' 
SCIENTIFIC SCORE
Moderately Effective
Based on 7 Researches
8.3
USERS' SCORE
Moderately Good
Based on 1 Review
7.8
Supplement Facts
Serving Size: 1 Vegetarian Capsule
Amount Per Serving
%DV
Magnesium [as magnesium oxide, citrate, succinate)
500 mg
119%
Top Medical Research Studies
9
Magnesium's effect on colitis
Improvement of magnesium isoglycyrrhizinate on DSS-induced acute and chronic colitis.
Focused on isolated magnesium effect
We investigated the potential benefits of magnesium isoglycyrrhizinate in treating colitis induced by dextran sulfate sodium (DSS). Our findings suggest that magnesium isoglycyrrhizinate can effectively alleviate both acute and chronic symptoms of colitis.
The treatment helped reduce inflammation by lowering the number of immune cells in the affected areas and decreasing levels of inflammatory cytokines. Additionally, we noted it significantly reduced reactive oxygen species (ROS) levels and mitigated the damage to the gut barrier associated with DSS treatment.
Another key observation was the treatment's ability to decrease colonic fibrosis, a common complication of IBD. Overall, these results indicate that magnesium isoglycyrrhizinate shows promise in managing intestinal inflammation and could be beneficial for people suffering from inflammatory bowel disease in clinical settings.
The treatment helped reduce inflammation by lowering the number of immune cells in the affected areas and decreasing levels of inflammatory cytokines. Additionally, we noted it significantly reduced reactive oxygen species (ROS) levels and mitigated the damage to the gut barrier associated with DSS treatment.
Another key observation was the treatment's ability to decrease colonic fibrosis, a common complication of IBD. Overall, these results indicate that magnesium isoglycyrrhizinate shows promise in managing intestinal inflammation and could be beneficial for people suffering from inflammatory bowel disease in clinical settings.
Read More
9
Magnesium aids colitis treatment
Dietary Magnesium Alleviates Experimental Murine Colitis through Modulation of Gut Microbiota.
High relevance to magnesium and colitis
We examined the impact of magnesium on colitis, particularly focusing on how magnesium supplementation could improve gut health. In a controlled murine model of colitis, induced by dextran sodium sulfate, we monitored several factors, including magnesium levels in the blood, weight changes, and the consistency of feces.
Our exploration revealed that adding magnesium to the diet led to a richer gut microbiota in mice with colitis. Specifically, we observed an increase in beneficial bacteria, while the levels of harmful bacteria, such as Enterobacteriaceae, were reduced.
Furthermore, the analysis suggested that when magnesium was supplemented, there was enhanced biosynthetic activity and vital DNA repair processes occurring in the gut. Meanwhile, low magnesium levels seemed to support more harmful, catabolic processes.
These findings indicate that magnesium supplementation may be a helpful and cost-effective approach to alleviate symptoms of colitis and support overall gut microbiome health in individuals suffering from inflammatory bowel diseases.
Our exploration revealed that adding magnesium to the diet led to a richer gut microbiota in mice with colitis. Specifically, we observed an increase in beneficial bacteria, while the levels of harmful bacteria, such as Enterobacteriaceae, were reduced.
Furthermore, the analysis suggested that when magnesium was supplemented, there was enhanced biosynthetic activity and vital DNA repair processes occurring in the gut. Meanwhile, low magnesium levels seemed to support more harmful, catabolic processes.
These findings indicate that magnesium supplementation may be a helpful and cost-effective approach to alleviate symptoms of colitis and support overall gut microbiome health in individuals suffering from inflammatory bowel diseases.
Read More
9
Magnesium improves colitis symptoms
Dietary Magnesium Alleviates Experimental Murine Colitis Through Upregulation of the Transient Receptor Potential Melastatin 6 Channel.
Directly assesses magnesium's impact
We explored the potential benefits of magnesium for people suffering from inflammatory bowel disease (IBD), particularly how its availability might influence colitis. The study involved measuring magnesium levels in IBD patients and investigating the effects of dietary magnesium in mice with colitis induced by dextran sodium sulfate (DSS).
Our findings revealed that a significant number of IBD patients had low magnesium levels, which were linked to increased disease activity. In the murine model, those on a magnesium-deficient diet experienced exacerbated colitis symptoms, highlighting how this deficiency can worsen inflammation and complicate the recovery of intestinal health.
However, we observed that supplementing magnesium not only improved magnesium levels but also aid in restoring the intestinal barrier, particularly by enhancing the expression of TRPM6 channels in the gut. This suggests that magnesium could be a safe and effective addition to treatment strategies for managing colitis and might help restore normal gut function.
Our findings revealed that a significant number of IBD patients had low magnesium levels, which were linked to increased disease activity. In the murine model, those on a magnesium-deficient diet experienced exacerbated colitis symptoms, highlighting how this deficiency can worsen inflammation and complicate the recovery of intestinal health.
However, we observed that supplementing magnesium not only improved magnesium levels but also aid in restoring the intestinal barrier, particularly by enhancing the expression of TRPM6 channels in the gut. This suggests that magnesium could be a safe and effective addition to treatment strategies for managing colitis and might help restore normal gut function.
Read More
Most Useful Reviews
1.3
Not suitable for colitis
Avoid this if you have colitis. Fellow sufferers of pseudomembranous colitis, unless you seek uncontrollable diarrhoea alongside your usual issues, this product is not for you. Instead, I recommend magnesium glycinate, as this disease impairs magnesium absorption. This supplement is not suitable for us. I don't hold the manufacturer responsible, but they should have listed this common side effect.
Read More
Medical Researches
SCIENTIFIC SCORE
Moderately Effective
Based on 7 Researches
8.3
- All Researches
9
Magnesium aids colitis treatment
Dietary Magnesium Alleviates Experimental Murine Colitis through Modulation of Gut Microbiota.
High relevance to magnesium and colitis
We examined the impact of magnesium on colitis, particularly focusing on how magnesium supplementation could improve gut health. In a controlled murine model of colitis, induced by dextran sodium sulfate, we monitored several factors, including magnesium levels in the blood, weight changes, and the consistency of feces.
Our exploration revealed that adding magnesium to the diet led to a richer gut microbiota in mice with colitis. Specifically, we observed an increase in beneficial bacteria, while the levels of harmful bacteria, such as Enterobacteriaceae, were reduced.
Furthermore, the analysis suggested that when magnesium was supplemented, there was enhanced biosynthetic activity and vital DNA repair processes occurring in the gut. Meanwhile, low magnesium levels seemed to support more harmful, catabolic processes.
These findings indicate that magnesium supplementation may be a helpful and cost-effective approach to alleviate symptoms of colitis and support overall gut microbiome health in individuals suffering from inflammatory bowel diseases.
Our exploration revealed that adding magnesium to the diet led to a richer gut microbiota in mice with colitis. Specifically, we observed an increase in beneficial bacteria, while the levels of harmful bacteria, such as Enterobacteriaceae, were reduced.
Furthermore, the analysis suggested that when magnesium was supplemented, there was enhanced biosynthetic activity and vital DNA repair processes occurring in the gut. Meanwhile, low magnesium levels seemed to support more harmful, catabolic processes.
These findings indicate that magnesium supplementation may be a helpful and cost-effective approach to alleviate symptoms of colitis and support overall gut microbiome health in individuals suffering from inflammatory bowel diseases.
Read More
9
Magnesium's effect on colitis
Improvement of magnesium isoglycyrrhizinate on DSS-induced acute and chronic colitis.
Focused on isolated magnesium effect
We investigated the potential benefits of magnesium isoglycyrrhizinate in treating colitis induced by dextran sulfate sodium (DSS). Our findings suggest that magnesium isoglycyrrhizinate can effectively alleviate both acute and chronic symptoms of colitis.
The treatment helped reduce inflammation by lowering the number of immune cells in the affected areas and decreasing levels of inflammatory cytokines. Additionally, we noted it significantly reduced reactive oxygen species (ROS) levels and mitigated the damage to the gut barrier associated with DSS treatment.
Another key observation was the treatment's ability to decrease colonic fibrosis, a common complication of IBD. Overall, these results indicate that magnesium isoglycyrrhizinate shows promise in managing intestinal inflammation and could be beneficial for people suffering from inflammatory bowel disease in clinical settings.
The treatment helped reduce inflammation by lowering the number of immune cells in the affected areas and decreasing levels of inflammatory cytokines. Additionally, we noted it significantly reduced reactive oxygen species (ROS) levels and mitigated the damage to the gut barrier associated with DSS treatment.
Another key observation was the treatment's ability to decrease colonic fibrosis, a common complication of IBD. Overall, these results indicate that magnesium isoglycyrrhizinate shows promise in managing intestinal inflammation and could be beneficial for people suffering from inflammatory bowel disease in clinical settings.
Read More
9
Magnesium improves colitis symptoms
Dietary Magnesium Alleviates Experimental Murine Colitis Through Upregulation of the Transient Receptor Potential Melastatin 6 Channel.
Directly assesses magnesium's impact
We explored the potential benefits of magnesium for people suffering from inflammatory bowel disease (IBD), particularly how its availability might influence colitis. The study involved measuring magnesium levels in IBD patients and investigating the effects of dietary magnesium in mice with colitis induced by dextran sodium sulfate (DSS).
Our findings revealed that a significant number of IBD patients had low magnesium levels, which were linked to increased disease activity. In the murine model, those on a magnesium-deficient diet experienced exacerbated colitis symptoms, highlighting how this deficiency can worsen inflammation and complicate the recovery of intestinal health.
However, we observed that supplementing magnesium not only improved magnesium levels but also aid in restoring the intestinal barrier, particularly by enhancing the expression of TRPM6 channels in the gut. This suggests that magnesium could be a safe and effective addition to treatment strategies for managing colitis and might help restore normal gut function.
Our findings revealed that a significant number of IBD patients had low magnesium levels, which were linked to increased disease activity. In the murine model, those on a magnesium-deficient diet experienced exacerbated colitis symptoms, highlighting how this deficiency can worsen inflammation and complicate the recovery of intestinal health.
However, we observed that supplementing magnesium not only improved magnesium levels but also aid in restoring the intestinal barrier, particularly by enhancing the expression of TRPM6 channels in the gut. This suggests that magnesium could be a safe and effective addition to treatment strategies for managing colitis and might help restore normal gut function.
Read More
8
Hypermagnesemia linked to colitis
Impaired consciousness due to hypermagnesemia associated with stercoral colitis: report of a rare case.
Highlights link between bowel health
We encountered a rare and intriguing case involving a 75-year-old woman who presented with impaired consciousness linked to hypermagnesemia—a significant increase in magnesium levels. The connection we observed was particularly striking, as this situation arose in the absence of magnesium supplementation, drawing our attention to the potential role of severe bowel dysfunction in increasing magnesium concentrations.
The patient exhibited symptoms like a distended abdomen, hypotension, and cognitive impairment, all pointing toward serious underlying issues. Through abdominal imaging, we found evidence of fecal impaction, leading to what is known as stercoral colitis. The elevated magnesium levels truly puzzled us, especially since there was no history of magnesium administration, prompting us to consider that severe bowel dysfunction could independently contribute to hypermagnesemia.
After treatment, including calcium administration and measures to address the fecal impaction, the patient's magnesium levels and consciousness improved. This case illustrates that magnesium levels can rise dangerously high with severe intestinal issues without direct magnesium intake, suggesting a complex interplay between the gut and electrolyte balance that merits further investigation.
The patient exhibited symptoms like a distended abdomen, hypotension, and cognitive impairment, all pointing toward serious underlying issues. Through abdominal imaging, we found evidence of fecal impaction, leading to what is known as stercoral colitis. The elevated magnesium levels truly puzzled us, especially since there was no history of magnesium administration, prompting us to consider that severe bowel dysfunction could independently contribute to hypermagnesemia.
After treatment, including calcium administration and measures to address the fecal impaction, the patient's magnesium levels and consciousness improved. This case illustrates that magnesium levels can rise dangerously high with severe intestinal issues without direct magnesium intake, suggesting a complex interplay between the gut and electrolyte balance that merits further investigation.
Read More
8
Magnesium intake reduces UC risk
Dietary Magnesium Intake Is Inversely Associated With Ulcerative Colitis: A Case-Control Study.
Study directly assesses magnesium's impact
We conducted a case-control study to explore how dietary magnesium intake relates to ulcerative colitis (UC). By analyzing 109 UC patients alongside 218 matched individuals without the condition, we aimed to uncover if magnesium could play a protective role against UC.
Participants reported their dietary intake using a comprehensive Food Frequency Questionnaire that allowed us to assess their magnesium consumption levels. Our findings revealed that those in the highest intake group were significantly less likely to have UC compared to those in the lowest group, showing an odds ratio of 0.32 in the unadjusted model.
After accounting for various potential confounding factors, the association remained strong, with an adjusted odds ratio of 0.30. This suggests that higher magnesium intake may be linked to a lower risk of developing ulcerative colitis, highlighting the importance of a magnesium-rich diet.
However, while these results are promising, we acknowledge the need for further research to fully understand the role of magnesium in preventing UC.
Participants reported their dietary intake using a comprehensive Food Frequency Questionnaire that allowed us to assess their magnesium consumption levels. Our findings revealed that those in the highest intake group were significantly less likely to have UC compared to those in the lowest group, showing an odds ratio of 0.32 in the unadjusted model.
After accounting for various potential confounding factors, the association remained strong, with an adjusted odds ratio of 0.30. This suggests that higher magnesium intake may be linked to a lower risk of developing ulcerative colitis, highlighting the importance of a magnesium-rich diet.
However, while these results are promising, we acknowledge the need for further research to fully understand the role of magnesium in preventing UC.
Read More
User Reviews
USERS' SCORE
Moderately Good
Based on 1 Review
7.8
- All Reviews
- Positive Reviews
- Negative Reviews
1.3
Not suitable for colitis
Avoid this if you have colitis. Fellow sufferers of pseudomembranous colitis, unless you seek uncontrollable diarrhoea alongside your usual issues, this product is not for you. Instead, I recommend magnesium glycinate, as this disease impairs magnesium absorption. This supplement is not suitable for us. I don't hold the manufacturer responsible, but they should have listed this common side effect.
Read More
