Overview
SCIENTIFIC SCORE
Possibly Effective
Based on 16 Researches
7.4
USERS' SCORE
Good
Based on 48 Reviews
8.1
Supplement Facts
Serving Size: 1 Vegetarian Capsule
Amount Per Serving
%DV
Magnesium [as magnesium oxide, citrate, succinate)
500 mg
119%
Top Medical Research Studies
7
We examined how magnesium supplements might influence heart failure and serious heart-related issues in diabetic patients.
In a study involving over 94,000 veterans, we found that those taking magnesium supplements experienced a lower risk of heart failure compared to nonusers. Specifically, 8.0% of supplement users developed heart failure, versus 9.7% of nonusers.
Furthermore, magnesium intake was linked to a reduced chance of major adverse cardiac events. However, it’s important to note that these findings need further investigation through randomized controlled trials.
In a study involving over 94,000 veterans, we found that those taking magnesium supplements experienced a lower risk of heart failure compared to nonusers. Specifically, 8.0% of supplement users developed heart failure, versus 9.7% of nonusers.
Furthermore, magnesium intake was linked to a reduced chance of major adverse cardiac events. However, it’s important to note that these findings need further investigation through randomized controlled trials.
Read More
9
We explored how magnesium supplementation might influence mortality rates in patients with heart failure and preserved ejection fraction (HFpEF). The study involved nearly 2,000 patients, with careful matching to ensure a fair comparison between those receiving magnesium and those who weren’t.
Interestingly, we found that magnesium intake was linked to a significant reduction in 28-day mortality rates. This effect was most notable in older adults, women, and patients with high blood pressure. Despite these positive findings, magnesium treatment did lead to longer hospital and ICU stays.
Overall, magnesium shows promise as a supportive treatment for HFpEF, but further investigation is necessary to better understand its benefits and implications.
Interestingly, we found that magnesium intake was linked to a significant reduction in 28-day mortality rates. This effect was most notable in older adults, women, and patients with high blood pressure. Despite these positive findings, magnesium treatment did lead to longer hospital and ICU stays.
Overall, magnesium shows promise as a supportive treatment for HFpEF, but further investigation is necessary to better understand its benefits and implications.
Read More
8
Magnesium levels and heart disease mortality
We examined the link between serum magnesium levels and the risk of death from heart failure, coronary heart disease, and stroke in patients with chronic kidney disease who don’t require dialysis. Over a decade, we followed 1,271 patients, noting that those with higher magnesium levels experienced significantly lower mortality rates from these conditions.
This suggests that maintaining adequate magnesium levels may help improve health outcomes for individuals with advanced kidney issues and an increased risk of cardiovascular problems.
This suggests that maintaining adequate magnesium levels may help improve health outcomes for individuals with advanced kidney issues and an increased risk of cardiovascular problems.
Read More
Most Useful Reviews
9
Aids heart recovery
219 people found this helpful
Quality magnesium for recovery after intense workouts. It has notably improved my heart health, especially post-leg workouts. I recommend taking it with food, ideally in the evening, and consider adding zinc and BCAA for optimal results.
Read More
9
Restores magnesium balance
35 people found this helpful
My magnesium levels were low, affecting my mood and causing muscle spasms. Since taking this, I've experienced a significant improvement, resolving my symptoms and supporting my health.
Read More
9
Nervous exhaustion relief
32 people found this helpful
Excellent! Doctors recommend magnesium for muscle weakness, nervous exhaustion, and chronic fatigue. After two weeks of taking it, I noticed a significant improvement: I became calmer and less anxious. Thank you, iHerb!
Read More
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 16 Researches
7.4
- All Researches
9
We explored how magnesium supplementation might influence mortality rates in patients with heart failure and preserved ejection fraction (HFpEF). The study involved nearly 2,000 patients, with careful matching to ensure a fair comparison between those receiving magnesium and those who weren’t.
Interestingly, we found that magnesium intake was linked to a significant reduction in 28-day mortality rates. This effect was most notable in older adults, women, and patients with high blood pressure. Despite these positive findings, magnesium treatment did lead to longer hospital and ICU stays.
Overall, magnesium shows promise as a supportive treatment for HFpEF, but further investigation is necessary to better understand its benefits and implications.
Interestingly, we found that magnesium intake was linked to a significant reduction in 28-day mortality rates. This effect was most notable in older adults, women, and patients with high blood pressure. Despite these positive findings, magnesium treatment did lead to longer hospital and ICU stays.
Overall, magnesium shows promise as a supportive treatment for HFpEF, but further investigation is necessary to better understand its benefits and implications.
Read More
8
Magnesium levels and heart disease mortality
We examined the link between serum magnesium levels and the risk of death from heart failure, coronary heart disease, and stroke in patients with chronic kidney disease who don’t require dialysis. Over a decade, we followed 1,271 patients, noting that those with higher magnesium levels experienced significantly lower mortality rates from these conditions.
This suggests that maintaining adequate magnesium levels may help improve health outcomes for individuals with advanced kidney issues and an increased risk of cardiovascular problems.
This suggests that maintaining adequate magnesium levels may help improve health outcomes for individuals with advanced kidney issues and an increased risk of cardiovascular problems.
Read More
8
Magnesium intake impacts heart disease risk
We explored the link between magnesium intake and heart disease risk in young adults, using a comprehensive study of U.S. adults aged 20 to 34. This cross-sectional research analyzed data from the National Health and Nutrition Examination Survey, examining dietary habits and various cardiovascular factors.
Our findings suggest that higher magnesium intake is associated with a lower risk of future cardiovascular issues and non-HDL cholesterol problems. This suggests that including magnesium-rich foods in our diets could promote heart health early in life.
Our findings suggest that higher magnesium intake is associated with a lower risk of future cardiovascular issues and non-HDL cholesterol problems. This suggests that including magnesium-rich foods in our diets could promote heart health early in life.
Read More
8
We analyzed several clinical trials to examine how magnesium and potassium affect systolic blood pressure (SBP) in healthy individuals. Our findings showed that magnesium significantly reduced SBP, especially at lower doses (up to 360 mg/day) and longer treatment periods of over three months. Potassium also played a role but was effective at higher doses and shorter durations.
However, both supplements showed promise in lowering SBP but did not seem to drastically change heart disease risk directly. Further studies will help confirm our results and refine dosage recommendations for better health outcomes.
However, both supplements showed promise in lowering SBP but did not seem to drastically change heart disease risk directly. Further studies will help confirm our results and refine dosage recommendations for better health outcomes.
Read More
8
We explored how the serum calcium-magnesium ratio impacts outcomes in patients with acute coronary syndrome (ACS) by analyzing data from 1,775 individuals who underwent coronary procedures over five years.
By categorizing patients based on their calcium-magnesium levels at admission, we discovered that a higher calcium-to-magnesium ratio correlated with worse outcomes.
Our findings suggest that monitoring this ratio could help predict the prognosis for those dealing with ACS, emphasizing the importance of maintaining a balanced mineral intake for heart health.
By categorizing patients based on their calcium-magnesium levels at admission, we discovered that a higher calcium-to-magnesium ratio correlated with worse outcomes.
Our findings suggest that monitoring this ratio could help predict the prognosis for those dealing with ACS, emphasizing the importance of maintaining a balanced mineral intake for heart health.
Read More
User Reviews
USERS' SCORE
Good
Based on 48 Reviews
8.1
- All Reviews
- Positive Reviews
- Negative Reviews
9
Aids heart recovery
219 people found this helpful
Quality magnesium for recovery after intense workouts. It has notably improved my heart health, especially post-leg workouts. I recommend taking it with food, ideally in the evening, and consider adding zinc and BCAA for optimal results.
Read More
9
Restores magnesium balance
35 people found this helpful
My magnesium levels were low, affecting my mood and causing muscle spasms. Since taking this, I've experienced a significant improvement, resolving my symptoms and supporting my health.
Read More
9
Nervous exhaustion relief
32 people found this helpful
Excellent! Doctors recommend magnesium for muscle weakness, nervous exhaustion, and chronic fatigue. After two weeks of taking it, I noticed a significant improvement: I became calmer and less anxious. Thank you, iHerb!
Read More
9
Pregnancy support
25 people found this helpful
Magnesium is crucial after 30, especially during pregnancy. I experienced constant cramps due to low magnesium. Once I started taking it, the cramps ceased. Magnesium promotes bone growth, regulates heart rate, and lowers blood pressure.
Read More
9
Supports heart function
23 people found this helpful
This magnesium helped significantly with my heart issue after a cardiologist's diagnosis of tachycardia. I noticed improvements within a week, particularly due to its chelated forms that enhance absorption.
Read More
Frequently Asked Questions
9
Supports heart function
23 people found this helpful
This magnesium helped significantly with my heart issue after a cardiologist's diagnosis of tachycardia. I noticed improvements within a week, particularly due to its chelated forms that enhance absorption.
9
Reduces heart pain
1 people found this helpful
I began using magnesium for heart pain, noticing a 90 percent decrease in discomfort after two weeks. It benefits my overall health, particularly for the heart, muscles, and joints, while also improving sleep quality. Magnesium is truly essential for our body.
7.5
Fights insomnia
4 people found this helpful
After a month of use, I've noticed significant improvements in my sleep and energy levels. This magnesium supplement aids carbohydrate metabolism, stabilises hormones, and relieves muscle cramps while positively impacting my central nervous system.
9
Nervous exhaustion relief
32 people found this helpful
Excellent! Doctors recommend magnesium for muscle weakness, nervous exhaustion, and chronic fatigue. After two weeks of taking it, I noticed a significant improvement: I became calmer and less anxious. Thank you, iHerb!
9
Pregnancy support
25 people found this helpful
Magnesium is crucial after 30, especially during pregnancy. I experienced constant cramps due to low magnesium. Once I started taking it, the cramps ceased. Magnesium promotes bone growth, regulates heart rate, and lowers blood pressure.
9
Aids heart recovery
219 people found this helpful
Quality magnesium for recovery after intense workouts. It has notably improved my heart health, especially post-leg workouts. I recommend taking it with food, ideally in the evening, and consider adding zinc and BCAA for optimal results.
7.5
Daily heart support
10 people found this helpful
Excellent magnesium! One capsule per day suffices, unlike others requiring more. My parents take it at night; it aids sleep but sometimes causes a laxative effect. I recommend combining it with B vitamins for heart treatment.
7.5
Supports heart health
401 people found this helpful
Very good magnesium complex. It supports cardiovascular health and promotes brain function. I gave it to my father, who has heart disease, taking one capsule daily. Highly recommend!
9
Sleep improvement
2 people found this helpful
This product is a fantastic support. After a week of taking 500 mg daily, I noticed improvements in my sleep quality and reduced irritability. It aids in treating heart disease by calming the nerves and enhancing mental productivity.
1
Caused heart palpitations
3 people found this helpful
Initially, I experienced strong heart palpitations and anxiety after taking one capsule, which also led to diarrhoea. After trying a half capsule, the palpitations lessened, but I still felt uneasy about its benefits for my sleep and heart disease.
7
We examined how magnesium supplements might influence heart failure and serious heart-related issues in diabetic patients.
In a study involving over 94,000 veterans, we found that those taking magnesium supplements experienced a lower risk of heart failure compared to nonusers. Specifically, 8.0% of supplement users developed heart failure, versus 9.7% of nonusers.
Furthermore, magnesium intake was linked to a reduced chance of major adverse cardiac events. However, it’s important to note that these findings need further investigation through randomized controlled trials.
In a study involving over 94,000 veterans, we found that those taking magnesium supplements experienced a lower risk of heart failure compared to nonusers. Specifically, 8.0% of supplement users developed heart failure, versus 9.7% of nonusers.
Furthermore, magnesium intake was linked to a reduced chance of major adverse cardiac events. However, it’s important to note that these findings need further investigation through randomized controlled trials.
8
Magnesium levels and heart disease mortality
We examined the link between serum magnesium levels and the risk of death from heart failure, coronary heart disease, and stroke in patients with chronic kidney disease who don’t require dialysis. Over a decade, we followed 1,271 patients, noting that those with higher magnesium levels experienced significantly lower mortality rates from these conditions.
This suggests that maintaining adequate magnesium levels may help improve health outcomes for individuals with advanced kidney issues and an increased risk of cardiovascular problems.
This suggests that maintaining adequate magnesium levels may help improve health outcomes for individuals with advanced kidney issues and an increased risk of cardiovascular problems.
7
We investigated the effect of magnesium and calcium on blood sugar levels in 11,934 patients with coronary artery disease. Our findings indicated that higher serum magnesium levels and a favorable magnesium to calcium ratio were associated with lower abnormal HbA1c levels, which reflect better blood sugar management. In contrast, calcium showed no significant association with HbA1c levels. Importantly, we found no evidence that inflammation played a role in this relationship. Overall, magnesium might be beneficial for maintaining healthy blood sugar levels in those with heart disease.
References
- Cheng Y, Zullo AR, Yin Y, Shao Y, Liu S, et al. Nonprescription Magnesium Supplement Use and Risk of Heart Failure in Patients With Diabetes: A Target Trial Emulation. J Am Heart Assoc. 2025;14:e038870. 10.1161/JAHA.124.038870
- Moyano-Peregrin C, Rodelo-Haad C, Martín-Malo A, Muñoz-Castañeda JR, Ojeda R, et al. Upper normal serum magnesium is associated with a reduction in incident death from fatal heart failure, coronary heart disease and stroke in non-dialysis patients with CKD stages 4 and 5. Clin Kidney J. 2025;18:sfae390. 10.1093/ckj/sfae390
- Dong H, Lu N, Wang J, Hu P. Serum magnesium, not calcium, is inversely associated with abnormal HbA1c concentrations in adults with coronary artery disease. Asia Pac J Clin Nutr. 2025;34:104. 10.6133/apjcn.202502_34(1).0010
- Song L, Ying J, Li M, Ying L, Zhao C. Propensity score matched cohort study on magnesium supplementation and mortality in critically ill patients with HFpEF. Sci Rep. 2025;15:1944. 10.1038/s41598-025-85931-1
- Sun L, Du J. Magnesium status, serum vitamin D concentration and mortality among congestive heart failure patients: a cohort study from NHANES 2007-2018. Magnes Res. 2024;37:61. 10.1684/mrh.2024.0528
- Song Q, Song L, Liu H, Tan H, Yang B, et al. Association of magnesium intake with predicted atherosclerotic lesions and cardiovascular risk in young adults based on PDAY score: a cross-sectional study. BMC Public Health. 2024;24:3232. 10.1186/s12889-024-20785-2
- Behers BJ, Behers BM, Stephenson-Moe CA, Vargas IA, Meng Z, et al. Magnesium and Potassium Supplementation for Systolic Blood Pressure Reduction in the General Normotensive Population: A Systematic Review and Subgroup Meta-Analysis for Optimal Dosage and Treatment Length. Nutrients. 2024;16. 10.3390/nu16213617
- Jiang Y, Luo B, Chen Y, Lu W, Peng Y, et al. Serum calcium-magnesium ratio at admission predicts adverse outcomes in patients with acute coronary syndrome. PLoS One. 2024;19:e0313352. 10.1371/journal.pone.0313352
- Wyss C, Gündling PW, Kostev K. Real world effectiveness of Hawthorn special extract WS 1442 in a retrospective cohort study from Germany. Sci Rep. 2024;14:22986. 10.1038/s41598-024-74325-4
- Seguchi M, Aytekin A, Xhepa E, Haude M, Wlodarczak A, et al. Vascular response following implantation of the third-generation drug-eluting resorbable coronary magnesium scaffold: an intravascular imaging analysis of the BIOMAG-I first-in-human study. EuroIntervention. 2024;20:e1173. 10.4244/EIJ-D-24-00055
- Zhang J, Chen Z, Rao L, He Y. Coronary bioresorbable metallic stents: Advancements and future perspectives. J Cardiol. 2025;85:69. 10.1016/j.jjcc.2024.08.003
- Copp KL, Steffen LM, Yi SY, Lutsey PL, Rebholz CM, et al. Magnesium-rich diet score is inversely associated with incident cardiovascular disease: the Atherosclerosis Risk in Communities (ARIC) study. Eur J Prev Cardiol. 2025;32:386. 10.1093/eurjpc/zwae251
- Zhuang J, Zhang Q, Wang H, Su PH, Chen PY. Association between short-term changes in serum magnesium and in-hospital mortality following acute myocardial infarction: a cohort study based on the MIMIC database. Magnes Res. 2024;37:45. 10.1684/mrh.2024.0517
- Fruh V, Babalola T, Sears C, Wellenius GA, Webster TF, et al. Dietary Minerals and Incident Cardiovascular Outcomes among Never-Smokers in a Danish Case-Cohort Study. Int J Environ Res Public Health. 2024;21. 10.3390/ijerph21070932
- Tao J, Wang J, Peng H, Yuan Y, Lai H, et al. Association between serum phosphate, magnesium, calcium and aortic valve sclerosis: a propensity score-matched case-control study. Acta Cardiol. 2024;79:522. 10.1080/00015385.2024.2379682
- Zhang J, Sun D, Guo Y, Tong J, Liu Q, et al. Targeted delivery of black phosphorus nanosheets by ROS responsive complex hydrogel based on angiogenesis and antioxidant promotes myocardial infarction repair. J Nanobiotechnology. 2024;22:433. 10.1186/s12951-024-02685-0
