Overview

SCIENTIFIC SCORE
Possibly Effective
Based on 3 Researches
7
USERS' SCORE
Good
Based on 12 Reviews
8.2
Supplement Facts
Serving Size: 1 Capsule
Amount Per Serving
%DV
Vitamin D3 (as cholecalciferol)
125 mcg
625%
Vitamin K activity from:Vitamin K1 (as phytonadione)Vitamin K2 (as menaquinone-4)Vitamin K2 (as trans menaquinone-7)
2,100 mcg1,000 mcg1,000 mcg100 mcg
1,750%
Iodine [from Sea-Iodine™ Complex Blend (organic kelp and bladderwrack extracts, potassium iodide)]
1,000 mcg
667%

Top Medical Research Studies

We set out to evaluate what effect vitamin D3 supplementation might have on patients suffering from mild obstructive sleep apnea syndrome (OSAS). In this study, 19 adult men who were diagnosed with mild OSAS and had low vitamin D levels participated over an 8-week period. Each week, they took a sizable dose of 50,000 IU of vitamin D3 while undergoing various health assessments. We measured important factors like blood glucose, lipid profiles, and inflammation markers, along with repeated sleep monitoring through polysomnography.

By the end of the study, we observed a significant increase in participants' vitamin D levels, which jumped from an average of 19.5 to 41.8 ng/mL—an indication that the supplementation was effective. Along with this rise in vitamin D, we also noted improvements in fasting blood glucose and total cholesterol levels, as well as a decrease in key inflammation markers. Most encouragingly, the frequency of obstructive apneas and other related sleep disturbances significantly decreased.

Based on these findings, it seems that vitamin D supplementation can play a beneficial role in improving the prognosis for those with mild OSAS. It's exciting to consider how something as simple as a vitamin could lead to better sleep health for individuals struggling with sleep apnea.
Read More
4
Vitamin D3 enhances metabolic health
We conducted a pilot study to see how vitamin D3 supplementation impacts individuals with obstructive sleep apnea (OSA). Our double-blind, randomized, placebo-controlled trial involved 19 Caucasian adults with OSA, some of whom were already using continuous positive airways pressure (CPAP) therapy.

Over a 15-week period, participants took either 4,000 IU of vitamin D3 or a placebo. We assessed various outcomes, including drowsiness, quality of life, fatigue levels, and cognitive function. While we observed a significant increase in vitamin D levels among those who received the supplement, we found that it did not improve symptoms related to sleepiness, quality of life, or cognitive performance.

Interestingly, we did notice a decrease in certain metabolic markers, suggesting that vitamin D3 may play a role in improving metabolic health among OSA patients. Overall, while vitamin D3 showed promise in enhancing metabolic parameters, it didn’t seem to alleviate the primary symptoms of OSA. Our findings pave the way for larger studies to further explore these effects.
Read More
8
Vitamin D linked to sleep apnea severity
We aimed to explore the connection between serum vitamin D levels and the severity of obstructive sleep apnea syndrome (OSAS), particularly in patients also dealing with metabolic syndrome, known as Syndrome Z. Our study involved 270 individuals diagnosed with both conditions. We gathered important data on various aspects, including demographics, sleep patterns, and laboratory results.

From our findings, we observed that a significant number of participants had varying degrees of OSAS severity. Notably, there was a clear trend showing that as the severity of OSAS increased, vitamin D levels decreased. After accounting for various factors, we found a strong association between lower serum 25(OH)D3 levels and greater OSAS severity.

This suggests that monitoring vitamin D levels in patients with the dual challenges of metabolic syndrome and sleep apnea could be vital. While our study highlights an association, we noted it does not directly address the effectiveness of vitamin D3 treatment for improving sleep apnea. Therefore, further research is needed to determine whether boosting vitamin D levels can positively impact sleep apnea symptoms.
Read More

Most Useful Reviews

9
Better sleep observed
2 people found this helpful
I have been taking one capsule before bed for about a week, and now I can sleep soundly until morning. The capsule size is small and easy to swallow.
Read More
9
Much improved sleep
1 people found this helpful
Convenient capsules have led to significantly better sleep quality for me.
Read More
7.5
Sleep improvement noticed
1 people found this helpful
I prefer this vitamin D with K, taking it in the evening. It appears to help my sleep.
Read More

Medical Researches

SCIENTIFIC SCORE
Possibly Effective
Based on 3 Researches
7
  • All Researches
We set out to evaluate what effect vitamin D3 supplementation might have on patients suffering from mild obstructive sleep apnea syndrome (OSAS). In this study, 19 adult men who were diagnosed with mild OSAS and had low vitamin D levels participated over an 8-week period. Each week, they took a sizable dose of 50,000 IU of vitamin D3 while undergoing various health assessments. We measured important factors like blood glucose, lipid profiles, and inflammation markers, along with repeated sleep monitoring through polysomnography.

By the end of the study, we observed a significant increase in participants' vitamin D levels, which jumped from an average of 19.5 to 41.8 ng/mL—an indication that the supplementation was effective. Along with this rise in vitamin D, we also noted improvements in fasting blood glucose and total cholesterol levels, as well as a decrease in key inflammation markers. Most encouragingly, the frequency of obstructive apneas and other related sleep disturbances significantly decreased.

Based on these findings, it seems that vitamin D supplementation can play a beneficial role in improving the prognosis for those with mild OSAS. It's exciting to consider how something as simple as a vitamin could lead to better sleep health for individuals struggling with sleep apnea.
Read More
8
Vitamin D linked to sleep apnea severity
We aimed to explore the connection between serum vitamin D levels and the severity of obstructive sleep apnea syndrome (OSAS), particularly in patients also dealing with metabolic syndrome, known as Syndrome Z. Our study involved 270 individuals diagnosed with both conditions. We gathered important data on various aspects, including demographics, sleep patterns, and laboratory results.

From our findings, we observed that a significant number of participants had varying degrees of OSAS severity. Notably, there was a clear trend showing that as the severity of OSAS increased, vitamin D levels decreased. After accounting for various factors, we found a strong association between lower serum 25(OH)D3 levels and greater OSAS severity.

This suggests that monitoring vitamin D levels in patients with the dual challenges of metabolic syndrome and sleep apnea could be vital. While our study highlights an association, we noted it does not directly address the effectiveness of vitamin D3 treatment for improving sleep apnea. Therefore, further research is needed to determine whether boosting vitamin D levels can positively impact sleep apnea symptoms.
Read More
4
Vitamin D3 enhances metabolic health
We conducted a pilot study to see how vitamin D3 supplementation impacts individuals with obstructive sleep apnea (OSA). Our double-blind, randomized, placebo-controlled trial involved 19 Caucasian adults with OSA, some of whom were already using continuous positive airways pressure (CPAP) therapy.

Over a 15-week period, participants took either 4,000 IU of vitamin D3 or a placebo. We assessed various outcomes, including drowsiness, quality of life, fatigue levels, and cognitive function. While we observed a significant increase in vitamin D levels among those who received the supplement, we found that it did not improve symptoms related to sleepiness, quality of life, or cognitive performance.

Interestingly, we did notice a decrease in certain metabolic markers, suggesting that vitamin D3 may play a role in improving metabolic health among OSA patients. Overall, while vitamin D3 showed promise in enhancing metabolic parameters, it didn’t seem to alleviate the primary symptoms of OSA. Our findings pave the way for larger studies to further explore these effects.
Read More

User Reviews

USERS' SCORE
Good
Based on 12 Reviews
8.2
  • All Reviews
  • Positive Reviews
  • Negative Reviews
9
Better sleep observed
2 people found this helpful
I have been taking one capsule before bed for about a week, and now I can sleep soundly until morning. The capsule size is small and easy to swallow.
Read More
9
Much improved sleep
1 people found this helpful
Convenient capsules have led to significantly better sleep quality for me.
Read More
7.5
Sleep improvement noticed
1 people found this helpful
I prefer this vitamin D with K, taking it in the evening. It appears to help my sleep.
Read More
9
Improved sleep quality
Recently, I've struggled with sleep and overall fatigue. After nearly finishing a bottle, I can confidently say it helped significantly. I now fall asleep quickly and wake feeling revitalised. Iodine deficiency in our water necessitates ongoing supplementation, along with K2 for circulation, especially in winter.
Read More
9
Amazing improvements
It feels good after taking it for a week; I’ve noticeably improved my sleep quality. It’s remarkable!
Read More

Frequently Asked Questions

9
Better sleep observed
2 people found this helpful
I have been taking one capsule before bed for about a week, and now I can sleep soundly until morning. The capsule size is small and easy to swallow.
9
Amazing improvements
It feels good after taking it for a week; I’ve noticeably improved my sleep quality. It’s remarkable!
7.5
Significant health improvement
2 people found this helpful
After taking one capsule daily for two months, I will now take one every other day for two months. My general condition improved greatly. I stopped catching colds, slept better, and felt excellent physically. However, after two months, I experienced headaches for two weeks after taking the pill, leading me to stop. I'm currently on a break, as I suspect I may have overdosed.
9
Improved sleep quality
Recently, I've struggled with sleep and overall fatigue. After nearly finishing a bottle, I can confidently say it helped significantly. I now fall asleep quickly and wake feeling revitalised. Iodine deficiency in our water necessitates ongoing supplementation, along with K2 for circulation, especially in winter.
7.5
Improved alertness
After taking these vitamins, my condition has improved significantly. I no longer feel the need to sleep excessively, unlike before when I was constantly drowsy. I learned that Vitamin D needs to be paired with Vitamin K for better absorption, which is why I opted for this combination.
7.5
Sleep improvement noticed
1 people found this helpful
I prefer this vitamin D with K, taking it in the evening. It appears to help my sleep.
7.5
Improved focus and energy
5 people found this helpful
Vitamins D and K2 together are well-regarded for health. I've noticed more energy, along with improvements in my nails and hair. Many users also report better sleep and increased focus. Overall, this combination may support wellness and health, though consulting a doctor is advisable before starting any new supplements.
We set out to evaluate what effect vitamin D3 supplementation might have on patients suffering from mild obstructive sleep apnea syndrome (OSAS). In this study, 19 adult men who were diagnosed with mild OSAS and had low vitamin D levels participated over an 8-week period. Each week, they took a sizable dose of 50,000 IU of vitamin D3 while undergoing various health assessments. We measured important factors like blood glucose, lipid profiles, and inflammation markers, along with repeated sleep monitoring through polysomnography.

By the end of the study, we observed a significant increase in participants' vitamin D levels, which jumped from an average of 19.5 to 41.8 ng/mL—an indication that the supplementation was effective. Along with this rise in vitamin D, we also noted improvements in fasting blood glucose and total cholesterol levels, as well as a decrease in key inflammation markers. Most encouragingly, the frequency of obstructive apneas and other related sleep disturbances significantly decreased.

Based on these findings, it seems that vitamin D supplementation can play a beneficial role in improving the prognosis for those with mild OSAS. It's exciting to consider how something as simple as a vitamin could lead to better sleep health for individuals struggling with sleep apnea.
8
Vitamin D linked to sleep apnea severity
We aimed to explore the connection between serum vitamin D levels and the severity of obstructive sleep apnea syndrome (OSAS), particularly in patients also dealing with metabolic syndrome, known as Syndrome Z. Our study involved 270 individuals diagnosed with both conditions. We gathered important data on various aspects, including demographics, sleep patterns, and laboratory results.

From our findings, we observed that a significant number of participants had varying degrees of OSAS severity. Notably, there was a clear trend showing that as the severity of OSAS increased, vitamin D levels decreased. After accounting for various factors, we found a strong association between lower serum 25(OH)D3 levels and greater OSAS severity.

This suggests that monitoring vitamin D levels in patients with the dual challenges of metabolic syndrome and sleep apnea could be vital. While our study highlights an association, we noted it does not directly address the effectiveness of vitamin D3 treatment for improving sleep apnea. Therefore, further research is needed to determine whether boosting vitamin D levels can positively impact sleep apnea symptoms.
4
Vitamin D3 enhances metabolic health
We conducted a pilot study to see how vitamin D3 supplementation impacts individuals with obstructive sleep apnea (OSA). Our double-blind, randomized, placebo-controlled trial involved 19 Caucasian adults with OSA, some of whom were already using continuous positive airways pressure (CPAP) therapy.

Over a 15-week period, participants took either 4,000 IU of vitamin D3 or a placebo. We assessed various outcomes, including drowsiness, quality of life, fatigue levels, and cognitive function. While we observed a significant increase in vitamin D levels among those who received the supplement, we found that it did not improve symptoms related to sleepiness, quality of life, or cognitive performance.

Interestingly, we did notice a decrease in certain metabolic markers, suggesting that vitamin D3 may play a role in improving metabolic health among OSA patients. Overall, while vitamin D3 showed promise in enhancing metabolic parameters, it didn’t seem to alleviate the primary symptoms of OSA. Our findings pave the way for larger studies to further explore these effects.

References

  1. Kilavuz A, Celikhisar H, Dasdemir Ilkhan G. The Association of Serum 25(OH) Vitamin D Level with Severity of Obstructive Sleep Apnea Syndrome in Patients with Syndrome Z (the Interaction of Obstructive Sleep Apnea with Metabolic Syndrome). Metab Syndr Relat Disord. 2021;19:549. 10.1089/met.2021.0066
  2. Ayyıldız F, Yıldıran H, Afandiyeva N, Gülbahar Ö, Köktürk O. The effects of vitamin D supplemantation on prognosis in patients with mild obstructive sleep apnea syndrome. Turk J Med Sci. 2021;51:2524. 10.3906/sag-2101-83
  3. Kerley CP, Hutchinson K, Bramham J, McGowan A, Faul J, et al. Vitamin D Improves Selected Metabolic Parameters but Not Neuropsychological or Quality of Life Indices in OSA: A Pilot Study. J Clin Sleep Med. 2017;13:19. 10.5664/jcsm.6378
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