'
Life Extension MacuGuard Ocular Support
SCIENTIFIC SCORE
Moderately Effective
Based on 8 Researches
8.4
USERS' SCORE
Good
Based on 22 Reviews
8.7
Supplement Facts
Serving Size: 1 Capsule
Amount Per Serving
%DV
Vitamin D3 (as cholecalciferol)
125 mcg
625%
Vitamin K activity from:Vitamin K1 (as phytonadione)Vitamin K2 (as menaquinone-4)Vitamin K2 (as trans menaquinone-7)
2,100 mcg1,000 mcg1,000 mcg100 mcg
1,750%
Iodine [from Sea-Iodine™ Complex Blend (organic kelp and bladderwrack extracts, potassium iodide)]
1,000 mcg
667%

Top Medical Research Studies

9
Iodine reduces rhinovirus infections
Interruption of experimental rhinovirus transmission.
Highly relevant to cold treatments
We explored the effectiveness of 2% aqueous iodine in preventing infections caused by rhinoviruses, the culprits behind the common cold. In a controlled setting, volunteers had their fingers treated with iodine before being exposed to the virus. Remarkably, none of the eight participants who received the iodine treatment became infected immediately afterwards. In contrast, all of the seven volunteers treated with a placebo did get infected.

We also noticed that when exposure occurred two hours after iodine application, only one out of ten volunteers fell victim to the virus, whereas six out of ten in the placebo group became ill. The difference was notable, though not quite statistically significant. Additionally, tests showed virus presence in only 11% of hand washes from those who used iodine, compared to 41% from the placebo group, suggesting that iodine may substantially reduce virus contamination on hands.

Overall, these findings indicate that using iodine could be an effective strategy in preventing common cold infections, especially right after treatment. It seems that applying iodine to our hands may serve as a protective measure against rhinovirus, significantly reducing the chances of getting sick.
Read More
8
Vitamin D3 improves cold symptoms
Intake of 25-Hydroxyvitamin D3 Reduces Duration and Severity of Upper Respiratory Tract Infection: A Randomized, Double-Blind, Placebo-Controlled, Parallel Group Comparison Study.
High relevance to vitamin D3 effects
We conducted a thorough investigation into how 25-hydroxyvitamin D3, commonly referred to as vitamin D3, impacts upper respiratory tract infections (URTIs), particularly the common cold. This study was carried out as a randomized, double-blind, placebo-controlled trial, engaging 428 participants, all aged between 45 and 74, across three clinics in Japan.

Participants were divided into two groups, with one receiving a daily dose of 10 μg of vitamin D3, while the other took a placebo for 16 weeks. Our findings highlighted that those who took vitamin D3 experienced a reduction in the duration of their upper respiratory symptoms, as well as a decrease in severity and improvement in their quality of life during illness.

Overall, our results indicate that supplementing with vitamin D3 might be a proactive step in handling the discomforts associated with common colds. This simple addition to one's daily routine could lead to a notably better experience when facing URTIs, providing a hopeful outlook for those looking for relief from their symptoms.
Read More
8
Vitamin D helps reduce cold symptoms
Intake of 25-Hydroxyvitamin D May Reduce the Severity of Upper Respiratory Tract Infection: Post hoc Analysis of a Randomized, Double-Blind, Placebo-Controlled, Parallel Group Comparison Study.
Direct assessment of vitamin D effects
We conducted an insightful analysis to see how 25-hydroxyvitamin D, often referred to as 25OHD, impacts symptoms of upper respiratory tract infections, commonly known as colds. In this randomized, placebo-controlled study, participants with insufficient or deficient levels of vitamin D were given either a daily dose of 10 µg of 25OHD or a placebo over a period of 16 weeks. This setup allowed us to objectively compare the effects of vitamin D treatment.

Our findings were quite telling. We observed that those receiving 25OHD had significantly lower scores for physical symptoms such as runny nose, sneezing, and head congestion compared to the placebo group. Additionally, quality of life scores improved across the board for the vitamin D group, with the exception of one aspect—breathing easily.

However, it's important to note that while 25OHD intake seemed to alleviate some symptoms, there was no significant difference in the overall number of cold episodes experienced or the usage of medications like antibiotics and pain relievers. This suggests that while 25-hydroxyvitamin D can help reduce certain nasal symptoms and improve quality of life, it may not prevent colds or decrease their frequency.
Read More

Most Useful Reviews

8.8
Consistent health improvement
Prior to this supplement, I frequently suffered from the common cold and sore throats. After starting on Vitamins D and K for immune support, I have not had any signs of colds or flu for over 18 months, despite family illness.
Read More
9.5
Mood boost noted
I've only taken this vitamin for a week, but I'm already noticing an improvement in my mood. I've experienced no colds or illness so far. I'm quite satisfied with the trial period product and its effects.
Read More
8.8
Preventive against colds
I frequently order these vitamins. At the first sign of a common cold, I follow the Kornilova scheme, and it prevents illness from worsening. My family also benefits from its content of Vitamin K2 at 5000 units. The capsules are small and easy to swallow. I constantly reorder and recommend it to everyone.
Read More

Medical Researches

SCIENTIFIC SCORE
Moderately Effective
Based on 8 Researches
8.4
  • All Researches
9
Vitamin D3 may aid immunity
Immunological aspects of sport nutrition.
Limited evidence on colds
We delved into the question of how vitamin D3 supplementation might influence occurrences of the common cold, particularly among athletes. There is growing interest within the sports nutrition community about whether certain nutrients can help maintain a healthy immune response during periods of intense physical training.

Our findings suggest that vitamin D3 is particularly important for immune function. Various studies indicate that adequate levels of vitamin D can assist in reducing the incidence and duration of infections, including colds, not just in athletes but in the general population, too. However, many individuals may experience low vitamin D levels, especially during the winter months when sunlight exposure is limited.

While the overall evidence suggests a beneficial role for vitamin D in immune health, we recognize that direct evidence specifically linking vitamin D3 to a reduction in the common cold is somewhat limited. Nonetheless, the importance of maintaining sufficient vitamin D status can't be overlooked in the broader context of overall health and resilience against infections.

In conclusion, while vitamin D3 shows promise in boosting our immunity, further focused research specifically addressing its impact on the common cold is needed for clearer insights.
Read More
9
Vitamin D3 shows potential benefits
[Dietary efficacy of a micronutrient combination in patients with recurrent upper respiratory tract infections. Results of a placebo-controlled doubleblind study.].
Significant context for colds
We explored the potential benefits of a special combination of micronutrients, which includes vitamin D3, in helping individuals who frequently suffer from upper respiratory tract infections, commonly known as the common cold. This study involved 192 participants and was conducted as a randomized, placebo-controlled, double-blind trial over 16 weeks.

Our findings were promising, revealing that those in the group receiving the micronutrient blend reported significant improvements in their cold symptoms compared to those who received a placebo. Specifically, individuals with severe symptoms showed a notable reduction in their common cold scores, indicating that vitamin D3, along with other vitamins and minerals, could play a role in enhancing overall immune response.

Furthermore, younger participants in the active group were less likely to miss work due to cold episodes. Those who had low levels of vitamin D3 or vitamin C at the start of the study also experienced fewer episodes of illness, underscoring the importance of maintaining adequate levels of these nutrients.

While there was no isolated analysis of vitamin D3’s effectiveness, the overall improvement in the group suggests that this micronutrient, among others, could truly contribute to better health during cold season.
Read More
9
PVP-I gargle effectively reduces infections
Evaluation of the bactericidal activity of povidone-iodine and commercially available gargle preparations.
Study shows useful preventive measures
We explored the effects of povidone-iodine (PVP-I) gargle on the prevention of common colds and influenza by comparing its bactericidal activity with that of other commercially available gargles. In our study, we tested PVP-I against chlorhexidine gluconate and cetylpyridinium chloride using different strains of bacteria. This involved both lab tests measuring bactericidal effects and practical assessments of how effective these gargles were in reducing oral bacteria counts after use.

Interestingly, our findings revealed that PVP-I not only demonstrated the highest bactericidal rate but also significantly reduced the number of bacteria in the mouth after gargling. Additionally, we conducted a survey to gauge users' feelings about each gargle, which added a personal touch to our investigation.

We also looked at real-world impacts by encouraging middle school students to use the PVP-I gargle, which seemed to reduce their absence rates due to colds and flu. This suggests that regular use of this particular gargle may aid in preventing common respiratory infections, making it a beneficial practice for both individuals and communities.
Read More
9
Iodine reduces rhinovirus infections
Interruption of experimental rhinovirus transmission.
Highly relevant to cold treatments
We explored the effectiveness of 2% aqueous iodine in preventing infections caused by rhinoviruses, the culprits behind the common cold. In a controlled setting, volunteers had their fingers treated with iodine before being exposed to the virus. Remarkably, none of the eight participants who received the iodine treatment became infected immediately afterwards. In contrast, all of the seven volunteers treated with a placebo did get infected.

We also noticed that when exposure occurred two hours after iodine application, only one out of ten volunteers fell victim to the virus, whereas six out of ten in the placebo group became ill. The difference was notable, though not quite statistically significant. Additionally, tests showed virus presence in only 11% of hand washes from those who used iodine, compared to 41% from the placebo group, suggesting that iodine may substantially reduce virus contamination on hands.

Overall, these findings indicate that using iodine could be an effective strategy in preventing common cold infections, especially right after treatment. It seems that applying iodine to our hands may serve as a protective measure against rhinovirus, significantly reducing the chances of getting sick.
Read More
8
Vitamin D helps reduce cold symptoms
Intake of 25-Hydroxyvitamin D May Reduce the Severity of Upper Respiratory Tract Infection: Post hoc Analysis of a Randomized, Double-Blind, Placebo-Controlled, Parallel Group Comparison Study.
Direct assessment of vitamin D effects
We conducted an insightful analysis to see how 25-hydroxyvitamin D, often referred to as 25OHD, impacts symptoms of upper respiratory tract infections, commonly known as colds. In this randomized, placebo-controlled study, participants with insufficient or deficient levels of vitamin D were given either a daily dose of 10 µg of 25OHD or a placebo over a period of 16 weeks. This setup allowed us to objectively compare the effects of vitamin D treatment.

Our findings were quite telling. We observed that those receiving 25OHD had significantly lower scores for physical symptoms such as runny nose, sneezing, and head congestion compared to the placebo group. Additionally, quality of life scores improved across the board for the vitamin D group, with the exception of one aspect—breathing easily.

However, it's important to note that while 25OHD intake seemed to alleviate some symptoms, there was no significant difference in the overall number of cold episodes experienced or the usage of medications like antibiotics and pain relievers. This suggests that while 25-hydroxyvitamin D can help reduce certain nasal symptoms and improve quality of life, it may not prevent colds or decrease their frequency.
Read More

User Reviews

USERS' SCORE
Good
Based on 22 Reviews
8.7
  • All Reviews
  • Positive Reviews
  • Negative Reviews
8.8
Consistent health improvement
Prior to this supplement, I frequently suffered from the common cold and sore throats. After starting on Vitamins D and K for immune support, I have not had any signs of colds or flu for over 18 months, despite family illness.
9.5
Mood boost noted
I've only taken this vitamin for a week, but I'm already noticing an improvement in my mood. I've experienced no colds or illness so far. I'm quite satisfied with the trial period product and its effects.
8.8
Preventive against colds
I frequently order these vitamins. At the first sign of a common cold, I follow the Kornilova scheme, and it prevents illness from worsening. My family also benefits from its content of Vitamin K2 at 5000 units. The capsules are small and easy to swallow. I constantly reorder and recommend it to everyone.
Read More
9.5
Immunity from colds
I take one dose of Vitamin D&K and a 5,000 IU D3 soft gel daily. Ever since my bowel cancer diagnosis five years ago, I have experienced no colds. I attribute this immunity to consistent supplementation; I used to contract colds annually, but not anymore.
9.5
Vitality restored
This Vitamin D is exceptional! It revitalised my life. Deficiency leads to various issues, including frequent colds. My dosage restores my energy and mood, keeping illness at bay. Additionally, the Vitamin K prevents adverse effects associated with taking Vitamin D alone. I highly recommend this product!
Read More
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