SCIENTIFIC SCORE
Possibly Effective
Based on 2 Researches
7.5
USERS' SCORE
Good
Based on 22 Reviews
8.6
Supplement Facts
Serving Size: 2 Vegetarian Capsules
Amount Per Serving
%DV
Thiamine (vitamin B1) (as thiamine HCl)
100 mg
8333%
Riboflavin (vitamin B2) (as riboflavin and riboflavin 5'-phosphate)
75 mg
5769%
Niacin (as niacinamide and niacin)
100 mg•
625%
Vitamin B6 (as pyridoxine HCl and pyridoxal 5' phosphate)
100 mg
5882%
Folate (as L-5-methyltetrahydrofolate calcium salt)
680 mcg○
170%
Vitamin B12 (as methylcobalamin)
300 mcg
12500%
Biotin
1000 mcg
3333%
Pantothenic acid (as D-calcium pantothenate)
500 mg
10000%
Calcium (as D-calcium pantothenate, dicalcium phosphate)
50 mg
4%
Inositol
100 mg
**
PABA (para-aminobenzoic acid)
50 mg
**

Top Medical Research Studies

8
Pyridoxine promotes glioblastoma cell death
Effect of pyridoxine or cobalamin supplementation on apoptosis and cell cycle progression in a human glioblastoma cell line.
Relevant vitamin therapy insights
We explored the effect of vitamin B6 (pyridoxine) and B12 (cobalamin) on human glioblastoma cells, known for their aggressive nature. By treating cell cultures with varying doses of these vitamins over 24-72 hours, we aimed to see how they influenced cell survival and progression through their life cycle.

Our findings revealed that pyridoxine significantly reduced cell viability, likely due to inducing apoptosis, while cobalamin demonstrated some protective qualities against this effect. Although cobalamin did not boost apoptosis directly, it did intervene in the negative impact of pyridoxine on cell viability.
Read More
7
Nicotinamide induces reversible senescence
Nicotinamide metabolism reprogramming drives reversible senescence of glioblastoma cells.
Moderate relevance to brain tumor research
We investigated how nicotinamide, a form of vitamin B3, impacts glioblastoma (GB) cells. Our findings reveal that it can induce a state of senescence, slowing down cell growth and altering their internal processes.

While these senescent cells showed reduced tumor-forming capabilities, they maintained some level of tumor potential and proved to be reversible. This suggests nicotinamide could offer insights into managing GB, though its effects may vary and further research is essential.
Read More

Most Useful Reviews

9.5
Relief and improvement
I follow the keto diet and have a fibroid tumour in my uterus. The doctor prescribed this product, and I found it to be wonderful. I experienced significant relief, and my health and mental state improved. The tumour is small, and I highly recommend it. The quality is excellent, the ingredients are good, and the quantity is sufficient. There is no noticeable taste, and the packaging is nice.
Read More
9.5
Immediate boost for parents
Excellent energy booster! I purchased these vitamins for my parents, aged 59 and 60, as they often felt exhausted upon waking. Their doctor advised a B-complex for brain and heart health. After starting the supplement, they quickly felt revitalised and energetic. They've become more active and now enjoy their time outdoors.
Read More
9.5
Vitality boost experienced
I will definitely repurchase these vitamins! They support my body tremendously. Everyone knows B vitamins are vital for healthy function; they improve my immune, circulatory, and nervous systems while enhancing brain function and metabolism. After a full course, I experienced an incredible boost in vitality, and I no longer struggled with sleep issues or stress. Additionally, my skin has improved due to these vitamins, as my acne cleared noticeably. Importantly, there were no side effects, apart from the usual bright yellow urine. I was pleasantly surprised by their effectiveness and will buy more come springtime.
Read More

Medical Researches

SCIENTIFIC SCORE
Possibly Effective
Based on 2 Researches
7.5
  • All Researches
8
Pyridoxine promotes glioblastoma cell death
Effect of pyridoxine or cobalamin supplementation on apoptosis and cell cycle progression in a human glioblastoma cell line.
Relevant vitamin therapy insights
We explored the effect of vitamin B6 (pyridoxine) and B12 (cobalamin) on human glioblastoma cells, known for their aggressive nature. By treating cell cultures with varying doses of these vitamins over 24-72 hours, we aimed to see how they influenced cell survival and progression through their life cycle.

Our findings revealed that pyridoxine significantly reduced cell viability, likely due to inducing apoptosis, while cobalamin demonstrated some protective qualities against this effect. Although cobalamin did not boost apoptosis directly, it did intervene in the negative impact of pyridoxine on cell viability.
Read More
7
Nicotinamide induces reversible senescence
Nicotinamide metabolism reprogramming drives reversible senescence of glioblastoma cells.
Moderate relevance to brain tumor research
We investigated how nicotinamide, a form of vitamin B3, impacts glioblastoma (GB) cells. Our findings reveal that it can induce a state of senescence, slowing down cell growth and altering their internal processes.

While these senescent cells showed reduced tumor-forming capabilities, they maintained some level of tumor potential and proved to be reversible. This suggests nicotinamide could offer insights into managing GB, though its effects may vary and further research is essential.
Read More

User Reviews

USERS' SCORE
Good
Based on 22 Reviews
8.6
  • All Reviews
  • Positive Reviews
  • Negative Reviews
9.5
Relief and improvement
I follow the keto diet and have a fibroid tumour in my uterus. The doctor prescribed this product, and I found it to be wonderful. I experienced significant relief, and my health and mental state improved. The tumour is small, and I highly recommend it. The quality is excellent, the ingredients are good, and the quantity is sufficient. There is no noticeable taste, and the packaging is nice.
Read More
9.5
Immediate boost for parents
Excellent energy booster! I purchased these vitamins for my parents, aged 59 and 60, as they often felt exhausted upon waking. Their doctor advised a B-complex for brain and heart health. After starting the supplement, they quickly felt revitalised and energetic. They've become more active and now enjoy their time outdoors.
Read More
9.5
Vitality boost experienced
I will definitely repurchase these vitamins! They support my body tremendously. Everyone knows B vitamins are vital for healthy function; they improve my immune, circulatory, and nervous systems while enhancing brain function and metabolism. After a full course, I experienced an incredible boost in vitality, and I no longer struggled with sleep issues or stress. Additionally, my skin has improved due to these vitamins, as my acne cleared noticeably. Importantly, there were no side effects, apart from the usual bright yellow urine. I was pleasantly surprised by their effectiveness and will buy more come springtime.
Read More
9.5
Cognitive enhancement
This B complex is one of the best available. I take it after a meal and have experienced significant improvements in nerve and cardiovascular function, skin condition, and energy metabolism. Vitamin B1 is crucial for brain function, optimising cognitive activity and protecting neurons, especially important for vulnerable groups such as children and the elderly.
Read More
9
Skin health improved
These B vitamins are fantastic! I took two tablets daily after meals, and the results speak for themselves. My skin appears revitalised without creams, and my energy levels surged. My cognitive function improved, evident from my husband's observations. I’m ordering more as these have dramatically enhanced my health.
Read More

Frequently Asked Questions

No FAQs are available for this product and symptom.
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