Overview

SCIENTIFIC SCORE
Moderately Effective
Based on 14 Researches
8.5
USERS' SCORE
Good
Based on 2 Reviews
8.6
Supplement Facts
Serving Size:  1 Vegetarian Capsule
Amount Per Serving
%DV
Vitamin C (from ascorbic acid, camu-camu berry extract)
30 mg
33%
Quercetin (as quercetin dihydrate)
250 mg
**
Optimized Food Blend[onion (bulb) (extracts), bitter orange bioflavonoids (peel and fruit), apple (fruit)
220 mg
**
Camu-camu extract (wildcrafted berry)
50 mg
**

Top Medical Research Studies

9
Quercetin reduces diarrhea in piglets
This study strategically divided 48 weaned piglets into four groups to evaluate how quercetin impacts diarrhea and growth. We noticed that piglets receiving higher doses of quercetin (500 and 750 mg/kg) had significantly fewer instances of diarrhea and an improved feed-to-gain ratio.

Additionally, quercetin improved the diversity of gut bacteria and regulated key inflammatory markers, suggesting it helps balance gut health. This shows promise for using quercetin as a means to reduce diarrhea and enhance growth performance in weaned piglets.
Read More
We aimed to explore the effectiveness of quercetin, a key polyphenol found in Psidium cattleianum Sabine, for treating diarrhea. Through various tests, including both in vivo and in vitro models, we observed that a defatted aqueous methanol extract (DAME) of the plant showed significant promise. Higher doses delayed diarrhea onset and reduced gastrointestinal transit, showcasing an impressive inhibition effect.

However, while quercetin and related compounds demonstrated binding to crucial receptors, further studies and clinical trials are needed to fully confirm its potential as a reliable treatment for diarrhea.
Read More
9
Quercetin shows significant antidiarrheal effects
We evaluated the antidiarrheal effects of leaf extract from an Ethiopian plant, known for its traditional medicinal use. Through a series of tests in mice, we found that the leaf extract significantly reduced diarrhea onset, fecal weight, and the frequency of defecation. Among the components tested, quercetin, extracted and identified from the plant, showed strong antidiarrheal activity as well. This supports the idea that quercetin plays a key role in alleviating diarrhea, contributing positively to the plant's traditional use in medicinal practices.
Read More

Most Useful Reviews

9
No diarrhea occurred
This product effectively combats viral infections and aids sleep. Previously, I bought natural Sophora japonica quercetin, which was too cold and caused diarrhoea. However, after switching to this product, it no longer led to diarrhoea. Additionally, my sleep quality has improved significantly, and unlike GlyNAC, there is no development of tolerance with this product.
Read More
9
No more diarrhea
Very good antioxidant; I won't experience diarrhoea even after consuming it. I feel as though it's effective.
Read More

Medical Researches

SCIENTIFIC SCORE
Moderately Effective
Based on 14 Researches
8.5
  • All Researches
We aimed to explore the effectiveness of quercetin, a key polyphenol found in Psidium cattleianum Sabine, for treating diarrhea. Through various tests, including both in vivo and in vitro models, we observed that a defatted aqueous methanol extract (DAME) of the plant showed significant promise. Higher doses delayed diarrhea onset and reduced gastrointestinal transit, showcasing an impressive inhibition effect.

However, while quercetin and related compounds demonstrated binding to crucial receptors, further studies and clinical trials are needed to fully confirm its potential as a reliable treatment for diarrhea.
Read More
9
Quercetin reduces diarrhea in piglets
This study strategically divided 48 weaned piglets into four groups to evaluate how quercetin impacts diarrhea and growth. We noticed that piglets receiving higher doses of quercetin (500 and 750 mg/kg) had significantly fewer instances of diarrhea and an improved feed-to-gain ratio.

Additionally, quercetin improved the diversity of gut bacteria and regulated key inflammatory markers, suggesting it helps balance gut health. This shows promise for using quercetin as a means to reduce diarrhea and enhance growth performance in weaned piglets.
Read More
9
Quercetin shows significant antidiarrheal effects
We evaluated the antidiarrheal effects of leaf extract from an Ethiopian plant, known for its traditional medicinal use. Through a series of tests in mice, we found that the leaf extract significantly reduced diarrhea onset, fecal weight, and the frequency of defecation. Among the components tested, quercetin, extracted and identified from the plant, showed strong antidiarrheal activity as well. This supports the idea that quercetin plays a key role in alleviating diarrhea, contributing positively to the plant's traditional use in medicinal practices.
Read More
We investigated how quercetin, derived from a well-known medicinal plant, may help treat diarrhea. The research involved both laboratory tests and molecular analysis to assess its effects.

We found that quercetin and other compounds significantly reduced diarrhea in tests, especially in higher doses. The results indicated that the extracts exhibited effective antidiarrheal properties.

However, the the specific benefits of quercetin, compared to other components, were not clearly distinguished. This study supports the traditional use of these natural remedies for digestive issues.
Read More
We investigated the antidiarrheal properties of extracts from two plant species, focusing on their quercetin content. In a controlled study using a castor oil-induced diarrhea model, we found that both extracts significantly delayed the onset of diarrhea and reduced intestinal fluid volume compared to the control group.

While both plant extracts demonstrated effectiveness, the one with higher quercetin levels showed even stronger results. The findings suggest that quercetin, along with other compounds, may play an important role in managing diarrhea.
Read More

User Reviews

USERS' SCORE
Good
Based on 2 Reviews
8.6
  • All Reviews
  • Positive Reviews
  • Negative Reviews
9
No diarrhea occurred
This product effectively combats viral infections and aids sleep. Previously, I bought natural Sophora japonica quercetin, which was too cold and caused diarrhoea. However, after switching to this product, it no longer led to diarrhoea. Additionally, my sleep quality has improved significantly, and unlike GlyNAC, there is no development of tolerance with this product.
Read More
9
No more diarrhea
Very good antioxidant; I won't experience diarrhoea even after consuming it. I feel as though it's effective.
Read More

Frequently Asked Questions

No FAQs are available for this product and symptom.

References

  1. El-Deeb EM, Elsayed HE, Khazaal MT, El-Sayed EK, Ahmed AA, et al. Comprehensive assessment of the antidiarrheal properties of polyphenols from Psidium cattleianum Sabine's aerial parts. J Ethnopharmacol. 2025;346:119670. 10.1016/j.jep.2025.119670
  2. Mao Y, Yang Q, Liu J, Fu Y, Zhou S, et al. Quercetin Increases Growth Performance and Decreases Incidence of Diarrhea and Mechanism of Action in Weaned Piglets. Oxid Med Cell Longev. 2024;2024:5632260. 10.1155/2024/5632260
  3. Mogose B, Bisrat D, Asres K. Antidiarrheal Potential of the Leaf Extract of (Loes.) Sebsebe and Its Major Compound. J Trop Med. 2024;2024:5922487. 10.1155/2024/5922487
  4. Feng Y, Yi H, Zheng X, Liu X, Gong T, et al. Quercetin inhibition of porcine intestinal alpha coronavirus in vitro and in vivo. BMC Vet Res. 2024;20:134. 10.1186/s12917-024-03984-2
  5. Gong T, Wu D, Feng Y, Liu X, Gao Q, et al. Inhibitory effects of quercetin on porcine epidemic diarrhea virus in vitro and in vivo. Virology. 2024;589:109923. 10.1016/j.virol.2023.109923
  6. Ahmad I, Alotaibi BS, Malak N, Asad F, Ullah B, et al. Antidiarrheal Potential of : In Vivo and In Silico Approaches. Pharmaceuticals (Basel). 2023;16. 10.3390/ph16040489
  7. Mady MS, Ibrahim RR, El-Sayed EK, El-Shazly M, Chen LY, et al. UHPLC-MS profiles and antidiarrheal activity of münchh. and L. employing technique. Front Pharmacol. 2023;14:1120146. 10.3389/fphar.2023.1120146
  8. Wahid M, Saqib F, Akhtar S, Ali A, Tallei TE, et al. Mechanistic insights of Cucumis melo L. seeds for gastrointestinal muscle spasms through calcium signaling pathway-related gene regulation networks in WGCNA and in vitro, in vivo studies. Comput Biol Med. 2023;155:106596. 10.1016/j.compbiomed.2023.106596
  9. Banerjee S, Sarkar R, Mukherjee A, Miyoshi SI, Kitahara K, et al. Quercetin, a flavonoid, combats rotavirus infection by deactivating rotavirus-induced pro-survival NF-κB pathway. Front Microbiol. 2022;13:951716. 10.3389/fmicb.2022.951716
  10. Saqib F, Al-Huqail AA, Asma M, Chicea L, Hogea M, et al. Dose-dependent Spasmolytic, Bronchodilator, and Hypotensive Activities of L. Dose Response. 2022;20:15593258221079592. 10.1177/15593258221079592
  11. Xu B, Qin W, Xu Y, Yang W, Chen Y, et al. Dietary Quercetin Supplementation Attenuates Diarrhea and Intestinal Damage by Regulating Gut Microbiota in Weanling Piglets. Oxid Med Cell Longev. 2021;2021:6221012. 10.1155/2021/6221012
  12. Zhang Y, Yu F, Hao J, Nsabimana E, Wei Y, et al. Study on the Effective Material Basis and Mechanism of Traditional Chinese Medicine Prescription (QJC) Against Stress Diarrhea in Mice. Front Vet Sci. 2021;8:724491. 10.3389/fvets.2021.724491
  13. Mady MS, Elsayed HE, El-Sayed EK, Hussein AA, Ebrahim HY, et al. Polyphenolic profile and ethno pharmacological activities of Callistemonsubulatus (Cheel) Craven leaves cultivated in Egypt. J Ethnopharmacol. 2022;284:114698. 10.1016/j.jep.2021.114698
  14. Alam MM, Emon NU, Alam S, Rudra S, Akhter N, et al. Assessment of pharmacological activities of Lygodium microphyllum Cav. leaves in the management of pain, inflammation, pyrexia, diarrhea, and helminths: In vivo, in vitro and in silico approaches. Biomed Pharmacother. 2021;139:111644. 10.1016/j.biopha.2021.111644
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