Reviewed By
Overview
SCIENTIFIC SCORE
Possibly Effective
Based on 2 Researches
7.3
USERS' SCORE
Good
Based on 18 Reviews
8.4
Supplement Facts
Serving Size: 2 Vegetarian Capsules
Amount Per Serving
%DV
Thiamine (vitamin B1) (as thiamine HCl)
100 mg
8333%
Riboflavin (vitamin B2) (as riboflavin and riboflavin 5'-phosphate)
75 mg
5769%
Niacin (as niacinamide and niacin)
100 mg•
625%
Vitamin B6 (as pyridoxine HCl and pyridoxal 5' phosphate)
100 mg
5882%
Folate (as L-5-methyltetrahydrofolate calcium salt)
680 mcg○
170%
Vitamin B12 (as methylcobalamin)
300 mcg
12500%
Biotin
1000 mcg
3333%
Pantothenic acid (as D-calcium pantothenate)
500 mg
10000%
Calcium (as D-calcium pantothenate, dicalcium phosphate)
50 mg
4%
Inositol
100 mg
**
PABA (para-aminobenzoic acid)
50 mg
**
Top Medical Research Studies
9.5
We conducted a randomized, double-blind study to see if vitamin B complex could help older adults with nighttime leg cramps. Over three months, participants reported their cramp frequency and intensity.
The results were encouraging—86% of those taking vitamin B complex saw significant improvement, while the placebo group showed no notable changes. This suggests that vitamin B complex is a promising and safe alternative to traditional treatments like quinine, which can have unpleasant side effects.
The results were encouraging—86% of those taking vitamin B complex saw significant improvement, while the placebo group showed no notable changes. This suggests that vitamin B complex is a promising and safe alternative to traditional treatments like quinine, which can have unpleasant side effects.
Read More
5
Limited evidence for vitamin B effectiveness
We explored various treatments for leg cramps during pregnancy, including vitamin B complex. In our findings, oral vitamin B appeared to reduce the frequency and intensity of leg cramps in a small study involving 42 women.
However, the overall evidence was inconsistent and of low to very-low certainty due to design limitations and the small size of trials. Consequently, it's challenging to determine the real effectiveness and safety of vitamin B and other interventions for this common issue.
However, the overall evidence was inconsistent and of low to very-low certainty due to design limitations and the small size of trials. Consequently, it's challenging to determine the real effectiveness and safety of vitamin B and other interventions for this common issue.
Read More
Most Useful Reviews
9
Recommended for legs
100 people found this helpful
Excellent! I found this drug effective for my leg discomfort. On my doctor's advice, I started taking this complex, and I recommend it for those with similar issues.
Read More
9
Leg cramps eliminated
67 people found this helpful
I've felt a significant difference since taking vitamin B. Following a car accident and nerve injury, my burning legs at night have stopped, and my overall anxiety levels have improved markedly.
Read More
9
Effective nervous system aid
12 people found this helpful
Excellent supplements with top-quality ingredients. This B vitamin complex worked wonders for my leg pain, and I also appreciate its benefits for the nervous system. The pills are easy to swallow, enhancing their effectiveness.
Read More
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 2 Researches
7.3
- All Researches
9.5
We conducted a randomized, double-blind study to see if vitamin B complex could help older adults with nighttime leg cramps. Over three months, participants reported their cramp frequency and intensity.
The results were encouraging—86% of those taking vitamin B complex saw significant improvement, while the placebo group showed no notable changes. This suggests that vitamin B complex is a promising and safe alternative to traditional treatments like quinine, which can have unpleasant side effects.
The results were encouraging—86% of those taking vitamin B complex saw significant improvement, while the placebo group showed no notable changes. This suggests that vitamin B complex is a promising and safe alternative to traditional treatments like quinine, which can have unpleasant side effects.
Read More
5
Limited evidence for vitamin B effectiveness
We explored various treatments for leg cramps during pregnancy, including vitamin B complex. In our findings, oral vitamin B appeared to reduce the frequency and intensity of leg cramps in a small study involving 42 women.
However, the overall evidence was inconsistent and of low to very-low certainty due to design limitations and the small size of trials. Consequently, it's challenging to determine the real effectiveness and safety of vitamin B and other interventions for this common issue.
However, the overall evidence was inconsistent and of low to very-low certainty due to design limitations and the small size of trials. Consequently, it's challenging to determine the real effectiveness and safety of vitamin B and other interventions for this common issue.
Read More
User Reviews
USERS' SCORE
Good
Based on 18 Reviews
8.4
- All Reviews
- Positive Reviews
- Negative Reviews
9
Recommended for legs
100 people found this helpful
Excellent! I found this drug effective for my leg discomfort. On my doctor's advice, I started taking this complex, and I recommend it for those with similar issues.
Read More
9
Leg cramps eliminated
67 people found this helpful
I've felt a significant difference since taking vitamin B. Following a car accident and nerve injury, my burning legs at night have stopped, and my overall anxiety levels have improved markedly.
Read More
9
Effective nervous system aid
12 people found this helpful
Excellent supplements with top-quality ingredients. This B vitamin complex worked wonders for my leg pain, and I also appreciate its benefits for the nervous system. The pills are easy to swallow, enhancing their effectiveness.
Read More
9
Effective against cramps
7 people found this helpful
The combination with vitamin C helps alleviate my cramps. I've been using it for about eight days, taking two capsules daily. I've also noticed better grip and can run without my legs aching. Although my urine has turned a yellow-orange, I love this product!
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7.5
Numbness improvement
4 people found this helpful
There is an effect! A neurologist prescribed these group B vitamins, and the composition is outstanding. After 20 days, the dosage works well. My leg numbness has vanished, although I still feel some tightness in my lumbar spine. Alongside my prescribed medications, these vitamins have shown results.
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Frequently Asked Questions
9
Effective against cramps
7 people found this helpful
The combination with vitamin C helps alleviate my cramps. I've been using it for about eight days, taking two capsules daily. I've also noticed better grip and can run without my legs aching. Although my urine has turned a yellow-orange, I love this product!
10
Muscle cramps relieved
1 people found this helpful
Excellent! After using it for a month, my muscle cramps have vanished!
9
Leg cramps eliminated
67 people found this helpful
I've felt a significant difference since taking vitamin B. Following a car accident and nerve injury, my burning legs at night have stopped, and my overall anxiety levels have improved markedly.
7.5
Improved numbness
It compensates for vitamin B deficiency, although it has a high calcium content, which is not ideal. The quality is average. I used it for two weeks and observed an improvement in the numbness in my legs.
9
Nerve recovery noticed
3 people found this helpful
I've repurchased this several times. After my sciatic nerve surgery, my leg nerves felt crushed. Taking this vitamin B complex has noticeably improved my leg nerve sensations and reduced numbness. I intend to continue using it.
7.5
Good for cramps
Great! I appreciate this B vitamin complex from Life Extension. All vitamins come in bio-absorbable forms, and it’s also affordable. I take it with magnesium when cramps and numbness arise in my legs; effects usually kick in after two weeks.
5
Limited evidence for vitamin B effectiveness
We explored various treatments for leg cramps during pregnancy, including vitamin B complex. In our findings, oral vitamin B appeared to reduce the frequency and intensity of leg cramps in a small study involving 42 women.
However, the overall evidence was inconsistent and of low to very-low certainty due to design limitations and the small size of trials. Consequently, it's challenging to determine the real effectiveness and safety of vitamin B and other interventions for this common issue.
However, the overall evidence was inconsistent and of low to very-low certainty due to design limitations and the small size of trials. Consequently, it's challenging to determine the real effectiveness and safety of vitamin B and other interventions for this common issue.
9.5
We conducted a randomized, double-blind study to see if vitamin B complex could help older adults with nighttime leg cramps. Over three months, participants reported their cramp frequency and intensity.
The results were encouraging—86% of those taking vitamin B complex saw significant improvement, while the placebo group showed no notable changes. This suggests that vitamin B complex is a promising and safe alternative to traditional treatments like quinine, which can have unpleasant side effects.
The results were encouraging—86% of those taking vitamin B complex saw significant improvement, while the placebo group showed no notable changes. This suggests that vitamin B complex is a promising and safe alternative to traditional treatments like quinine, which can have unpleasant side effects.
References
- Luo L, Zhou K, Zhang J, Xu L, Yin W. Interventions for leg cramps in pregnancy. Cochrane Database Syst Rev. 2020;12:CD010655. 10.1002/14651858.CD010655.pub3
- Chan P, Huang TY, Chen YJ, Huang WP, Liu YC. Randomized, double-blind, placebo-controlled study of the safety and efficacy of vitamin B complex in the treatment of nocturnal leg cramps in elderly patients with hypertension. J Clin Pharmacol. 1998;38:1151.
