Overview
SCIENTIFIC SCORE
Possibly Effective
Based on 3 Researches
7.3
USERS' SCORE
Good
Based on 52 Reviews
8.5
Supplement Facts
Serving Size: 1 Capsule
Amount Per Serving
%DV
N-acetyl-L-cysteine
600 mg
**
Top Medical Research Studies
8
We explored how N-acetylcysteine (NAC), a common mucolytic agent, plays a role in treating bronchitis associated with chronic obstructive pulmonary disease (COPD). This study focused on the treatable traits (TT) strategy, which aims to identify and manage specific traits of COPD that are clinically significant and manageable.
Our findings indicate that NAC is particularly valuable for patients experiencing a frequent productive cough, a common trait of bronchitis in COPD. Not only does it help reduce mucus buildup, but it also appears to have benefits for reducing airway inflammation and limitations in airflow.
Interestingly, the research highlights that NAC’s antioxidant and anti-inflammatory properties can support various symptoms linked to bronchitis. By adopting the TT strategy, including NAC in the treatment plan, we observed improvements in lung function and overall quality of life for patients, while minimizing unnecessary medication.
Thus, incorporating NAC into bronchitis management within the framework of personalized medicine shows promising potential to help patients manage their symptoms better and enhance their daily lives.
Our findings indicate that NAC is particularly valuable for patients experiencing a frequent productive cough, a common trait of bronchitis in COPD. Not only does it help reduce mucus buildup, but it also appears to have benefits for reducing airway inflammation and limitations in airflow.
Interestingly, the research highlights that NAC’s antioxidant and anti-inflammatory properties can support various symptoms linked to bronchitis. By adopting the TT strategy, including NAC in the treatment plan, we observed improvements in lung function and overall quality of life for patients, while minimizing unnecessary medication.
Thus, incorporating NAC into bronchitis management within the framework of personalized medicine shows promising potential to help patients manage their symptoms better and enhance their daily lives.
Read More
7
Our investigation delves into how N-acetylcysteine (NAC) impacts the treatment of bronchitis when used alongside phage therapy. We specifically looked at the interactions between NAC and certain bacterial strains known to cause lower respiratory tract infections.
Through our study, we discovered that NAC could act as an adjuvant, enhancing the effectiveness of phages in fighting these bacterial pathogens. Under certain conditions, NAC appeared to make bacteria more susceptible to phage infection, which could facilitate better treatment outcomes.
However, we also noted that the effectiveness of this combination depends on various factors, including the specific characteristics of the phages and the surrounding environment. Different outcomes were observed in terms of how phages interacted with bacteria, emphasizing the need for further research to fully understand this complex relationship.
Overall, this study provides insights into optimizing treatment strategies for bronchitis, especially in an era of rising antibiotic resistance, by combining mucoactive agents like NAC with innovative therapies such as phage therapy.
Through our study, we discovered that NAC could act as an adjuvant, enhancing the effectiveness of phages in fighting these bacterial pathogens. Under certain conditions, NAC appeared to make bacteria more susceptible to phage infection, which could facilitate better treatment outcomes.
However, we also noted that the effectiveness of this combination depends on various factors, including the specific characteristics of the phages and the surrounding environment. Different outcomes were observed in terms of how phages interacted with bacteria, emphasizing the need for further research to fully understand this complex relationship.
Overall, this study provides insights into optimizing treatment strategies for bronchitis, especially in an era of rising antibiotic resistance, by combining mucoactive agents like NAC with innovative therapies such as phage therapy.
Read More
7
We examined the effectiveness of n-acetyl-l-cysteine, a mucolytic agent, in treating patients with stable chronic obstructive pulmonary disease (COPD). In our analysis, we looked at randomized controlled trials which highlighted various mucolytics including n-acetyl-l-cysteine, ambroxol, and others.
While mucolytics like n-acetyl-l-cysteine showed promise in reducing exacerbations and hospitalizations among patients, it did not significantly improve other outcomes related to bronchitis or lung function, such as mortality or work absenteeism. The results suggested a reduction in the rate of exacerbations and a tendency towards better outcomes in those who experienced two or more exacerbations, yet no improvement was seen in overall lung function tests.
Importantly, the safety profile of mucolytics was comparable to that of a placebo, indicating that patients can tolerate this treatment without serious side effects. Overall, while we recognized some benefits, it is clear that n-acetyl-l-cysteine might not be a game changer for bronchitis management.
While mucolytics like n-acetyl-l-cysteine showed promise in reducing exacerbations and hospitalizations among patients, it did not significantly improve other outcomes related to bronchitis or lung function, such as mortality or work absenteeism. The results suggested a reduction in the rate of exacerbations and a tendency towards better outcomes in those who experienced two or more exacerbations, yet no improvement was seen in overall lung function tests.
Importantly, the safety profile of mucolytics was comparable to that of a placebo, indicating that patients can tolerate this treatment without serious side effects. Overall, while we recognized some benefits, it is clear that n-acetyl-l-cysteine might not be a game changer for bronchitis management.
Read More
Most Useful Reviews
9
Effective bronchitis treatment
158 people found this helpful
I was initially sceptical about the quality of Life Extension N-Acetyl-L-Cysteine (NAC) due to its lower price. However, I have found it very effective for treating bronchitis. Whenever I begin to cough or develop a cold, I start taking NAC, and it often prevents the bronchitis from worsening. It worked well for my latest cold, and I intend to keep using this brand because it’s effective and reasonably priced.
Read More
10
Breath easier now
130 people found this helpful
Absolutely love it! If you suffer from asthma, COPD, chronic bronchitis, or feel a cold settling in your chest, take this! I’ve struggled with chronic allergies that escalate into chest issues. I started taking two daily for a couple of weeks to support my breathing. I hadn't been able to inflate a balloon for years without feeling dizzy! This past summer, I inflated multiple pool floats simultaneously; the only product I was using was N-Acetyl Cysteine. Each time I tested this product, I achieved positive results! I wholeheartedly recommend it for anyone facing breathing challenges. It's safe, affordable, and effective!
Read More
9
Excellent for bronchitis
15 people found this helpful
This treatment is like an emergency remedy for coughs and bronchitis. It significantly helps in clearing phlegm from the lungs, working better than other substitutes like ACC. It's particularly useful post-bronchitis and after illnesses such as COVID-19. Plus, it effectively detoxifies the body after a night of drinking. Highly recommend!
Read More
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 3 Researches
7.3
- All Researches
8
We explored how N-acetylcysteine (NAC), a common mucolytic agent, plays a role in treating bronchitis associated with chronic obstructive pulmonary disease (COPD). This study focused on the treatable traits (TT) strategy, which aims to identify and manage specific traits of COPD that are clinically significant and manageable.
Our findings indicate that NAC is particularly valuable for patients experiencing a frequent productive cough, a common trait of bronchitis in COPD. Not only does it help reduce mucus buildup, but it also appears to have benefits for reducing airway inflammation and limitations in airflow.
Interestingly, the research highlights that NAC’s antioxidant and anti-inflammatory properties can support various symptoms linked to bronchitis. By adopting the TT strategy, including NAC in the treatment plan, we observed improvements in lung function and overall quality of life for patients, while minimizing unnecessary medication.
Thus, incorporating NAC into bronchitis management within the framework of personalized medicine shows promising potential to help patients manage their symptoms better and enhance their daily lives.
Our findings indicate that NAC is particularly valuable for patients experiencing a frequent productive cough, a common trait of bronchitis in COPD. Not only does it help reduce mucus buildup, but it also appears to have benefits for reducing airway inflammation and limitations in airflow.
Interestingly, the research highlights that NAC’s antioxidant and anti-inflammatory properties can support various symptoms linked to bronchitis. By adopting the TT strategy, including NAC in the treatment plan, we observed improvements in lung function and overall quality of life for patients, while minimizing unnecessary medication.
Thus, incorporating NAC into bronchitis management within the framework of personalized medicine shows promising potential to help patients manage their symptoms better and enhance their daily lives.
Read More
7
Our investigation delves into how N-acetylcysteine (NAC) impacts the treatment of bronchitis when used alongside phage therapy. We specifically looked at the interactions between NAC and certain bacterial strains known to cause lower respiratory tract infections.
Through our study, we discovered that NAC could act as an adjuvant, enhancing the effectiveness of phages in fighting these bacterial pathogens. Under certain conditions, NAC appeared to make bacteria more susceptible to phage infection, which could facilitate better treatment outcomes.
However, we also noted that the effectiveness of this combination depends on various factors, including the specific characteristics of the phages and the surrounding environment. Different outcomes were observed in terms of how phages interacted with bacteria, emphasizing the need for further research to fully understand this complex relationship.
Overall, this study provides insights into optimizing treatment strategies for bronchitis, especially in an era of rising antibiotic resistance, by combining mucoactive agents like NAC with innovative therapies such as phage therapy.
Through our study, we discovered that NAC could act as an adjuvant, enhancing the effectiveness of phages in fighting these bacterial pathogens. Under certain conditions, NAC appeared to make bacteria more susceptible to phage infection, which could facilitate better treatment outcomes.
However, we also noted that the effectiveness of this combination depends on various factors, including the specific characteristics of the phages and the surrounding environment. Different outcomes were observed in terms of how phages interacted with bacteria, emphasizing the need for further research to fully understand this complex relationship.
Overall, this study provides insights into optimizing treatment strategies for bronchitis, especially in an era of rising antibiotic resistance, by combining mucoactive agents like NAC with innovative therapies such as phage therapy.
Read More
7
We examined the effectiveness of n-acetyl-l-cysteine, a mucolytic agent, in treating patients with stable chronic obstructive pulmonary disease (COPD). In our analysis, we looked at randomized controlled trials which highlighted various mucolytics including n-acetyl-l-cysteine, ambroxol, and others.
While mucolytics like n-acetyl-l-cysteine showed promise in reducing exacerbations and hospitalizations among patients, it did not significantly improve other outcomes related to bronchitis or lung function, such as mortality or work absenteeism. The results suggested a reduction in the rate of exacerbations and a tendency towards better outcomes in those who experienced two or more exacerbations, yet no improvement was seen in overall lung function tests.
Importantly, the safety profile of mucolytics was comparable to that of a placebo, indicating that patients can tolerate this treatment without serious side effects. Overall, while we recognized some benefits, it is clear that n-acetyl-l-cysteine might not be a game changer for bronchitis management.
While mucolytics like n-acetyl-l-cysteine showed promise in reducing exacerbations and hospitalizations among patients, it did not significantly improve other outcomes related to bronchitis or lung function, such as mortality or work absenteeism. The results suggested a reduction in the rate of exacerbations and a tendency towards better outcomes in those who experienced two or more exacerbations, yet no improvement was seen in overall lung function tests.
Importantly, the safety profile of mucolytics was comparable to that of a placebo, indicating that patients can tolerate this treatment without serious side effects. Overall, while we recognized some benefits, it is clear that n-acetyl-l-cysteine might not be a game changer for bronchitis management.
Read More
User Reviews
USERS' SCORE
Good
Based on 52 Reviews
8.5
- All Reviews
- Positive Reviews
- Negative Reviews
9
Effective bronchitis treatment
158 people found this helpful
I was initially sceptical about the quality of Life Extension N-Acetyl-L-Cysteine (NAC) due to its lower price. However, I have found it very effective for treating bronchitis. Whenever I begin to cough or develop a cold, I start taking NAC, and it often prevents the bronchitis from worsening. It worked well for my latest cold, and I intend to keep using this brand because it’s effective and reasonably priced.
Read More
10
Breath easier now
130 people found this helpful
Absolutely love it! If you suffer from asthma, COPD, chronic bronchitis, or feel a cold settling in your chest, take this! I’ve struggled with chronic allergies that escalate into chest issues. I started taking two daily for a couple of weeks to support my breathing. I hadn't been able to inflate a balloon for years without feeling dizzy! This past summer, I inflated multiple pool floats simultaneously; the only product I was using was N-Acetyl Cysteine. Each time I tested this product, I achieved positive results! I wholeheartedly recommend it for anyone facing breathing challenges. It's safe, affordable, and effective!
Read More
9
Excellent for bronchitis
15 people found this helpful
This treatment is like an emergency remedy for coughs and bronchitis. It significantly helps in clearing phlegm from the lungs, working better than other substitutes like ACC. It's particularly useful post-bronchitis and after illnesses such as COVID-19. Plus, it effectively detoxifies the body after a night of drinking. Highly recommend!
Read More
9
Convenient bronchitis relief
10 people found this helpful
NAC has proven to be effective for chronic bronchitis, facilitating excellent expectoration. The small capsules are convenient to use; I found the best results when taken with carbonated mineral water. Truly a wondrous remedy.
Read More
9
Anti-inflammatory properties
10 people found this helpful
Life Extension N-Acetyl-L-Cysteine has been a remarkable find as it possesses both antitoxic and antioxidant properties. It effectively supports lung health and reduces the frequency of bronchitis exacerbations. I had no allergic reactions, and the capsules are comfortable to take. I hope my review helps others in their search for effective treatments.
Read More
Frequently Asked Questions
7.5
Immune support noted
1 people found this helpful
Very good! It supports the immune system against bronchitis and improves overall well-being. The benefits were evident by the second week for me. Everything else is fine.
9
Rapid recovery
3 people found this helpful
I took this during my bronchitis treatment, and I believe it helped expedite my recovery. I recommend it.
8.5
Eases symptoms
2 people found this helpful
This reputable product significantly aided my brother's recovery from severe bronchitis. I trust this brand and noticed a remarkable reduction in his pain and cough due to its mucolytic properties. I recommend it to those affected by COVID-19.
9
Excellent for bronchitis
15 people found this helpful
This treatment is like an emergency remedy for coughs and bronchitis. It significantly helps in clearing phlegm from the lungs, working better than other substitutes like ACC. It's particularly useful post-bronchitis and after illnesses such as COVID-19. Plus, it effectively detoxifies the body after a night of drinking. Highly recommend!
9
Effective bronchitis treatment
158 people found this helpful
I was initially sceptical about the quality of Life Extension N-Acetyl-L-Cysteine (NAC) due to its lower price. However, I have found it very effective for treating bronchitis. Whenever I begin to cough or develop a cold, I start taking NAC, and it often prevents the bronchitis from worsening. It worked well for my latest cold, and I intend to keep using this brand because it’s effective and reasonably priced.
9
Quick bronchitis recovery
1 people found this helpful
Excellent! The medication helped me quickly recover from bronchitis, eliminating lingering cough. NAC is a mucolytic, expectorant, and antioxidant that did not upset my stomach unlike others.
10
Seasonal bronchitis relief
1 people found this helpful
It's a lifesaver against my seasonal bronchitis. I used to suffer greatly until I discovered NAC, which has diminished my excessive coughing. I’m very content with it, and it’s always in my medical kit.
7.5
Mucolytic enhancement
1 people found this helpful
When taken with glycine, NAC can enhance glutathione levels, aiding liver detoxification. It has mucolytic properties, making it effective during colds with bronchitis.
7.5
Strong recommendation
1 people found this helpful
I gave NAC to a sick friend with bronchitis. After using it, both she and her mother felt better post-coronavirus! It’s superior to other pharmacy alternatives. Highly recommended!
9
Effective for clearing lungs
5 people found this helpful
I have chronic bronchitis and other conditions from long-term nasal discharge. I found that NAC helps clear my lungs remarkably well. The 600mg dosage per pill is convenient and effective, and I’m pleased with the brand's quality.
10
Prevents chest infections
8 people found this helpful
Before taking this daily, I used to frequently get chest infections after just a cold. Now, if I do get one, it’s much milder. I believe N-acetyl cysteine works similarly for me as it does for cystic fibrosis patients. If you have similar issues, I recommend trying it.
9
Improved breathing
9 people found this helpful
This supplement supports healthy lung function and helps clear mucus, particularly useful for bronchitis. After suffering from pneumonia, I take one capsule daily to cleanse my lungs and aid sputum production. I noticed an improvement in my breathing and overall condition. I will certainly purchase it again.
7.5
Effective phlegm reduction
2 people found this helpful
I take NAC as directed by my therapist for bronchitis related to acute respiratory infections. It effectively clears phlegm. Recently, I have also used it to enhance liver detoxification. If taken at night, it may induce coughing if phlegm is present. Occasionally, it causes brief stomach discomfort when consumed on an empty stomach.
8
We explored how N-acetylcysteine (NAC), a common mucolytic agent, plays a role in treating bronchitis associated with chronic obstructive pulmonary disease (COPD). This study focused on the treatable traits (TT) strategy, which aims to identify and manage specific traits of COPD that are clinically significant and manageable.
Our findings indicate that NAC is particularly valuable for patients experiencing a frequent productive cough, a common trait of bronchitis in COPD. Not only does it help reduce mucus buildup, but it also appears to have benefits for reducing airway inflammation and limitations in airflow.
Interestingly, the research highlights that NAC’s antioxidant and anti-inflammatory properties can support various symptoms linked to bronchitis. By adopting the TT strategy, including NAC in the treatment plan, we observed improvements in lung function and overall quality of life for patients, while minimizing unnecessary medication.
Thus, incorporating NAC into bronchitis management within the framework of personalized medicine shows promising potential to help patients manage their symptoms better and enhance their daily lives.
Our findings indicate that NAC is particularly valuable for patients experiencing a frequent productive cough, a common trait of bronchitis in COPD. Not only does it help reduce mucus buildup, but it also appears to have benefits for reducing airway inflammation and limitations in airflow.
Interestingly, the research highlights that NAC’s antioxidant and anti-inflammatory properties can support various symptoms linked to bronchitis. By adopting the TT strategy, including NAC in the treatment plan, we observed improvements in lung function and overall quality of life for patients, while minimizing unnecessary medication.
Thus, incorporating NAC into bronchitis management within the framework of personalized medicine shows promising potential to help patients manage their symptoms better and enhance their daily lives.
7
We examined the effectiveness of n-acetyl-l-cysteine, a mucolytic agent, in treating patients with stable chronic obstructive pulmonary disease (COPD). In our analysis, we looked at randomized controlled trials which highlighted various mucolytics including n-acetyl-l-cysteine, ambroxol, and others.
While mucolytics like n-acetyl-l-cysteine showed promise in reducing exacerbations and hospitalizations among patients, it did not significantly improve other outcomes related to bronchitis or lung function, such as mortality or work absenteeism. The results suggested a reduction in the rate of exacerbations and a tendency towards better outcomes in those who experienced two or more exacerbations, yet no improvement was seen in overall lung function tests.
Importantly, the safety profile of mucolytics was comparable to that of a placebo, indicating that patients can tolerate this treatment without serious side effects. Overall, while we recognized some benefits, it is clear that n-acetyl-l-cysteine might not be a game changer for bronchitis management.
While mucolytics like n-acetyl-l-cysteine showed promise in reducing exacerbations and hospitalizations among patients, it did not significantly improve other outcomes related to bronchitis or lung function, such as mortality or work absenteeism. The results suggested a reduction in the rate of exacerbations and a tendency towards better outcomes in those who experienced two or more exacerbations, yet no improvement was seen in overall lung function tests.
Importantly, the safety profile of mucolytics was comparable to that of a placebo, indicating that patients can tolerate this treatment without serious side effects. Overall, while we recognized some benefits, it is clear that n-acetyl-l-cysteine might not be a game changer for bronchitis management.
7
Our investigation delves into how N-acetylcysteine (NAC) impacts the treatment of bronchitis when used alongside phage therapy. We specifically looked at the interactions between NAC and certain bacterial strains known to cause lower respiratory tract infections.
Through our study, we discovered that NAC could act as an adjuvant, enhancing the effectiveness of phages in fighting these bacterial pathogens. Under certain conditions, NAC appeared to make bacteria more susceptible to phage infection, which could facilitate better treatment outcomes.
However, we also noted that the effectiveness of this combination depends on various factors, including the specific characteristics of the phages and the surrounding environment. Different outcomes were observed in terms of how phages interacted with bacteria, emphasizing the need for further research to fully understand this complex relationship.
Overall, this study provides insights into optimizing treatment strategies for bronchitis, especially in an era of rising antibiotic resistance, by combining mucoactive agents like NAC with innovative therapies such as phage therapy.
Through our study, we discovered that NAC could act as an adjuvant, enhancing the effectiveness of phages in fighting these bacterial pathogens. Under certain conditions, NAC appeared to make bacteria more susceptible to phage infection, which could facilitate better treatment outcomes.
However, we also noted that the effectiveness of this combination depends on various factors, including the specific characteristics of the phages and the surrounding environment. Different outcomes were observed in terms of how phages interacted with bacteria, emphasizing the need for further research to fully understand this complex relationship.
Overall, this study provides insights into optimizing treatment strategies for bronchitis, especially in an era of rising antibiotic resistance, by combining mucoactive agents like NAC with innovative therapies such as phage therapy.
References
- Sui B, Li X, Li N, Tao Y, Wang L, et al. Synergistic action of mucoactive drugs and phages against and . Microbiol Spectr. 2025;13:e0160124. doi:10.1128/spectrum.01601-24
- Scioscia G, Baraldi F, Bigoni T, Papi A, Vatrella A, et al. The precision medicine strategy to treat COPD pulmonary traits in clinical practice: The role of N-acetylcysteine. Respir Med. 2024;235:107865. doi:10.1016/j.rmed.2024.107865
- Ohnishi H, Tanimoto T, Inaba R, Eitoku M. Efficacy and safety of mucolytics in patients with stable chronic obstructive pulmonary disease: A systematic review and meta-analysis. Respir Investig. 2024;62:1168. doi:10.1016/j.resinv.2024.10.004
