' 
SCIENTIFIC SCORE
Moderately Effective
Based on 1 Research
8
USERS' SCORE
Good
Based on 3 Reviews
8.7
Supplement Facts
Serving Size: 1 Capsule
Amount Per Serving
%DV
Vitamin D3 (as cholecalciferol)
125 mcg
625%
Vitamin K activity from:Vitamin K1 (as phytonadione)Vitamin K2 (as menaquinone-4)Vitamin K2 (as trans menaquinone-7)
2,100 mcg1,000 mcg1,000 mcg100 mcg
1,750%
Iodine [from Sea-Iodine™ Complex Blend (organic kelp and bladderwrack extracts, potassium iodide)]
1,000 mcg
667%
Top Medical Research Studies
8
Vitamin D3's role in immunity
The differential effects of 1,25-dihydroxyvitamin D3 on Salmonella-induced interleukin-8 and human beta-defensin-2 in intestinal epithelial cells.
Relevant but indirect correlation
We investigated how 1,25-dihydroxyvitamin D3, a form of vitamin D, affects our body's response to Salmonella, one of the most common causes of foodborne illnesses. In our research, we found that when we pretreated intestinal epithelial cells (IECs) with vitamin D3, it managed to lower the levels of interleukin-8, a pro-inflammatory substance triggered by Salmonella, while boosting the production of human beta-defensin-2, an important antimicrobial peptide.
This fascinating finding means that vitamin D3 can help balance the immune response to infection. On one hand, it reduces harmful inflammation, while on the other, it enhances our body's natural defense mechanisms. We observed that vitamin D3 also promotes the activity of a protein known as NOD2, which plays a critical role in immune signaling. This suggests that vitamin D3 not only tempers inflammation but also encourages the production of defenses against Salmonella.
The implications of our research are significant, especially for those prone to severe food poisoning from Salmonella. By enhancing the immune system without ramping up inflammation, vitamin D3 may offer a promising avenue for treatment strategies against invasive Salmonella infections, providing a dual approach to improving health outcomes for those affected by foodborne illnesses.
This fascinating finding means that vitamin D3 can help balance the immune response to infection. On one hand, it reduces harmful inflammation, while on the other, it enhances our body's natural defense mechanisms. We observed that vitamin D3 also promotes the activity of a protein known as NOD2, which plays a critical role in immune signaling. This suggests that vitamin D3 not only tempers inflammation but also encourages the production of defenses against Salmonella.
The implications of our research are significant, especially for those prone to severe food poisoning from Salmonella. By enhancing the immune system without ramping up inflammation, vitamin D3 may offer a promising avenue for treatment strategies against invasive Salmonella infections, providing a dual approach to improving health outcomes for those affected by foodborne illnesses.
Read More
Most Useful Reviews
9.5
Improved health overall
I consistently recommend this product to my family: my daughter, mother, husband, and I each take it for varied health issues. My daughter, after using vitamin D and iodine for over 7 months, has seen significant hormonal improvements and lower infection rates. Previously persistent warts on her foot vanished during this time. My husband, who uses high doses of vitamin D when feeling unwell, has also noticed fewer illnesses. My mother, aged 78, hasn’t experienced any deterioration in health while maintaining strong bones. I've personally noticed a drop in colds and viruses. My slightly deformed feet haven't worsened, prompting me to advise others against surgery for minor issues. Each family member benefits differently from this vitamin. The best results require patience, as deficiencies take time to correct.
Read More
9.5
Energy boost experienced
I began using this product earlier in the year, and despite constant rain and low immunity, I managed to avoid illness while working long hours. Initially, I took two capsules for two weeks, then one daily, always in the morning, as iodine isn’t absorbed well after noon. I paired it with healthy fats like avocado toast and fish. Fortunately, there were no negative side effects from the iodine, even at higher initial doses. The small capsules are easy to swallow, and I’m definitely planning to use it again.
Read More
8.8
Mood improvement noted
I've spent a significant amount of time considering this vitamin D supplement, thoroughly researching reviews. It’s crucial to take vitamin D with vitamin K, as absorption is poor without it. Living in areas lacking sunlight leads to widespread deficiencies, affecting mental health negatively. I personally take Adam multivitamins daily, which contain vitamin D, and I also use this product every other day. Within two weeks, I've felt a notable improvement in my mood and productivity. I intend to continue using it through the winter months when sunlight is scarce.
Read More
Medical Researches
SCIENTIFIC SCORE
Moderately Effective
Based on 1 Research
8
- All Researches
8
Vitamin D3's role in immunity
The differential effects of 1,25-dihydroxyvitamin D3 on Salmonella-induced interleukin-8 and human beta-defensin-2 in intestinal epithelial cells.
Relevant but indirect correlation
We investigated how 1,25-dihydroxyvitamin D3, a form of vitamin D, affects our body's response to Salmonella, one of the most common causes of foodborne illnesses. In our research, we found that when we pretreated intestinal epithelial cells (IECs) with vitamin D3, it managed to lower the levels of interleukin-8, a pro-inflammatory substance triggered by Salmonella, while boosting the production of human beta-defensin-2, an important antimicrobial peptide.
This fascinating finding means that vitamin D3 can help balance the immune response to infection. On one hand, it reduces harmful inflammation, while on the other, it enhances our body's natural defense mechanisms. We observed that vitamin D3 also promotes the activity of a protein known as NOD2, which plays a critical role in immune signaling. This suggests that vitamin D3 not only tempers inflammation but also encourages the production of defenses against Salmonella.
The implications of our research are significant, especially for those prone to severe food poisoning from Salmonella. By enhancing the immune system without ramping up inflammation, vitamin D3 may offer a promising avenue for treatment strategies against invasive Salmonella infections, providing a dual approach to improving health outcomes for those affected by foodborne illnesses.
This fascinating finding means that vitamin D3 can help balance the immune response to infection. On one hand, it reduces harmful inflammation, while on the other, it enhances our body's natural defense mechanisms. We observed that vitamin D3 also promotes the activity of a protein known as NOD2, which plays a critical role in immune signaling. This suggests that vitamin D3 not only tempers inflammation but also encourages the production of defenses against Salmonella.
The implications of our research are significant, especially for those prone to severe food poisoning from Salmonella. By enhancing the immune system without ramping up inflammation, vitamin D3 may offer a promising avenue for treatment strategies against invasive Salmonella infections, providing a dual approach to improving health outcomes for those affected by foodborne illnesses.
Read More
User Reviews
USERS' SCORE
Good
Based on 3 Reviews
8.7
- All Reviews
- Positive Reviews
- Negative Reviews
9.5
Improved health overall
I consistently recommend this product to my family: my daughter, mother, husband, and I each take it for varied health issues. My daughter, after using vitamin D and iodine for over 7 months, has seen significant hormonal improvements and lower infection rates. Previously persistent warts on her foot vanished during this time. My husband, who uses high doses of vitamin D when feeling unwell, has also noticed fewer illnesses. My mother, aged 78, hasn’t experienced any deterioration in health while maintaining strong bones. I've personally noticed a drop in colds and viruses. My slightly deformed feet haven't worsened, prompting me to advise others against surgery for minor issues. Each family member benefits differently from this vitamin. The best results require patience, as deficiencies take time to correct.
Read More
9.5
Energy boost experienced
I began using this product earlier in the year, and despite constant rain and low immunity, I managed to avoid illness while working long hours. Initially, I took two capsules for two weeks, then one daily, always in the morning, as iodine isn’t absorbed well after noon. I paired it with healthy fats like avocado toast and fish. Fortunately, there were no negative side effects from the iodine, even at higher initial doses. The small capsules are easy to swallow, and I’m definitely planning to use it again.
Read More
8.8
Mood improvement noted
I've spent a significant amount of time considering this vitamin D supplement, thoroughly researching reviews. It’s crucial to take vitamin D with vitamin K, as absorption is poor without it. Living in areas lacking sunlight leads to widespread deficiencies, affecting mental health negatively. I personally take Adam multivitamins daily, which contain vitamin D, and I also use this product every other day. Within two weeks, I've felt a notable improvement in my mood and productivity. I intend to continue using it through the winter months when sunlight is scarce.
Read More
