SCIENTIFIC SCORE
Moderately Effective
Based on 5 Researches
8
USERS' SCORE
Good
Based on 16 Reviews
8.6
Supplement Facts
Serving Size: 2 Vegetarian Capsules
Amount Per Serving
%DV
Thiamine (vitamin B1) (as thiamine HCl)
100 mg
8333%
Riboflavin (vitamin B2) (as riboflavin and riboflavin 5'-phosphate)
75 mg
5769%
Niacin (as niacinamide and niacin)
100 mg•
625%
Vitamin B6 (as pyridoxine HCl and pyridoxal 5' phosphate)
100 mg
5882%
Folate (as L-5-methyltetrahydrofolate calcium salt)
680 mcg○
170%
Vitamin B12 (as methylcobalamin)
300 mcg
12500%
Biotin
1000 mcg
3333%
Pantothenic acid (as D-calcium pantothenate)
500 mg
10000%
Calcium (as D-calcium pantothenate, dicalcium phosphate)
50 mg
4%
Inositol
100 mg
**
PABA (para-aminobenzoic acid)
50 mg
**

Top Medical Research Studies

9
Vitamin B6 aids heart recovery
Vitamin B6 allosterically activates AMPK to promote postischemic angiogenesis in mice.
High relevance for cardiovascular health
We investigated how vitamin B6 supports heart recovery after heart attacks by promoting new blood vessel growth, known as angiogenesis. In laboratory tests, vitamin B6 improved cell migration and tubule formation, vital for forming new blood vessels.

Remarkably, long-term vitamin B6 supplementation showed significant improvements in heart function and reduced inflammation in mice following heart attacks. This suggests that vitamin B6 could be a beneficial aid for heart recovery, harnessing a specific pathway involving a protein called AMPK.
Read More
8
Folate slows artery thickness increase
Serum folate levels, but not vitamin B12, are associated with slower progression in carotid intima-media thickness in a population exposed to mandatory folic acid fortification.
Relevant findings on folate's impact.
We examined the link between folate and vitamin B12 levels and changes in carotid intima-media thickness (cIMT), a marker of early heart disease, over eight years in a group of 5061 adults in Brazil.

Our results suggest that higher serum folate levels are associated with a slower increase in cIMT, indicating a potential protective effect against heart disease.

However, no such benefit was observed with vitamin B12 levels. This implies that while folate may play a role in cardiovascular health, vitamin B12 might not have the same impact.
Read More
8
Gene-nutrient interactions and hypertension
Genome-Wide Approach of Gene-Nutrient Intake Interaction Study for Essential Hypertension in a Large Korean Cohort (KoGES).
High relevance to hypertension research
We explored how specific gene-nutrient interactions affect high blood pressure using data from the Korean Genome and Epidemiology Study, which included over 50,000 participants.

Our findings revealed that individuals with a certain genetic variant showed a lower risk of hypertension when consuming higher amounts of dietary iron and vitamin B6.

This suggests that for some individuals, adjusting their diet could help mitigate hypertension risks.

However, further research is needed to confirm these results across different populations to ensure wider applicability.
Read More

Most Useful Reviews

9.5
Calmed emotional state
B vitamins enhance cerebral circulation, normalise cardiovascular functions, and support the immune system. After taking it consistently, I feel calmer and less reactive to stimuli. Symptoms like dizziness and palpitations have disappeared, and my digestion has improved. I will continue to take this beneficial complex.
Read More
9.5
Cognitive functions improved
This B-complex was recommended by my neurologist, and as someone who has experienced multiple concussions in my younger years, I value their advice. As I'm in my early 50s, I realised the essential role B vitamins play in cognitive functions. After thorough research on its composition, I began taking it and found that my stress levels decreased, sleep improved, and memory was enhanced. I plan to continue taking this effective B-complex twice a year and hope others find my review helpful.
Read More
8.8
Boosts energy levels
B complex vitamins support energy conversion, enhancing overall tone. They are crucial for the health of the nervous system, helping to reduce fatigue, stress, and anxiety. Additionally, they are involved in metabolic processes, improving the absorption of proteins, fats, and carbohydrates, and contribute to the health of skin, hair, and nails. Vitamins B6, B9, and B12 help maintain normal homocysteine levels, essential for cardiovascular health.
Read More

Medical Researches

SCIENTIFIC SCORE
Moderately Effective
Based on 5 Researches
8
  • All Researches
9
Vitamin B6 aids heart recovery
Vitamin B6 allosterically activates AMPK to promote postischemic angiogenesis in mice.
High relevance for cardiovascular health
We investigated how vitamin B6 supports heart recovery after heart attacks by promoting new blood vessel growth, known as angiogenesis. In laboratory tests, vitamin B6 improved cell migration and tubule formation, vital for forming new blood vessels.

Remarkably, long-term vitamin B6 supplementation showed significant improvements in heart function and reduced inflammation in mice following heart attacks. This suggests that vitamin B6 could be a beneficial aid for heart recovery, harnessing a specific pathway involving a protein called AMPK.
Read More
8
Gene-nutrient interactions and hypertension
Genome-Wide Approach of Gene-Nutrient Intake Interaction Study for Essential Hypertension in a Large Korean Cohort (KoGES).
High relevance to hypertension research
We explored how specific gene-nutrient interactions affect high blood pressure using data from the Korean Genome and Epidemiology Study, which included over 50,000 participants.

Our findings revealed that individuals with a certain genetic variant showed a lower risk of hypertension when consuming higher amounts of dietary iron and vitamin B6.

This suggests that for some individuals, adjusting their diet could help mitigate hypertension risks.

However, further research is needed to confirm these results across different populations to ensure wider applicability.
Read More
8
Folate slows artery thickness increase
Serum folate levels, but not vitamin B12, are associated with slower progression in carotid intima-media thickness in a population exposed to mandatory folic acid fortification.
Relevant findings on folate's impact.
We examined the link between folate and vitamin B12 levels and changes in carotid intima-media thickness (cIMT), a marker of early heart disease, over eight years in a group of 5061 adults in Brazil.

Our results suggest that higher serum folate levels are associated with a slower increase in cIMT, indicating a potential protective effect against heart disease.

However, no such benefit was observed with vitamin B12 levels. This implies that while folate may play a role in cardiovascular health, vitamin B12 might not have the same impact.
Read More
8
Niacin intake lowers mortality risks
Association of dietary niacin intake with all-cause and cardiovascular mortality: National Health and Nutrition Examination Survey (NHANES) 2003-2018.
Significant association in findings
We looked into how dietary niacin might affect mortality rates, particularly for cardiovascular disease. Analyzing data from nearly 27,000 U.S. adults over about nine years, we found that those with the highest niacin intake had a significantly lower risk of dying from any cause, as well as from heart-related issues.

Interestingly, this protective effect was more robust among those without diabetes, suggesting that niacin's benefits can vary by health condition. Our findings highlight the potential role of diet in supporting heart health.
Read More
7
Vitamin B influence on hypertension
Relationship between blood pressure variability and vitamin B level in essential hypertension.
Moderate relevance to hypertension study.
We investigated the connection between blood pressure variability (BPV) and vitamin B6 and B12 levels in individuals with essential hypertension. Our study involved 100 patients with hypertension and a control group of 100 healthy individuals.

We found that patients with hypertension had significantly lower levels of these B vitamins compared to the healthy group. Additionally, those with higher B vitamin levels exhibited reduced BPV.

This suggests that Vitamin B6 and B12 may influence blood pressure control, providing insights into hypertension management strategies.
Read More

User Reviews

USERS' SCORE
Good
Based on 16 Reviews
8.6
  • All Reviews
  • Positive Reviews
  • Negative Reviews
9.5
Calmed emotional state
B vitamins enhance cerebral circulation, normalise cardiovascular functions, and support the immune system. After taking it consistently, I feel calmer and less reactive to stimuli. Symptoms like dizziness and palpitations have disappeared, and my digestion has improved. I will continue to take this beneficial complex.
Read More
9.5
Cognitive functions improved
This B-complex was recommended by my neurologist, and as someone who has experienced multiple concussions in my younger years, I value their advice. As I'm in my early 50s, I realised the essential role B vitamins play in cognitive functions. After thorough research on its composition, I began taking it and found that my stress levels decreased, sleep improved, and memory was enhanced. I plan to continue taking this effective B-complex twice a year and hope others find my review helpful.
Read More
8.8
Boosts energy levels
B complex vitamins support energy conversion, enhancing overall tone. They are crucial for the health of the nervous system, helping to reduce fatigue, stress, and anxiety. Additionally, they are involved in metabolic processes, improving the absorption of proteins, fats, and carbohydrates, and contribute to the health of skin, hair, and nails. Vitamins B6, B9, and B12 help maintain normal homocysteine levels, essential for cardiovascular health.
Read More
9.5
Improves sleep quality
B vitamins positively impact our body; their deficiency can lead to cardiovascular disease. They benefit the nervous system by enhancing sleep, reducing anxiety, and combatting stress. It's advisable to take these vitamins as a complex, as they improve each other's effects. We take them as a family and are very satisfied. Remember to take them with water to avoid adverse reactions. I highly recommend them.
Read More
8.5
Improved health overall
A great option for a complex of B vitamins for the whole family. I started taking it immediately after receiving the parcel, and the results have been positive. We have been taking one tablet a day for two weeks, and my general health has improved, particularly regarding digestion and the cardiovascular system.
Read More

Frequently Asked Questions

No FAQs are available for this product and symptom.
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