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SCIENTIFIC SCORE
Possibly Effective
Based on 4 Researches
7.5
USERS' SCORE
Good
Based on 1 Review
8.6
Supplement Facts
Serving Size: 3 Vegetarian Capsules
Amount Per Serving
%DV
Magnesium (from 2,000 mg Magtein® magnesium L-threonate)
144 mg
34%
Top Medical Research Studies
8
Magnesium sulfate aids pediatric asthma
Pharmacokinetics and Pharmacodynamics of Intravenous Magnesium Sulfate in Pediatric Acute Asthma Exacerbations.
Highly relevant asthma treatment study
We explored how intravenous magnesium sulfate (IVMg) can help children facing severe asthma attacks. The study included 49 pediatric patients who were treated with IVMg after presenting to the emergency department. Some received a placebo, while others were given either 50 or 75 mg/kg of magnesium.
Our analysis showed that higher magnesium levels in the blood were linked to improvements in asthma symptoms, specifically reductions in the Pediatric Respiratory Assessment Measure scores. This suggests that IVMg could be an effective treatment for moderate to severe asthma exacerbations in children.
Interestingly, we noticed that only two out of 31 participants experienced hypotension, showcasing the safety of IVMg, as severe side effects are rare. Moreover, we proposed that a total serum magnesium area under the concentration-time curve greater than 63.1 mg h/L might be a useful target for effective dosing. Further research in larger studies is necessary to confirm these findings, but they indicate that IVMg could serve as a beneficial adjunct treatment for young patients suffering from asthma attacks.
Our analysis showed that higher magnesium levels in the blood were linked to improvements in asthma symptoms, specifically reductions in the Pediatric Respiratory Assessment Measure scores. This suggests that IVMg could be an effective treatment for moderate to severe asthma exacerbations in children.
Interestingly, we noticed that only two out of 31 participants experienced hypotension, showcasing the safety of IVMg, as severe side effects are rare. Moreover, we proposed that a total serum magnesium area under the concentration-time curve greater than 63.1 mg h/L might be a useful target for effective dosing. Further research in larger studies is necessary to confirm these findings, but they indicate that IVMg could serve as a beneficial adjunct treatment for young patients suffering from asthma attacks.
Read More
8
Magnesium sulfate improves asthma outcomes
[Efficacy and safety of magnesium sulfate in the treatment of adult patients with acute severe asthma: a Meta-analysis].
Combination therapy limits assessment
We explored the effectiveness and safety of magnesium sulfate as a treatment for acute severe asthma in adults through a thorough analysis of randomized controlled trials. The studies compared the outcomes of patients receiving conventional asthma treatments with those given additional intravenous magnesium sulfate.
Our findings indicated that magnesium sulfate significantly enhances the total response rate and improves lung function, specifically measured by peak expiratory flow and forced expiratory volume. Importantly, we observed no increase in adverse reactions among those treated with magnesium sulfate.
However, we must emphasize that the overall number and quality of studies included in our analysis were limited. This suggests a need for further high-quality research to confirm these benefits in the future.
Our findings indicated that magnesium sulfate significantly enhances the total response rate and improves lung function, specifically measured by peak expiratory flow and forced expiratory volume. Importantly, we observed no increase in adverse reactions among those treated with magnesium sulfate.
However, we must emphasize that the overall number and quality of studies included in our analysis were limited. This suggests a need for further high-quality research to confirm these benefits in the future.
Read More
7
Magnesium shows limited asthma benefit
Can Intravenous Caffeine Citrate Be Used for Severe Asthma Exacerbation in Children? A Retrospective Comparative Study.
Moderate relevance to magnesium use
We conducted a retrospective cohort study to examine how magnesium sulfate impacts children suffering from severe asthma exacerbations that do not respond to standard treatments like beta2-agonists and steroids. Our research involved a group of young patients who had similar demographic backgrounds and initial health conditions, ensuring a fair evaluation of magnesium's effectiveness compared to intravenous caffeine citrate.
After treatment, we observed that the groups receiving either magnesium or caffeine showed no significant differences in key outcomes. The Paediatric Respiratory Assessment Measure (PRAM) scores, which help assess the severity of asthma symptoms, did not improve markedly between the two. Additionally, there was no notable difference in the length of the pediatric intensive care unit stay or duration of oxygen therapy needed for each group.
While magnesium sulfate has been used in the past for asthma treatment, our findings suggest that it may not offer substantial benefits when used as a rescue option for these difficult cases. This emphasizes the need for more extensive, multicenter studies to confirm these findings and explore the overall effectiveness of magnesium in pediatric asthma management.
After treatment, we observed that the groups receiving either magnesium or caffeine showed no significant differences in key outcomes. The Paediatric Respiratory Assessment Measure (PRAM) scores, which help assess the severity of asthma symptoms, did not improve markedly between the two. Additionally, there was no notable difference in the length of the pediatric intensive care unit stay or duration of oxygen therapy needed for each group.
While magnesium sulfate has been used in the past for asthma treatment, our findings suggest that it may not offer substantial benefits when used as a rescue option for these difficult cases. This emphasizes the need for more extensive, multicenter studies to confirm these findings and explore the overall effectiveness of magnesium in pediatric asthma management.
Read More
Most Useful Reviews
9.5
Dramatic breathing improvement
This product has worked where others failed. For three years, I struggled with asthma and heart issues. After starting magnesium supplements for my heart, I noticed my breathing improved significantly. Once I ran out of this product, my asthma symptoms returned, but they disappeared again upon restarting it. I won't stop using it.
Read More
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 4 Researches
7.5
8
Magnesium sulfate improves asthma outcomes
[Efficacy and safety of magnesium sulfate in the treatment of adult patients with acute severe asthma: a Meta-analysis].
Combination therapy limits assessment
We explored the effectiveness and safety of magnesium sulfate as a treatment for acute severe asthma in adults through a thorough analysis of randomized controlled trials. The studies compared the outcomes of patients receiving conventional asthma treatments with those given additional intravenous magnesium sulfate.
Our findings indicated that magnesium sulfate significantly enhances the total response rate and improves lung function, specifically measured by peak expiratory flow and forced expiratory volume. Importantly, we observed no increase in adverse reactions among those treated with magnesium sulfate.
However, we must emphasize that the overall number and quality of studies included in our analysis were limited. This suggests a need for further high-quality research to confirm these benefits in the future.
Our findings indicated that magnesium sulfate significantly enhances the total response rate and improves lung function, specifically measured by peak expiratory flow and forced expiratory volume. Importantly, we observed no increase in adverse reactions among those treated with magnesium sulfate.
However, we must emphasize that the overall number and quality of studies included in our analysis were limited. This suggests a need for further high-quality research to confirm these benefits in the future.
Read More
8
Magnesium sulfate aids pediatric asthma
Pharmacokinetics and Pharmacodynamics of Intravenous Magnesium Sulfate in Pediatric Acute Asthma Exacerbations.
Highly relevant asthma treatment study
We explored how intravenous magnesium sulfate (IVMg) can help children facing severe asthma attacks. The study included 49 pediatric patients who were treated with IVMg after presenting to the emergency department. Some received a placebo, while others were given either 50 or 75 mg/kg of magnesium.
Our analysis showed that higher magnesium levels in the blood were linked to improvements in asthma symptoms, specifically reductions in the Pediatric Respiratory Assessment Measure scores. This suggests that IVMg could be an effective treatment for moderate to severe asthma exacerbations in children.
Interestingly, we noticed that only two out of 31 participants experienced hypotension, showcasing the safety of IVMg, as severe side effects are rare. Moreover, we proposed that a total serum magnesium area under the concentration-time curve greater than 63.1 mg h/L might be a useful target for effective dosing. Further research in larger studies is necessary to confirm these findings, but they indicate that IVMg could serve as a beneficial adjunct treatment for young patients suffering from asthma attacks.
Our analysis showed that higher magnesium levels in the blood were linked to improvements in asthma symptoms, specifically reductions in the Pediatric Respiratory Assessment Measure scores. This suggests that IVMg could be an effective treatment for moderate to severe asthma exacerbations in children.
Interestingly, we noticed that only two out of 31 participants experienced hypotension, showcasing the safety of IVMg, as severe side effects are rare. Moreover, we proposed that a total serum magnesium area under the concentration-time curve greater than 63.1 mg h/L might be a useful target for effective dosing. Further research in larger studies is necessary to confirm these findings, but they indicate that IVMg could serve as a beneficial adjunct treatment for young patients suffering from asthma attacks.
Read More
7
Magnesium shows limited asthma benefit
Can Intravenous Caffeine Citrate Be Used for Severe Asthma Exacerbation in Children? A Retrospective Comparative Study.
Moderate relevance to magnesium use
We conducted a retrospective cohort study to examine how magnesium sulfate impacts children suffering from severe asthma exacerbations that do not respond to standard treatments like beta2-agonists and steroids. Our research involved a group of young patients who had similar demographic backgrounds and initial health conditions, ensuring a fair evaluation of magnesium's effectiveness compared to intravenous caffeine citrate.
After treatment, we observed that the groups receiving either magnesium or caffeine showed no significant differences in key outcomes. The Paediatric Respiratory Assessment Measure (PRAM) scores, which help assess the severity of asthma symptoms, did not improve markedly between the two. Additionally, there was no notable difference in the length of the pediatric intensive care unit stay or duration of oxygen therapy needed for each group.
While magnesium sulfate has been used in the past for asthma treatment, our findings suggest that it may not offer substantial benefits when used as a rescue option for these difficult cases. This emphasizes the need for more extensive, multicenter studies to confirm these findings and explore the overall effectiveness of magnesium in pediatric asthma management.
After treatment, we observed that the groups receiving either magnesium or caffeine showed no significant differences in key outcomes. The Paediatric Respiratory Assessment Measure (PRAM) scores, which help assess the severity of asthma symptoms, did not improve markedly between the two. Additionally, there was no notable difference in the length of the pediatric intensive care unit stay or duration of oxygen therapy needed for each group.
While magnesium sulfate has been used in the past for asthma treatment, our findings suggest that it may not offer substantial benefits when used as a rescue option for these difficult cases. This emphasizes the need for more extensive, multicenter studies to confirm these findings and explore the overall effectiveness of magnesium in pediatric asthma management.
Read More
7
Magnesium's role in asthma treatment
A Retrospective Review of Children Admitted With Acute Severe Asthma to the Paediatric Intensive Care Unit, Red Cross War Memorial Children's Hospital Between 2009 and 2019.
Limited isolated effect of magnesium
We conducted a comprehensive evaluation of the effects of magnesium treatment on children suffering from acute severe asthma (ASA) who were admitted to the Paediatric Intensive Care Unit (PICU) at the Red Cross War Memorial Children's Hospital over an eleven-year period. During this time, we observed a total of 180 admissions for ASA out of 14,592 PICU visits.
Almost all children received standard treatments, including nebulizations, steroids, and magnesium sulfate, prior to their PICU admission. Among these patients, around 34% had received a salbutamol infusion before being admitted for intensive care. In the PICU, more than 90% of the children received non-invasive respiratory support, showing the severity of their conditions. Notably, while magnesium was used in conjunction with other treatments, the specific isolated effectiveness of magnesium for managing asthma couldn't be clearly assessed.
The findings indicated a steady increase in PICU admissions for ASA throughout the decade. Importantly, no children in the study died, and the average length of stay in PICU was short, typically around one day. While magnesium was part of the treatment regimen, the results didn't provide evidence that it significantly improved outcomes when compared to other treatment options.
Almost all children received standard treatments, including nebulizations, steroids, and magnesium sulfate, prior to their PICU admission. Among these patients, around 34% had received a salbutamol infusion before being admitted for intensive care. In the PICU, more than 90% of the children received non-invasive respiratory support, showing the severity of their conditions. Notably, while magnesium was used in conjunction with other treatments, the specific isolated effectiveness of magnesium for managing asthma couldn't be clearly assessed.
The findings indicated a steady increase in PICU admissions for ASA throughout the decade. Importantly, no children in the study died, and the average length of stay in PICU was short, typically around one day. While magnesium was part of the treatment regimen, the results didn't provide evidence that it significantly improved outcomes when compared to other treatment options.
Read More
User Reviews
USERS' SCORE
Good
Based on 1 Review
8.6
9.5
Dramatic breathing improvement
This product has worked where others failed. For three years, I struggled with asthma and heart issues. After starting magnesium supplements for my heart, I noticed my breathing improved significantly. Once I ran out of this product, my asthma symptoms returned, but they disappeared again upon restarting it. I won't stop using it.
Read More
