Overview
SCIENTIFIC SCORE
Possibly Effective
Based on 16 Researches
7.6
USERS' SCORE
Good
Based on 5 Reviews
8.1
Supplement Facts
Serving Size: 2 Enteric Coated Softgels
Amount Per Serving
%DV
Calories
25
Total Fat
2.5 g
4%†
Cholesterol
<5 mg
2%†
Pure+™ Wild Fish Oil ConcentrateYielding: EPA (eicosapentaenoic acid)DHA (docosahexaenoic acid)
2,000 mg700 mg500 mg
******
Polyphen-Oil™ Olive extract (fruit and leaf)[providing 19.5 mg polyphenols, 5.2 mg hydroxytyrosol/tyrosol, 4.4 mg verbascoside/oleuropein]
300 mg
**
Sesame seed lignan extract
10 mg
**
Top Medical Research Studies
9.5
We analyzed the effects of fish oil lipid emulsion on the prevention of deep vein thrombosis in children with intestinal failure.
In this study, we compared 35 pediatric patients receiving a soy oil lipid emulsion with 35 who received fish oil.
Remarkably, none of the children in the fish oil group experienced blood clots, whereas the soy oil group had ten cases. This suggests that fish oil lipid emulsion may significantly reduce the risk of clots associated with central venous catheters.
In this study, we compared 35 pediatric patients receiving a soy oil lipid emulsion with 35 who received fish oil.
Remarkably, none of the children in the fish oil group experienced blood clots, whereas the soy oil group had ten cases. This suggests that fish oil lipid emulsion may significantly reduce the risk of clots associated with central venous catheters.
9
Omega-3 reduces clot risk post-surgery
We explored the impact of omega-3 fatty acids on blood clot risks in elderly patients recovering from proximal femoral fractures after surgery. In a randomized, double-blind study involving 452 participants, those who received daily supplementation of 1000 mg of omega-3 for 30 days experienced significant reductions in pulmonary embolism and symptomatic deep vein thrombosis compared to those on a placebo. Importantly, these benefits came without an increased risk of bleeding complications.
9
We investigated the impact of FJH-KO, a source of omega-3 fatty acids from Antarctic krill, on thrombosis in a mouse model. By inducing thrombosis using carrageenan, we treated the mice with FJH-KO beforehand.
The results showed that FJH-KO reduced thrombus formation and prolonged bleeding time. It also lowered levels of substances associated with clotting while boosting protective factors. Additionally, in human cells, FJH-KO inhibited the adhesion of immune cells, suggesting its potential as an antithrombotic agent.
The results showed that FJH-KO reduced thrombus formation and prolonged bleeding time. It also lowered levels of substances associated with clotting while boosting protective factors. Additionally, in human cells, FJH-KO inhibited the adhesion of immune cells, suggesting its potential as an antithrombotic agent.
Most Useful Reviews
8
Protects heart health
Absolutely, fish omega cholesterol and DHA are essential for health. It does not have a strong fishy odour. I find it more palatable than other products when I burp. This helps me protect myself from heart blood issues, various diseases, and arthritis. The ingredients are beneficial for hair as well. I have faith in this brand, having just finished this package over the last two months.
7.5
Enhanced skin condition
I regularly take omega and switch manufacturers; I recently tried this supplement. It effectively enhances skin condition, supports brain function, thins the blood, and reduces bad cholesterol levels. I believe the quality is excellent, as this Omega 3 is fish oil rather than a vegetable substitute. The high content of DHA and EPA was a significant factor in my choice, assisting in blood thinning and the removal of bad cholesterol.
7.5
Positive blood test
A doctor noted that my Omega 3 supplementation was responsible for my favourable blood test results in the relevant category. Since changing doctors, he inquired about my supplements, highlighting the benefits related to my blood health.
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 16 Researches
7.6
- All Researches
9.5
We analyzed the effects of fish oil lipid emulsion on the prevention of deep vein thrombosis in children with intestinal failure.
In this study, we compared 35 pediatric patients receiving a soy oil lipid emulsion with 35 who received fish oil.
Remarkably, none of the children in the fish oil group experienced blood clots, whereas the soy oil group had ten cases. This suggests that fish oil lipid emulsion may significantly reduce the risk of clots associated with central venous catheters.
In this study, we compared 35 pediatric patients receiving a soy oil lipid emulsion with 35 who received fish oil.
Remarkably, none of the children in the fish oil group experienced blood clots, whereas the soy oil group had ten cases. This suggests that fish oil lipid emulsion may significantly reduce the risk of clots associated with central venous catheters.
9
We investigated the impact of FJH-KO, a source of omega-3 fatty acids from Antarctic krill, on thrombosis in a mouse model. By inducing thrombosis using carrageenan, we treated the mice with FJH-KO beforehand.
The results showed that FJH-KO reduced thrombus formation and prolonged bleeding time. It also lowered levels of substances associated with clotting while boosting protective factors. Additionally, in human cells, FJH-KO inhibited the adhesion of immune cells, suggesting its potential as an antithrombotic agent.
The results showed that FJH-KO reduced thrombus formation and prolonged bleeding time. It also lowered levels of substances associated with clotting while boosting protective factors. Additionally, in human cells, FJH-KO inhibited the adhesion of immune cells, suggesting its potential as an antithrombotic agent.
9
We investigated how docosahexaenoic acid (DHA) and its derivatives affect platelet activity and blood clotting. Our findings revealed that DHA, along with its oxidized forms, effectively reduced platelet aggregation and activation, particularly in mouse models.
Although DHA showed some benefits, the most significant effects on blood clots came from its oxylipins, specifically 11-HDHA and 14-HDHA. These compounds appeared to inhibit platelet adhesion and thrombus formation through a specific signaling pathway, enhancing the potential for DHA as a treatment for clot-related cardiovascular issues.
Although DHA showed some benefits, the most significant effects on blood clots came from its oxylipins, specifically 11-HDHA and 14-HDHA. These compounds appeared to inhibit platelet adhesion and thrombus formation through a specific signaling pathway, enhancing the potential for DHA as a treatment for clot-related cardiovascular issues.
9
Omega-3 reduces clot risk post-surgery
We explored the impact of omega-3 fatty acids on blood clot risks in elderly patients recovering from proximal femoral fractures after surgery. In a randomized, double-blind study involving 452 participants, those who received daily supplementation of 1000 mg of omega-3 for 30 days experienced significant reductions in pulmonary embolism and symptomatic deep vein thrombosis compared to those on a placebo. Importantly, these benefits came without an increased risk of bleeding complications.
We examined how fish oil, rich in omega-3 polyunsaturated fatty acids (PUFAs), impacts blood clotting in individuals at moderate risk for cardiovascular diseases. In a controlled study with 40 participants, we discovered that fish oil supplementation led to significant changes in circulating extracellular vesicles (EVs), which are linked to clotting processes.
Notably, the fish oil reduced the coagulatory activity of these EVs, suggesting a protective effect against thrombus formation. This finding opens up new avenues for preventing blood clots and managing cardiovascular health.
Notably, the fish oil reduced the coagulatory activity of these EVs, suggesting a protective effect against thrombus formation. This finding opens up new avenues for preventing blood clots and managing cardiovascular health.
User Reviews
USERS' SCORE
Good
Based on 5 Reviews
8.1
- All Reviews
- Positive Reviews
- Negative Reviews
8
Protects heart health
Absolutely, fish omega cholesterol and DHA are essential for health. It does not have a strong fishy odour. I find it more palatable than other products when I burp. This helps me protect myself from heart blood issues, various diseases, and arthritis. The ingredients are beneficial for hair as well. I have faith in this brand, having just finished this package over the last two months.
7.5
Enhanced skin condition
I regularly take omega and switch manufacturers; I recently tried this supplement. It effectively enhances skin condition, supports brain function, thins the blood, and reduces bad cholesterol levels. I believe the quality is excellent, as this Omega 3 is fish oil rather than a vegetable substitute. The high content of DHA and EPA was a significant factor in my choice, assisting in blood thinning and the removal of bad cholesterol.
7.5
Positive blood test
A doctor noted that my Omega 3 supplementation was responsible for my favourable blood test results in the relevant category. Since changing doctors, he inquired about my supplements, highlighting the benefits related to my blood health.
7.5
Effective for cholesterol
1 people found this helpful
Good quality ingredients and value with IFOS certification. I find that the fish oil is suitable for middle-aged individuals to boost HDL cholesterol levels for heart health, as evidenced by my blood test results. It has no fishy taste and is well packaged in a suitably sized box to prevent wastage, although I haven't observed any improvement in my hair.
6
Improves circulation
Omega 3 contributes positively to cholesterol management and enhances blood circulation. I take it for high cholesterol and hyperlipidemia. Taking it during meals mitigates any fishy taste or smell, making it manageable to consume.
Frequently Asked Questions
8
Protects heart health
Absolutely, fish omega cholesterol and DHA are essential for health. It does not have a strong fishy odour. I find it more palatable than other products when I burp. This helps me protect myself from heart blood issues, various diseases, and arthritis. The ingredients are beneficial for hair as well. I have faith in this brand, having just finished this package over the last two months.
6
Improves circulation
Omega 3 contributes positively to cholesterol management and enhances blood circulation. I take it for high cholesterol and hyperlipidemia. Taking it during meals mitigates any fishy taste or smell, making it manageable to consume.
7.5
Positive blood test
A doctor noted that my Omega 3 supplementation was responsible for my favourable blood test results in the relevant category. Since changing doctors, he inquired about my supplements, highlighting the benefits related to my blood health.
7.5
Effective for cholesterol
1 people found this helpful
Good quality ingredients and value with IFOS certification. I find that the fish oil is suitable for middle-aged individuals to boost HDL cholesterol levels for heart health, as evidenced by my blood test results. It has no fishy taste and is well packaged in a suitably sized box to prevent wastage, although I haven't observed any improvement in my hair.
7.5
Enhanced skin condition
I regularly take omega and switch manufacturers; I recently tried this supplement. It effectively enhances skin condition, supports brain function, thins the blood, and reduces bad cholesterol levels. I believe the quality is excellent, as this Omega 3 is fish oil rather than a vegetable substitute. The high content of DHA and EPA was a significant factor in my choice, assisting in blood thinning and the removal of bad cholesterol.
We examined how fish oil, rich in omega-3 polyunsaturated fatty acids (PUFAs), impacts blood clotting in individuals at moderate risk for cardiovascular diseases. In a controlled study with 40 participants, we discovered that fish oil supplementation led to significant changes in circulating extracellular vesicles (EVs), which are linked to clotting processes.
Notably, the fish oil reduced the coagulatory activity of these EVs, suggesting a protective effect against thrombus formation. This finding opens up new avenues for preventing blood clots and managing cardiovascular health.
Notably, the fish oil reduced the coagulatory activity of these EVs, suggesting a protective effect against thrombus formation. This finding opens up new avenues for preventing blood clots and managing cardiovascular health.
7
We investigated the link between omega-3 fatty acids and blood clot markers in patients with atrial fibrillation. By analyzing data from over 2,370 participants, we found that higher levels of total omega-3s were connected to lower levels of D-dimer and beta-thromboglobulin, both indicators of activated coagulation and platelet activity.
This suggests that omega-3s may help reduce blood clot risks. However, while some individual fatty acids showed varied effects, the overall trend points to the potential antithrombotic benefits of these healthy fats.
This suggests that omega-3s may help reduce blood clot risks. However, while some individual fatty acids showed varied effects, the overall trend points to the potential antithrombotic benefits of these healthy fats.
9
We investigated the impact of FJH-KO, a source of omega-3 fatty acids from Antarctic krill, on thrombosis in a mouse model. By inducing thrombosis using carrageenan, we treated the mice with FJH-KO beforehand.
The results showed that FJH-KO reduced thrombus formation and prolonged bleeding time. It also lowered levels of substances associated with clotting while boosting protective factors. Additionally, in human cells, FJH-KO inhibited the adhesion of immune cells, suggesting its potential as an antithrombotic agent.
The results showed that FJH-KO reduced thrombus formation and prolonged bleeding time. It also lowered levels of substances associated with clotting while boosting protective factors. Additionally, in human cells, FJH-KO inhibited the adhesion of immune cells, suggesting its potential as an antithrombotic agent.
9
Omega-3 reduces clot risk post-surgery
We explored the impact of omega-3 fatty acids on blood clot risks in elderly patients recovering from proximal femoral fractures after surgery. In a randomized, double-blind study involving 452 participants, those who received daily supplementation of 1000 mg of omega-3 for 30 days experienced significant reductions in pulmonary embolism and symptomatic deep vein thrombosis compared to those on a placebo. Importantly, these benefits came without an increased risk of bleeding complications.
References
- Bozbas E, Zhou R, Soyama S, Allen-Redpath K, Mitchell JL, et al. Dietary n-3 polyunsaturated fatty acids alter the number, fatty acid profile and coagulatory activity of circulating and platelet-derived extracellular vesicles: a randomized, controlled crossover trial. Am J Clin Nutr. 2024;119:1175. doi:10.1016/j.ajcnut.2024.03.008
- Reiner MF, Bertschi DA, Werlen L, Wiencierz A, Aeschbacher S, et al. Omega-3 Fatty Acids and Markers of Thrombosis in Patients with Atrial Fibrillation. Nutrients. 2024;16. doi:10.3390/nu16020178
- Lee GH, Lee SY, Chae JY, Kim JW, Kim JH, et al. Antarctic Krill Oil from Ameliorates Carrageenan-Induced Thrombosis in a Mouse Model. Int J Mol Sci. 2023;24. doi:10.3390/ijms242417440
- Pawelzik SC, Arnardottir H, Sarajlic P, Mahdi A, Vigor C, et al. Decreased oxidative stress and altered urinary oxylipidome by intravenous omega-3 fatty acid emulsion in a randomized controlled trial of older subjects hospitalized for COVID-19. Free Radic Biol Med. 2023;194:308. doi:10.1016/j.freeradbiomed.2022.12.006
- Yamaguchi A, Stanger L, Freedman CJ, Standley M, Hoang T, et al. DHA 12-LOX-derived oxylipins regulate platelet activation and thrombus formation through a PKA-dependent signaling pathway. J Thromb Haemost. 2021;19:839. doi:10.1111/jth.15184
- Zheng X, Jia R, Li Y, Liu T, Wang Z. Omega-3 fatty acids reduce post-operative risk of deep vein thrombosis and pulmonary embolism after surgery for elderly patients with proximal femoral fractures: a randomized placebo-controlled, double-blind clinical trial. Int Orthop. 2020;44:2089. doi:10.1007/s00264-020-04610-0
- Gaertner S, Auger C, Farooq MA, Pollet B, Khemais-Benkhiat S, et al. Oral Intake of EPA:DHA 6:1 by Middle-Aged Rats for One Week Improves Age-Related Endothelial Dysfunction in Both the Femoral Artery and Vein: Role of Cyclooxygenases. Int J Mol Sci. 2020;21. doi:10.3390/ijms21030920
- Isaksen T, Evensen LH, Brækkan SK, Hansen JB. Dietary Intake of Marine Polyunsaturated n-3 Fatty Acids and Risk of Recurrent Venous Thromboembolism. Thromb Haemost. 2019;119:2053. doi:10.1055/s-0039-1697663
- Carnevale LN, Das A. Novel Anti-inflammatory and Vasodilatory ω-3 Endocannabinoid Epoxide Regioisomers. Adv Exp Med Biol. 2019;1161:219. doi:10.1007/978-3-030-21735-8_17
- Skulas-Ray AC, Wilson PWF, Harris WS, Brinton EA, Kris-Etherton PM, et al. Omega-3 Fatty Acids for the Management of Hypertriglyceridemia: A Science Advisory From the American Heart Association. Circulation. 2019;140:e673. doi:10.1161/CIR.0000000000000709
- Viecelli AK, Polkinghorne KR, Pascoe EM, Paul-Brent PA, Hawley CM, et al. Fish oil and aspirin effects on arteriovenous fistula function: Secondary outcomes of the randomised omega-3 fatty acids (Fish oils) and Aspirin in Vascular access OUtcomes in REnal Disease (FAVOURED) trial. PLoS One. 2019;14:e0213274. doi:10.1371/journal.pone.0213274
- Akintoye E, Sethi P, Harris WS, Thompson PA, Marchioli R, et al. Fish Oil and Perioperative Bleeding. Circ Cardiovasc Qual Outcomes. 2018;11:e004584. doi:10.1161/CIRCOUTCOMES.118.004584
- Spector AA, Kim HY. Emergence of omega-3 fatty acids in biomedical research. Prostaglandins Leukot Essent Fatty Acids. 2019;140:47. doi:10.1016/j.plefa.2018.11.017
- Tam KW, Wu MY, Siddiqui FJ, Chan ES, Zhu Y, et al. Omega-3 fatty acids for dialysis vascular access outcomes in patients with chronic kidney disease. Cochrane Database Syst Rev. 2018;11:CD011353. doi:10.1002/14651858.CD011353.pub2
- Jami MM, Bhardwaj V, Merritt RJ. Intravenous Fish Oil Lipid Emulsion Prevents Catheter-Related Thromboses in Pediatric Patients with Intestinal Failure. J Pediatr. 2018;198:301. doi:10.1016/j.jpeds.2018.03.029
- Adili R, Voigt EM, Bormann JL, Foss KN, Hurley LJ, et al. In vivo modeling of docosahexaenoic acid and eicosapentaenoic acid-mediated inhibition of both platelet function and accumulation in arterial thrombi. Platelets. 2019;30:271. doi:10.1080/09537104.2017.1420154
