Reviewed By
Overview
SCIENTIFIC SCORE
Possibly Effective
Based on 7 Researches
7.7
USERS' SCORE
Moderately Good
Based on 11 Reviews
7.6
Supplement Facts
Serving Size: 2 Vegetarian Capsules
Amount Per Serving
%DV
Thiamine (vitamin B1) (as thiamine HCl)
100 mg
8333%
Riboflavin (vitamin B2) (as riboflavin and riboflavin 5'-phosphate)
75 mg
5769%
Niacin (as niacinamide and niacin)
100 mg•
625%
Vitamin B6 (as pyridoxine HCl and pyridoxal 5' phosphate)
100 mg
5882%
Folate (as L-5-methyltetrahydrofolate calcium salt)
680 mcg○
170%
Vitamin B12 (as methylcobalamin)
300 mcg
12500%
Biotin
1000 mcg
3333%
Pantothenic acid (as D-calcium pantothenate)
500 mg
10000%
Calcium (as D-calcium pantothenate, dicalcium phosphate)
50 mg
4%
Inositol
100 mg
**
PABA (para-aminobenzoic acid)
50 mg
**
Top Medical Research Studies
9
We explored whether vitamin B6 can aid heart recovery after a heart attack. Our study showed that vitamin B6 promotes angiogenesis, the formation of new blood vessels, which plays a key role in heart function recovery.
We observed that vitamin B6 enhances cell migration and tube formation in laboratory settings, as well as improves heart function in mice after a heart attack. While it shows promise, we must remember that these results are based on animal studies, and more research is needed before drawing conclusions for humans.
We observed that vitamin B6 enhances cell migration and tube formation in laboratory settings, as well as improves heart function in mice after a heart attack. While it shows promise, we must remember that these results are based on animal studies, and more research is needed before drawing conclusions for humans.
Read More
9
NAD restoration improves heart attack recovery
We explored the potential benefits of nicotinamide riboside (NR) for heart attack recovery in a study using mice. After inducing a heart attack, we administered NR daily for seven days.
The results were promising, showing a significant increase in survival rates from 61% to 92% as NR helped restore essential coenzyme levels in the heart.
Overall, our findings suggest that NR might play a protective role in heart attack management by improving heart function and reducing inflammation.
The results were promising, showing a significant increase in survival rates from 61% to 92% as NR helped restore essential coenzyme levels in the heart.
Overall, our findings suggest that NR might play a protective role in heart attack management by improving heart function and reducing inflammation.
Read More
9
We examined how benfotiamine could help protect hearts from damage due to acute myocardial infarction. In a rat model, heart injury was induced using isoproterenol. Benfotiamine was given both before and after this treatment to see if it could reduce the damage.
While we observed significant improvements in heart enzyme levels and oxidative stress markers with benfotiamine treatment, the study focused on rats and may not directly translate to humans. Overall, benfotiamine shows promise for future cardiovascular therapies, but more research is needed.
While we observed significant improvements in heart enzyme levels and oxidative stress markers with benfotiamine treatment, the study focused on rats and may not directly translate to humans. Overall, benfotiamine shows promise for future cardiovascular therapies, but more research is needed.
Read More
Most Useful Reviews
9
Heart pain improvement
I found a good complex of coenzyme forms of B vitamins. I took it due to pain in my heart area, and it helped significantly.
Read More
6
Calmed heart effects
6 people found this helpful
The stress cleared up! I take one capsule in the morning and evening with my child. I felt lighter in my body. I took it even during stressful times at work, which calmed my feelings and cleared my heart.
Read More
6
Supports heart health
Vitamin D3 offers several benefits: it aids calcium and phosphorus absorption for strong bones and teeth, supports immunity, and may have anti-inflammatory properties, combating infection and inflammation. It also positively impacts cardiovascular health by regulating blood pressure and reducing heart disease risk. Furthermore, Vitamin D3 contributes to brain health, normal muscle function, and may help regulate mood, potentially reducing depression risks.
Read More
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 7 Researches
7.7
- All Researches
9
We explored whether vitamin B6 can aid heart recovery after a heart attack. Our study showed that vitamin B6 promotes angiogenesis, the formation of new blood vessels, which plays a key role in heart function recovery.
We observed that vitamin B6 enhances cell migration and tube formation in laboratory settings, as well as improves heart function in mice after a heart attack. While it shows promise, we must remember that these results are based on animal studies, and more research is needed before drawing conclusions for humans.
We observed that vitamin B6 enhances cell migration and tube formation in laboratory settings, as well as improves heart function in mice after a heart attack. While it shows promise, we must remember that these results are based on animal studies, and more research is needed before drawing conclusions for humans.
Read More
9
NAD restoration improves heart attack recovery
We explored the potential benefits of nicotinamide riboside (NR) for heart attack recovery in a study using mice. After inducing a heart attack, we administered NR daily for seven days.
The results were promising, showing a significant increase in survival rates from 61% to 92% as NR helped restore essential coenzyme levels in the heart.
Overall, our findings suggest that NR might play a protective role in heart attack management by improving heart function and reducing inflammation.
The results were promising, showing a significant increase in survival rates from 61% to 92% as NR helped restore essential coenzyme levels in the heart.
Overall, our findings suggest that NR might play a protective role in heart attack management by improving heart function and reducing inflammation.
Read More
9
We examined how benfotiamine could help protect hearts from damage due to acute myocardial infarction. In a rat model, heart injury was induced using isoproterenol. Benfotiamine was given both before and after this treatment to see if it could reduce the damage.
While we observed significant improvements in heart enzyme levels and oxidative stress markers with benfotiamine treatment, the study focused on rats and may not directly translate to humans. Overall, benfotiamine shows promise for future cardiovascular therapies, but more research is needed.
While we observed significant improvements in heart enzyme levels and oxidative stress markers with benfotiamine treatment, the study focused on rats and may not directly translate to humans. Overall, benfotiamine shows promise for future cardiovascular therapies, but more research is needed.
Read More
8
D-pinitol shows potential heart protection
We examined the potential of D-pinitol to protect against heart damage caused by isoproterenol in Swiss albino mice. The mice were divided into eight groups, receiving various doses of D-pinitol alongside isoproterenol or other treatments.
We found that higher doses (50mg and 100mg) of D-pinitol significantly reduced markers of oxidative stress and inflammation, improving heart health. However, the lower dose (25mg) did not show any meaningful benefits. Overall, our findings suggest D-pinitol may have protective effects against heart damage.
We found that higher doses (50mg and 100mg) of D-pinitol significantly reduced markers of oxidative stress and inflammation, improving heart health. However, the lower dose (25mg) did not show any meaningful benefits. Overall, our findings suggest D-pinitol may have protective effects against heart damage.
Read More
7
We investigated how folic acid (FA) could protect against heart injury caused by isoprenaline (ISO) in rats. Over a week, the rats were given FA before being exposed to ISO, which is known to induce heart muscle damage.
The results showed that FA pretreatment helped reduce the harmful effects of ISO. It lowered markers of heart damage and oxidative stress, suggesting that FA may serve as a gentle antioxidant with potential cardiovascular benefits.
The results showed that FA pretreatment helped reduce the harmful effects of ISO. It lowered markers of heart damage and oxidative stress, suggesting that FA may serve as a gentle antioxidant with potential cardiovascular benefits.
Read More
User Reviews
USERS' SCORE
Moderately Good
Based on 11 Reviews
7.6
- All Reviews
- Positive Reviews
- Negative Reviews
9
Heart pain improvement
I found a good complex of coenzyme forms of B vitamins. I took it due to pain in my heart area, and it helped significantly.
Read More
6
Calmed heart effects
6 people found this helpful
The stress cleared up! I take one capsule in the morning and evening with my child. I felt lighter in my body. I took it even during stressful times at work, which calmed my feelings and cleared my heart.
Read More
6
Supports heart health
Vitamin D3 offers several benefits: it aids calcium and phosphorus absorption for strong bones and teeth, supports immunity, and may have anti-inflammatory properties, combating infection and inflammation. It also positively impacts cardiovascular health by regulating blood pressure and reducing heart disease risk. Furthermore, Vitamin D3 contributes to brain health, normal muscle function, and may help regulate mood, potentially reducing depression risks.
Read More
2
Heart pain reported
I took it without consultation, and after one pill, I experienced unusual heart pain, lasting for a week. I felt no desire to eat and was consistently fatigued.
Read More
7.5
Migraine relief noted
55 people found this helpful
Complete vitamin B is excellent for the nervous system and beneficial for those experiencing numbness and tingling. It supports eye health, skin, and internal organs, raises good cholesterol, lowers bad cholesterol, boosts immunity, and provides energy. I took it to alleviate my migraine attacks and felt much better. It also improved my skin and nails. The strongest package is high quality and lasts a month if taken twice a day. May God grant you happiness.
Read More
Frequently Asked Questions
6
Calmed heart effects
6 people found this helpful
The stress cleared up! I take one capsule in the morning and evening with my child. I felt lighter in my body. I took it even during stressful times at work, which calmed my feelings and cleared my heart.
0
Negative reaction experienced
I tried taking it, but on the second day, I felt unwell. My head spun, and my heart rate raced. The doctor advised me to stop this supplement, as the outcome was negative for me. Perhaps this complex isn't suitable for me. The packaging is of high quality, the size is convenient for taking, and the taste is average. The ingredients seem good, but the reaction overshadowed the positives.
4
Heart health cautiousness
1 people found this helpful
Beautiful yet dangerous. I started with this B vitamins complex due to hair loss and mood instability, which may indicate a B vitamin deficiency. I took one capsule twice daily alongside other vitamins. However, B vitamins can place stress on the heart; consult a doctor before combining them.
9
Heart pain improvement
I found a good complex of coenzyme forms of B vitamins. I took it due to pain in my heart area, and it helped significantly.
7.5
Migraine relief noted
55 people found this helpful
Complete vitamin B is excellent for the nervous system and beneficial for those experiencing numbness and tingling. It supports eye health, skin, and internal organs, raises good cholesterol, lowers bad cholesterol, boosts immunity, and provides energy. I took it to alleviate my migraine attacks and felt much better. It also improved my skin and nails. The strongest package is high quality and lasts a month if taken twice a day. May God grant you happiness.
2
Heart pain reported
I took it without consultation, and after one pill, I experienced unusual heart pain, lasting for a week. I felt no desire to eat and was consistently fatigued.
7.5
Depression relief found
Ok, firstly, reducing migraine attacks. Studies show specific B-Complex vitamins help relieve migraines, especially B6, B9, and B12. Secondly, they significantly alleviate depression and anger symptoms, with studies indicating better responses from patients taking vitamins B6 and B1. Quality ingredients lead to improved energy and overall benefit.
9
We explored whether vitamin B6 can aid heart recovery after a heart attack. Our study showed that vitamin B6 promotes angiogenesis, the formation of new blood vessels, which plays a key role in heart function recovery.
We observed that vitamin B6 enhances cell migration and tube formation in laboratory settings, as well as improves heart function in mice after a heart attack. While it shows promise, we must remember that these results are based on animal studies, and more research is needed before drawing conclusions for humans.
We observed that vitamin B6 enhances cell migration and tube formation in laboratory settings, as well as improves heart function in mice after a heart attack. While it shows promise, we must remember that these results are based on animal studies, and more research is needed before drawing conclusions for humans.
7
We investigated how folic acid (FA) could protect against heart injury caused by isoprenaline (ISO) in rats. Over a week, the rats were given FA before being exposed to ISO, which is known to induce heart muscle damage.
The results showed that FA pretreatment helped reduce the harmful effects of ISO. It lowered markers of heart damage and oxidative stress, suggesting that FA may serve as a gentle antioxidant with potential cardiovascular benefits.
The results showed that FA pretreatment helped reduce the harmful effects of ISO. It lowered markers of heart damage and oxidative stress, suggesting that FA may serve as a gentle antioxidant with potential cardiovascular benefits.
9
NAD restoration improves heart attack recovery
We explored the potential benefits of nicotinamide riboside (NR) for heart attack recovery in a study using mice. After inducing a heart attack, we administered NR daily for seven days.
The results were promising, showing a significant increase in survival rates from 61% to 92% as NR helped restore essential coenzyme levels in the heart.
Overall, our findings suggest that NR might play a protective role in heart attack management by improving heart function and reducing inflammation.
The results were promising, showing a significant increase in survival rates from 61% to 92% as NR helped restore essential coenzyme levels in the heart.
Overall, our findings suggest that NR might play a protective role in heart attack management by improving heart function and reducing inflammation.
References
- Wang XQ, Yin S, Wang QW, Bai WW, Tan RH, et al. Vitamin B6 allosterically activates AMPK to promote postischemic angiogenesis in mice. Eur J Pharmacol. 2025;993:177413. 10.1016/j.ejphar.2025.177413
- Sobot T, Bajic Z, Skrbic R, Uletilovic S, Mandic-Kovacevic N, et al. Effect of folic acid on isoprenaline-induced myocardial injury in rats. Physiol Int. 2024;111:80. 10.1556/2060.2023.00291
- Tannous C, Ghali R, Karoui A, Habeichi NJ, Amin G, et al. Nicotinamide Riboside Supplementation Restores Myocardial Nicotinamide Adenine Dinucleotide Levels, Improves Survival, and Promotes Protective Environment Post Myocardial Infarction. Cardiovasc Drugs Ther. 2024;38:1385. 10.1007/s10557-023-07525-1
- Zhang B, Dong H, Xu Y, Xu D, Sun H, et al. Associations of dietary folate, vitamin B6 and B12 intake with cardiovascular outcomes in 115664 participants: a large UK population-based cohort. Eur J Clin Nutr. 2023;77:299. 10.1038/s41430-022-01206-2
- Khan A, Iqubal A, Wasim M, Syed MA, Haque SE. D-pinitol attenuates isoproterenol-induced myocardial infarction by alleviating cardiac inflammation, oxidative stress and ultrastructural changes in Swiss albino mice. Clin Exp Pharmacol Physiol. 2022;49:1232. 10.1111/1440-1681.13703
- Evens L, Beliën H, D'Haese S, Haesen S, Verboven M, et al. Combinational Therapy of Cardiac Atrial Appendage Stem Cells and Pyridoxamine: The Road to Cardiac Repair?. Int J Mol Sci. 2021;22. 10.3390/ijms22179266
- Ahmed LA, Hassan OF, Galal O, Mansour DF, El-Khatib A. Beneficial effects of benfotiamine, a NADPH oxidase inhibitor, in isoproterenol-induced myocardial infarction in rats. PLoS One. 2020;15:e0232413. 10.1371/journal.pone.0232413
