'
Life Extension Super Omega-3 Plus EPA/DHA
SCIENTIFIC SCORE
Possibly Effective
Based on 16 Researches
7.1
USERS' SCORE
Good
Based on 9 Reviews
8.5
Supplement Facts
Serving Size: 2 Enteric Coated Softgels
Amount Per Serving
%DV
Calories
25
 
Total Fat
2.5 g
4%†
Cholesterol
<5 mg
2%†
Pure+™ Wild Fish Oil ConcentrateYielding: EPA (eicosapentaenoic acid)DHA (docosahexaenoic acid)
2,000 mg700 mg500 mg
******
Polyphen-Oil™ Olive extract (fruit and leaf)[providing 19.5 mg polyphenols, 5.2 mg hydroxytyrosol/tyrosol, 4.4 mg verbascoside/oleuropein]
300 mg
**
Sesame seed lignan extract
10 mg
**

Top Medical Research Studies

9
Omega-3s' mixed effects on heart health
Update on Omega-3 Polyunsaturated Fatty Acids on Cardiovascular Health.
Moderate relevance in heart research.
We examined the impact of omega-3 fatty acids, often found in fish oil, on heart attack risks, particularly in patients with high triglyceride levels. The studies indicate that while omega-3s can effectively lower triglycerides and reduce certain cardiovascular disease outcomes, including fatal heart attacks, their overall benefit remains debated. Despite extensive research demonstrating some positive outcomes, many experts still question the magnitude of their effects on heart attack prevention. Improved guidance on omega-3 supplementation is still evolving as new evidence emerges.
Read More
8
Omega-3 reduces heart attack risk
Optimal Pair Matching Combined with Machine Learning Predicts a Significant Reduction in Myocardial Infarction Risk in African Americans Following Omega-3 Fatty Acid Supplementation.
High relevance to heart health
We explored the impact of omega-3 fatty acids on heart attack risk, focusing on African Americans. In a study analyzing data from the VITAL trial, we matched African American participants with non-Hispanic White individuals to simulate a randomized controlled trial.

Surprisingly, our findings indicated that omega-3 supplementation significantly decreased heart attack risk in African Americans but showed no benefit for non-Hispanic Whites. This highlights the importance of addressing racial differences in how individuals respond to omega-3 fish oil, urging further research in this area.
Read More
8
Omega-3 fatty acids and heart disease
Associations of circulating fatty acids with incident coronary heart disease: a prospective study of 89,242 individuals in UK Biobank.
Significant relevance among fatty acid studies
We delved into how different types of fatty acids influence the risk of coronary heart disease (CHD) using data from a large study of over 89,000 adults.

Our findings revealed that omega-3 fatty acids seemed to lower the risk of CHD, standing out among other fatty acids. Interestingly, saturated and monounsaturated fats did show a positive link to CHD, but this was largely connected to their effect on triglyceride levels.

Overall, omega-3 fatty acids might offer a protective benefit against heart disease.
Read More

Most Useful Reviews

9.5
Supports heart health
This excellent supplement has greatly supported my heart health and improved my cognitive function while reducing inflammation. The results have been remarkable, and I plan to continue using it. I've noticed better heart function and an overall sense of alertness, along with improved focus after a few weeks of use, as well as a reduction in mild fatigue post-exercise.
Read More
8.3
Supports overall health
This omega is of exceptional quality. The ingredients truly shine. It benefits my entire body, supports heart function, restores cholesterol levels, alleviates inflammation, and improves joint health, hair, skin, and nails. It has a neutral taste and is easy to ingest, contributing significantly to cognitive health. I wholeheartedly recommend it.
Read More
8.8
Reduced palpitations
My palpitations seem to have decreased significantly. Indefinite complaints and headaches have also diminished. While this might not be the sole reason, fish is expensive, and the hassle of cooking and cleaning is tedious, so I find supplements much more convenient, and that's why I continue taking them.
Read More

Medical Researches

SCIENTIFIC SCORE
Possibly Effective
Based on 16 Researches
7.1
  • All Researches
9
Omega-3s' mixed effects on heart health
Update on Omega-3 Polyunsaturated Fatty Acids on Cardiovascular Health.
Moderate relevance in heart research.
We examined the impact of omega-3 fatty acids, often found in fish oil, on heart attack risks, particularly in patients with high triglyceride levels. The studies indicate that while omega-3s can effectively lower triglycerides and reduce certain cardiovascular disease outcomes, including fatal heart attacks, their overall benefit remains debated. Despite extensive research demonstrating some positive outcomes, many experts still question the magnitude of their effects on heart attack prevention. Improved guidance on omega-3 supplementation is still evolving as new evidence emerges.
Read More
9
Omega-3 benefits for smokers' heart health
Potential effects of icosapent ethyl on cardiovascular outcomes in cigarette smokers: REDUCE-IT smoking.
Significant cardiovascular outcomes observed
We explored whether icosapent ethyl (IPE), a refined omega-3 fatty acid, could lower heart attack risk among cigarette smokers. In the REDUCE-IT trial, over 8,000 statin-treated patients were randomly assigned to receive either IPE or a placebo for nearly five years.

Our findings showed that IPE significantly reduced cardiovascular events by 25%, especially for current and former smokers. Participants using IPE experienced heart attack rates similar to non-smokers, suggesting that IPE may help lessen cardiovascular risks associated with smoking.
Read More
8
Omega-3 reduces heart attack risk
Cardiovascular Outcomes With Icosapent Ethyl by Baseline Low-Density Lipoprotein Cholesterol: A Secondary Analysis of the REDUCE-IT Randomized Trial.
Study shows significant treatment benefits
We investigated whether icosapent ethyl is beneficial in reducing heart attack rates among patients with well-managed low-density lipoprotein cholesterol (LDL-C).

Analyzing data from the REDUCE-IT trial, we found that this treatment significantly lowered cardiovascular complications in statin-treated patients, regardless of their baseline LDL-C levels.

Specifically, it proved effective for those with optimal LDL-C control, showing that even patients with very low cholesterol can benefit from this omega-3 treatment in preventing serious heart events.
Read More
8
Omega-3 reduces heart attack risk
Optimal Pair Matching Combined with Machine Learning Predicts a Significant Reduction in Myocardial Infarction Risk in African Americans Following Omega-3 Fatty Acid Supplementation.
High relevance to heart health
We explored the impact of omega-3 fatty acids on heart attack risk, focusing on African Americans. In a study analyzing data from the VITAL trial, we matched African American participants with non-Hispanic White individuals to simulate a randomized controlled trial.

Surprisingly, our findings indicated that omega-3 supplementation significantly decreased heart attack risk in African Americans but showed no benefit for non-Hispanic Whites. This highlights the importance of addressing racial differences in how individuals respond to omega-3 fish oil, urging further research in this area.
Read More
8
Omega-3 improves heart attack outcomes
Effects of icosapent ethyl according to baseline residual risk in patients with atherosclerotic cardiovascular disease: results from REDUCE-IT.
High relevance for cardiovascular health.
We observed that icosapent ethyl, a type of omega-3 fish oil, plays a significant role in reducing heart attack risk among patients with atherosclerotic cardiovascular disease (ASCVD). In a study involving almost 5,800 participants, those taking icosapent ethyl experienced lower rates of major adverse cardiovascular events (MACE) compared to those on placebo.

The treatment showed effectiveness across all levels of cardiovascular risk, particularly benefiting those at higher risk. Overall, this suggests that incorporating icosapent ethyl could be an important option for managing heart attack risks.
Read More

User Reviews

USERS' SCORE
Good
Based on 9 Reviews
8.5
  • All Reviews
  • Positive Reviews
  • Negative Reviews
9.5
Supports heart health
This excellent supplement has greatly supported my heart health and improved my cognitive function while reducing inflammation. The results have been remarkable, and I plan to continue using it. I've noticed better heart function and an overall sense of alertness, along with improved focus after a few weeks of use, as well as a reduction in mild fatigue post-exercise.
Read More
8.3
Supports overall health
This omega is of exceptional quality. The ingredients truly shine. It benefits my entire body, supports heart function, restores cholesterol levels, alleviates inflammation, and improves joint health, hair, skin, and nails. It has a neutral taste and is easy to ingest, contributing significantly to cognitive health. I wholeheartedly recommend it.
Read More
8.8
Reduced palpitations
My palpitations seem to have decreased significantly. Indefinite complaints and headaches have also diminished. While this might not be the sole reason, fish is expensive, and the hassle of cooking and cleaning is tedious, so I find supplements much more convenient, and that's why I continue taking them.
Read More
8.8
Complex supplement
This omega is sourced from wild fish, which is significant, and it carries certificates that guarantee its purity. It also contains polyphenols from olive leaves and fruits, which support the cardiovascular and circulatory systems alongside omega-3. Together, they form a valuable complex for heart and blood vessel health. Given the price per share, it's not much more than standard options.
Read More
8.8
Lowers cholesterol
Omega is vital for maintaining health. This isn't my first purchase of this omega; it's beneficial for heart health and lowers cholesterol, particularly for those who don't consume fish. I love the quality of this brand.
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