing with continuation through oral intake, and any necessary antibiotics were also used. Most notably, we observed no significant side effects, making Dolo-Neurobion a promising option for back pain relief linked to pelvic organ issues.
Read More
8
Vitamin B12 aids postoperative recovery
We explored how combining dexamethasone with vitamin B12 could impact early recovery from back and leg pain after a specific spine surgery called percutaneous endoscopic interlaminar discectomy (PEID).

In our study, patients were divided into two groups: one received only the surgery, while the other got epidural injections of both medications during surgery.

Results showed that the combined treatment significantly reduced pain and inflammation, leading to better early recovery outcomes. This suggests that using this combination might be a great option for patients undergoing this type of surgery.
Read More

User Reviews

USERS' SCORE
Good
Based on 9 Reviews
8.4
  • All Reviews
  • Positive Reviews
  • Negative Reviews
9
Healed mouth corners
7 people found this helpful
My daughter complained of pain from cracked corners of her mouth. After giving her C and B vitamins, she reported no pain and her healing was swift. This product is a staple in our family for overall health.
Read More
9
Condition alleviated
3 people found this helpful
I loved this complex. With my intervertebral hernia, my constant back pain has decreased after just a week of use. There seems to be a notable improvement in my overall condition and nervous system.
Read More
9
Calmer sleep
The quality of these vitamins is impressive, with a tangible effect and no side effects. They have significantly improved my sleep, making it calmer and much stronger. My nerves are more settled, and I've even managed to nap during the day, which is unusual for me. Additionally, my chronic lower back pain has markedly lessened since starting this complex.
Read More
9
Great improvement felt
I took the product after stopping another one. Unfortunately, the symptoms returned, so I reverted to my previous product and felt a significant improvement.
Read More
7.5
Back pain relief
It definitely works! This product relieves pain in my back (nerve endings), and combined with magnesium, it calms me like an elephant.
Read More

Frequently Asked Questions

9
Condition alleviated
3 people found this helpful
I loved this complex. With my intervertebral hernia, my constant back pain has decreased after just a week of use. There seems to be a notable improvement in my overall condition and nervous system.
9
Calmer sleep
The quality of these vitamins is impressive, with a tangible effect and no side effects. They have significantly improved my sleep, making it calmer and much stronger. My nerves are more settled, and I've even managed to nap during the day, which is unusual for me. Additionally, my chronic lower back pain has markedly lessened since starting this complex.
7.5
Reduced head and back pain
1 people found this helpful
I take it annually and find it well tolerated. I notice its effects immediately after taking it; both my head and back hurt less.
9
Great improvement felt
I took the product after stopping another one. Unfortunately, the symptoms returned, so I reverted to my previous product and felt a significant improvement.
9
Healed mouth corners
7 people found this helpful
My daughter complained of pain from cracked corners of her mouth. After giving her C and B vitamins, she reported no pain and her healing was swift. This product is a staple in our family for overall health.
7.5
Back pain relief
It definitely works! This product relieves pain in my back (nerve endings), and combined with magnesium, it calms me like an elephant.
9
Excellent support
1 people found this helpful
After considering many options, I chose this B complex. It supports my nervous system and enhances absorption of magnesium, calcium, and other trace elements. It's an excellent remedy for neuralgia and various back problems. I highly recommend it.
6
More energy
While it has flaws, this B-complex is better than many alternatives. The manufacturers seem to prefer higher dosages for profit, meaning I often divided one capsule into multiple doses. Although niacin can cause temporary flushing, it’s normal. After trying several brands, I find this B-complex to outperform others. My muscle pains have reduced, I feel more energetic, and my sleep quality has improved. Ideally, I recommend taking B vitamins separately, but this complex is a suitable option for beginners in supplementation.
We analyzed a study that looked at how B vitamins—B1, B6, and B12—work alongside diclofenac to help relieve back pain in people suffering from acute lumbago.

In a randomized, double-blind trial, participants received either diclofenac plus B vitamins or diclofenac alone. After three days, those taking the combination therapy reported significantly better pain relief and mobility than those on diclofenac only.

Despite the encouraging results, we noted that the study recorded pain measurements only until participants withdrew, which could impact the findings.
8
Vitamin B complex aids back pain relief
We examined how well celecoxib and a combined vitamin B complex worked for people experiencing lower back pain, comparing them with meloxicam.

Our findings indicated that celecoxib, especially when paired with Neuromultivit (a vitamin B complex), showed improved effectiveness in relieving both acute and chronic back pain.

Interestingly, while meloxicam offered similar initial pain relief, celecoxib was found to be superior for long-term recovery and quality of life improvements.

This suggests that adding vitamin B to treatment could enhance outcomes for those suffering from chronic lower back pain.
9
Vitamin B12 effectively reduces pain
We sought to understand how intramuscular vitamin B12 could help alleviate low back pain in patients with mechanical lumbago. In a rigorous study involving 60 participants, we compared the effects of vitamin B12 to a placebo.

Our findings indicated that those receiving the vitamin reported significantly less pain and disability, as measured by a visual scale and disability questionnaire. Notably, those on vitamin B12 also used less paracetamol than the placebo group.

Overall, our study confirmed that vitamin B12 can be effective for treating low back pain without nutritional deficiency.
9
Combination therapy shows effectiveness
We set out to explore whether a rehabilitation program combined with specific supplements could effectively treat sciatica in young patients. Our study involved 128 individuals who were divided into three groups: one receiving both rehabilitation and supplements, one only with rehabilitation, and one with only supplements.

After treatment, the group with both rehabilitation and supplements showed significant improvement in pain relief and overall quality of life compared to the others. While the supplement-only group didn’t perform as well, this combination approach proved beneficial, particularly in reducing pain and enhancing stability.

References

  1. He C, Li J, Hu W, Xiao B, Fan T, et al. Effects of dexamethasone combined with vitamin B12 on percutaneous endoscopic interlaminar discectomy early outcomes: a randomized controlled trial. J Orthop Surg Res. 2024;19:733. 10.1186/s13018-024-05210-z
  2. Scaturro D, Vitagliani F, Tomasello S, Sconza C, Respizzi S, et al. Combined Rehabilitation with Alpha Lipoic Acid, Acetyl-L-Carnitine, Resveratrol, and Cholecalciferolin Discogenic Sciatica in Young People: A Randomized Clinical Trial. Medicina (Kaunas). 2023;59. 10.3390/medicina59122197
  3. Antonen EG, Kruchek MM, Nikitina MV. [Evaluation of the effectiveness of treatment of patients with nonspecific pain syndrome in the lower back with celecoxib and a combined preparation of B vitamins]. Zh Nevrol Psikhiatr Im S S Korsakova. 2022;122:65. 10.17116/jnevro202212208165
  4. Barantsevich ER, Yakovlev AA, Gavrilova EA, Gavrichenko AV, Pushkarev MS, et al. [Study of the clinical efficacy and safety of the scheme of step therapy of nonsteroidal anti-inflammatory drugs and a complex of B vitamins in patients with low back pain]. Zh Nevrol Psikhiatr Im S S Korsakova. 2021;121:67. 10.17116/jnevro202112110167
  5. Nava-Mesa MO, Aispuru Lanche GR. [Role of B vitamins, thiamine, pyridoxine, and cyanocobalamin in back pain and other musculoskeletal conditions: a narrative review]. Semergen. 2021;47:551. 10.1016/j.semerg.2021.01.010
  6. Calderon-Ospina CA, Nava-Mesa MO, Arbeláez Ariza CE. Effect of Combined Diclofenac and B Vitamins (Thiamine, Pyridoxine, and Cyanocobalamin) for Low Back Pain Management: Systematic Review and Meta-analysis. Pain Med. 2020;21:766. 10.1093/pm/pnz216
  7. Khabirov FA, Khaibullin TI, Granatov EV. [Evaluation of efficiency and safety of adding neuromultivit to basic therapy of vertebrogenic radiculopathy]. Zh Nevrol Psikhiatr Im S S Korsakova. 2017;117:38. 10.17116/jnevro201711710138-43
  8. Chiu CK, Low TH, Tey YS, Singh VA, Shong HK. The efficacy and safety of intramuscular injections of methylcobalamin in patients with chronic nonspecific low back pain: a randomised controlled trial. Singapore Med J. 2011;52:868.
  9. Levin OS, Moseĭkin IA. [Vitamin B complex (milgamma) in the treatment of vertebrogenic lumbosacral radiculopathy]. Zh Nevrol Psikhiatr Im S S Korsakova. 2009;109:30.
  10. Mibielli MA, Geller M, Cohen JC, Goldberg SG, Cohen MT, et al. Diclofenac plus B vitamins versus diclofenac monotherapy in lumbago: the DOLOR study. Curr Med Res Opin. 2009;25:2589. 10.3111/13696990903246911
  11. Mauro GL, Martorana U, Cataldo P, Brancato G, Letizia G. Vitamin B12 in low back pain: a randomised, double-blind, placebo-controlled study. Eur Rev Med Pharmacol Sci. 2000;4:53.
  12. Brüggemann G, Koehler CO, Koch EM. [Results of a double-blind study of diclofenac + vitamin B1, B6, B12 versus diclofenac in patients with acute pain of the lumbar vertebrae. A multicenter study]. Klin Wochenschr. 1990;68:116.
  13. Kuhlwein A, Meyer HJ, Koehler CO. [Reduced diclofenac administration by B vitamins: results of a randomized double-blind study with reduced daily doses of diclofenac (75 mg diclofenac versus 75 mg diclofenac plus B vitamins) in acute lumbar vertebral syndromes]. Klin Wochenschr. 1990;68:107.
  14. Kunt T. [Complaints in the lumbosacral region and their management with Dolo-Neurobion]. Fortschr Med. 1978;96:299.
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