Overview

SCIENTIFIC SCORE
Moderately Effective
Based on 16 Researches
8
USERS' SCORE
Good
Based on 15 Reviews
8.7
Supplement Facts
Serving Size: 1 Vegetarian Capsule
Amount Per Serving
%DV
Magnesium [as magnesium oxide, citrate, succinate)
500 mg
119%

Top Medical Research Studies

9
Magnesium sulfate alleviates postoperative pain
We explored the impact of magnesium sulfate on managing pain following total knee arthroplasty. In a randomized, double-blind trial with 90 patients, half received a blend of analgesics that included magnesium sulfate, while the other half did not.

Following surgery, the results showed that magnesium sulfate helped prolong pain relief and reduced the need for opioids. Patients receiving it experienced less postoperative pain and moved towards recovery more effectively.

Overall, adding magnesium sulfate appears beneficial for postoperative knee pain management.
Read More
9
Magnesium aids postoperative pain relief
We explored the role of magnesium in reducing knee pain following total knee arthroplasty (TKA). In a study involving 119 adults, participants received either an adductor canal block with magnesium and bupivacaine or just bupivacaine.

Those who received magnesium reported significantly lower pain scores and reduced opioid usage in the days after surgery, without experiencing an uptick in nausea or dissatisfaction. This suggests that adding magnesium to local anesthesia could enhance pain management for TKA patients, promoting a smoother recovery.
Read More
9
Magnesium reduces postoperative knee pain
We evaluated the impact of magnesium sulphate on pain levels for 44 patients undergoing staged bilateral total knee arthroplasty.

In this study, the magnesium group received magnesium sulphate while the control group received isotonic saline during their surgeries.

Our findings showed that those who received magnesium experienced significantly lower pain scores compared to the control group, both after their first and second surgeries.

Importantly, magnesium also helped reduce the need for additional pain relief medications in the days following surgery.
Read More

Most Useful Reviews

9
Alleviated knee pain
17 people found this helpful
I started taking magnesium to combat my back pain and was pleasantly surprised to find my knee pain improved as well. It's remarkable how quickly the pain alleviated, though skipping doses does bring back the discomfort!
Read More
9
Calf pain alleviated
1 people found this helpful
After beginning daily magnesium, my calf pain and knee pain have significantly decreased, allowing me to wear high heels again after years. It's made a noticeable difference in my comfort.
Read More
9
No more knee pain
1 people found this helpful
Two months of using this magnesium has completely eliminated my knee pain and muscle cramps. I sleep better now, and I’m impressed with the ingredient quality.
Read More

Medical Researches

SCIENTIFIC SCORE
Moderately Effective
Based on 16 Researches
8
  • All Researches
9
Magnesium sulfate alleviates postoperative pain
We explored the impact of magnesium sulfate on managing pain following total knee arthroplasty. In a randomized, double-blind trial with 90 patients, half received a blend of analgesics that included magnesium sulfate, while the other half did not.

Following surgery, the results showed that magnesium sulfate helped prolong pain relief and reduced the need for opioids. Patients receiving it experienced less postoperative pain and moved towards recovery more effectively.

Overall, adding magnesium sulfate appears beneficial for postoperative knee pain management.
Read More
9
Magnesium aids postoperative pain relief
We explored the role of magnesium in reducing knee pain following total knee arthroplasty (TKA). In a study involving 119 adults, participants received either an adductor canal block with magnesium and bupivacaine or just bupivacaine.

Those who received magnesium reported significantly lower pain scores and reduced opioid usage in the days after surgery, without experiencing an uptick in nausea or dissatisfaction. This suggests that adding magnesium to local anesthesia could enhance pain management for TKA patients, promoting a smoother recovery.
Read More
9
Magnesium and bupivacaine effective
We evaluated how effective magnesium, especially when combined with bupivacaine, is for managing knee pain after arthroscopy. Our study looked at data from 78 randomized trials involving 4,425 participants.

It turns out that magnesium with bupivacaine is the top performer in easing pain right after surgery and at the 24-hour mark, outperforming other analgesics like morphine.

However, magnesium alone didn’t show significant pain relief. We found that using this combination does not lead to more side effects, making it a safe choice for recovery.
Read More
9
Magnesium reduces postoperative knee pain
We evaluated the impact of magnesium sulphate on pain levels for 44 patients undergoing staged bilateral total knee arthroplasty.

In this study, the magnesium group received magnesium sulphate while the control group received isotonic saline during their surgeries.

Our findings showed that those who received magnesium experienced significantly lower pain scores compared to the control group, both after their first and second surgeries.

Importantly, magnesium also helped reduce the need for additional pain relief medications in the days following surgery.
Read More
9
Magnesium reduces post-surgery pain
We looked into how magnesium can help ease knee pain after total knee arthroplasty. In a study of 80 patients, those who received an injection of magnesium sulfate and ropivacaine experienced significantly less pain and needed less morphine compared to those who got a saline injection. This approach not only reduced morphine use in the first 48 hours but also allowed patients to regain movement quicker. Overall, our findings suggest that magnesium may be a beneficial part of pain management in knee surgery.
Read More

User Reviews

USERS' SCORE
Good
Based on 15 Reviews
8.7
  • All Reviews
  • Positive Reviews
  • Negative Reviews
9
Alleviated knee pain
17 people found this helpful
I started taking magnesium to combat my back pain and was pleasantly surprised to find my knee pain improved as well. It's remarkable how quickly the pain alleviated, though skipping doses does bring back the discomfort!
Read More
9
Calf pain alleviated
1 people found this helpful
After beginning daily magnesium, my calf pain and knee pain have significantly decreased, allowing me to wear high heels again after years. It's made a noticeable difference in my comfort.
Read More
9
No more knee pain
1 people found this helpful
Two months of using this magnesium has completely eliminated my knee pain and muscle cramps. I sleep better now, and I’m impressed with the ingredient quality.
Read More
9
Eliminated knee pain
407 people found this helpful
My intestines struggled with magnesium for a while, but this product agrees with me completely. I initially experienced abdominal pain and gas with other brands but felt no such issues here. My family and I are now sleeping soundly! I can genuinely recommend it.
Read More
9
Reduced joint pain
134 people found this helpful
This magnesium supports my nervous system and brain, effectively alleviating my knee pain. I feel much better overall and no longer have nocturnal cramping in my foot. I'm definitely going to continue using it.
Read More

Frequently Asked Questions

9
Calf pain alleviated
1 people found this helpful
After beginning daily magnesium, my calf pain and knee pain have significantly decreased, allowing me to wear high heels again after years. It's made a noticeable difference in my comfort.
9
No more knee pain
1 people found this helpful
Two months of using this magnesium has completely eliminated my knee pain and muscle cramps. I sleep better now, and I’m impressed with the ingredient quality.
7.5
Good sleep aid
The quality and packaging are good. I find that it helps with my knee pain and improves my sleep without any taste. I’ve started noticing the benefits after regular use.
7.5
Excellent endurance
1 people found this helpful
One of the best types of magnesium. If you experience knee pain or muscle discomfort, using this supplement will yield noticeable improvements day by day, especially with exercise. My mood and endurance have significantly enhanced, and my sleep quality has improved. I wake up feeling refreshed and active. Thank you, Harb, for these robust and beneficial products.
9
Alleviated knee pain
17 people found this helpful
I started taking magnesium to combat my back pain and was pleasantly surprised to find my knee pain improved as well. It's remarkable how quickly the pain alleviated, though skipping doses does bring back the discomfort!
7.5
Joint pain relief
8 people found this helpful
This magnesium has been wonderful in managing joint pain. I've also integrated it with collagen, and the combination has notably helped alleviate my knee pain. There has definitely been a positive effect!
7.5
Improved knee health
Since taking this with collagen, my knee pain has improved significantly.
7.5
Knee pain relief
1 people found this helpful
This quality magnesium is a combination of three types, all of which have helped alleviate my knee pain and assist with better sleep. It’s essential to my routine, particularly when paired with potassium for calcium absorption.
7.5
Improved knee comfort
10 people found this helpful
My mother took this magnesium for over a month, and it really reduced her joint pain, particularly in her knees. Only one capsule a day is needed, and it has improved her sleep and mood significantly. I highly recommend this quality product!
7
Magnesium aids knee surgery recovery
We investigated how magnesium sulfate influences recovery after knee surgery. In our study, 148 elderly patients undergoing total knee arthroplasty were divided into two groups: one received magnesium sulfate, while the other received a saline solution.

This double-blind setup allowed us to see if magnesium sulfate could enhance recovery quality after surgery. Our findings indicate that magnesium sulfate does help reduce early postoperative pain and improves overall recovery in these patients.

Overall, magnesium sulfate appears beneficial in managing pain during the recovery process.
8
Magnesium reduces knee surgery pain
We assessed whether adding magnesium sulfate to a conventional pain relief cocktail could enhance comfort for those undergoing total knee arthroplasty. In a carefully designed study involving 100 participants, half received the modified approach while the other half got the standard mix.

Notably, results showed that the modified cocktail significantly eased postoperative pain, leading to a reduction in opioid use. This suggests a promising advancement in pain management strategies for knee surgeries.
7
Magnesium intake impacts knee pain
We explored whether magnesium intake affects knee pain and function in individuals with knee osteoarthritis. In a study involving over 2,500 participants, we followed their magnesium intake for 48 months.

Our findings showed that lower magnesium intake was linked to worse pain and reduced function over time. This trend was particularly noticeable in people who also had low fiber intake. These results suggest that maintaining adequate magnesium levels could be beneficial for managing knee pain.

References

  1. Zhu Y, Shen S, Cui L, Wu L, Zhang B. Magnesium sulphate and sodium bicarbonate as additives for periarticular local infiltration analgesia improve pain management after unicompartmental knee arthroplasty: a prospective, double-blind, randomized controlled trial. J Orthop Surg Res. 2024;19:764. 10.1186/s13018-024-05233-6
  2. Xu H, Hao C, Wang X, Du J, Zhang T, et al. Effect of Magnesium Sulfate Infusion on Postoperative Quality of Recovery in Patients Undergoing Total Knee Arthroplasty: A Prospective, Double-Blind, Randomized Controlled Trial. Drug Des Devel Ther. 2024;18:919. 10.2147/DDDT.S444896
  3. Zhao C, Wang L, Chen L, Wang Q, Kang P. Effects of magnesium sulfate on periarticular infiltration analgesia in total knee arthroplasty: a prospective, double-blind, randomized controlled trial. J Orthop Surg Res. 2023;18:301. 10.1186/s13018-023-03790-w
  4. Wang Q, Zhao C, Hu J, Ma T, Yang J, et al. Efficacy of a Modified Cocktail for Periarticular Local Infiltration Analgesia in Total Knee Arthroplasty: A Prospective, Double-Blinded, Randomized Controlled Trial. J Bone Joint Surg Am. 2023;105:354. 10.2106/JBJS.22.00614
  5. Choi JW, Lahori A, Merlo JA, Gill O, Ghoddoussi F, et al. Adductor Canal Blocks With Bupivacaine and Magnesium After Same-day Discharge Total Knee Arthroplasty Improve Postoperative Pain Relief and Decrease Opioid Consumption: A Prospective Randomized Controlled Trial. Clin J Pain. 2022;38:388. 10.1097/AJP.0000000000001036
  6. He Y, He H, Li X, Lei G, Xie D, et al. Intra-Articular Magnesium Plus Bupivacaine Is the Most Effective and Safe Postoperative Analgesic Option Following Knee Arthroscopy: A Network Meta-analysis. Arthroscopy. 2022;38:2897. 10.1016/j.arthro.2022.03.013
  7. Shi L, Zhu H, Ma J, Shi LL, Gao F, et al. Intra-articular magnesium to alleviate postoperative pain after arthroscopic knee surgery: a meta-analysis of randomized controlled trials. J Orthop Surg Res. 2021;16:111. 10.1186/s13018-021-02264-1
  8. Zhao Z, Zhang X, Peng H, Li W, Liu H, et al. Magnesium Sulfate Combined with a Levobupivacaine Periarticular Cocktail for Analgesia in the Early Postoperative Period after Total Knee Arthroplasty. J Knee Surg. 2021;34:1463. 10.1055/s-0040-1710364
  9. Condello V, Filardo G, Madonna V, Andriolo L, Screpis D, et al. Use of a Biomimetic Scaffold for the Treatment of Osteochondral Lesions in Early Osteoarthritis. Biomed Res Int. 2018;2018:7937089. 10.1155/2018/7937089
  10. Shmagel A, Onizuka N, Langsetmo L, Vo T, Foley R, et al. Low magnesium intake is associated with increased knee pain in subjects with radiographic knee osteoarthritis: data from the Osteoarthritis Initiative. Osteoarthritis Cartilage. 2018;26:651. 10.1016/j.joca.2018.02.002
  11. Shin HJ, Kim EY, Na HS, Kim TK, Kim MH, et al. Magnesium sulphate attenuates acute postoperative pain and increased pain intensity after surgical injury in staged bilateral total knee arthroplasty: a randomized, double-blinded, placebo-controlled trial. Br J Anaesth. 2016;117:497. 10.1093/bja/aew227
  12. Chen Y, Zhang Y, Zhu YL, Fu PL. Efficacy and safety of an intra-operative intra-articular magnesium/ropivacaine injection for pain control following total knee arthroplasty. J Int Med Res. 2012;40:2032.
  13. Ekmekci P, Bengisun ZK, Akan B, Kazbek BK, Ozkan KS, et al. The effect of magnesium added to levobupivacaine for femoral nerve block on postoperative analgesia in patients undergoing ACL reconstruction. Knee Surg Sports Traumatol Arthrosc. 2013;21:1119. 10.1007/s00167-012-2093-4
  14. Koltka K, Koknel-Talu G, Asik M, Ozyalcin S. Comparison of efficacy of intraarticular application of magnesium, levobupivacaine and lornoxicam with placebo in arthroscopic surgery. Knee Surg Sports Traumatol Arthrosc. 2011;19:1884. 10.1007/s00167-011-1497-x
  15. Chen Y, Zhang Y, Zhu YL, Fu PL. Efficacy and safety of an intra-operative intra-articular magnesium/ropivacaine injection for pain control following total knee arthroplasty. J Int Med Res. 2009;37:1733.
  16. Farouk S, Aly A. A comparison of intra-articular magnesium and/or morphine with bupivacaine for postoperative analgesia after arthroscopic knee surgery. J Anesth. 2009;23:508. 10.1007/s00540-009-0822-8
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