Intake of 25-Hydroxyvitamin D3 Reduces Duration and Severity of Upper Respiratory Tract Infection: A Randomized, Double-Blind, Placebo-Controlled, Parallel Group Comparison Study.
We explored how 25-hydroxyvitamin D3 (25OHD), a form of vitamin D, influences upper respiratory tract infections (URTIs), commonly known as colds. In a carefully designed clinical study, we followed 428 participants aged 45 to 74 over a 16-week period. They were randomly assigned to receive either 10 μg of 25OHD daily or a placebo, all while maintaining a double-blind setup to ensure accurate results.
Our findings revealed that those who took 25OHD had reduced duration and severity of their cold symptoms. Participants reported improvements in their overall quality of life during the bouts of URTI. By tracking the health of the participants through surveys designed to measure cold symptoms, we gathered valuable data that indicates vitamin D3 could play a helpful role in managing colds.
This suggests that incorporating vitamin D3 into our diets may be beneficial when we catch a cold, potentially leading to a quicker recovery. It’s a promising avenue for anyone looking to ease the discomfort and duration of these frustrating infections.
Read More
8
Vitamin D enhances cold resilience
Influence of Vitamin D Supplementation by Simulated Sunlight or Oral D3 on Respiratory Infection during Military Training.
We delved into the effects of vitamin D on cold symptoms among military recruits during their training. In two comprehensive studies, we observed over 1,600 military recruits to see how their vitamin D levels impacted their likelihood of upper respiratory tract infections (URTIs) throughout the seasons.
In the first study, only 21% of recruits were found to have sufficient vitamin D levels during winter. Notably, those with adequate vitamin D were 40% less likely to experience URTIs compared to those who were deficient. Each URTI typically caused three missed training days, indicating a significant impact on their training schedules.
Following this, we conducted a randomized controlled trial with 250 men simulating sunlight exposure or providing oral vitamin D3 supplementation. Our goal was to see how both methods affected overall vitamin D levels and, subsequently, URTI symptoms. Remarkably, both strategies successfully brought participants to sufficient vitamin D levels. Compared to those who received a placebo, those getting vitamin D3 experienced a 15% reduction in the severity of cold symptoms and a 36% decrease in the number of days with URTI.
Interestingly, we found that both methods—simulated sunlight and oral supplementation—were equally effective, and neither had a significant impact on specific immune response markers.
Read More
8
Vitamin D3 aids cold symptom relief
Intake of 25-Hydroxyvitamin D May Reduce the Severity of Upper Respiratory Tract Infection: Post hoc Analysis of a Randomized, Double-Blind, Placebo-Controlled, Parallel Group Comparison Study.
We explored the potential benefits of vitamin D3, specifically 25-hydroxyvitamin D, on cold symptoms among people with insufficient or deficient levels of this essential nutrient. The study was well-designed, involving a randomized, double-blind, placebo-controlled method where participants received either 10 μg of vitamin D3 or a placebo over 16 weeks.
During the study, we used a tool called the Wisconsin Upper Respiratory Symptom Survey-21, which helped us collect data on physical signs and symptoms of upper respiratory tract infections (URTI). We observed that participants who took vitamin D3 experienced significantly lower scores for symptoms like runny nose, sneezing, and head congestion compared to those on a placebo. Additionally, their overall quality of life, except for the ability to breathe easily, improved when they were taking vitamin D3.
However, it's important to note that the number of cold occurrences and the use of other medications, like antibiotics and pain relievers, showed no significant difference between the two groups. Overall, our findings suggest that adequate intake of vitamin D3 can indeed help reduce certain cold symptoms and enhance quality of life when a cold strikes.
Read More
Most Useful Reviews
9
Improved health
97 people found this helpful
I switched to this vitamin last week, and the improvements were noticeable already. My mood is better, energy levels are higher, and I haven’t caught any colds or other illnesses since starting this! I'm pleased with the risk-free trial.
Read More
9
Prevents cold onset
61 people found this helpful
This isn’t my first order. At the first sign of a cold, I follow the Kornilova scheme, which prevents me from getting sick further. My family and I take these vitamins together, and I appreciate that it contains vitamin K2 due to its necessary dosage of 5000. The small capsules are easy to swallow. I recommend these to everyone; I reorder them constantly.
Read More
9
Protection against colds
8 people found this helpful
No colds! I have been taking Vitamin D & K, along with a 5,000 IU soft gel D3 daily since having bowel cancer five years ago. I have had no colds since then, attributing my resilience to these.
We delved into the effects of vitamin D on cold symptoms among military recruits during their training. In two comprehensive studies, we observed over 1,600 military recruits to see how their vitamin D levels impacted their likelihood of upper respiratory tract infections (URTIs) throughout the seasons.
In the first study, only 21% of recruits were found to have sufficient vitamin D levels during winter. Notably, those with adequate vitamin D were 40% less likely to experience URTIs compared to those who were deficient. Each URTI typically caused three missed training days, indicating a significant impact on their training schedules.
Following this, we conducted a randomized controlled trial with 250 men simulating sunlight exposure or providing oral vitamin D3 supplementation. Our goal was to see how both methods affected overall vitamin D levels and, subsequently, URTI symptoms. Remarkably, both strategies successfully brought participants to sufficient vitamin D levels. Compared to those who received a placebo, those getting vitamin D3 experienced a 15% reduction in the severity of cold symptoms and a 36% decrease in the number of days with URTI.
Interestingly, we found that both methods—simulated sunlight and oral supplementation—were equally effective, and neither had a significant impact on specific immune response markers.
Read More
8
Vitamin D3 aids cold symptom relief
Intake of 25-Hydroxyvitamin D May Reduce the Severity of Upper Respiratory Tract Infection: Post hoc Analysis of a Randomized, Double-Blind, Placebo-Controlled, Parallel Group Comparison Study.
We explored the potential benefits of vitamin D3, specifically 25-hydroxyvitamin D, on cold symptoms among people with insufficient or deficient levels of this essential nutrient. The study was well-designed, involving a randomized, double-blind, placebo-controlled method where participants received either 10 μg of vitamin D3 or a placebo over 16 weeks.
During the study, we used a tool called the Wisconsin Upper Respiratory Symptom Survey-21, which helped us collect data on physical signs and symptoms of upper respiratory tract infections (URTI). We observed that participants who took vitamin D3 experienced significantly lower scores for symptoms like runny nose, sneezing, and head congestion compared to those on a placebo. Additionally, their overall quality of life, except for the ability to breathe easily, improved when they were taking vitamin D3.
However, it's important to note that the number of cold occurrences and the use of other medications, like antibiotics and pain relievers, showed no significant difference between the two groups. Overall, our findings suggest that adequate intake of vitamin D3 can indeed help reduce certain cold symptoms and enhance quality of life when a cold strikes.
Read More
8
Vitamin D3 aids cold recovery
Intake of 25-Hydroxyvitamin D3 Reduces Duration and Severity of Upper Respiratory Tract Infection: A Randomized, Double-Blind, Placebo-Controlled, Parallel Group Comparison Study.
We explored how 25-hydroxyvitamin D3 (25OHD), a form of vitamin D, influences upper respiratory tract infections (URTIs), commonly known as colds. In a carefully designed clinical study, we followed 428 participants aged 45 to 74 over a 16-week period. They were randomly assigned to receive either 10 μg of 25OHD daily or a placebo, all while maintaining a double-blind setup to ensure accurate results.
Our findings revealed that those who took 25OHD had reduced duration and severity of their cold symptoms. Participants reported improvements in their overall quality of life during the bouts of URTI. By tracking the health of the participants through surveys designed to measure cold symptoms, we gathered valuable data that indicates vitamin D3 could play a helpful role in managing colds.
This suggests that incorporating vitamin D3 into our diets may be beneficial when we catch a cold, potentially leading to a quicker recovery. It’s a promising avenue for anyone looking to ease the discomfort and duration of these frustrating infections.
Read More
User Reviews
USERS' SCORE
Good
Based on 66 Reviews
8.3
All Reviews
Positive Reviews
Negative Reviews
9
Improved health
97 people found this helpful
I switched to this vitamin last week, and the improvements were noticeable already. My mood is better, energy levels are higher, and I haven’t caught any colds or other illnesses since starting this! I'm pleased with the risk-free trial.
Read More
9
Prevents cold onset
61 people found this helpful
This isn’t my first order. At the first sign of a cold, I follow the Kornilova scheme, which prevents me from getting sick further. My family and I take these vitamins together, and I appreciate that it contains vitamin K2 due to its necessary dosage of 5000. The small capsules are easy to swallow. I recommend these to everyone; I reorder them constantly.
Read More
9
Protection against colds
8 people found this helpful
No colds! I have been taking Vitamin D & K, along with a 5,000 IU soft gel D3 daily since having bowel cancer five years ago. I have had no colds since then, attributing my resilience to these.
Read More
10
No colds
1 people found this helpful
In my opinion, this dietary supplement should be taken regularly by everyone. My whole family takes it, and fortunately, neither we nor the children had any colds throughout the winter. I like this manufacturer because their products contain high doses of vitamin D, K for better absorption, and iodine.
Read More
10
Family support
1 people found this helpful
Excellent value for money! During a cold, it helped my entire family! I would recommend it.
Cold is a term that refers to a state of low temperature, often associated with a perceptibly chilly environment or the sensation of being cool to the touch. Scientifically, cold is relative to the presence and movement of heat, which is a measure of energy within matter. In everyday terms, we experience cold through weather changes, such as during winter months, and it can also be described in the context of specific temperature ranges – for example, temperatures below 32 degrees Fahrenheit (0 degrees Celsius) generally signify freezing conditions, which can impact outdoor activities, personal comfort, and various ecological systems.
Moreover, the sensation of cold is not solely dependent on temperature; factors like humidity and wind chill can enhance the feeling of coldness. When discussing cold in terms of human health, prolonged exposure to cold conditions can lead to hypothermia or frostbite if body heat is not effectively maintained. Hence, it's crucial to dress appropriately and take necessary precautions during colder months to prevent adverse effects. Understanding the concept of cold can help individuals better prepare for seasonal changes and ensure their comfort and safety.
Vitamin D3 K2 is a supplement that combines two vital nutrients: vitamin D3 (cholecalciferol) and vitamin K2 (menaquinone). Vitamin D3 is crucial for maintaining healthy bones and immune function, as it helps the body absorb calcium, which is essential for bone strength. It can be obtained through sunlight exposure, certain foods, and supplements. On the other hand, vitamin K2 plays a significant role in directing calcium to the bones and teeth while preventing it from depositing in the arteries and soft tissues, thus promoting cardiovascular health and overall well-being.
The synergy between vitamin D3 and K2 is particularly important because they work together to ensure that calcium is utilized effectively in the body. While vitamin D3 boosts calcium absorption, vitamin K2 ensures that this calcium is deposited properly in the bones rather than accumulating in the arteries. This combination is believed to support bone density, cardiovascular health, and overall vitality. Many health professionals recommend considering a D3 and K2 supplement, especially for individuals who may be at risk of deficiency or those who live in areas with limited sunlight exposure. Always consult a healthcare provider before starting any new supplement regimen.
Based on user reviews, many people report noticing improvements relatively quickly after starting to take the supplement for cold prevention. For instance, some users claim to see noticeable results within just a week of taking the vitamin, including increased energy levels and mood enhancements, as well as a general decrease in cold occurrences Read Review. Others mention that after beginning their regimen, they experienced significantly fewer colds, often attributing their resilience to consistent use of the supplement Read Review.
Several reviews suggest that while some users report immediate effects, such as improved mood and immune support, it might take a few weeks to fully notice the benefits related to cold prevention Read Review. In summary, while individual responses may vary, users appear to find substantial benefits within a week or two of consistent use.
Vitamin D3 supplementation has gained attention for its potential benefits in managing cold symptoms, supported by several scientific studies. One research study involving military recruits demonstrated that those with sufficient vitamin D levels were 40% less likely to experience upper respiratory tract infections (URTIs) compared to those who were deficient. Additionally, a randomized controlled trial within the same research indicated that participants who received oral vitamin D3 experienced a 15% reduction in the severity of cold symptoms and a 36% decrease in the number of days suffering from URTIs, compared to those receiving a placebo [1].
Further supporting this, a separate study found that individuals with insufficient vitamin D levels had significantly lower cold symptom scores when taking daily doses of vitamin D3 compared to those on a placebo. Participants reported improvements in physical symptoms such as runny noses and sneezing, alongside an enhanced overall quality of life. Another clinical trial echoed these findings, showing that vitamin D3 can reduce both the duration and severity of cold symptoms. The cumulative evidence indicates that adequate intake of Vitamin D3 may play a beneficial role in alleviating cold symptoms, making it a supplement worth considering during cold season [2][3].
Users report a variety of improvements in their symptoms after using the vitamin D and K supplement. Many have noted a significant boost in energy levels and mood, often experiencing these benefits within just a week of starting the regimen Read Review. A recurring theme among reviewers is a marked reduction in the incidence of colds and illnesses, with several individuals claiming to have gone months or even years without catching a cold since incorporating this supplement into their daily routine Read ReviewRead Review.
Additionally, several users highlighted improvements in overall immune function and recovery times, particularly noting that symptoms, when they did occur, were milder and resolved more quickly Read ReviewRead Review. It's important to remember that individual results can vary, and while many users have experienced significant health benefits, others may have different responses to the supplement. Overall, the consensus among reviewers is that this vitamin combination strongly supports overall well-being and immune health.
Users have reported various experiences when combining this vitamin D and K supplement with other supplements to enhance cold prevention and immune support. For instance, some reviewers emphasized the effectiveness of pairing this supplement with zinc and vitamin C, which they believe boosts overall immunity significantly. One user noted an impressive year-long absence of colds since adopting this regimen, further highlighting the importance of proper supplement combinations in cold management Read Review. Another reviewer praised the favorable effects of taking vitamin D alongside vitamin C, stating it effectively bolstered their immune system and enhanced recovery Read Review.
Additionally, some users advocate for combining vitamin D with other micronutrients, such as quercetin, for quicker recovery from colds Read Review. Others highlight the advantage of taking vitamin D with vitamin K for better absorption, reinforcing the idea that synergy among supplements can lead to improved health outcomes, especially during cold seasons Read Review. Overall, while users respond positively to this vitamin combination alone, many have found additional benefits through thoughtful supplement stacking for enhanced immune support.
When it comes to managing cold symptoms, research suggests that Vitamin D3 can be an effective ally. In studies conducted involving military recruits as well as older adults, taking a daily dose of 10 μg (or 400 IU) of Vitamin D3 showed noteworthy benefits. For instance, one study found that participants who supplemented with Vitamin D3 experienced a 15% reduction in the severity of cold symptoms and a significant improvement in their quality of life during bouts of upper respiratory tract infections (URTIs) [1].
Moreover, another study highlighted that daily intake of 10 μg of Vitamin D3 not only reduced the severity of symptoms but also shortened the overall duration of those cold symptoms [3]. The combination of Vitamin D3 and K2 in supplementation can potentially enhance its effectiveness, although specific research directly addressing the optimal combined dosage for treating colds remains limited. Overall, maintaining sufficient levels of Vitamin D3 can provide relief and support during cold seasons.
9
Improved health
97 people found this helpful
I switched to this vitamin last week, and the improvements were noticeable already. My mood is better, energy levels are higher, and I haven’t caught any colds or other illnesses since starting this! I'm pleased with the risk-free trial.
9
Protection against colds
8 people found this helpful
No colds! I have been taking Vitamin D & K, along with a 5,000 IU soft gel D3 daily since having bowel cancer five years ago. I have had no colds since then, attributing my resilience to these.
9
No cold or illness
After switching to this vitamin supplement last week, the results were noticeable within a short time. My mood and energy levels have significantly improved. Moreover, I have not experienced any colds or illnesses since starting this regimen. My research on this product has only confirmed my satisfaction, especially with its risk-free trial. I’m genuinely happy with the impact it has had on my overall well-being.
9
No cold since taking
Great! Almost the only variant on the market with a good proportion of both vitamin D and K. I've been purchasing this product for 2-3 years and am really satisfied with the results. I have not had a cold since then! My vitamin D levels have been tested three times - always in the upper reference range! I will continue to buy this product.
9
Milder symptoms
I have repeatedly purchased this product and notice fewer colds after taking it. My cold symptoms tend to be mild, and I recover swiftly. I will continue taking it.
10
Increased resistance
1 people found this helpful
This is a must-have! I recommend taking this along with zinc and vitamin C, plus omega-3 after breakfast, and vitamin B about an hour later—this set boosts immunity in these unstable times. Since I started this regimen in August 2020, I haven't had any colds for a year. Blood tests show no excess vitamins either. I also got this for my elderly parents and brother to enhance their immunity. Remember, don’t skimp on your health!
8
Boosted energy
1 people found this helpful
This excellent vitamin D combined with K provides a surge of energy and vitality. My teeth and joints have improved due to better calcium absorption. During the cold season, I combine it with vitamin C, effectively boosting my immune system and recovery.
7.5
Cold recovery
I regularly take vitamin D as I seldom see the sun. The addition of vitamin K aids in absorbing vitamin D. I'm consistently pleased with the quality. During a cold, I used a trio of vitamin D, zinc, and quercetin, and it truly helped me recover quicker.
7.5
Reduced illness frequency
I trust this manufacturer and take it during the off-season colds. I’ve noticed we get ill less often. Additionally, I take vitamin D with vitamin K for better absorption.
8
Vitamin D enhances cold resilience
Influence of Vitamin D Supplementation by Simulated Sunlight or Oral D3 on Respiratory Infection during Military Training.
We delved into the effects of vitamin D on cold symptoms among military recruits during their training. In two comprehensive studies, we observed over 1,600 military recruits to see how their vitamin D levels impacted their likelihood of upper respiratory tract infections (URTIs) throughout the seasons.
In the first study, only 21% of recruits were found to have sufficient vitamin D levels during winter. Notably, those with adequate vitamin D were 40% less likely to experience URTIs compared to those who were deficient. Each URTI typically caused three missed training days, indicating a significant impact on their training schedules.
Following this, we conducted a randomized controlled trial with 250 men simulating sunlight exposure or providing oral vitamin D3 supplementation. Our goal was to see how both methods affected overall vitamin D levels and, subsequently, URTI symptoms. Remarkably, both strategies successfully brought participants to sufficient vitamin D levels. Compared to those who received a placebo, those getting vitamin D3 experienced a 15% reduction in the severity of cold symptoms and a 36% decrease in the number of days with URTI.
Interestingly, we found that both methods—simulated sunlight and oral supplementation—were equally effective, and neither had a significant impact on specific immune response markers.
8
Vitamin D3 aids cold symptom relief
Intake of 25-Hydroxyvitamin D May Reduce the Severity of Upper Respiratory Tract Infection: Post hoc Analysis of a Randomized, Double-Blind, Placebo-Controlled, Parallel Group Comparison Study.
We explored the potential benefits of vitamin D3, specifically 25-hydroxyvitamin D, on cold symptoms among people with insufficient or deficient levels of this essential nutrient. The study was well-designed, involving a randomized, double-blind, placebo-controlled method where participants received either 10 μg of vitamin D3 or a placebo over 16 weeks.
During the study, we used a tool called the Wisconsin Upper Respiratory Symptom Survey-21, which helped us collect data on physical signs and symptoms of upper respiratory tract infections (URTI). We observed that participants who took vitamin D3 experienced significantly lower scores for symptoms like runny nose, sneezing, and head congestion compared to those on a placebo. Additionally, their overall quality of life, except for the ability to breathe easily, improved when they were taking vitamin D3.
However, it's important to note that the number of cold occurrences and the use of other medications, like antibiotics and pain relievers, showed no significant difference between the two groups. Overall, our findings suggest that adequate intake of vitamin D3 can indeed help reduce certain cold symptoms and enhance quality of life when a cold strikes.
8
Vitamin D3 aids cold recovery
Intake of 25-Hydroxyvitamin D3 Reduces Duration and Severity of Upper Respiratory Tract Infection: A Randomized, Double-Blind, Placebo-Controlled, Parallel Group Comparison Study.
We explored how 25-hydroxyvitamin D3 (25OHD), a form of vitamin D, influences upper respiratory tract infections (URTIs), commonly known as colds. In a carefully designed clinical study, we followed 428 participants aged 45 to 74 over a 16-week period. They were randomly assigned to receive either 10 μg of 25OHD daily or a placebo, all while maintaining a double-blind setup to ensure accurate results.
Our findings revealed that those who took 25OHD had reduced duration and severity of their cold symptoms. Participants reported improvements in their overall quality of life during the bouts of URTI. By tracking the health of the participants through surveys designed to measure cold symptoms, we gathered valuable data that indicates vitamin D3 could play a helpful role in managing colds.
This suggests that incorporating vitamin D3 into our diets may be beneficial when we catch a cold, potentially leading to a quicker recovery. It’s a promising avenue for anyone looking to ease the discomfort and duration of these frustrating infections.
References
Harrison SE, Oliver SJ, Kashi DS, Carswell AT, Edwards JP, et al. Influence of Vitamin D Supplementation by Simulated Sunlight or Oral D3 on Respiratory Infection during Military Training. Med Sci Sports Exerc. 2021;53:1505. 10.1249/MSS.0000000000002604
Shimizu Y, Ito Y, Uotsu N, Yui K. Intake of 25-Hydroxyvitamin D May Reduce the Severity of Upper Respiratory Tract Infection: Post hoc Analysis of a Randomized, Double-Blind, Placebo-Controlled, Parallel Group Comparison Study. Nutrients. 2020;12. 10.3390/nu12123769
Shimizu Y, Ito Y, Yui K, Egawa K, Orimo H. Intake of 25-Hydroxyvitamin D3 Reduces Duration and Severity of Upper Respiratory Tract Infection: A Randomized, Double-Blind, Placebo-Controlled, Parallel Group Comparison Study. J Nutr Health Aging. 2018;22:491. 10.1007/s12603-017-0952-x