Reviewed By
Overview
SCIENTIFIC SCORE
Moderately Effective
Based on 7 Researches
8.6
USERS' SCORE
Moderately Good
Based on 36 Reviews
7.7
Supplement Facts
Serving Size: 2 Vegetarian Capsules
Amount Per Serving
%DV
Thiamine (vitamin B1) (as thiamine HCl)
100 mg
8333%
Riboflavin (vitamin B2) (as riboflavin and riboflavin 5'-phosphate)
75 mg
5769%
Niacin (as niacinamide and niacin)
100 mg•
625%
Vitamin B6 (as pyridoxine HCl and pyridoxal 5' phosphate)
100 mg
5882%
Folate (as L-5-methyltetrahydrofolate calcium salt)
680 mcg○
170%
Vitamin B12 (as methylcobalamin)
300 mcg
12500%
Biotin
1000 mcg
3333%
Pantothenic acid (as D-calcium pantothenate)
500 mg
10000%
Calcium (as D-calcium pantothenate, dicalcium phosphate)
50 mg
4%
Inositol
100 mg
**
PABA (para-aminobenzoic acid)
50 mg
**
Top Medical Research Studies
9
We investigated how benfotiamine might impact stomach ulcers in male rats. The study involved dividing 30 rats into groups receiving different treatments, including benfotiamine at varying doses, following the induction of ulcers using indomethacin.
Our results showed that benfotiamine notably decreased gastric damage and lowered inflammation markers. Specifically, doses of 100 and 200 mg/kg appeared to enhance antioxidant levels and reduce tissue damage.
However, while these findings are promising, more research is needed to fully understand the mechanisms at play and assess benfotiamine's potential for human treatment.
Our results showed that benfotiamine notably decreased gastric damage and lowered inflammation markers. Specifically, doses of 100 and 200 mg/kg appeared to enhance antioxidant levels and reduce tissue damage.
However, while these findings are promising, more research is needed to fully understand the mechanisms at play and assess benfotiamine's potential for human treatment.
Read More
8
We aimed to determine if ImproWin®, a feed additive, could help improve gastric ulcers in Standardbred and Coldblooded trotting racehorses. By conducting a randomized, double-blinded study, we assessed horses' ulcers before and after three weeks of treatment.
Our results showed a significant reduction in ulcer scores for horses treated with ImproWin®, with 78% classified as responders compared to only 54.8% in the placebo group. This indicates that ImproWin® may be beneficial for aiding the healing of gastric ulcers in affected racehorses.
Our results showed a significant reduction in ulcer scores for horses treated with ImproWin®, with 78% classified as responders compared to only 54.8% in the placebo group. This indicates that ImproWin® may be beneficial for aiding the healing of gastric ulcers in affected racehorses.
Read More
8
We examined how different doses of folic acid supplementation affect ulcer formation in rats. Male Wistar rats were treated with varying doses for 21 days while gastric ulcers were induced with indomethacin.
We found that a dose of 2 mg/kg significantly reduced gastric lesions, while a higher dose of 3 mg/kg unexpectedly worsened damage. Our results suggest that low doses of folic acid can be protective for the stomach, but high doses could pose risks.
Thus, it appears that moderation is key when considering folic acid for ulcer treatment.
We found that a dose of 2 mg/kg significantly reduced gastric lesions, while a higher dose of 3 mg/kg unexpectedly worsened damage. Our results suggest that low doses of folic acid can be protective for the stomach, but high doses could pose risks.
Thus, it appears that moderation is key when considering folic acid for ulcer treatment.
Read More
Most Useful Reviews
7.5
Quick healing noted
11 people found this helpful
I bought this to treat my son's acne, as Vitamin B is known for helping with sebum secretion. His acne, which did not improve with the dermatologist's treatment, cleared up rapidly when combined with cartilage. I also use it occasionally for mouth ulcers, and it appears to assist in quick healing.
Read More
9
No more ulcers
5 people found this helpful
This is indispensable! My daughter no longer suffers from persistent mouth ulcers since we started drinking it daily. I would give it 5 stars, but I was disappointed with the stock issues.
Read More
7.5
Accelerates healing
5 people found this helpful
This product is essential when dealing with mouth ulcers. I switched from a previous brand that made me feel ill. While it has a slight B vitamin smell, it does not bother me. It seems to help with the healing of mouth ulcers and period-related discomfort.
Read More
Medical Researches
SCIENTIFIC SCORE
Moderately Effective
Based on 7 Researches
8.6
- All Researches
9.5
We analyzed the potential connection between folic acid supplementation and gastric ulcers using data from the UK Biobank and advanced statistical methods.
Our findings suggest that folic acid may significantly lower the risk of developing gastric ulcers.
Various robust models reinforced this result, showing consistent outcomes across different analyses.
Ultimately, this research provides genetic evidence supporting the idea that receiving folic acid therapy can be beneficial in reducing gastric ulcer risk.
Our findings suggest that folic acid may significantly lower the risk of developing gastric ulcers.
Various robust models reinforced this result, showing consistent outcomes across different analyses.
Ultimately, this research provides genetic evidence supporting the idea that receiving folic acid therapy can be beneficial in reducing gastric ulcer risk.
Read More
9
We investigated how benfotiamine might impact stomach ulcers in male rats. The study involved dividing 30 rats into groups receiving different treatments, including benfotiamine at varying doses, following the induction of ulcers using indomethacin.
Our results showed that benfotiamine notably decreased gastric damage and lowered inflammation markers. Specifically, doses of 100 and 200 mg/kg appeared to enhance antioxidant levels and reduce tissue damage.
However, while these findings are promising, more research is needed to fully understand the mechanisms at play and assess benfotiamine's potential for human treatment.
Our results showed that benfotiamine notably decreased gastric damage and lowered inflammation markers. Specifically, doses of 100 and 200 mg/kg appeared to enhance antioxidant levels and reduce tissue damage.
However, while these findings are promising, more research is needed to fully understand the mechanisms at play and assess benfotiamine's potential for human treatment.
Read More
9
We explored the effects of Luffa acutangula extracts on gastric ulcers in diabetic rats. By inducing non-insulin dependent diabetes mellitus (NIDDM) and then creating gastric ulcers, we evaluated the extracts' potential for healing.
The results showed that the methanolic extract significantly boosted healing, improving protective mucosal glycoproteins and antioxidant levels. This was better than the aqueous extract and standard treatments.
Overall, Luffa acutangula appears to offer promising support for treating gastric ulcers in diabetes, highlighting its dual action in managing both conditions.
The results showed that the methanolic extract significantly boosted healing, improving protective mucosal glycoproteins and antioxidant levels. This was better than the aqueous extract and standard treatments.
Overall, Luffa acutangula appears to offer promising support for treating gastric ulcers in diabetes, highlighting its dual action in managing both conditions.
Read More
9
We explored the effectiveness of mecobalamin and vitamin E in treating recurrent oral ulcers. In a study with 58 patients, those receiving both treatments showed significantly improved healing times and reduced symptoms compared to the control group. They experienced longer periods without ulcer flare-ups and better quality of life scores. Both groups felt pain relief, but the test group had more noticeable benefits. This finding suggests that mecobalamin and vitamin E can be a valuable addition to ulcer treatment, enhancing both comfort and recovery.
Read More
8
We aimed to determine if ImproWin®, a feed additive, could help improve gastric ulcers in Standardbred and Coldblooded trotting racehorses. By conducting a randomized, double-blinded study, we assessed horses' ulcers before and after three weeks of treatment.
Our results showed a significant reduction in ulcer scores for horses treated with ImproWin®, with 78% classified as responders compared to only 54.8% in the placebo group. This indicates that ImproWin® may be beneficial for aiding the healing of gastric ulcers in affected racehorses.
Our results showed a significant reduction in ulcer scores for horses treated with ImproWin®, with 78% classified as responders compared to only 54.8% in the placebo group. This indicates that ImproWin® may be beneficial for aiding the healing of gastric ulcers in affected racehorses.
Read More
User Reviews
USERS' SCORE
Moderately Good
Based on 36 Reviews
7.7
- All Reviews
- Positive Reviews
- Negative Reviews
7.5
Quick healing noted
11 people found this helpful
I bought this to treat my son's acne, as Vitamin B is known for helping with sebum secretion. His acne, which did not improve with the dermatologist's treatment, cleared up rapidly when combined with cartilage. I also use it occasionally for mouth ulcers, and it appears to assist in quick healing.
Read More
9
No more ulcers
5 people found this helpful
This is indispensable! My daughter no longer suffers from persistent mouth ulcers since we started drinking it daily. I would give it 5 stars, but I was disappointed with the stock issues.
Read More
7.5
Accelerates healing
5 people found this helpful
This product is essential when dealing with mouth ulcers. I switched from a previous brand that made me feel ill. While it has a slight B vitamin smell, it does not bother me. It seems to help with the healing of mouth ulcers and period-related discomfort.
Read More
7.5
Fatigue reduction
4 people found this helpful
The affordability and effectiveness of this vitamin B complex are great! My mouth ulcers have improved, and so has my fatigue. I genuinely recognise the significance of high-quality B vitamins. I highly recommend it to anyone struggling with fatigue or wanting to enhance their performance.
Read More
9
Fewer occurrences
3 people found this helpful
I struggled with frequent mouth ulcers, often having multiple at once. Since taking this supplement, I've noticed a remarkable decrease in their occurrence, and any that do arise tend to heal much faster. This product has genuinely been beneficial.
Read More
Frequently Asked Questions
9
Ulcer healing notable
1 people found this helpful
Excellent! This product is popular for a reason—B vitamins reportedly enhance metabolism and benefit the skin. I take it every morning with other nutrients. Initially, I had a mouth ulcer, which usually takes over a week to heal. However, by the fourth day, it was nearly gone! My skin feels great upon waking, and I believe this B vitamin is responsible, rather than changes in my routine.
9
Fast recovery
1 people found this helpful
This is a repurchase. It effectively speeds up the recovery of oral ulcers. Taking two capsules a day, my mouth ulcers vanished by the next day—it's incredible! The packaging is very secure.
0
Disappointing results
3 people found this helpful
Unfortunately, I did not feel the effects I anticipated, and I found the cost not worth it. I hoped for relief from mouth ulcers, but I saw no improvement. Despite the popularity and many reviews, I found better value in other B complex supplements. It was somewhat disappointing.
9
Fewer occurrences
3 people found this helpful
I struggled with frequent mouth ulcers, often having multiple at once. Since taking this supplement, I've noticed a remarkable decrease in their occurrence, and any that do arise tend to heal much faster. This product has genuinely been beneficial.
7.5
Fatigue reduction
4 people found this helpful
The affordability and effectiveness of this vitamin B complex are great! My mouth ulcers have improved, and so has my fatigue. I genuinely recognise the significance of high-quality B vitamins. I highly recommend it to anyone struggling with fatigue or wanting to enhance their performance.
7.5
No acne or ulcer
9 people found this helpful
I repeat taking this all the time! Among the B vitamins, the ingredients are impressive! I often suffer from excess sebum, so I appreciate the pantothenic acid it contains. After using it, I no longer experience acne or mouth ulcers. It’s truly the best, and I buy during sales to ensure I never run out.
7.5
Quick healing noted
11 people found this helpful
I bought this to treat my son's acne, as Vitamin B is known for helping with sebum secretion. His acne, which did not improve with the dermatologist's treatment, cleared up rapidly when combined with cartilage. I also use it occasionally for mouth ulcers, and it appears to assist in quick healing.
7.5
Ulcers staying away
1 people found this helpful
I've been taking it for a month after reading about its nutritional benefits. Since using it along with D3+K2, my recurrent seborrheic dermatitis and oral ulcers haven't recurred so far. I intend to purchase more for my family and continue to see how it works long-term.
9.5
We analyzed the potential connection between folic acid supplementation and gastric ulcers using data from the UK Biobank and advanced statistical methods.
Our findings suggest that folic acid may significantly lower the risk of developing gastric ulcers.
Various robust models reinforced this result, showing consistent outcomes across different analyses.
Ultimately, this research provides genetic evidence supporting the idea that receiving folic acid therapy can be beneficial in reducing gastric ulcer risk.
Our findings suggest that folic acid may significantly lower the risk of developing gastric ulcers.
Various robust models reinforced this result, showing consistent outcomes across different analyses.
Ultimately, this research provides genetic evidence supporting the idea that receiving folic acid therapy can be beneficial in reducing gastric ulcer risk.
8
We examined how different doses of folic acid supplementation affect ulcer formation in rats. Male Wistar rats were treated with varying doses for 21 days while gastric ulcers were induced with indomethacin.
We found that a dose of 2 mg/kg significantly reduced gastric lesions, while a higher dose of 3 mg/kg unexpectedly worsened damage. Our results suggest that low doses of folic acid can be protective for the stomach, but high doses could pose risks.
Thus, it appears that moderation is key when considering folic acid for ulcer treatment.
We found that a dose of 2 mg/kg significantly reduced gastric lesions, while a higher dose of 3 mg/kg unexpectedly worsened damage. Our results suggest that low doses of folic acid can be protective for the stomach, but high doses could pose risks.
Thus, it appears that moderation is key when considering folic acid for ulcer treatment.
8
We explored the effects of nicotinamide on gastric ulcers caused by indomethacin in a laboratory setting. Using a well-established model, we compared the treatment of nicotinamide with sucralfate, a known antiulcer drug.
Our findings revealed that nicotinamide significantly reduced the severity of gastric lesions. It also helped restore vital biochemical parameters affected by the ulcer-inducing drug.
The protective effect of nicotinamide appears to stem from its ability to conserve gastric mucus and nitric oxide, improve gastric microvascular permeability, and exert antioxidant actions.
Our findings revealed that nicotinamide significantly reduced the severity of gastric lesions. It also helped restore vital biochemical parameters affected by the ulcer-inducing drug.
The protective effect of nicotinamide appears to stem from its ability to conserve gastric mucus and nitric oxide, improve gastric microvascular permeability, and exert antioxidant actions.
9
We investigated how benfotiamine might impact stomach ulcers in male rats. The study involved dividing 30 rats into groups receiving different treatments, including benfotiamine at varying doses, following the induction of ulcers using indomethacin.
Our results showed that benfotiamine notably decreased gastric damage and lowered inflammation markers. Specifically, doses of 100 and 200 mg/kg appeared to enhance antioxidant levels and reduce tissue damage.
However, while these findings are promising, more research is needed to fully understand the mechanisms at play and assess benfotiamine's potential for human treatment.
Our results showed that benfotiamine notably decreased gastric damage and lowered inflammation markers. Specifically, doses of 100 and 200 mg/kg appeared to enhance antioxidant levels and reduce tissue damage.
However, while these findings are promising, more research is needed to fully understand the mechanisms at play and assess benfotiamine's potential for human treatment.
References
- Li F, Huang F, Tang Y, Zhang F, Jiang H, et al. Causal association of folic acid supplementary therapy and gastric ulcer: a Mendelian randomisation study. Br J Nutr. 2024;132:1348. 10.1017/S0007114524002368
- Shokati Sayyad M, Khanjani MH, Amirbeik M, Seyedabadi M, Talebpour Amiri F, et al. The protective effect of benfotiamine on gastric ulcers in male rats: an experimental study. J Mol Histol. 2024;55:863. 10.1007/s10735-024-10237-x
- Hellings IR, Larsen S. ImproWin® in the treatment of gastric ulceration of the squamous mucosa in trotting racehorses. Acta Vet Scand. 2014;56:13. 10.1186/1751-0147-56-13
- Ajeigbe K, Oladejo E, Emikpe B, Asuk A, Olaleye S. The dual modulatory effect of folic acid supplementation on indomethacin-induced gastropathy in the rat. Turk J Gastroenterol. 2012;23:639.
- Pimple BP, Kadam PV, Patil MJ. Protective effect of Luffa acutangula extracts on gastric ulceration in NIDDM rats: role of gastric mucosal glycoproteins and antioxidants. Asian Pac J Trop Med. 2012;5:610. 10.1016/S1995-7645(12)60126-6
- Abdallah DM. Nicotinamide alleviates indomethacin-induced gastric ulcers: a novel antiulcer agent. Eur J Pharmacol. 2010;627:276. 10.1016/j.ejphar.2009.10.037
- Cui J, Lin W, Ma X, Wang J. Clinical Evaluation and Therapeutic Effects of Combination Treatment with Mecobalamin + Vitamin E in Recurrent Oral Ulcer. Clin Ther. 2022;44:123. 10.1016/j.clinthera.2021.10.015
