We conducted a rigorous study to explore how vitamin D3 supplementation might influence headaches in people suffering from migraines. By utilizing a well-structured, placebo-controlled, double-blind design, we included 80 participants with episodic migraines, assigning them either a daily dose of vitamin D3 or a placebo for 12 weeks.
After the study, we observed significant improvements in those receiving vitamin D3. Participants reported fewer headache days each month, shorter headache durations, and less severe pain overall. They also used fewer pain relievers compared to those on placebo, showcasing the potential benefit of vitamin D3 in managing migraine symptoms.
Our findings suggest that vitamin D3 not only aids in reducing headache frequency but may also play a role in addressing inflammation, as evidenced by reduced levels of certain inflammatory markers in the blood. This highlights its possible therapeutic value for migraine sufferers, indicating that a daily dose could make a meaningful difference in their lives.
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8
Vitamin D3 reduces migraine frequency
A randomized, double-blinded, placebo-controlled, parallel trial of vitamin D supplementation in adult patients with migraine.
We conducted a rigorous study to determine whether vitamin D3 supplementation could help improve the lives of adults suffering from migraines. Our approach involved a well-structured, randomized, double-blinded, placebo-controlled trial, which included 36 women and 12 men, aged between 18 to 65 years.
Participants underwent a 4-week baseline period before being randomly assigned to receive either 100 μg/day of D3 vitamin or a placebo for 24 weeks. Throughout the study, we kept track of migraine attacks and various symptoms through self-reported diaries, logging important details like the frequency and severity of their migraines.
Our findings were quite promising. Those taking D3 vitamin experienced fewer migraine days compared to those on the placebo, suggesting that vitamin D3 could serve as an effective preventative treatment for migraine management. However, we noted that further studies with larger sample sizes would be beneficial to solidify these claims and fully understand the potential role of vitamin D3 in migraine prevention.
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7
Vitamin D deficiency and headaches
Vitamin D Deficiency in Patients With Chronic Tension-Type Headache: A Case-Control Study.
We conducted a study to explore the relationship between chronic tension-type headaches (CTTH) and vitamin D levels in the body. By comparing one hundred adults suffering from CTTH to one hundred healthy individuals, we looked for possible connections between headache prevalence and vitamin D deficiency.
Our findings revealed that those with CTTH had significantly lower serum levels of vitamin D compared to the healthy controls. Specifically, the average vitamin D level in CTTH patients was just 14.7 ng/mL, while the controls averaged 27.4 ng/mL. Additionally, 71% of those with CTTH were considered vitamin D deficient, compared to only 25% of the control group.
We also observed that patients suffering from these headaches reported higher rates of related issues, like musculoskeletal pain and muscle weakness. For those who were vitamin D deficient, these problems appeared even more pronounced, suggesting that a lack of vitamin D might exacerbate headache symptoms.
Overall, our study highlights a noteworthy association between vitamin D levels and chronic tension-type headaches. However, further intervention studies are necessary to determine if vitamin D supplementation can serve as an effective treatment option for these patients.
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Most Useful Reviews
9
Headache relief
Okay, my favourite brand! It already includes Vitamins D3 and K2 together. The headache has stopped, the drowsiness has gone, and my skin and nails are gradually improving. I appreciate the composition, free from artificial additives, soy, and flavourings. Excellent effect without side effects.
Read More
9
Headache disappearance
It can safely be called a vitamin for women's health. The balanced composition with vitamin K enhances the absorption of vitamin D. After completing the course, fatigue, lethargy, and headaches vanished. It also fortifies the immune system.
Read More
9
Headaches gone
My mother and I took it daily for almost a month. Both of our headaches disappeared, our blood pressure normalised, and our nerves calmed. I recommend this brand to everyone; it genuinely helps.
We conducted a study to explore the effectiveness of simvastatin combined with vitamin D3 in preventing headaches for adults suffering from episodic migraines. The study involved 57 participants who were randomly assigned either the active treatment or a placebo for 24 weeks, following a 12-week baseline period.
Our findings revealed that those taking simvastatin and vitamin D3 experienced a meaningful reduction in the number of migraine days compared to those on the placebo. In fact, participants on the active treatment saw their migraine days decrease by an average of 8 days during the first 12 weeks, and 9 days during the subsequent weeks, with a statistically significant difference that supports the treatment's effectiveness.
It's also worth mentioning that 25% of the participants on simvastatin and vitamin D3 achieved at least a 50% reduction in migraine days at 12 weeks, which increased to 29% by 24 weeks. This is in stark contrast to just 3% of participants in the placebo group. Importantly, the occurrence of side effects was similar between the groups, suggesting that the treatment was well-tolerated.
Overall, we observed a promising potential for simvastatin and vitamin D3 as a preventative option for those grappling with chronic migraines, while also considering the broader health implications regarding vascular health.
Read More
9
Pediatric migraine treatment effectiveness
The Impact of Vitamin D Supplementation to Topiramate Therapy on Pediatric Migraine Prophylaxis.
We aimed to explore the effects of vitamin D3 supplementation on headaches in children undergoing treatment with topiramate for migraines. In a carefully designed double-blind clinical trial, we involved children aged 5 to 14 years who were experiencing migraines. Participants were randomly divided into two groups: one received topiramate with vitamin D3 supplements, while the other received topiramate along with a placebo.
Over four months, we noted significant enhancements in the group taking vitamin D3. Specifically, this group showed a greater reduction in the frequency of headache attacks and overall migraine disability compared to the placebo group. We observed that 76% of children in the vitamin D3 group reported good responses to the treatment, compared to only 54% in the placebo group.
Importantly, while both groups experienced side effects, those in the vitamin D3 group reported fewer issues. Thus, we found vitamin D3 supplementation to be a well-tolerated and effective addition to topiramate therapy for managing pediatric migraines.
Read More
9
Giant Cell Arteritis Treatment Insights
A Case Report of Post COVID19 Giant Cell Arteritis and Polymyalgia Rheumatica With Visual Loss.
In exploring the treatment for headaches associated with post-COVID-19 giant cell arteritis and polymyalgia rheumatica, we observed that vitamin D3 was included alongside more traditional therapies. This was part of a comprehensive treatment approach that also involved pulse methylprednisolone and perineural injection therapy.
While the main focus of treatment appeared to be on corticosteroids and pain management strategies, the exact effect of vitamin D3 on headache relief remains unclear. Since the headaches notably persisted through early treatment stages and improved significantly after additional intervention, we can't conclusively state the efficacy of vitamin D3 in alleviating headache symptoms from this case alone.
It's worth noting that individual responses to treatments can vary widely, and further dedicated studies would be necessary to understand vitamin D3's specific role in headache management. For now, combining it with other treatments was part of a broader strategy to achieve recovery.
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9
Atorvastatin aids migraine control
Does atorvastatin have augmentative effects with sodium valproate in prevention of migraine with aura attacks? A triple-blind controlled clinical trial.
We explored the relationship between vitamin D3 levels and migraine management in a study involving 68 patients suffering from migraine with aura. Before treatment, participants underwent vitamin D3 level evaluations, and those found to be deficient received vitamin D supplementation. However, while we investigated the effectiveness of adding atorvastatin to sodium valproate for better control of migraine symptoms, the specific effects of vitamin D3 alone on headache were not isolated in this study.
The results indicated that incorporating atorvastatin significantly reduced the severity of pain and the number of attacks. Participants in the atorvastatin group also reported higher satisfaction with their treatment compared to those receiving a placebo. Nonetheless, since the detailed effects of vitamin D3 on headaches were not independently assessed, we can’t conclude anything definitive about its role in headache management from this study alone.
Overall, while statins like atorvastatin show promise in treating migraine, our study did not directly evaluate the benefits of vitamin D3 on headache relief. Further research is needed to clarify vitamin D3's impact in this area.
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9
Vitamin D enhances migraine prevention
Efficacy of Topiramate Alone and Topiramate Plus Vitamin D3 in the Prophylaxis of Pediatric Migraine: A Randomized Clinical Trial.
We conducted a study to compare the effectiveness of topiramate, a medication traditionally used for migraine prevention, along with vitamin D3 in children. In a controlled, randomized clinical trial, we looked at children aged 5 to 15 who were experiencing migraines. Half of the participants received topiramate alone, while the other half received topiramate combined with vitamin D3 over two months.
Our findings revealed that both treatments significantly reduced the frequency and severity of migraines. However, the children who took topiramate along with vitamin D3 enjoyed even greater benefits. Specifically, those receiving the combination treatment reported fewer headache days and a lower level of disability due to migraines compared to those on topiramate alone. This combination treatment also led to a higher percentage of participants feeling a good response to their migraine management.
While some mild side effects were noted, they were temporary and similar across both treatment groups, suggesting that this combination is generally safe. Overall, we see that supplementing topiramate with vitamin D3 appears to be a promising strategy for protecting children against migraines.
Okay, my favourite brand! It already includes Vitamins D3 and K2 together. The headache has stopped, the drowsiness has gone, and my skin and nails are gradually improving. I appreciate the composition, free from artificial additives, soy, and flavourings. Excellent effect without side effects.
Read More
9
Headache disappearance
It can safely be called a vitamin for women's health. The balanced composition with vitamin K enhances the absorption of vitamin D. After completing the course, fatigue, lethargy, and headaches vanished. It also fortifies the immune system.
Read More
9
Headaches gone
My mother and I took it daily for almost a month. Both of our headaches disappeared, our blood pressure normalised, and our nerves calmed. I recommend this brand to everyone; it genuinely helps.
Read More
0
Strong for me
2 people found this helpful
Not for me. My dentist recommended this, but I found it too potent after trying it for a few weeks. It caused headaches, slight blurry vision in the mornings, and tiredness. I’m now taking it every other day, but I wish I could lower the dose, as it's in capsule form.
Read More
9
No headaches
I had increased levels in my blood when tested. There have been no headaches unlike other vitamin D supplements I tried in the past.
A headache is a common condition characterized by pain or discomfort in the head, scalp, or neck. It can vary in intensity, frequency, and duration, and is often classified into two primary categories: primary and secondary headaches. Primary headaches, such as tension-type headaches, migraines, and cluster headaches, are not caused by other medical conditions. Instead, they are conditions in themselves, often resulting from factors like stress, hormonal changes, or environmental triggers. Secondary headaches, on the other hand, are symptoms of an underlying issue, such as an infection, injury, or other medical conditions.
The experience of a headache can differ widely among individuals. Depending on the type, headaches can be throbbing or constant and may be accompanied by other symptoms like nausea, sensitivity to light, or aura effects before the headache strikes. Effective management strategies vary by headache type and may include over-the-counter pain relievers, lifestyle changes, and in some cases, prescription medications. Understanding the specific triggers and patterns related to your headaches can be crucial for prevention and treatment, so maintaining a headache diary may be beneficial for those experiencing frequent or severe episodes.
Vitamin D3 K2 is a supplement that combines two vital nutrients: vitamin D3 (cholecalciferol) and vitamin K2 (menaquinone). Vitamin D3 is crucial for maintaining healthy bones and immune function, as it helps the body absorb calcium, which is essential for bone strength. It can be obtained through sunlight exposure, certain foods, and supplements. On the other hand, vitamin K2 plays a significant role in directing calcium to the bones and teeth while preventing it from depositing in the arteries and soft tissues, thus promoting cardiovascular health and overall well-being.
The synergy between vitamin D3 and K2 is particularly important because they work together to ensure that calcium is utilized effectively in the body. While vitamin D3 boosts calcium absorption, vitamin K2 ensures that this calcium is deposited properly in the bones rather than accumulating in the arteries. This combination is believed to support bone density, cardiovascular health, and overall vitality. Many health professionals recommend considering a D3 and K2 supplement, especially for individuals who may be at risk of deficiency or those who live in areas with limited sunlight exposure. Always consult a healthcare provider before starting any new supplement regimen.
Based on user reviews, the time it typically takes to see results from this supplement for headache relief varies among individuals, but several users have reported noticeable improvements within a month of consistent use. For instance, one user mentioned that after taking the supplement daily for nearly a month, both she and her mother experienced a complete cessation of their headaches, alongside other health benefits like normalized blood pressure and reduced stress levels Read Review. Another reviewer indicated that while initially the headaches were severe, they became less frequent and less intense over time with continued use Read Review.
Furthermore, several users indicated a gradual decrease in headache frequency after incorporating the supplement into their routines, with some seeing improvements as early as a few weeks into their regimen Read Review. However, it’s essential to note that individual responses may vary, and the collective experience suggests that consistency in taking the supplement is key to unlocking its potential benefits for headache relief.
Vitamin D3 supplementation has shown promising results in certain studies related to headache management, particularly for migraines. For instance, a clinical trial with children experiencing migraines found that those receiving vitamin D3 alongside topiramate experienced a significant reduction in headache frequency and disability compared to the placebo group, with 76% reporting positive responses to the treatment [1]. Another study involving adults indicated that vitamin D3 could lead to fewer headache days and less severe pain among those with episodic migraines, suggesting its potential effectiveness in managing headache symptoms [8]. However, while these findings are encouraging, further research is necessary to establish definitive guidelines on the supplementation's role in headache relief and identify the optimal dosages.
Additionally, other studies have pointed to the correlation between low vitamin D levels and headache incidence, showing that individuals with migraines often present with deficiencies [6]. However, it’s important to note that not all research connects vitamin D3 supplementation directly to headache reduction. Some studies found no conclusive evidence supporting its efficacy against headaches, indicating that while vitamin D3 may contribute positively in some situations, it does not universally alleviate headache symptoms [15]. In summary, while there is scientific support for the potential benefits of vitamin D3 in managing migraines and headache severity, further investigation is warranted to solidify its effectiveness in broader populations.
Users have reported a range of symptom improvements, particularly in relation to headaches and overall well-being. Many individuals noted a cessation of headaches after consistent use of the supplement. For instance, one user stated that both she and her mother experienced a complete disappearance of headaches after nearly a month of daily use Read Review. Similarly, another reviewer mentioned a significant reduction in headache severity and frequency, particularly after suffering from severe headaches and nosebleeds at the start of their regimen Read Review.
Additionally, some users have highlighted improvements in other symptoms, such as fatigue and lethargy, which they reported fading away after taking the supplement Read Review. Reviews also noted enhancements in skin health and hair condition, indicating that the benefits extend beyond headache relief Read Review. While these anecdotal accounts are promising, it's important to remember that individual experiences may vary, and consistent supplementation seems to play a crucial role in achieving these positive outcomes.
Users have reported positive experiences when combining this supplement with other nutrients, particularly for headache relief. A recurring theme in the reviews highlights the efficacy of the supplement in alleviating headaches, often in conjunction with vitamins like D3 and K2. For example, one user noted a cessation of headaches and improvement in fatigue and skin health after regular use of this combination supplement Read Review. Additionally, another reviewer emphasized that the balanced formulation, particularly the vitamin K that aids in the absorption of vitamin D, contributed to vanishing fatigue and headaches Read Review.
Others also corroborated the benefit of this supplement for headaches, with one user stating that both she and her mother experienced complete relief after near-monthly use Read Review. Additionally, another review highlighted a marked reduction in headache severity after integrating the supplement into their regimen for two years Read Review. These anecdotal accounts suggest that users have found value in not only the individual supplement but also in how it complements other health-promoting nutrients, enhancing overall well-being and specifically targeting headache issues.
Based on user reviews, there appears to be a consensus that Vitamin D3 K2 can effectively alleviate headaches. Many users reported improvements after incorporating these vitamins into their daily routine. For instance, one user noted that after taking the supplement, headaches disappeared along with feelings of fatigue and lethargy, highlighting the enhanced absorption provided by the combination of Vitamin K with Vitamin D Read Review. Another user shared a similar experience, stating that both they and their mother experienced a noticeable cessation of headaches and normalization of blood pressure Read Review.
Additionally, several users mentioned a significant reduction in headache frequency and severity over time. One user specifically reported that their headaches became rare and mild after long-term use, attributing this improvement to the Vitamin D3 K2 they took for other health issues Read Review. Another noted a decrease in headaches after only a few months of use alongside other health benefits Read Review. While individual experiences vary, these testimonials suggest that a thoughtful regimen of Vitamin D3 K2 may promote significant relief from headaches.
9
Headaches gone
My mother and I took it daily for almost a month. Both of our headaches disappeared, our blood pressure normalised, and our nerves calmed. I recommend this brand to everyone; it genuinely helps.
7.5
Headache reduction
I have been taking it for the second year in spring and autumn. The first time I used it was for severe headaches and frequent nosebleeds. Now, the headache occurs very rarely and is not so severe. I haven't had any nosebleeds since.
7.5
Fewer headaches
Since the beginning of the year, I have been taking these vitamins, and my hair's condition, facial rash, and overall health have improved! The headaches have decreased! This complex was recommended by my cosmetologist due to thyroid gland issues.
9
Headache disappearance
It can safely be called a vitamin for women's health. The balanced composition with vitamin K enhances the absorption of vitamin D. After completing the course, fatigue, lethargy, and headaches vanished. It also fortifies the immune system.
9
Headache relief
Okay, my favourite brand! It already includes Vitamins D3 and K2 together. The headache has stopped, the drowsiness has gone, and my skin and nails are gradually improving. I appreciate the composition, free from artificial additives, soy, and flavourings. Excellent effect without side effects.
9
Pediatric migraine treatment effectiveness
The Impact of Vitamin D Supplementation to Topiramate Therapy on Pediatric Migraine Prophylaxis.
We aimed to explore the effects of vitamin D3 supplementation on headaches in children undergoing treatment with topiramate for migraines. In a carefully designed double-blind clinical trial, we involved children aged 5 to 14 years who were experiencing migraines. Participants were randomly divided into two groups: one received topiramate with vitamin D3 supplements, while the other received topiramate along with a placebo.
Over four months, we noted significant enhancements in the group taking vitamin D3. Specifically, this group showed a greater reduction in the frequency of headache attacks and overall migraine disability compared to the placebo group. We observed that 76% of children in the vitamin D3 group reported good responses to the treatment, compared to only 54% in the placebo group.
Importantly, while both groups experienced side effects, those in the vitamin D3 group reported fewer issues. Thus, we found vitamin D3 supplementation to be a well-tolerated and effective addition to topiramate therapy for managing pediatric migraines.
9
Vitamin D3 aids migraine relief
Vitamin D3 might improve headache characteristics and protect against inflammation in migraine: a randomized clinical trial.
We conducted a rigorous study to explore how vitamin D3 supplementation might influence headaches in people suffering from migraines. By utilizing a well-structured, placebo-controlled, double-blind design, we included 80 participants with episodic migraines, assigning them either a daily dose of vitamin D3 or a placebo for 12 weeks.
After the study, we observed significant improvements in those receiving vitamin D3. Participants reported fewer headache days each month, shorter headache durations, and less severe pain overall. They also used fewer pain relievers compared to those on placebo, showcasing the potential benefit of vitamin D3 in managing migraine symptoms.
Our findings suggest that vitamin D3 not only aids in reducing headache frequency but may also play a role in addressing inflammation, as evidenced by reduced levels of certain inflammatory markers in the blood. This highlights its possible therapeutic value for migraine sufferers, indicating that a daily dose could make a meaningful difference in their lives.
8
Vitamin D may alleviate migraines
The effects of vitamin D supplementation on interictal serum levels of calcitonin gene-related peptide (CGRP) in episodic migraine patients: post hoc analysis of a randomized double-blind placebo-controlled trial.
We conducted a thorough investigation into how vitamin D3 might influence headache symptoms in people suffering from episodic migraines. By setting up a structured 16-week randomized, double-blind, placebo-controlled trial involving 80 participants, we aimed to gain a clearer understanding of this relationship.
Participants were divided into two groups: one received a daily dose of 2000 IU of vitamin D, while the other group received a placebo. Throughout this period, we encouraged patients to keep headache diaries and utilized a migraine disability assessment questionnaire to track their progress. We also measured interictal serum levels of calcitonin gene-related peptide (CGRP), a key player in migraine pain, using an ELISA method.
Our findings indicated that vitamin D supplementation may improve migraine characteristics and reduce disability, especially for those with migraine with aura. This possible improvement might be linked to lower CGRP levels, suggesting an intriguing connection between vitamin D and migraine management.
However, while our results are promising, further research is essential to verify these outcomes and fully understand the mechanisms at play. We believe that this study opens new avenues for exploring the benefits of vitamin D in migraine treatment.
4
Vitamin D3 shows limited migraine impact
The relationship between serum levels of vitamin D and migraine.
We explored the relationship between serum levels of vitamin D3 and migraines in a study involving 76 migraine patients aged 10 to 61. Our aim was to see if there was any link between vitamin D levels and the frequency or severity of headaches.
Through our analysis, we found a weak positive connection between higher levels of vitamin D3 and the results recorded in headache diaries. This suggests that, for some individuals, increased vitamin D levels might be associated with more frequent headache occurrences. However, when we looked for a relationship between vitamin D levels and the severity of migraines, we found no significant correlation.
Ultimately, while there appears to be some connection between vitamin D3 and headache frequency, it seems not to impact the intensity of migraines. This means that simply boosting vitamin D levels may not be a reliable strategy for reducing the severity of migraine attacks.
References
Kotb Elmala M, Suliman HA, Al-Shokary AH, Ibrahim AO, Kamal NM, et al. The Impact of Vitamin D Supplementation to Topiramate Therapy on Pediatric Migraine Prophylaxis. J Child Neurol. 2022;37:833. 10.1177/08830738221092882
Mursi AM, Mirghani HO, Elbeialy AA. A Case Report of Post COVID19 Giant Cell Arteritis and Polymyalgia Rheumatica With Visual Loss. Clin Med Insights Case Rep. 2022;15:11795476221088472. 10.1177/11795476221088472
Ganji R, Majdinasab N, Hesam S, Rostami N, Sayyah M, et al. Does atorvastatin have augmentative effects with sodium valproate in prevention of migraine with aura attacks? A triple-blind controlled clinical trial. J Pharm Health Care Sci. 2021;7:12. 10.1186/s40780-021-00198-8
Ghorbani Z, Rafiee P, Haghighi S, Razeghi Jahromi S, Djalali M, et al. The effects of vitamin D3 supplementation on TGF-β and IL-17 serum levels in migraineurs: post hoc analysis of a randomized clinical trial. J Pharm Health Care Sci. 2021;7:9. 10.1186/s40780-021-00192-0
Fallah R, Sarraf Yazd S, Sohrevardi SM. Efficacy of Topiramate Alone and Topiramate Plus Vitamin D3 in the Prophylaxis of Pediatric Migraine: A Randomized Clinical Trial. Iran J Child Neurol. 2020;14:77.
Ghorbani Z, Rafiee P, Fotouhi A, Haghighi S, Rasekh Magham R, et al. The effects of vitamin D supplementation on interictal serum levels of calcitonin gene-related peptide (CGRP) in episodic migraine patients: post hoc analysis of a randomized double-blind placebo-controlled trial. J Headache Pain. 2020;21:22. 10.1186/s10194-020-01090-w
Nowaczewska M, Wiciński M, Osiński S, Kaźmierczak H. The Role of Vitamin D in Primary Headache-from Potential Mechanism to Treatment. Nutrients. 2020;12. 10.3390/nu12010243
Ghorbani Z, Togha M, Rafiee P, Ahmadi ZS, Rasekh Magham R, et al. Vitamin D3 might improve headache characteristics and protect against inflammation in migraine: a randomized clinical trial. Neurol Sci. 2020;41:1183. 10.1007/s10072-019-04220-8
Ghorbani Z, Togha M, Rafiee P, Ahmadi ZS, Rasekh Magham R, et al. Vitamin D in migraine headache: a comprehensive review on literature. Neurol Sci. 2019;40:2459. 10.1007/s10072-019-04021-z
Gazerani P, Fuglsang R, Pedersen JG, Sørensen J, Kjeldsen JL, et al. A randomized, double-blinded, placebo-controlled, parallel trial of vitamin D supplementation in adult patients with migraine. Curr Med Res Opin. 2019;35:715. 10.1080/03007995.2018.1519503
Donmez A, Orun E, Sonmez FM. Vitamin D status in children with headache: A case-control study. Clin Nutr ESPEN. 2018;23:222. 10.1016/j.clnesp.2017.09.010
Prakash S, Rathore C, Makwana P, Dave A, Joshi H, et al. Vitamin D Deficiency in Patients With Chronic Tension-Type Headache: A Case-Control Study. Headache. 2017;57:1096. 10.1111/head.13096
Buettner C, Nir RR, Bertisch SM, Bernstein C, Schain A, et al. Simvastatin and vitamin D for migraine prevention: A randomized, controlled trial. Ann Neurol. 2015;78:970. 10.1002/ana.24534
Laursen JC, Cairns BE, Kumar U, Somvanshi RK, Dong XD, et al. Nitric oxide release from trigeminal satellite glial cells is attenuated by glial modulators and glutamate. Int J Physiol Pathophysiol Pharmacol. 2013;5:228.
Mottaghi T, Khorvash F, Askari G, Maracy MR, Ghiasvand R, et al. The relationship between serum levels of vitamin D and migraine. J Res Med Sci. 2013;18:S66.