SCIENTIFIC SCORE
Moderately Effective
Based on 4 Researches
8.4
USERS' SCORE
Good
Based on 66 Reviews
8.6
Supplement Facts
Serving Size: 2 Vegetarian Capsules
Amount Per Serving
%DV
Thiamine (vitamin B1) (as thiamine HCl)
100 mg
8333%
Riboflavin (vitamin B2) (as riboflavin and riboflavin 5'-phosphate)
75 mg
5769%
Niacin (as niacinamide and niacin)
100 mg•
625%
Vitamin B6 (as pyridoxine HCl and pyridoxal 5' phosphate)
100 mg
5882%
Folate (as L-5-methyltetrahydrofolate calcium salt)
680 mcg○
170%
Vitamin B12 (as methylcobalamin)
300 mcg
12500%
Biotin
1000 mcg
3333%
Pantothenic acid (as D-calcium pantothenate)
500 mg
10000%
Calcium (as D-calcium pantothenate, dicalcium phosphate)
50 mg
4%
Inositol
100 mg
**
PABA (para-aminobenzoic acid)
50 mg
**
Top Medical Research Studies
9.5
Vitamin B1 shows promising results
Curative treatment of primary (spasmodic) dysmenorrhoea.
Highly relevant clinical findings
We assessed how effective oral vitamin B1 could be in treating primary dysmenorrhea, which causes significant pelvic pain in young women. In a robust study involving 556 participants aged 12-21 years, we administered 100 mg of vitamin B1 daily for 90 days.
The results were promising, with 87% of participants reportedly completely cured, while 8% experienced some relief. Notably, these positive outcomes persisted for two months after treatment ended, showcasing vitamin B1 as a safe and cost-effective approach to address the root cause of pelvic pain.
The results were promising, with 87% of participants reportedly completely cured, while 8% experienced some relief. Notably, these positive outcomes persisted for two months after treatment ended, showcasing vitamin B1 as a safe and cost-effective approach to address the root cause of pelvic pain.
Read More
7
Seeking effective IUD pain management
Interventions to prevent or treat heavy menstrual bleeding or pain associated with intrauterine-device use.
Evidence for vitamin B is uncertain
We analyzed various treatments for heavy menstrual bleeding and pain linked to intrauterine device (IUD) use, focusing on randomized controlled trials.
Among the 21 trials we reviewed, we found that vitamin B1 helped reduce bleeding days for Cu IUD users. However, most evidence was weak and uncertain, especially regarding other treatments like naproxen and tranexamic acid, which didn’t show clear benefits.
Overall, more robust studies are essential to confirm these findings and explore vitamin B's role further.
Among the 21 trials we reviewed, we found that vitamin B1 helped reduce bleeding days for Cu IUD users. However, most evidence was weak and uncertain, especially regarding other treatments like naproxen and tranexamic acid, which didn’t show clear benefits.
Overall, more robust studies are essential to confirm these findings and explore vitamin B's role further.
Read More
9
Effective treatment for piriformis syndrome
Effect of Mannitol plus Vitamins B in the management of patients with piriformis syndrome.
High relevance for pain management
We looked into how a combination of mannitol and B vitamins could help manage pelvic pain caused by piriformis syndrome. In our study, 22 patients received a five-day intravenous infusion of mannitol and a six-week course of B vitamins.
After treatment, significant improvements were noted in tenderness and pain levels, assessed by various clinical tests and scales. Patients reported less discomfort during rest, activities, and long sitting. Overall, the results suggest that this approach could be an effective alternative for managing piriformis syndrome.
After treatment, significant improvements were noted in tenderness and pain levels, assessed by various clinical tests and scales. Patients reported less discomfort during rest, activities, and long sitting. Overall, the results suggest that this approach could be an effective alternative for managing piriformis syndrome.
Read More
Most Useful Reviews
8.8
Pain relief noted
Reception of the complex began with a typical mistake: I failed to eat properly. After 20 minutes, I experienced a reaction to niacin: cramping stomach pain, flushing of the face, and redness of the skin on my face, neck, and hands. Fortunately, I am familiar with niacin's effects and did not panic. After drinking two glasses of water, the reaction subsided in 20 minutes. I was impressed by the drug's therapeutic effect. From the first day of taking it, I felt a surge of strength, and the spinal pain decreased. I have been taking it for two weeks now; my lips no longer feel dry, symptoms of post-COVID syndrome have diminished, my training is easier, and my sleep has improved.
Read More
9.5
Improved health overall
As a man in my 30s, I use this vitamin to enhance my overall health, mood, and well-being. After a month, I noticed an improvement in my overall body health, with no more joint pain. I feel more alert and focused, with enhanced cognitive function and energy levels.
Read More
10
Eliminated pain symptoms
Great vitamins! I have serious spine issues, including protrusions and disc herniation. After trying various vitamins over the years with no effect, I found this complex, which has alleviated my pain syndrome completely, eliminating seasonal exacerbations.
Read More
Medical Researches
SCIENTIFIC SCORE
Moderately Effective
Based on 4 Researches
8.4
- All Researches
9.5
Vitamin B1 shows promising results
Curative treatment of primary (spasmodic) dysmenorrhoea.
Highly relevant clinical findings
We assessed how effective oral vitamin B1 could be in treating primary dysmenorrhea, which causes significant pelvic pain in young women. In a robust study involving 556 participants aged 12-21 years, we administered 100 mg of vitamin B1 daily for 90 days.
The results were promising, with 87% of participants reportedly completely cured, while 8% experienced some relief. Notably, these positive outcomes persisted for two months after treatment ended, showcasing vitamin B1 as a safe and cost-effective approach to address the root cause of pelvic pain.
The results were promising, with 87% of participants reportedly completely cured, while 8% experienced some relief. Notably, these positive outcomes persisted for two months after treatment ended, showcasing vitamin B1 as a safe and cost-effective approach to address the root cause of pelvic pain.
Read More
9
Effective treatment for piriformis syndrome
Effect of Mannitol plus Vitamins B in the management of patients with piriformis syndrome.
High relevance for pain management
We looked into how a combination of mannitol and B vitamins could help manage pelvic pain caused by piriformis syndrome. In our study, 22 patients received a five-day intravenous infusion of mannitol and a six-week course of B vitamins.
After treatment, significant improvements were noted in tenderness and pain levels, assessed by various clinical tests and scales. Patients reported less discomfort during rest, activities, and long sitting. Overall, the results suggest that this approach could be an effective alternative for managing piriformis syndrome.
After treatment, significant improvements were noted in tenderness and pain levels, assessed by various clinical tests and scales. Patients reported less discomfort during rest, activities, and long sitting. Overall, the results suggest that this approach could be an effective alternative for managing piriformis syndrome.
Read More
8
Vitamin B1 showed promise for dysmenorrhea
The effects of fish oil capsules and vitamin B1 tablets on duration and severity of dysmenorrhea in students of high school in Urmia-Iran.
Relevant due to clinical trial design
We explored the effects of vitamin B1 and fish oil on dysmenorrhea in high school students. Conducting a double-blind clinical trial, we observed 240 female students divided into four groups, receiving vitamin B1, fish oil, both, or a placebo over two months.
The results showed that vitamin B1 and fish oil were similarly effective, but vitamin B1 had fewer complications and was better tolerated. Notably, the combination of vitamin B1 and fish oil provided the greatest relief from pain duration compared to the other groups.
The results showed that vitamin B1 and fish oil were similarly effective, but vitamin B1 had fewer complications and was better tolerated. Notably, the combination of vitamin B1 and fish oil provided the greatest relief from pain duration compared to the other groups.
Read More
7
Seeking effective IUD pain management
Interventions to prevent or treat heavy menstrual bleeding or pain associated with intrauterine-device use.
Evidence for vitamin B is uncertain
We analyzed various treatments for heavy menstrual bleeding and pain linked to intrauterine device (IUD) use, focusing on randomized controlled trials.
Among the 21 trials we reviewed, we found that vitamin B1 helped reduce bleeding days for Cu IUD users. However, most evidence was weak and uncertain, especially regarding other treatments like naproxen and tranexamic acid, which didn’t show clear benefits.
Overall, more robust studies are essential to confirm these findings and explore vitamin B's role further.
Among the 21 trials we reviewed, we found that vitamin B1 helped reduce bleeding days for Cu IUD users. However, most evidence was weak and uncertain, especially regarding other treatments like naproxen and tranexamic acid, which didn’t show clear benefits.
Overall, more robust studies are essential to confirm these findings and explore vitamin B's role further.
Read More
User Reviews
USERS' SCORE
Good
Based on 66 Reviews
8.6
- All Reviews
- Positive Reviews
- Negative Reviews
8.8
Pain relief noted
Reception of the complex began with a typical mistake: I failed to eat properly. After 20 minutes, I experienced a reaction to niacin: cramping stomach pain, flushing of the face, and redness of the skin on my face, neck, and hands. Fortunately, I am familiar with niacin's effects and did not panic. After drinking two glasses of water, the reaction subsided in 20 minutes. I was impressed by the drug's therapeutic effect. From the first day of taking it, I felt a surge of strength, and the spinal pain decreased. I have been taking it for two weeks now; my lips no longer feel dry, symptoms of post-COVID syndrome have diminished, my training is easier, and my sleep has improved.
Read More
9.5
Improved health overall
As a man in my 30s, I use this vitamin to enhance my overall health, mood, and well-being. After a month, I noticed an improvement in my overall body health, with no more joint pain. I feel more alert and focused, with enhanced cognitive function and energy levels.
10
Eliminated pain symptoms
Great vitamins! I have serious spine issues, including protrusions and disc herniation. After trying various vitamins over the years with no effect, I found this complex, which has alleviated my pain syndrome completely, eliminating seasonal exacerbations.
9
Mood enhancement observed
This is excellent and effectively works! I combined it with Alkar and SAM'e. Without vitamin B, my stomach ached, but once I started taking it, that pain disappeared. My urine did turn bright yellow after the first dose, which is normal, as the excess is expelled. I felt the effects of the vitamins immediately; my mood improved, my hair became shinier, and I find it easier to gain muscle mass and withstand heavy loads. I highly recommend it for both athletes and regular use.
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8.8
Anxiety alleviated
Wonderful! The effects are strong and potent. I took it to praise a friend after explaining my symptoms, and it's excellent for fatigue. It boosts physical activity greatly, so I take it after breakfast each day. My mood has improved significantly. I suffer from anxiety, tension, and difficulty in focusing, and I’ve endured pain in my upper back, shoulders, neck, and joints for years. Remarkably, that pain has eased considerably, and I highly recommend it.
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Frequently Asked Questions
No FAQs are available for this product and symptom.
