We investigated how vitamin B6 supports heart recovery after heart attacks by promoting new blood vessel growth, known as angiogenesis. In laboratory tests, vitamin B6 improved cell migration and tubule formation, vital for forming new blood vessels.
Remarkably, long-term vitamin B6 supplementation showed significant improvements in heart function and reduced inflammation in mice following heart attacks. This suggests that vitamin B6 could be a beneficial aid for heart recovery, harnessing a specific pathway involving a protein called AMPK.
Read More
8
Folate slows artery thickness increase
Serum folate levels, but not vitamin B12, are associated with slower progression in carotid intima-media thickness in a population exposed to mandatory folic acid fortification.
We examined the link between folate and vitamin B12 levels and changes in carotid intima-media thickness (cIMT), a marker of early heart disease, over eight years in a group of 5061 adults in Brazil.
Our results suggest that higher serum folate levels are associated with a slower increase in cIMT, indicating a potential protective effect against heart disease.
However, no such benefit was observed with vitamin B12 levels. This implies that while folate may play a role in cardiovascular health, vitamin B12 might not have the same impact.
Read More
8
Gene-nutrient interactions and hypertension
Genome-Wide Approach of Gene-Nutrient Intake Interaction Study for Essential Hypertension in a Large Korean Cohort (KoGES).
We explored how specific gene-nutrient interactions affect high blood pressure using data from the Korean Genome and Epidemiology Study, which included over 50,000 participants.
Our findings revealed that individuals with a certain genetic variant showed a lower risk of hypertension when consuming higher amounts of dietary iron and vitamin B6.
This suggests that for some individuals, adjusting their diet could help mitigate hypertension risks.
However, further research is needed to confirm these results across different populations to ensure wider applicability.
Read More
Most Useful Reviews
9
Calmed emotional state
7 people found this helpful
B vitamins enhance cerebral circulation, normalise cardiovascular functions, and support the immune system. After taking it consistently, I feel calmer and less reactive to stimuli. Symptoms like dizziness and palpitations have disappeared, and my digestion has improved. I will continue to take this beneficial complex.
Read More
9
Cognitive functions improved
6 people found this helpful
This B-complex was recommended by my neurologist, and as someone who has experienced multiple concussions in my younger years, I value their advice. As I'm in my early 50s, I realised the essential role B vitamins play in cognitive functions. After thorough research on its composition, I began taking it and found that my stress levels decreased, sleep improved, and memory was enhanced. I plan to continue taking this effective B-complex twice a year and hope others find my review helpful.
Read More
7.5
Boosts energy levels
5 people found this helpful
B complex vitamins support energy conversion, enhancing overall tone. They are crucial for the health of the nervous system, helping to reduce fatigue, stress, and anxiety. Additionally, they are involved in metabolic processes, improving the absorption of proteins, fats, and carbohydrates, and contribute to the health of skin, hair, and nails. Vitamins B6, B9, and B12 help maintain normal homocysteine levels, essential for cardiovascular health.
We investigated how vitamin B6 supports heart recovery after heart attacks by promoting new blood vessel growth, known as angiogenesis. In laboratory tests, vitamin B6 improved cell migration and tubule formation, vital for forming new blood vessels.
Remarkably, long-term vitamin B6 supplementation showed significant improvements in heart function and reduced inflammation in mice following heart attacks. This suggests that vitamin B6 could be a beneficial aid for heart recovery, harnessing a specific pathway involving a protein called AMPK.
Read More
8
Gene-nutrient interactions and hypertension
Genome-Wide Approach of Gene-Nutrient Intake Interaction Study for Essential Hypertension in a Large Korean Cohort (KoGES).
We explored how specific gene-nutrient interactions affect high blood pressure using data from the Korean Genome and Epidemiology Study, which included over 50,000 participants.
Our findings revealed that individuals with a certain genetic variant showed a lower risk of hypertension when consuming higher amounts of dietary iron and vitamin B6.
This suggests that for some individuals, adjusting their diet could help mitigate hypertension risks.
However, further research is needed to confirm these results across different populations to ensure wider applicability.
Read More
8
Folate slows artery thickness increase
Serum folate levels, but not vitamin B12, are associated with slower progression in carotid intima-media thickness in a population exposed to mandatory folic acid fortification.
We examined the link between folate and vitamin B12 levels and changes in carotid intima-media thickness (cIMT), a marker of early heart disease, over eight years in a group of 5061 adults in Brazil.
Our results suggest that higher serum folate levels are associated with a slower increase in cIMT, indicating a potential protective effect against heart disease.
However, no such benefit was observed with vitamin B12 levels. This implies that while folate may play a role in cardiovascular health, vitamin B12 might not have the same impact.
Read More
8
Niacin intake lowers mortality risks
Association of dietary niacin intake with all-cause and cardiovascular mortality: National Health and Nutrition Examination Survey (NHANES) 2003-2018.
We looked into how dietary niacin might affect mortality rates, particularly for cardiovascular disease. Analyzing data from nearly 27,000 U.S. adults over about nine years, we found that those with the highest niacin intake had a significantly lower risk of dying from any cause, as well as from heart-related issues.
Interestingly, this protective effect was more robust among those without diabetes, suggesting that niacin's benefits can vary by health condition. Our findings highlight the potential role of diet in supporting heart health.
Read More
7
Vitamin B influence on hypertension
Relationship between blood pressure variability and vitamin B level in essential hypertension.
We investigated the connection between blood pressure variability (BPV) and vitamin B6 and B12 levels in individuals with essential hypertension. Our study involved 100 patients with hypertension and a control group of 100 healthy individuals.
We found that patients with hypertension had significantly lower levels of these B vitamins compared to the healthy group. Additionally, those with higher B vitamin levels exhibited reduced BPV.
This suggests that Vitamin B6 and B12 may influence blood pressure control, providing insights into hypertension management strategies.
Read More
User Reviews
USERS' SCORE
Moderately Good
Based on 16 Reviews
7.7
All Reviews
Positive Reviews
Negative Reviews
9
Calmed emotional state
7 people found this helpful
B vitamins enhance cerebral circulation, normalise cardiovascular functions, and support the immune system. After taking it consistently, I feel calmer and less reactive to stimuli. Symptoms like dizziness and palpitations have disappeared, and my digestion has improved. I will continue to take this beneficial complex.
Read More
9
Cognitive functions improved
6 people found this helpful
This B-complex was recommended by my neurologist, and as someone who has experienced multiple concussions in my younger years, I value their advice. As I'm in my early 50s, I realised the essential role B vitamins play in cognitive functions. After thorough research on its composition, I began taking it and found that my stress levels decreased, sleep improved, and memory was enhanced. I plan to continue taking this effective B-complex twice a year and hope others find my review helpful.
Read More
7.5
Boosts energy levels
5 people found this helpful
B complex vitamins support energy conversion, enhancing overall tone. They are crucial for the health of the nervous system, helping to reduce fatigue, stress, and anxiety. Additionally, they are involved in metabolic processes, improving the absorption of proteins, fats, and carbohydrates, and contribute to the health of skin, hair, and nails. Vitamins B6, B9, and B12 help maintain normal homocysteine levels, essential for cardiovascular health.
Read More
9
Improves sleep quality
B vitamins positively impact our body; their deficiency can lead to cardiovascular disease. They benefit the nervous system by enhancing sleep, reducing anxiety, and combatting stress. It's advisable to take these vitamins as a complex, as they improve each other's effects. We take them as a family and are very satisfied. Remember to take them with water to avoid adverse reactions. I highly recommend them.
Read More
7
Improved health overall
269 people found this helpful
A great option for a complex of B vitamins for the whole family. I started taking it immediately after receiving the parcel, and the results have been positive. We have been taking one tablet a day for two weeks, and my general health has improved, particularly regarding digestion and the cardiovascular system.
Cardiovascular disease (CVD) is a broad term that encompasses a range of heart and blood vessel disorders. This can include conditions such as coronary artery disease, which leads to heart attacks; cerebrovascular disease that results in strokes; and peripheral artery disease affecting blood flow to the limbs. The key risk factors for CVD often include high blood pressure, high cholesterol, obesity, smoking, a sedentary lifestyle, and diabetes. By identifying and managing these risk factors, individuals can significantly reduce their likelihood of developing cardiovascular problems.
Prevention and treatment strategies often involve lifestyle modifications such as adopting a heart-healthy diet rich in fruits, vegetables, whole grains, and lean proteins, alongside engaging in regular physical activity. In some cases, medications might be necessary to control blood pressure or cholesterol levels. Regular check-ups with a healthcare provider are essential for monitoring heart health, especially for individuals with a family history of CVD. Understanding the signs and symptoms of cardiovascular issues—like chest pain, shortness of breath, or fatigue—can help in seeking timely medical attention, ultimately leading to better outcomes.
Vitamin B Complex refers to a group of water-soluble vitamins that play important roles in cell metabolism and overall health. This group typically includes eight essential vitamins: B1 (thiamine), B2 (riboflavin), B3 (niacin), B5 (pantothenic acid), B6 (pyridoxine), B7 (biotin), B9 (folate), and B12 (cobalamin). Each of these vitamins contributes uniquely to various bodily functions, such as energy production, red blood cell formation, and nervous system function. For instance, B12 and folate are crucial in preventing anemia, while B6 is vital for brain development and function.
Many people can obtain their daily requirements of B vitamins through a balanced diet that includes whole grains, meats, eggs, nuts, leafy greens, and dairy products. However, certain groups—like vegetarians, pregnant women, and older adults—may benefit from supplementation to meet their nutritional needs. It's important to consult with a healthcare professional before starting any supplement regimen, as excessive intake of certain B vitamins can lead to adverse effects. Overall, ensuring adequate intake of Vitamin B Complex is vital for maintaining energy levels and supporting overall health.
Based on user reviews, the timeline for seeing results from taking a B-complex vitamin for cardiovascular support varies. Many users report experiencing noticeable benefits within two weeks of consistent use. For instance, one reviewer mentioned that after two weeks of taking the supplement, their energy levels increased significantly and they felt an overall improvement in well-being, particularly related to digestion and cardiovascular health Read Review. Similarly, another user indicated that they felt less nervous and more balanced after just a few days Read Review.
However, other users noted that more profound effects, such as long-term benefits regarding stress management and cardiovascular function, took a couple of months or longer to fully manifest. One individual, who has been using the complex for two years, reported feeling calmer and experiencing comprehensive health improvements over time Read Review. Generally, users seem to agree that consistency is key, and while some quick improvements can be felt, the most significant benefits develop with continued use.
There is emerging scientific support for the role of certain B vitamins in cardiovascular health, particularly vitamin B6 and folate. A study demonstrated that higher levels of vitamin B6 not only supported heart recovery post-heart attack by promoting new blood vessel growth but also improved heart function and reduced inflammation in laboratory settings [2]. In another investigation, high serum folate levels were associated with a slower increase in carotid intima-media thickness, a marker of early heart disease, suggesting that folate might offer protective benefits against cardiovascular issues [4].
Additionally, findings from a broader study reveal a correlation between dietary niacin intake and reduced mortality rates related to cardiovascular disease, emphasizing that nutrition plays a crucial role in heart health [5]. However, while these results are promising, further research is necessary to establish more definitive conclusions and identify the most effective dietary strategies for heart health. Overall, while not uniformly conclusive, the evidence points to a potential cardiovascular benefit from maintaining adequate B vitamin levels.
Users have reported a variety of positive improvements in symptoms after incorporating a B-complex vitamin into their daily routine. Many individuals noted a significant enhancement in emotional well-being, with reductions in anxiety and stress levels. For instance, one user mentioned feeling calmer and less reactive to stimuli, and reported that symptoms such as dizziness and palpitations had disappeared Read Review. Another user, who experienced multiple concussions, observed improved sleep and memory function, attributing these benefits to regular B-complex intake Read Review.
Physical health improvements were also widely reported, with users noting enhanced digestion and overall cardiovascular health. One consistent theme was the experience of increased energy levels and better metabolic functioning, as noted by a user who felt a boost in energy despite sleep interruptions Read Review. Additionally, users highlighted benefits such as improved skin condition and emotional health Read Review. While these anecdotal experiences shed light on the potential advantages of B-vitamins, individual results may vary, and it’s worth considering personal health conditions and consulting with a healthcare provider.
According to user reviews, combining B-complex vitamins with other supplements can enhance overall health, particularly for cardiovascular disease management. For instance, one user reported taking B-complex alongside vitamin D3, highlighting how this combination improved their cardiovascular and emotional health while easing stress and depression Read Review. Another reviewer suggested that B vitamins normalise cardiovascular functions and improve stress levels, asserting that they work synergistically within a complex for better effects Read Review.
Additionally, many users endorse consistent usage of B-complex vitamins, often noting positive outcomes that extend beyond cardiovascular health. For example, one user mentioned that, after regularly using this vitamin complex, they experienced enhanced digestion, calmer moods, and overall improved well-being Read Review. Overall, user feedback indicates that combining B-complex vitamins with other supplements can yield substantial health benefits, especially for those concerned about cardiovascular issues.
Users report a variety of experiences with Vitamin B Complex concerning its effectiveness in supporting cardiovascular health. Many reviews highlight that regular intake of B vitamins not only enhances cerebral circulation but also improves cardiovascular functions and reduces adverse symptoms associated with heart health, such as dizziness and palpitations (Read Review). For some, a daily dosage appears to be the norm, with multiple users stating they take one capsule a day, which they feel has led to measurable improvements in their overall well-being and cardiovascular health over a few weeks of consistent use (Read Review).
Moreover, users suggest that B vitamins play a crucial role in maintaining normal homocysteine levels, a factor essential for cardiovascular well-being (Read Review). The recommendation of taking B Complex as a combined supplement is echoed across reviews since they reportedly work synergistically to improve effectiveness (Read Review). Nurturing this information might encourage potential users to consider a daily regimen of B vitamins, taking care to consult healthcare providers for individual dosage recommendations.
7
Improved health overall
269 people found this helpful
A great option for a complex of B vitamins for the whole family. I started taking it immediately after receiving the parcel, and the results have been positive. We have been taking one tablet a day for two weeks, and my general health has improved, particularly regarding digestion and the cardiovascular system.
9
Reduces nervousness
1 people found this helpful
My favourite B vitamins! They significantly improve bowel function and skin condition, support emotional health, and assist in coping with stress. After a few days of taking them, I felt less nervous and more self-confident. They helped my mother with painful burrs around her nails, healing after 1.5 months of use. Wishing you health and longevity!
7.5
Stress relief
62 people found this helpful
This amazing vitamin complex has been part of my routine for two years, and I’m thrilled with the results. It improves digestion, helps manage stress, and supports both cardiovascular and immune functions. After a few weeks of use, I feel calmer and more balanced—without adverse effects. Highly recommended!
9
Calmed emotional state
7 people found this helpful
B vitamins enhance cerebral circulation, normalise cardiovascular functions, and support the immune system. After taking it consistently, I feel calmer and less reactive to stimuli. Symptoms like dizziness and palpitations have disappeared, and my digestion has improved. I will continue to take this beneficial complex.
9
Cognitive functions improved
6 people found this helpful
This B-complex was recommended by my neurologist, and as someone who has experienced multiple concussions in my younger years, I value their advice. As I'm in my early 50s, I realised the essential role B vitamins play in cognitive functions. After thorough research on its composition, I began taking it and found that my stress levels decreased, sleep improved, and memory was enhanced. I plan to continue taking this effective B-complex twice a year and hope others find my review helpful.
7.5
Pain alleviation experienced
1 people found this helpful
This complex of vitamins B was recommended by my gynecologist while I was breastfeeding. Initially concerned as I'm only 33 years old and diagnosed with arthritis, I found that after about two weeks, my energy levels increased despite sleep interruptions. Notably, I realised that my right hand no longer hurt, which was a pleasant surprise. I wholeheartedly recommend this B-complex to nursing mothers, as it has significantly improved my overall well-being. Just a note: it's better not to take it on an empty stomach!
7.5
Boosts emotional health
1 people found this helpful
The best vitamin complex! Recommended by my gynecologist, I take it with vitamin D3. I appreciate the small, easy-to-swallow capsules. B vitamins normalise the nervous and cardiovascular systems, improve bowel function and skin condition, and support emotional health, aiding stress and depression. I've found it particularly beneficial during difficult times like the Coronavirus. Highly recommend!
9
Improves sleep quality
B vitamins positively impact our body; their deficiency can lead to cardiovascular disease. They benefit the nervous system by enhancing sleep, reducing anxiety, and combatting stress. It's advisable to take these vitamins as a complex, as they improve each other's effects. We take them as a family and are very satisfied. Remember to take them with water to avoid adverse reactions. I highly recommend them.
7.5
Boosts energy levels
5 people found this helpful
B complex vitamins support energy conversion, enhancing overall tone. They are crucial for the health of the nervous system, helping to reduce fatigue, stress, and anxiety. Additionally, they are involved in metabolic processes, improving the absorption of proteins, fats, and carbohydrates, and contribute to the health of skin, hair, and nails. Vitamins B6, B9, and B12 help maintain normal homocysteine levels, essential for cardiovascular health.
9
Vitamin B6 aids heart recovery
Vitamin B6 allosterically activates AMPK to promote postischemic angiogenesis in mice.
We investigated how vitamin B6 supports heart recovery after heart attacks by promoting new blood vessel growth, known as angiogenesis. In laboratory tests, vitamin B6 improved cell migration and tubule formation, vital for forming new blood vessels.
Remarkably, long-term vitamin B6 supplementation showed significant improvements in heart function and reduced inflammation in mice following heart attacks. This suggests that vitamin B6 could be a beneficial aid for heart recovery, harnessing a specific pathway involving a protein called AMPK.
8
Folate slows artery thickness increase
Serum folate levels, but not vitamin B12, are associated with slower progression in carotid intima-media thickness in a population exposed to mandatory folic acid fortification.
We examined the link between folate and vitamin B12 levels and changes in carotid intima-media thickness (cIMT), a marker of early heart disease, over eight years in a group of 5061 adults in Brazil.
Our results suggest that higher serum folate levels are associated with a slower increase in cIMT, indicating a potential protective effect against heart disease.
However, no such benefit was observed with vitamin B12 levels. This implies that while folate may play a role in cardiovascular health, vitamin B12 might not have the same impact.
8
Niacin intake lowers mortality risks
Association of dietary niacin intake with all-cause and cardiovascular mortality: National Health and Nutrition Examination Survey (NHANES) 2003-2018.
We looked into how dietary niacin might affect mortality rates, particularly for cardiovascular disease. Analyzing data from nearly 27,000 U.S. adults over about nine years, we found that those with the highest niacin intake had a significantly lower risk of dying from any cause, as well as from heart-related issues.
Interestingly, this protective effect was more robust among those without diabetes, suggesting that niacin's benefits can vary by health condition. Our findings highlight the potential role of diet in supporting heart health.
References
Bian XY, Cui C, Zhang QY. Relationship between blood pressure variability and vitamin B level in essential hypertension. J Physiol Pharmacol. 2025;76. 10.26402/jpp.2025.1.02
Wang XQ, Yin S, Wang QW, Bai WW, Tan RH, et al. Vitamin B6 allosterically activates AMPK to promote postischemic angiogenesis in mice. Eur J Pharmacol. 2025;993:177413. 10.1016/j.ejphar.2025.177413
Song Y, Choi JE, Park JM, Kwon YJ, Hong KW, et al. Genome-Wide Approach of Gene-Nutrient Intake Interaction Study for Essential Hypertension in a Large Korean Cohort (KoGES). Nutrients. 2024;16. 10.3390/nu16234147
Palchetti CZ, Gonçalves NG, Suemoto CK, Santos IS, Lotufo PA, et al. Serum folate levels, but not vitamin B12, are associated with slower progression in carotid intima-media thickness in a population exposed to mandatory folic acid fortification. Clin Nutr ESPEN. 2025;65:144. 10.1016/j.clnesp.2024.11.034
Lin L, Chen S, Zhang C, Li L, Chen Y, et al. Association of dietary niacin intake with all-cause and cardiovascular mortality: National Health and Nutrition Examination Survey (NHANES) 2003-2018. Sci Rep. 2024;14:28313. 10.1038/s41598-024-79986-9