Overview
SCIENTIFIC SCORE
Possibly Effective
Based on 13 Researches
7.3
USERS' SCORE
Good
Based on 3 Reviews
8
Supplement Facts
Serving Size: 1 Capsule
Amount Per Serving
%DV
Vitamin D3 (as cholecalciferol)
125 mcg
625%
Vitamin K activity from:Vitamin K1 (as phytonadione)Vitamin K2 (as menaquinone-4)Vitamin K2 (as trans menaquinone-7)
2,100 mcg1,000 mcg1,000 mcg100 mcg
1,750%
Iodine [from Sea-Iodine™ Complex Blend (organic kelp and bladderwrack extracts, potassium iodide)]
1,000 mcg
667%
Top Medical Research Studies
9
We examined the impact of calcitriol, the active form of vitamin D, on heart attack recovery using a mouse model of myocardial infarction (MI). In our study, we treated mice that had suffered a MI with calcitriol and observed promising results.
Our findings revealed that calcitriol helped reverse negative effects on heart function and reduced cardiac remodeling after a heart attack. It also targeted the inflammatory response typically associated with MI, improving the survival of heart muscle cells and promoting their regeneration.
We discovered that calcitriol works by enhancing the activity of the Vitamin D receptor (VDR). This process not only interferes with inflammatory signals but also leads to positive changes at the genetic level, further supporting heart health after an MI. Overall, our study provides strong evidence of calcitriol's cardioprotective properties, making it a potential treatment avenue for better outcomes following a heart attack.
Our findings revealed that calcitriol helped reverse negative effects on heart function and reduced cardiac remodeling after a heart attack. It also targeted the inflammatory response typically associated with MI, improving the survival of heart muscle cells and promoting their regeneration.
We discovered that calcitriol works by enhancing the activity of the Vitamin D receptor (VDR). This process not only interferes with inflammatory signals but also leads to positive changes at the genetic level, further supporting heart health after an MI. Overall, our study provides strong evidence of calcitriol's cardioprotective properties, making it a potential treatment avenue for better outcomes following a heart attack.
9
We explored the impact of 1,25-dihydroxyvitamin D3 (VD3) on heart health, particularly after an acute myocardial infarction (AMI). To investigate this, we used male C57/BL6J mice and conducted a series of experiments, comparing those treated with VD3 to control groups.
Our findings revealed that VD3 treated mice showed significant improvement in heart function following AMI. This treatment not only enhanced cardiac function parameters but also reduced inflammation and the extent of myocardial damage. There was a notable decline in inflammatory markers and a decrease in cell apoptosis, indicated by a rise in protective proteins and a fall in those that lead to cell death.
In our in vitro studies with cardiomyocytes, we observed that VD3 boosted autophagy markers, enhancing the body’s ability to manage damaged cells. It seemed to activate key pathways involved in cell survival and repair, specifically the PI3K/AKT/mTOR pathway. However, when we inhibited this pathway with 3-methyladenine, the benefits of VD3 were reversed, indicating a direct link between autophagy promotion and the protective effects of VD3.
In summary, our research indicates that VD3 can be a valuable ally in the fight against heart damage and inflammation after a heart attack, primarily by supporting cellular repair processes.
Our findings revealed that VD3 treated mice showed significant improvement in heart function following AMI. This treatment not only enhanced cardiac function parameters but also reduced inflammation and the extent of myocardial damage. There was a notable decline in inflammatory markers and a decrease in cell apoptosis, indicated by a rise in protective proteins and a fall in those that lead to cell death.
In our in vitro studies with cardiomyocytes, we observed that VD3 boosted autophagy markers, enhancing the body’s ability to manage damaged cells. It seemed to activate key pathways involved in cell survival and repair, specifically the PI3K/AKT/mTOR pathway. However, when we inhibited this pathway with 3-methyladenine, the benefits of VD3 were reversed, indicating a direct link between autophagy promotion and the protective effects of VD3.
In summary, our research indicates that VD3 can be a valuable ally in the fight against heart damage and inflammation after a heart attack, primarily by supporting cellular repair processes.
8
We explored the impact of vitamin D levels on heart attack severity by examining 77 patients who experienced ST-elevation myocardial infarction (STEMI). A key focus was to understand how vitamin D deficiency might relate to the amount of thrombus, or blood clots, present in coronary arteries.
The findings revealed that a striking 79.22% of patients had vitamin D levels below what is considered adequate (less than 20 ng/mL). Notably, those with mild thrombus loads had higher vitamin D levels compared to those classified with severe thrombus loads, indicating a clear connection.
Furthermore, we discovered a negative correlation between vitamin D levels and the severity of thrombus. The lower the vitamin D levels, the higher the thrombus burden and the post-procedural TIMI frame count—essentially metrics that show how blood flows in the heart after treatment. This highlights that maintaining adequate vitamin D might be crucial for individuals at risk of severe heart complications.
The findings revealed that a striking 79.22% of patients had vitamin D levels below what is considered adequate (less than 20 ng/mL). Notably, those with mild thrombus loads had higher vitamin D levels compared to those classified with severe thrombus loads, indicating a clear connection.
Furthermore, we discovered a negative correlation between vitamin D levels and the severity of thrombus. The lower the vitamin D levels, the higher the thrombus burden and the post-procedural TIMI frame count—essentially metrics that show how blood flows in the heart after treatment. This highlights that maintaining adequate vitamin D might be crucial for individuals at risk of severe heart complications.
Most Useful Reviews
7.5
Heart no longer pains
I am highly satisfied with the vitamin D product in capsule form. Its combination with vitamin K effectively delivers benefits where needed most. Over nine months, my heart pain subsided; I previously used Panangin. The added iodine is relevant for my region. Overall, this product suits me well, and delivery was prompt.
9
Boosted energy levels
Taking Vitamin D and K has been remarkable! This combination significantly improved my bone health and immunity. It promotes calcium absorption and supports heart health. Since including it in my routine, I feel more energetic and balanced. I highly recommend it as a quality supplement for anyone focused on health!
2
Unpleasant side effects
I experienced discomfort in my heart after taking these vitamins. Unpleasant sensations arose, perhaps due to a high dose or the incompatibility of vitamin K with my system.
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 13 Researches
7.3
- All Researches
9.5
We conducted a detailed study to uncover how vitamin D3, combined with exercise, affects recovery from heart attacks. Our research involved fifty-six male rats, some of which experienced a simulated heart attack, while others served as a control group.
The rats were then divided into several groups, receiving different treatments over eight weeks. We specifically looked at how vitamin D3 and aerobic-resistance training together impacted cardiac health, focusing on the important TGF-β1/Smad signaling pathway known to contribute to heart damage.
Our findings were quite revealing. We noticed that the combinations of vitamin D3 and exercise training significantly improved heart function. Specifically, those receiving both treatments showed higher heart ejection fractions and lower levels of TGF-β1 and collagen proteins, indicating less cardiac fibrosis. In contrast, the groups that only received one treatment did not show the same level of improvement.
This suggests that while vitamin D3 on its own was not studied in isolation, its combination with exercise led to better outcomes in heart attack recovery. Overall, these results indicate a promising role for vitamin D3 alongside exercise in supporting heart health after a heart attack.
The rats were then divided into several groups, receiving different treatments over eight weeks. We specifically looked at how vitamin D3 and aerobic-resistance training together impacted cardiac health, focusing on the important TGF-β1/Smad signaling pathway known to contribute to heart damage.
Our findings were quite revealing. We noticed that the combinations of vitamin D3 and exercise training significantly improved heart function. Specifically, those receiving both treatments showed higher heart ejection fractions and lower levels of TGF-β1 and collagen proteins, indicating less cardiac fibrosis. In contrast, the groups that only received one treatment did not show the same level of improvement.
This suggests that while vitamin D3 on its own was not studied in isolation, its combination with exercise led to better outcomes in heart attack recovery. Overall, these results indicate a promising role for vitamin D3 alongside exercise in supporting heart health after a heart attack.
9
We examined the impact of calcitriol, the active form of vitamin D, on heart attack recovery using a mouse model of myocardial infarction (MI). In our study, we treated mice that had suffered a MI with calcitriol and observed promising results.
Our findings revealed that calcitriol helped reverse negative effects on heart function and reduced cardiac remodeling after a heart attack. It also targeted the inflammatory response typically associated with MI, improving the survival of heart muscle cells and promoting their regeneration.
We discovered that calcitriol works by enhancing the activity of the Vitamin D receptor (VDR). This process not only interferes with inflammatory signals but also leads to positive changes at the genetic level, further supporting heart health after an MI. Overall, our study provides strong evidence of calcitriol's cardioprotective properties, making it a potential treatment avenue for better outcomes following a heart attack.
Our findings revealed that calcitriol helped reverse negative effects on heart function and reduced cardiac remodeling after a heart attack. It also targeted the inflammatory response typically associated with MI, improving the survival of heart muscle cells and promoting their regeneration.
We discovered that calcitriol works by enhancing the activity of the Vitamin D receptor (VDR). This process not only interferes with inflammatory signals but also leads to positive changes at the genetic level, further supporting heart health after an MI. Overall, our study provides strong evidence of calcitriol's cardioprotective properties, making it a potential treatment avenue for better outcomes following a heart attack.
9
We explored the effects of vitamin D3 on heart injury caused by ischemia/reperfusion (I/R), a common scenario during heart attacks. Using a laboratory model that mimicked this condition, we discovered that I/R treatment significantly harmed heart cells, leading to cell death and increased oxidative stress.
We observed that I/R conditions prompted an increase in mitochondrial fission and mitophagy—mechanisms that can worsen heart injury. However, when we introduced vitamin D3, it appeared to counteract these detrimental effects. Specifically, vitamin D3 decreased cell death and reduced harmful mitochondrial changes, suggesting a protective role for this vitamin.
In live mice undergoing I/R, we confirmed that vitamin D3 treatment effectively reduced not only apoptosis (cell death) but also the adverse changes in mitochondrial function and structure. Overall, our findings indicate that vitamin D3 could be an important ally in safeguarding the heart during a heart attack by maintaining the integrity of mitochondrial function.
We observed that I/R conditions prompted an increase in mitochondrial fission and mitophagy—mechanisms that can worsen heart injury. However, when we introduced vitamin D3, it appeared to counteract these detrimental effects. Specifically, vitamin D3 decreased cell death and reduced harmful mitochondrial changes, suggesting a protective role for this vitamin.
In live mice undergoing I/R, we confirmed that vitamin D3 treatment effectively reduced not only apoptosis (cell death) but also the adverse changes in mitochondrial function and structure. Overall, our findings indicate that vitamin D3 could be an important ally in safeguarding the heart during a heart attack by maintaining the integrity of mitochondrial function.
9
We explored the impact of 1,25-dihydroxyvitamin D3 (VD3) on heart health, particularly after an acute myocardial infarction (AMI). To investigate this, we used male C57/BL6J mice and conducted a series of experiments, comparing those treated with VD3 to control groups.
Our findings revealed that VD3 treated mice showed significant improvement in heart function following AMI. This treatment not only enhanced cardiac function parameters but also reduced inflammation and the extent of myocardial damage. There was a notable decline in inflammatory markers and a decrease in cell apoptosis, indicated by a rise in protective proteins and a fall in those that lead to cell death.
In our in vitro studies with cardiomyocytes, we observed that VD3 boosted autophagy markers, enhancing the body’s ability to manage damaged cells. It seemed to activate key pathways involved in cell survival and repair, specifically the PI3K/AKT/mTOR pathway. However, when we inhibited this pathway with 3-methyladenine, the benefits of VD3 were reversed, indicating a direct link between autophagy promotion and the protective effects of VD3.
In summary, our research indicates that VD3 can be a valuable ally in the fight against heart damage and inflammation after a heart attack, primarily by supporting cellular repair processes.
Our findings revealed that VD3 treated mice showed significant improvement in heart function following AMI. This treatment not only enhanced cardiac function parameters but also reduced inflammation and the extent of myocardial damage. There was a notable decline in inflammatory markers and a decrease in cell apoptosis, indicated by a rise in protective proteins and a fall in those that lead to cell death.
In our in vitro studies with cardiomyocytes, we observed that VD3 boosted autophagy markers, enhancing the body’s ability to manage damaged cells. It seemed to activate key pathways involved in cell survival and repair, specifically the PI3K/AKT/mTOR pathway. However, when we inhibited this pathway with 3-methyladenine, the benefits of VD3 were reversed, indicating a direct link between autophagy promotion and the protective effects of VD3.
In summary, our research indicates that VD3 can be a valuable ally in the fight against heart damage and inflammation after a heart attack, primarily by supporting cellular repair processes.
8
We examined the effects of marine n-3 fatty acids, alongside vitamin D3, on cardiovascular disease events, particularly heart attacks. In the VITAL trial, which involved nearly 26,000 healthy older adults, participants were given either a supplement of n-3 fatty acids or a placebo to see if it would lower the risk of significant heart events.
The findings indicated a modest, though not significant, benefit of n-3 fatty acid supplementation regarding heart attacks. Specifically, the study revealed that while there was a reduction in non-fatal heart attacks, there was no clear impact on stroke outcomes. Interestingly, those with lower fish consumption at the start showed a stronger benefit from the n-3 fatty acids compared to their counterparts who consumed more fish.
However, it's important to note that the evaluation did not find any substantial isolated effect of vitamin D3 on heart attacks. Overall, our study suggests that while n-3 fatty acids might have some positive effects, particularly in certain groups, the same cannot be confidently stated for vitamin D3 alone in preventing heart attacks.
The findings indicated a modest, though not significant, benefit of n-3 fatty acid supplementation regarding heart attacks. Specifically, the study revealed that while there was a reduction in non-fatal heart attacks, there was no clear impact on stroke outcomes. Interestingly, those with lower fish consumption at the start showed a stronger benefit from the n-3 fatty acids compared to their counterparts who consumed more fish.
However, it's important to note that the evaluation did not find any substantial isolated effect of vitamin D3 on heart attacks. Overall, our study suggests that while n-3 fatty acids might have some positive effects, particularly in certain groups, the same cannot be confidently stated for vitamin D3 alone in preventing heart attacks.
User Reviews
USERS' SCORE
Good
Based on 3 Reviews
8
- All Reviews
- Positive Reviews
- Negative Reviews
7.5
Heart no longer pains
I am highly satisfied with the vitamin D product in capsule form. Its combination with vitamin K effectively delivers benefits where needed most. Over nine months, my heart pain subsided; I previously used Panangin. The added iodine is relevant for my region. Overall, this product suits me well, and delivery was prompt.
9
Boosted energy levels
Taking Vitamin D and K has been remarkable! This combination significantly improved my bone health and immunity. It promotes calcium absorption and supports heart health. Since including it in my routine, I feel more energetic and balanced. I highly recommend it as a quality supplement for anyone focused on health!
2
Unpleasant side effects
I experienced discomfort in my heart after taking these vitamins. Unpleasant sensations arose, perhaps due to a high dose or the incompatibility of vitamin K with my system.
Frequently Asked Questions
7.5
Heart no longer pains
I am highly satisfied with the vitamin D product in capsule form. Its combination with vitamin K effectively delivers benefits where needed most. Over nine months, my heart pain subsided; I previously used Panangin. The added iodine is relevant for my region. Overall, this product suits me well, and delivery was prompt.
9
Boosted energy levels
Taking Vitamin D and K has been remarkable! This combination significantly improved my bone health and immunity. It promotes calcium absorption and supports heart health. Since including it in my routine, I feel more energetic and balanced. I highly recommend it as a quality supplement for anyone focused on health!
2
Unpleasant side effects
I experienced discomfort in my heart after taking these vitamins. Unpleasant sensations arose, perhaps due to a high dose or the incompatibility of vitamin K with my system.
4
We conducted a comprehensive study to explore whether vitamin D3 supplementation influences the occurrence of heart attacks among older adults. This research was carried out through a randomized, double-blind, placebo-controlled trial involving over 21,000 participants aged between 60 and 84 years in Australia between 2014 and 2020.
Participants took either a monthly dose of 60,000 IU of vitamin D3 or a placebo for up to five years. When we looked at the main focus of our analysis—major cardiovascular events like heart attacks—we found that while vitamin D supplementation might lead to a slight reduction in these events, the absolute risk difference was small. Ultimately, the confidence intervals surrounding our findings suggested that there could be no effect at all.
Our study's results imply that while vitamin D3 might have potential benefits, its impact on heart attack prevention specifically is unclear. These insights could encourage further investigation into vitamin D supplements, especially for those currently on medications for heart disease.
Participants took either a monthly dose of 60,000 IU of vitamin D3 or a placebo for up to five years. When we looked at the main focus of our analysis—major cardiovascular events like heart attacks—we found that while vitamin D supplementation might lead to a slight reduction in these events, the absolute risk difference was small. Ultimately, the confidence intervals surrounding our findings suggested that there could be no effect at all.
Our study's results imply that while vitamin D3 might have potential benefits, its impact on heart attack prevention specifically is unclear. These insights could encourage further investigation into vitamin D supplements, especially for those currently on medications for heart disease.
8
We examined the effects of marine n-3 fatty acids, alongside vitamin D3, on cardiovascular disease events, particularly heart attacks. In the VITAL trial, which involved nearly 26,000 healthy older adults, participants were given either a supplement of n-3 fatty acids or a placebo to see if it would lower the risk of significant heart events.
The findings indicated a modest, though not significant, benefit of n-3 fatty acid supplementation regarding heart attacks. Specifically, the study revealed that while there was a reduction in non-fatal heart attacks, there was no clear impact on stroke outcomes. Interestingly, those with lower fish consumption at the start showed a stronger benefit from the n-3 fatty acids compared to their counterparts who consumed more fish.
However, it's important to note that the evaluation did not find any substantial isolated effect of vitamin D3 on heart attacks. Overall, our study suggests that while n-3 fatty acids might have some positive effects, particularly in certain groups, the same cannot be confidently stated for vitamin D3 alone in preventing heart attacks.
The findings indicated a modest, though not significant, benefit of n-3 fatty acid supplementation regarding heart attacks. Specifically, the study revealed that while there was a reduction in non-fatal heart attacks, there was no clear impact on stroke outcomes. Interestingly, those with lower fish consumption at the start showed a stronger benefit from the n-3 fatty acids compared to their counterparts who consumed more fish.
However, it's important to note that the evaluation did not find any substantial isolated effect of vitamin D3 on heart attacks. Overall, our study suggests that while n-3 fatty acids might have some positive effects, particularly in certain groups, the same cannot be confidently stated for vitamin D3 alone in preventing heart attacks.
9
We explored the impact of 1,25-dihydroxyvitamin D3 (VD3) on heart health, particularly after an acute myocardial infarction (AMI). To investigate this, we used male C57/BL6J mice and conducted a series of experiments, comparing those treated with VD3 to control groups.
Our findings revealed that VD3 treated mice showed significant improvement in heart function following AMI. This treatment not only enhanced cardiac function parameters but also reduced inflammation and the extent of myocardial damage. There was a notable decline in inflammatory markers and a decrease in cell apoptosis, indicated by a rise in protective proteins and a fall in those that lead to cell death.
In our in vitro studies with cardiomyocytes, we observed that VD3 boosted autophagy markers, enhancing the body’s ability to manage damaged cells. It seemed to activate key pathways involved in cell survival and repair, specifically the PI3K/AKT/mTOR pathway. However, when we inhibited this pathway with 3-methyladenine, the benefits of VD3 were reversed, indicating a direct link between autophagy promotion and the protective effects of VD3.
In summary, our research indicates that VD3 can be a valuable ally in the fight against heart damage and inflammation after a heart attack, primarily by supporting cellular repair processes.
Our findings revealed that VD3 treated mice showed significant improvement in heart function following AMI. This treatment not only enhanced cardiac function parameters but also reduced inflammation and the extent of myocardial damage. There was a notable decline in inflammatory markers and a decrease in cell apoptosis, indicated by a rise in protective proteins and a fall in those that lead to cell death.
In our in vitro studies with cardiomyocytes, we observed that VD3 boosted autophagy markers, enhancing the body’s ability to manage damaged cells. It seemed to activate key pathways involved in cell survival and repair, specifically the PI3K/AKT/mTOR pathway. However, when we inhibited this pathway with 3-methyladenine, the benefits of VD3 were reversed, indicating a direct link between autophagy promotion and the protective effects of VD3.
In summary, our research indicates that VD3 can be a valuable ally in the fight against heart damage and inflammation after a heart attack, primarily by supporting cellular repair processes.
8
We investigated the association between vitamin D3 levels and the development of collateral circulation in patients who experienced an acute ST-segment elevation myocardial infarction, also known as a heart attack. Our study involved 369 patients who were admitted within the first 12 hours of experiencing symptoms. We categorized them based on the degree of collateral circulation to the affected artery, separating them into groups with either poorly or well-developed collateral circulation.
Our findings revealed that higher levels of admission plasma 25-hydroxyvitamin D3 (25(OH)D3) were positively correlated with better collateralization grades. In contrast, markers of cardiac damage and stress, such as high-sensitivity C-reactive protein and troponin levels, showed a negative correlation with the quality of collateral circulation. Moreover, through multivariate analysis, we identified that admission levels of 25(OH)D3, alongside other biomarkers, were significant predictors of improved collateral circulation in acute heart attack patients.
In summary, it appears that vitamin D3 might play a role in improving the body’s natural response to heart attacks by enhancing collateral blood flow. While more research is needed to fully understand these dynamics, our study suggests that maintaining adequate vitamin D3 levels could be beneficial for heart health.
Our findings revealed that higher levels of admission plasma 25-hydroxyvitamin D3 (25(OH)D3) were positively correlated with better collateralization grades. In contrast, markers of cardiac damage and stress, such as high-sensitivity C-reactive protein and troponin levels, showed a negative correlation with the quality of collateral circulation. Moreover, through multivariate analysis, we identified that admission levels of 25(OH)D3, alongside other biomarkers, were significant predictors of improved collateral circulation in acute heart attack patients.
In summary, it appears that vitamin D3 might play a role in improving the body’s natural response to heart attacks by enhancing collateral blood flow. While more research is needed to fully understand these dynamics, our study suggests that maintaining adequate vitamin D3 levels could be beneficial for heart health.
References
- Olędzki S, Siennicka A, Maciejewska-Markiewicz D, Stachowska E, Jakubiak N, et al. Calcitriol Concentration in the Early Phase of Myocardial Infarction and Its Relation to Left Ventricular Ejection Fraction. Metabolites. 2024;14. doi:10.3390/metabo14120686
- Ogata S, Manson JE, Kang JH, Buring JE, Lee IM, et al. Marine n-3 Fatty Acids and Prevention of Cardiovascular Disease: A Novel Analysis of the VITAL Trial Using Win Ratio and Hierarchical Composite Outcomes. Nutrients. 2023;15. doi:10.3390/nu15194235
- Thompson B, Waterhouse M, English DR, McLeod DS, Armstrong BK, et al. Vitamin D supplementation and major cardiovascular events: D-Health randomised controlled trial. BMJ. 2023;381:e075230. doi:10.1136/bmj-2023-075230
- Bassuk SS, Manson JE. Marine omega-3 fatty acid supplementation and prevention of cardiovascular disease: update on the randomized trial evidence. Cardiovasc Res. 2023;119:1297. doi:10.1093/cvr/cvac172
- Uguz B, Oztas S, Zengin I, Topal D, Tiryakioglu SK, et al. Relationship between vitamin D deficiency and thrombus load in patients with ST-elevation myocardial infarction. Eur Rev Med Pharmacol Sci. 2022;26:7015. doi:10.26355/eurrev_202210_29885
- Yang S, Wang C, Ruan C, Chen M, Cao R, et al. Novel Insights into the Cardioprotective Effects of Calcitriol in Myocardial Infarction. Cells. 2022;11. doi:10.3390/cells11101676
- Şen Ö, Şen SB, Topuz AN, Topuz M. Vitamin D level predicts angiographic no-reflow phenomenon after percutaneous coronary intervention in patients with ST segment elevation myocardial infarction. Biomark Med. 2021;15:1357. doi:10.2217/bmm-2020-0689
- Mehdipoor M, Damirchi A, Razavi Tousi SMT, Babaei P. Concurrent vitamin D supplementation and exercise training improve cardiac fibrosis via TGF-β/Smad signaling in myocardial infarction model of rats. J Physiol Biochem. 2021;77:75. doi:10.1007/s13105-020-00778-6
- Lee TL, Lee MH, Chen YC, Lee YC, Lai TC, et al. Vitamin D Attenuates Ischemia/Reperfusion-Induced Cardiac Injury by Reducing Mitochondrial Fission and Mitophagy. Front Pharmacol. 2020;11:604700. doi:10.3389/fphar.2020.604700
- Wei YX, Dong SM, Wang YY, Zhang P, Sun MY, et al. Autophagy participates in the protection role of 1,25-dihydroxyvitamin D3 in acute myocardial infarction via PI3K/AKT/mTOR pathway. Cell Biol Int. 2021;45:394. doi:10.1002/cbin.11495
- Akkuş O, Topuz M, Öz F, Harbalıoğlu H, Koca H, et al. Impact of 25(OH)D3 on spontaneous reperfusion and SYNTAX score in patients with ST-elevation myocardial infarction. Turk Kardiyol Dern Ars. 2018;46:268. doi:10.5543/tkda.2018.49393
- Le TYL, Ogawa M, Kizana E, Gunton JE, Chong JJH. Vitamin D Improves Cardiac Function After Myocardial Infarction Through Modulation of Resident Cardiac Progenitor Cells. Heart Lung Circ. 2018;27:967. doi:10.1016/j.hlc.2018.01.006
- Şen Ö, Topuz M, Acele A, Akkuş O, Baykan AO, et al. The influence of plasma 25-(OH) vitamin D levels in acute ST elevation myocardial infarction. Cardiol J. 2017;24:677. doi:10.5603/CJ.a2017.0066
