Overview
SCIENTIFIC SCORE
Likely Very Effective
Based on 1 Research
9
USERS' SCORE
Good
Based on 180 Reviews
8.1
Supplement Facts
Serving Size: 1 Capsule
Amount Per Serving
%DV
N-acetyl-L-cysteine
600 mg
**
Top Medical Research Studies
9
N-acetylcysteine protects cold platelets
We explored the impact of N-acetylcysteine, an antioxidant, on the preservation of cold-stored platelets. The study focused on understanding how this treatment might reduce the harmful effects caused by reactive oxygen species (ROS) generated during cold storage.
Platelet concentrates were categorized into three groups: those stored at room temperature, those kept cold, and those cold-stored with added N-acetylcysteine at varying concentrations. After five days of storage, we measured ROS production, lipid peroxidation, platelet activation, and other quality indicators.
Our findings highlighted that N-acetylcysteine effectively diminished the production of ROS, thus protecting the cold-stored platelets from damage and premature clearance by the immune system in both lab settings and live models. Importantly, using the right amount of N-acetylcysteine significantly improved the survival of these platelets in circulation.
Overall, this study sheds light on the potential benefits of incorporating antioxidants in platelet storage practices to enhance their functionality and longevity.
Platelet concentrates were categorized into three groups: those stored at room temperature, those kept cold, and those cold-stored with added N-acetylcysteine at varying concentrations. After five days of storage, we measured ROS production, lipid peroxidation, platelet activation, and other quality indicators.
Our findings highlighted that N-acetylcysteine effectively diminished the production of ROS, thus protecting the cold-stored platelets from damage and premature clearance by the immune system in both lab settings and live models. Importantly, using the right amount of N-acetylcysteine significantly improved the survival of these platelets in circulation.
Overall, this study sheds light on the potential benefits of incorporating antioxidants in platelet storage practices to enhance their functionality and longevity.
Read More
Most Useful Reviews
9
Prevents bronchitis
158 people found this helpful
I was sceptical about this Life Extension N-Acetyl-L-Cysteine (NAC) given other brands I'd had. However, it worked as hoped during my cold, preventing bronchitis. As someone with early emphysema and COPD, I use it at the first sign of a cold to avoid doctor visits. This will be my go-to NAC, as it’s effective and reasonably priced.
Read More
9
Speeds up recovery
27 people found this helpful
Great for shortening a cold! I bought it in anticipation of the cold and flu season, needing it sooner than expected after catching my husband's cold. I started feeling sick on the 31st and took a 600mg capsule twice daily. By the 5th, I was back at work, feeling much better! This time, I expelled nasty mucus easily and avoided a prolonged upper respiratory infection. I consider this a record recovery time for me!
Read More
10
Significant cold remedy
24 people found this helpful
This is an excellent cold remedy. It’s an absolute analogue of ACC, with 60 capsules for the same price as 10 effervescent tablets! Acetylcysteine acts as a mucolytic, expectorant, and antioxidant agent for respiratory diseases. When I begin to feel aches, I take an ACC capsule at night. Stay healthy!
Read More
Medical Researches
SCIENTIFIC SCORE
Likely Very Effective
Based on 1 Research
9
- All Researches
9
N-acetylcysteine protects cold platelets
We explored the impact of N-acetylcysteine, an antioxidant, on the preservation of cold-stored platelets. The study focused on understanding how this treatment might reduce the harmful effects caused by reactive oxygen species (ROS) generated during cold storage.
Platelet concentrates were categorized into three groups: those stored at room temperature, those kept cold, and those cold-stored with added N-acetylcysteine at varying concentrations. After five days of storage, we measured ROS production, lipid peroxidation, platelet activation, and other quality indicators.
Our findings highlighted that N-acetylcysteine effectively diminished the production of ROS, thus protecting the cold-stored platelets from damage and premature clearance by the immune system in both lab settings and live models. Importantly, using the right amount of N-acetylcysteine significantly improved the survival of these platelets in circulation.
Overall, this study sheds light on the potential benefits of incorporating antioxidants in platelet storage practices to enhance their functionality and longevity.
Platelet concentrates were categorized into three groups: those stored at room temperature, those kept cold, and those cold-stored with added N-acetylcysteine at varying concentrations. After five days of storage, we measured ROS production, lipid peroxidation, platelet activation, and other quality indicators.
Our findings highlighted that N-acetylcysteine effectively diminished the production of ROS, thus protecting the cold-stored platelets from damage and premature clearance by the immune system in both lab settings and live models. Importantly, using the right amount of N-acetylcysteine significantly improved the survival of these platelets in circulation.
Overall, this study sheds light on the potential benefits of incorporating antioxidants in platelet storage practices to enhance their functionality and longevity.
Read More
User Reviews
USERS' SCORE
Good
Based on 180 Reviews
8.1
- All Reviews
- Positive Reviews
- Negative Reviews
9
Prevents bronchitis
158 people found this helpful
I was sceptical about this Life Extension N-Acetyl-L-Cysteine (NAC) given other brands I'd had. However, it worked as hoped during my cold, preventing bronchitis. As someone with early emphysema and COPD, I use it at the first sign of a cold to avoid doctor visits. This will be my go-to NAC, as it’s effective and reasonably priced.
Read More
9
Speeds up recovery
27 people found this helpful
Great for shortening a cold! I bought it in anticipation of the cold and flu season, needing it sooner than expected after catching my husband's cold. I started feeling sick on the 31st and took a 600mg capsule twice daily. By the 5th, I was back at work, feeling much better! This time, I expelled nasty mucus easily and avoided a prolonged upper respiratory infection. I consider this a record recovery time for me!
Read More
10
Significant cold remedy
24 people found this helpful
This is an excellent cold remedy. It’s an absolute analogue of ACC, with 60 capsules for the same price as 10 effervescent tablets! Acetylcysteine acts as a mucolytic, expectorant, and antioxidant agent for respiratory diseases. When I begin to feel aches, I take an ACC capsule at night. Stay healthy!
Read More
9
Relieves cold symptoms
3 people found this helpful
I find this N-Acetyl L-Cysteine excellent; I take it in various amounts for different purposes, like as a hot drink for a cold. It has an enjoyable taste, removes toxins, manages phlegm, eases my headache, and acts as an antioxidant. I will continue using it.
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9
Rapid relief
3 people found this helpful
At the first sign of a cold, if I feel phlegm beginning to form, I take one in the morning on an empty stomach, and all signs of a cold have disappeared in two days.
Read More
Frequently Asked Questions
9
Rapid relief
3 people found this helpful
At the first sign of a cold, if I feel phlegm beginning to form, I take one in the morning on an empty stomach, and all signs of a cold have disappeared in two days.
9
Quick relief
It lifts me instantly! I take it at the first signs of a cold at night, and by morning, I feel rejuvenated.
9
Immediate relief
A good product! I use it at the first signs of a cold, and it immediately relieves symptoms and shortens recovery time.
9
Good expectorant
I liked the product very much! I use it for colds, and it helps my body recover faster. It’s a good expectorant and liver aid.
9
Prevents bronchitis
158 people found this helpful
I was sceptical about this Life Extension N-Acetyl-L-Cysteine (NAC) given other brands I'd had. However, it worked as hoped during my cold, preventing bronchitis. As someone with early emphysema and COPD, I use it at the first sign of a cold to avoid doctor visits. This will be my go-to NAC, as it’s effective and reasonably priced.
10
Significant cold remedy
24 people found this helpful
This is an excellent cold remedy. It’s an absolute analogue of ACC, with 60 capsules for the same price as 10 effervescent tablets! Acetylcysteine acts as a mucolytic, expectorant, and antioxidant agent for respiratory diseases. When I begin to feel aches, I take an ACC capsule at night. Stay healthy!
9
Good for symptoms
An excellent drug we take as soon as the first signs of a cold emerge. It makes breathing much easier, and our family uses it together.
9
Thins phlegm quickly
It thins phlegm and helps a runny nose pass faster! For colds, it's number one! I always keep it in my first aid kit!
9
Best cold remedy
I always have this NAC in my medicine cabinet; for colds, I take it with a complete set of vitamins, and for mastopathy (oestrogen dominance), I also use it with other treatments. In my opinion, this is the best.
9
Prevents illness
I recommend it. Since starting these supplements, I haven’t fallen ill, which used to happen frequently. When my husband caught a cold, he felt better almost immediately after taking them for just two days.
9
Alleviates cold
I purchased this for an estrogen regulation protocol. Interestingly, I developed a cold while using it, but it significantly helped in clearing mucus. I highly recommend it.
References
- Xie R, Yang Y, Jiang X, Gao L, Sun J, et al. The effect of modulating platelet reactive oxygen species by the addition of antioxidants to prevent clearance of cold-stored platelets. Hematol Transfus Cell Ther. 2024;46 Suppl 6:S272. doi:10.1016/j.htct.2024.09.2479
