We observed that quercetin, a powerful antioxidant, plays a significant role in helping grapes withstand cold temperatures. In our study, we found that grapes exposed to low temperatures accumulate more quercetin, which in turn enhances their cold resistance.
By applying exogenous quercetin, we noted a marked improvement in the grapes' ability to endure low-temperature stress. Our research revealed that a key gene, VvFLS1, responsible for quercetin synthesis is upregulated when grapes experience cold conditions.
We also discovered that VvbZIP22, a protein that binds to the VvFLS1 promoter, is crucial for mediating this process. When we overexpressed VvbZIP22 in grapes, it resulted in higher levels of quercetin and improved cold resistance, further confirming its pivotal role in the plant's adaptation to harsh environments.
Through these findings, we highlighted the importance of quercetin in enhancing grape survival during cold spells, showcasing a vital link between plant biology and climate resilience.
Read More
8
Quercetin limits HRV1B replication
Quercetin-3-Methyl Ether Induces Early Apoptosis to Overcome HRV1B Immune Evasion, Suppress Viral Replication, and Mitigate Inflammatory Pathogenesis.
We investigated how quercetin-3-methyl ether, a natural flavonoid, impacts human rhinovirus 1B (HRV1B), which is responsible for the common cold and can worsen conditions like asthma. Our research involved testing this compound in HeLa cells to see if it could reduce viral replication and the damage associated with the virus.
In our experiments, quercetin-3-methyl ether significantly inhibited the replication of HRV1B in a concentration-dependent way, which means that higher doses produced better results. We also found that this compound enhanced early apoptosis—essentially, the process by which infected cells shut down in response to the virus—during the critical early stages of infection. This seemed to counteract HRV1B's tactics to evade the immune response.
Additionally, when we administered quercetin-3-methyl ether to mice infected with HRV1B, we observed a noteworthy reduction in viral RNA levels and inflammation in their lung tissues, suggesting a potential therapeutic effect. Our findings enhance the understanding of quercetin-3-methyl ether as a novel agent against HRV1B, pointing towards promising strategies for managing cold-related illnesses and their complications.
Read More
9
Quercetin and sucrose protect liver grafts
Preservation Efficacy of a Quercetin and Sucrose Solution for Warm Ischemically Damaged Porcine Liver Grafts.
We explored how the combination of quercetin (QE) and sucrose (Suc) improves the preservation of porcine liver grafts affected by warm ischemia followed by cold storage. Our study involved two groups of porcine livers: one preserved with the standard University of Wisconsin (UW) solution and the other with the UW solution enhanced with QE and Suc.
After preserving the livers for six hours, we subjected them to a simulated reperfusion model using saline-diluted autologous blood. To measure success, we looked at several indicators of liver health, including specific enzyme levels and histological changes.
The results were promising! The livers treated with QE and Suc showed significantly lower levels of enzymes indicating liver damage compared to those using just the UW solution. Additionally, the histological analysis revealed fewer signs of injury in the QE and Suc group, showcasing their potential in reducing cold injury in liver grafts after ischemia.
Overall, our findings indicate that adding quercetin and sucrose to the preservation solution can effectively protect liver grafts from damage caused by cold storage, especially in cases of donation after circulatory death.
Read More
Most Useful Reviews
9
Improves colds effect
100 people found this helpful
Quercetin is associated with enhanced exercise performance and reduced inflammation, blood pressure, and blood sugar levels. The typical dose is 500 mg daily. This supplement contains 29 mg of Bio-Quercetin phytosome, equating to 10 mg of quercetin but claims 50 times greater bioavailability. I used it for a cold, and it worked brilliantly. Additionally, I understand it's part of the anti-COVID protocol, so I keep it at home during these challenging times. Stay healthy!
Read More
9
Prevents colds
44 people found this helpful
It works! It keeps me healthy, with no school bus driver colds or sore throats while I take this, or that other bug going around.
Read More
9
Excellent cold relief
5 people found this helpful
Bioquercetin 30 Vegetarian Capsules is an excellent find for immune support. It has aided my recovery from colds and viral illnesses, quickly restoring my strength and alleviating inflammation. The ingredient quality is high, and my respiratory immunity remains superb. Bioquercetin acts as a true antioxidant in combating inflammation. The results are impressive, and it has a lovely taste, making it an essential part of my health regimen.
We explored how the combination of quercetin (QE) and sucrose (Suc) improves the preservation of porcine liver grafts affected by warm ischemia followed by cold storage. Our study involved two groups of porcine livers: one preserved with the standard University of Wisconsin (UW) solution and the other with the UW solution enhanced with QE and Suc.
After preserving the livers for six hours, we subjected them to a simulated reperfusion model using saline-diluted autologous blood. To measure success, we looked at several indicators of liver health, including specific enzyme levels and histological changes.
The results were promising! The livers treated with QE and Suc showed significantly lower levels of enzymes indicating liver damage compared to those using just the UW solution. Additionally, the histological analysis revealed fewer signs of injury in the QE and Suc group, showcasing their potential in reducing cold injury in liver grafts after ischemia.
Overall, our findings indicate that adding quercetin and sucrose to the preservation solution can effectively protect liver grafts from damage caused by cold storage, especially in cases of donation after circulatory death.
Read More
8
Quercetin limits HRV1B replication
Quercetin-3-Methyl Ether Induces Early Apoptosis to Overcome HRV1B Immune Evasion, Suppress Viral Replication, and Mitigate Inflammatory Pathogenesis.
We investigated how quercetin-3-methyl ether, a natural flavonoid, impacts human rhinovirus 1B (HRV1B), which is responsible for the common cold and can worsen conditions like asthma. Our research involved testing this compound in HeLa cells to see if it could reduce viral replication and the damage associated with the virus.
In our experiments, quercetin-3-methyl ether significantly inhibited the replication of HRV1B in a concentration-dependent way, which means that higher doses produced better results. We also found that this compound enhanced early apoptosis—essentially, the process by which infected cells shut down in response to the virus—during the critical early stages of infection. This seemed to counteract HRV1B's tactics to evade the immune response.
Additionally, when we administered quercetin-3-methyl ether to mice infected with HRV1B, we observed a noteworthy reduction in viral RNA levels and inflammation in their lung tissues, suggesting a potential therapeutic effect. Our findings enhance the understanding of quercetin-3-methyl ether as a novel agent against HRV1B, pointing towards promising strategies for managing cold-related illnesses and their complications.
Read More
8
Quercetin boosts grape cold resistance
VvbZIP22 regulates quercetin synthesis to enhances cold resistance in grape.
We observed that quercetin, a powerful antioxidant, plays a significant role in helping grapes withstand cold temperatures. In our study, we found that grapes exposed to low temperatures accumulate more quercetin, which in turn enhances their cold resistance.
By applying exogenous quercetin, we noted a marked improvement in the grapes' ability to endure low-temperature stress. Our research revealed that a key gene, VvFLS1, responsible for quercetin synthesis is upregulated when grapes experience cold conditions.
We also discovered that VvbZIP22, a protein that binds to the VvFLS1 promoter, is crucial for mediating this process. When we overexpressed VvbZIP22 in grapes, it resulted in higher levels of quercetin and improved cold resistance, further confirming its pivotal role in the plant's adaptation to harsh environments.
Through these findings, we highlighted the importance of quercetin in enhancing grape survival during cold spells, showcasing a vital link between plant biology and climate resilience.
Read More
User Reviews
USERS' SCORE
Good
Based on 71 Reviews
8.1
All Reviews
Positive Reviews
Negative Reviews
9
Improves colds effect
100 people found this helpful
Quercetin is associated with enhanced exercise performance and reduced inflammation, blood pressure, and blood sugar levels. The typical dose is 500 mg daily. This supplement contains 29 mg of Bio-Quercetin phytosome, equating to 10 mg of quercetin but claims 50 times greater bioavailability. I used it for a cold, and it worked brilliantly. Additionally, I understand it's part of the anti-COVID protocol, so I keep it at home during these challenging times. Stay healthy!
Read More
9
Prevents colds
44 people found this helpful
It works! It keeps me healthy, with no school bus driver colds or sore throats while I take this, or that other bug going around.
Read More
9
Excellent cold relief
5 people found this helpful
Bioquercetin 30 Vegetarian Capsules is an excellent find for immune support. It has aided my recovery from colds and viral illnesses, quickly restoring my strength and alleviating inflammation. The ingredient quality is high, and my respiratory immunity remains superb. Bioquercetin acts as a true antioxidant in combating inflammation. The results are impressive, and it has a lovely taste, making it an essential part of my health regimen.
Read More
9
Effective against cold
3 people found this helpful
This strong quercetin is effective against viruses. I use it at the initial signs of a cold, and typically, by the following day, I feel fine.
Read More
10
No more colds
1 people found this helpful
The capsules are small and seem easily absorbed. Since taking them, I find I no longer catch colds!
Cold is a term that refers to a state of low temperature, often associated with a perceptibly chilly environment or the sensation of being cool to the touch. Scientifically, cold is relative to the presence and movement of heat, which is a measure of energy within matter. In everyday terms, we experience cold through weather changes, such as during winter months, and it can also be described in the context of specific temperature ranges – for example, temperatures below 32 degrees Fahrenheit (0 degrees Celsius) generally signify freezing conditions, which can impact outdoor activities, personal comfort, and various ecological systems.
Moreover, the sensation of cold is not solely dependent on temperature; factors like humidity and wind chill can enhance the feeling of coldness. When discussing cold in terms of human health, prolonged exposure to cold conditions can lead to hypothermia or frostbite if body heat is not effectively maintained. Hence, it's crucial to dress appropriately and take necessary precautions during colder months to prevent adverse effects. Understanding the concept of cold can help individuals better prepare for seasonal changes and ensure their comfort and safety.
Quercetin is a naturally occurring flavonoid that is found in a variety of fruits, vegetables, and grains. Known for its antioxidant properties, quercetin is believed to help combat oxidative stress in the body, which can contribute to various health issues. You can commonly find it in foods such as apples, onions, berries, and citrus fruits, as well as in leafy greens. This makes it a popular dietary supplement among health enthusiasts looking to enhance their overall wellness.
Beyond its antioxidant capacity, quercetin is also being researched for its potential anti-inflammatory effects and benefits for immune support. Some studies suggest that it may help reduce allergy symptoms and improve exercise performance by decreasing muscle fatigue. With its wide range of potential health benefits, quercetin is often marketed as a natural remedy for various ailments, although it’s essential to consult a healthcare professional before starting any new supplement regimen to ensure its safety and effectiveness for your specific needs.
Quercetin is a natural flavonoid found in a variety of fruits, vegetables, and grains, and has garnered attention for its potential health benefits, particularly its anti-inflammatory and antioxidant properties. Research suggests that quercetin may help bolster the immune system, which could be beneficial in reducing the severity or duration of cold symptoms. While some studies indicate it may have a role in alleviating symptoms of respiratory infections, including the common cold, the evidence is not definitive.
It's important to note that while quercetin supplements are available and may offer potential benefits, they should not be seen as a replacement for traditional cold remedies or treatments. If you're considering adding quercetin to your regimen, it’s wise to consult with a healthcare professional, especially if you have existing health conditions or are taking other medications. Overall, maintaining a well-rounded diet rich in fruits and vegetables—many of which contain quercetin—along with good hygiene practices, remains a fundamental approach to preventing colds.
Based on user reviews, the time it typically takes to notice results from taking quercetin for colds can vary, but many users report experiencing improvements quite rapidly. For instance, one user mentions that they felt significantly better by the following day after taking it at the first signs of a cold (Read Review). Others describe the supplement as aiding in quicker recovery and alleviating symptoms effectively, suggesting that noticeable improvements can occur within a few days of starting the regimen.
Additionally, some users have experienced sustained benefits over a longer period, seeing continued improvement in their immune function after regular use over weeks (Read Review). Overall, while individual experiences may differ, many find quercetin serves as a quick-acting support for cold symptoms, with effects apparent typically within a day or more.
Recent research indicates that quercetin, a natural flavonoid, may be beneficial in combating cold viruses. A study demonstrated that quercetin-3-methyl ether significantly inhibited the replication of human rhinovirus 1B (HRV1B), a leading cause of the common cold, in laboratory settings. Not only was viral replication reduced in cell cultures, but the administration of this compound to infected mice resulted in lowered viral RNA levels and reduced inflammation in lung tissues. These findings suggest that quercetin may serve as a novel therapeutic agent against cold-related illnesses, highlighting its potential in early-stage interventions [1].
While the research primarily points to quercetin's efficacy against viral infections, it is essential to note that existing studies do not directly explore its effects on human cold symptoms in a clinical setting. The data encourages further exploration into how quercetin can be incorporated into supplement regimens aimed at preventing or alleviating the common cold. Overall, the scientific support leans positively towards quercetin's potential benefits against cold viruses, making it a supplement worth consideration for those seeking natural remedies [1].
Based on user reviews, many individuals report substantial improvements in their symptoms when taking quercetin, particularly for colds and viral infections. Users indicate that quercetin not only helps alleviate symptoms quickly but also plays a significant role in supporting overall immunity. For instance, one reviewer noted feeling "fine by the following day" after taking it at the first signs of a cold (Read Review), while another mentioned that it helped them "quickly regain strength after illness" and reduced inflammation (Read Review).
Additionally, several users emphasize its effectiveness in preventing further complications and managing chronic conditions, such as allergies or respiratory issues. One user shared that they "no longer catch colds" after taking quercetin regularly (Read Review), and another pointed out its role in enhancing physical performance and reducing inflammation (Read Review). Overall, while individual experiences may vary, the feedback suggests that quercetin is a promising supplement for those looking to boost their immune function and mitigate cold symptoms effectively.
Based on user reviews, many individuals have successfully combined quercetin with other supplements to enhance their effectiveness in addressing cold symptoms. For instance, a user highlights the positive effects of combining quercetin with zinc, stating that this duo effectively alleviates discomfort and prevents complications during a cold (Read Review). Additionally, another user recommends pairing quercetin with vitamin D, vitamin C, and zinc as a robust anti-cold remedy, noting the high quality of the product in this combination (Read Review). Further reinforcing this, several reviews indicate strong benefits when quercetin is used alongside other immune-supportive ingredients like propolis and monolaurin for dealing with viral infections in general (Read Review).
Users have reported that these combinations not only mitigate cold symptoms but also promote overall immune function. The synergistic benefits are observed with users feeling quicker recoveries and experiencing fewer instances of illness when employing quercetin alongside these other supplements (Read Review). Overall, while many users find quercetin effective on its own, the added support from other supplements appears to enhance its benefits, making it a versatile component in cold management strategies.
Based on user reviews, the typical effective dose for Quercetin in treating colds seems to hover around 500 mg daily. Many users emphasize the importance of starting treatment at the initial signs of a cold, with several reports indicating that combining Quercetin with zinc enhances its effectiveness in alleviating symptoms and boosting recovery (review id='cd29d7b6-0708-4c7e-bf0f-a98f589af237', review id='b1ba1712-1b0e-4b16-a077-627981475319'). Additionally, users have noted that while they found Quercetin to be beneficial during cold and flu seasons, it is advisable to take it for a limited duration, around 4 to 6 weeks, to avoid prolonged use Read Review.
Users also report that products containing formulations like Bio-Quercetin, which enhance bioavailability, have led to favorable experiences in symptom relief Read Review. Overall, the consensus among reviewers suggests that a daily dosage of around 500 mg, especially when paired with other supportive nutrients like zinc, appears to effectively support immune function and hasten recovery from colds.
9
Effective against cold
3 people found this helpful
This strong quercetin is effective against viruses. I use it at the initial signs of a cold, and typically, by the following day, I feel fine.
9
Effective for cold
I like Quercetin; it is truly effective against cold symptoms. I took it for about a month and noticed benefits for my immune system. However, be cautious and do not take it for too long—only 4-6 weeks. Its small size makes it easy to ingest.
9
Regained strength
Bioquercetin 30 vegetarian capsules is a true find. It greatly aids colds and viral infections. It helped me quickly regain strength after illness and reduce inflammation. The quality of ingredients is high, and respiratory immunity is well-supported. Bioquercetin is a potent antioxidant that effectively combats inflammation. Excellent results and pleasant taste—it has become an essential part of my health regimen.
10
No more colds
1 people found this helpful
The capsules are small and seem easily absorbed. Since taking them, I find I no longer catch colds!
9
Improves colds effect
100 people found this helpful
Quercetin is associated with enhanced exercise performance and reduced inflammation, blood pressure, and blood sugar levels. The typical dose is 500 mg daily. This supplement contains 29 mg of Bio-Quercetin phytosome, equating to 10 mg of quercetin but claims 50 times greater bioavailability. I used it for a cold, and it worked brilliantly. Additionally, I understand it's part of the anti-COVID protocol, so I keep it at home during these challenging times. Stay healthy!
9
Cold and allergy relief
1 people found this helpful
This is my go-to purchase. In case of a cold, quercetin and zinc together are an effective duo for alleviating discomfort and preventing complications. I also use quercetin for seasonal allergies, and it is significantly helpful.
9
High-quality anti-cold remedy
This is a fine product that works superbly when combined with vitamin D, zinc, and vitamin C as an anti-cold remedy. I appreciate the high quality.
7.5
Alleviates cold symptoms
1 people found this helpful
It's beneficial during colds or viral infections. It works quite well, easing inflammation and improving my condition. You might combine it with propolis, monolaurin, cordyceps for COVID, or serrapeptase. Thank you, iHerb! The size, taste of the capsules, and packaging do not bother me; is that the real reason I buy supplements? They have always come well packaged, and these are delicious—difficult to resist!
7.5
Improves immunity
I find this product excellent; it has notably improved our family's immunity, with fewer instances of illness or colds. Quercetin combines with phytosomes, allowing for quick absorption, approximately 50 times more than traditional versions, which helps in strengthening the immune system and reducing oxidative stress.
8
Quercetin limits HRV1B replication
Quercetin-3-Methyl Ether Induces Early Apoptosis to Overcome HRV1B Immune Evasion, Suppress Viral Replication, and Mitigate Inflammatory Pathogenesis.
We investigated how quercetin-3-methyl ether, a natural flavonoid, impacts human rhinovirus 1B (HRV1B), which is responsible for the common cold and can worsen conditions like asthma. Our research involved testing this compound in HeLa cells to see if it could reduce viral replication and the damage associated with the virus.
In our experiments, quercetin-3-methyl ether significantly inhibited the replication of HRV1B in a concentration-dependent way, which means that higher doses produced better results. We also found that this compound enhanced early apoptosis—essentially, the process by which infected cells shut down in response to the virus—during the critical early stages of infection. This seemed to counteract HRV1B's tactics to evade the immune response.
Additionally, when we administered quercetin-3-methyl ether to mice infected with HRV1B, we observed a noteworthy reduction in viral RNA levels and inflammation in their lung tissues, suggesting a potential therapeutic effect. Our findings enhance the understanding of quercetin-3-methyl ether as a novel agent against HRV1B, pointing towards promising strategies for managing cold-related illnesses and their complications.
References
Song JH, Mun SH, Mishra S, Kim SR, Yang H, et al. Quercetin-3-Methyl Ether Induces Early Apoptosis to Overcome HRV1B Immune Evasion, Suppress Viral Replication, and Mitigate Inflammatory Pathogenesis. Biomol Ther (Seoul). 2025;33:388. 10.4062/biomolther.2024.204
Liu G, Zhang Z, Tian Y, Yang J, Xu X, et al. VvbZIP22 regulates quercetin synthesis to enhances cold resistance in grape. Plant Sci. 2025;350:112293. 10.1016/j.plantsci.2024.112293
Otani M, Ishii D, Iwata H, Satake Y, Okada Y, et al. Preservation Efficacy of a Quercetin and Sucrose Solution for Warm Ischemically Damaged Porcine Liver Grafts. Transplant Proc. 2023;55:2212. 10.1016/j.transproceed.2023.07.031