Promising but requires further studyComprehensive assessment of the antidiarrheal properties of polyphenols from Psidium cattleianum Sabine's aerial parts.
Relevant for diarrhea treatment research.
We aimed to explore the effectiveness of quercetin, a key polyphenol found in Psidium cattleianum Sabine, for treating diarrhea. Through various tests, including both in vivo and in vitro models, we observed that a defatted aqueous methanol extract (DAME) of the plant showed significant promise. Higher doses delayed diarrhea onset and reduced gastrointestinal transit, showcasing an impressive inhibition effect.
However, while quercetin and related compounds demonstrated binding to crucial receptors, further studies and clinical trials are needed to fully confirm its potential as a reliable treatment for diarrhea.
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Quercetin reduces diarrhea in pigletsQuercetin Increases Growth Performance and Decreases Incidence of Diarrhea and Mechanism of Action in Weaned Piglets.
High relevance for animal health
This study strategically divided 48 weaned piglets into four groups to evaluate how quercetin impacts diarrhea and growth. We noticed that piglets receiving higher doses of quercetin (500 and 750 mg/kg) had significantly fewer instances of diarrhea and an improved feed-to-gain ratio.
Additionally, quercetin improved the diversity of gut bacteria and regulated key inflammatory markers, suggesting it helps balance gut health. This shows promise for using quercetin as a means to reduce diarrhea and enhance growth performance in weaned piglets.
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We evaluated the antidiarrheal effects of leaf extract from an Ethiopian plant, known for its traditional medicinal use. Through a series of tests in mice, we found that the leaf extract significantly reduced diarrhea onset, fecal weight, and the frequency of defecation. Among the components tested, quercetin, extracted and identified from the plant, showed strong antidiarrheal activity as well. This supports the idea that quercetin plays a key role in alleviating diarrhea, contributing positively to the plant's traditional use in medicinal practices.
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We investigated how quercetin, derived from a well-known medicinal plant, may help treat diarrhea. The research involved both laboratory tests and molecular analysis to assess its effects.
We found that quercetin and other compounds significantly reduced diarrhea in tests, especially in higher doses. The results indicated that the extracts exhibited effective antidiarrheal properties.
However, the the specific benefits of quercetin, compared to other components, were not clearly distinguished. This study supports the traditional use of these natural remedies for digestive issues.
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We investigated the antidiarrheal properties of extracts from two plant species, focusing on their quercetin content. In a controlled study using a castor oil-induced diarrhea model, we found that both extracts significantly delayed the onset of diarrhea and reduced intestinal fluid volume compared to the control group.
While both plant extracts demonstrated effectiveness, the one with higher quercetin levels showed even stronger results. The findings suggest that quercetin, along with other compounds, may play an important role in managing diarrhea.
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