We investigated how zinc, delivered through epipharyngeal abrasive therapy (EAT), might impact the expression of a key molecule known as Cav1.2, which plays a crucial role in allowing the influenza A virus to enter cells. The study included two groups of patients: one group that received EAT, which involved scratching the epipharyngeal mucosa with a zinc chloride-treated swab, and another group that did not receive this treatment.
By analyzing tissue samples, we observed that the levels of Cav1.2 were significantly lower in the EAT-treated patients compared to those who were not treated. In fact, the expression of Cav1.2 in the patients who underwent EAT was measured to be 4.19 times lower than in the non-treated group. This suggests that the squamous metaplasia induced by EAT might help reduce the entry of the influenza virus by down-regulating this key protein.
Our findings indicate that EAT, through its zinc content, could serve as a simple and effective method to potentially prevent influenza infection by limiting the virus's ability to enter cells.
Read More
9
Impact of Zinc on Vaccine Response
Modulation of T-Cell-Dependent Humoral Immune Response to Influenza Vaccine by Multiple Antioxidant/Immunomodulatory Micronutrient Supplementation.
We examined how combining zinc with other essential micronutrients could impact the immune response to an influenza vaccine. Our study found that this combination, including vitamins C and D, selenium, manganese, and N-acetyl cysteine, led to increased levels of protective antibodies after vaccinations in mice.
Notably, the supplementation improved not just the overall antibody response but also boosted specific immune responses vital for effective virus clearance. We observed a rise in specific types of immune cells, such as germinal center B cells and helper T cells, which are crucial in fighting off infections. Moreover, this combination influenced a greater differentiation of T helper cells, enhancing the production of important cytokines.
While our findings highlighted the beneficial effects of this micronutrient combination on immunity, it is also important to note that the study evaluated these effects in a controlled setting involving multiple micronutrients. Although zinc is included, its isolated impact on the immune response to influenza was less discernible due to the mixture of supplements tested. Overall, our research lays the groundwork for future studies aimed at improving vaccination responses through dietary adjustments.
Read More
Most Useful Reviews
9
Prevention recommendation
4 people found this helpful
The leader in the prevention and treatment of influenza and ARVI! Zinc, paired with vitamin D, is essential for cold prevention. My family takes zinc twice a year for two months as a prophylactic measure. This product is effective; the brand is commendable. I wholeheartedly recommend it.
Read More
9
Well tolerated
It is well tolerated with no side effects, even though zinc can sometimes cause gastrointestinal issues. I take it during influenza season to support my immunity in autumn and spring. Since I started this, I haven't fallen ill. I highly recommend it.
Read More
9
Immunity support
Zinc is a crucial mineral not naturally produced by our bodies, so we must obtain it through diet or supplements. It enhances the immune system and has a direct antiviral effect. Zinc is included in treatment regimens for various viral infections like ARVI, influenza, and others. I take half a capsule daily for a month and highly recommend this product!
We examined how combining zinc with other essential micronutrients could impact the immune response to an influenza vaccine. Our study found that this combination, including vitamins C and D, selenium, manganese, and N-acetyl cysteine, led to increased levels of protective antibodies after vaccinations in mice.
Notably, the supplementation improved not just the overall antibody response but also boosted specific immune responses vital for effective virus clearance. We observed a rise in specific types of immune cells, such as germinal center B cells and helper T cells, which are crucial in fighting off infections. Moreover, this combination influenced a greater differentiation of T helper cells, enhancing the production of important cytokines.
While our findings highlighted the beneficial effects of this micronutrient combination on immunity, it is also important to note that the study evaluated these effects in a controlled setting involving multiple micronutrients. Although zinc is included, its isolated impact on the immune response to influenza was less discernible due to the mixture of supplements tested. Overall, our research lays the groundwork for future studies aimed at improving vaccination responses through dietary adjustments.
Read More
8
Zinc may prevent influenza entry
Epipharyngeal Abrasive Therapy Down-regulates the Expression of Cav1.2: A Key Molecule in Influenza Virus Entry.
We investigated how zinc, delivered through epipharyngeal abrasive therapy (EAT), might impact the expression of a key molecule known as Cav1.2, which plays a crucial role in allowing the influenza A virus to enter cells. The study included two groups of patients: one group that received EAT, which involved scratching the epipharyngeal mucosa with a zinc chloride-treated swab, and another group that did not receive this treatment.
By analyzing tissue samples, we observed that the levels of Cav1.2 were significantly lower in the EAT-treated patients compared to those who were not treated. In fact, the expression of Cav1.2 in the patients who underwent EAT was measured to be 4.19 times lower than in the non-treated group. This suggests that the squamous metaplasia induced by EAT might help reduce the entry of the influenza virus by down-regulating this key protein.
Our findings indicate that EAT, through its zinc content, could serve as a simple and effective method to potentially prevent influenza infection by limiting the virus's ability to enter cells.
Read More
User Reviews
USERS' SCORE
Good
Based on 14 Reviews
8.3
All Reviews
Positive Reviews
Negative Reviews
9
Prevention recommendation
4 people found this helpful
The leader in the prevention and treatment of influenza and ARVI! Zinc, paired with vitamin D, is essential for cold prevention. My family takes zinc twice a year for two months as a prophylactic measure. This product is effective; the brand is commendable. I wholeheartedly recommend it.
Read More
9
Well tolerated
It is well tolerated with no side effects, even though zinc can sometimes cause gastrointestinal issues. I take it during influenza season to support my immunity in autumn and spring. Since I started this, I haven't fallen ill. I highly recommend it.
Read More
9
Immunity support
Zinc is a crucial mineral not naturally produced by our bodies, so we must obtain it through diet or supplements. It enhances the immune system and has a direct antiviral effect. Zinc is included in treatment regimens for various viral infections like ARVI, influenza, and others. I take half a capsule daily for a month and highly recommend this product!
Read More
9
Highly recommended for influenza
The zinc dosage is effective at 50 mg for prophylaxis, but for treating influenza, two capsules daily are perfect! The citrate and zinc monomethionine forms offer great bioavailability, especially during influenza and the SARS season. A must-have for any medicine cabinet. I highly recommend it!
Read More
9
Rapid relief from influenza
We always keep this effective zinc in the house at a large dosage of 50 mg to combat ARVI at the first signs. Along with zinc, we take large doses of vitamin D (up to 20,000 IU) and C (500 mg every hour or two). Influenza symptoms diminish significantly within 1-2 days.
Influenza, commonly referred to as the flu, is a highly contagious viral infection that primarily affects the respiratory system. Caused by influenza viruses, it can lead to mild to severe illness and can result in hospitalization or even death, particularly in vulnerable populations such as the elderly, young children, and individuals with certain health conditions. Symptoms typically include fever, chills, cough, sore throat, body aches, headaches, and fatigue. It's important to note that while many people refer to common colds as the flu, the flu is generally more severe and lasts longer.
Preventing influenza is possible through vaccination, which is recommended annually as the viruses can change from year to year. Other preventive measures include practicing good hygiene, such as regular hand washing and avoiding close contact with infected individuals. If someone does contract the flu, antiviral medications may be prescribed by a healthcare provider, particularly if the treatment begins within the first few days of illness. Understanding the nature of influenza and the importance of preventive measures can help individuals protect themselves and their communities during flu season.
Zinc is a versatile metal known for its various applications in industry and health. It is a bluish-white metallic element represented by the symbol Zn and atomic number 30 on the periodic table. Zinc is primarily used for galvanizing steel to prevent rusting, in the manufacturing of alloys, and as a component in batteries. Additionally, zinc plays a crucial role in biological processes, making it an essential trace element in the human diet. It is involved in immune function, protein synthesis, wound healing, and DNA synthesis, highlighting its importance in maintaining overall health and well-being.
Zinc may play a role in supporting the immune system, which could potentially be beneficial during an influenza infection. Some studies suggest that zinc supplementation might reduce the duration and severity of cold symptoms, and while the research is not as conclusive for influenza specifically, the mineral is known to be involved in various immune functions. It is thought that zinc helps in battling viruses and bacteria, so ensuring adequate zinc levels may help your body respond more effectively to infections, including the flu.
However, it's important to note that while zinc can support immune function, it should not be seen as a replacement for the flu vaccine or standard medical treatment. Furthermore, excessive zinc intake can lead to adverse effects, so it's crucial to discuss any supplementation with a healthcare professional. If you're considering using zinc as part of your influenza management strategy, consult your doctor for personalized advice and appropriate dosages.
According to user reviews, many individuals report experiencing significant relief from influenza symptoms within 1 to 2 days of beginning treatment with zinc supplements. For instance, one user mentioned that they observed a notable decrease in influenza symptoms in just 1-2 days after starting zinc, particularly when paired with high doses of vitamin D and C Read Review. While the exact timing for results may vary, several other users emphasized taking zinc as a preventive measure during influenza season suggests that consistent use over a month can enhance your immune response, ultimately reducing the chances of falling ill Read Review.
More specifically, some users advocate for taking zinc in higher doses, particularly when symptoms first appear, as this seems to optimize effectiveness against viral infections like influenza Read Review. Overall, while individual experiences may vary, the general consensus among users is that taking zinc supplements regularly during the influenza season is beneficial and can lead to quicker recovery times.
The scientific research reviewed indicates potential benefits of zinc as a supplement for influenza prevention and immune response enhancement. A study demonstrated that combining zinc with other essential micronutrients increased protective antibody levels following influenza vaccination in mice, suggesting a robust immune response due to this combination [1]. This research points to the importance of micronutrients in bolstering immunity, although the direct impact of zinc alone on influenza was less clear due to the mixed nature of the supplements evaluated.
Additionally, another study highlighted a novel approach using zinc through epipharyngeal abrasive therapy (EAT), which significantly reduced the expression of Cav1.2—a crucial molecule that facilitates the entry of the influenza virus into cells. This finding indicates that EAT might serve as an effective method to limit influenza infection by down-regulating this key protein involved in viral entry [2]. Overall, while there is compelling evidence supporting the role of zinc in influenza-related immune responses, it is essential to consider that these studies often incorporate multiple nutrients or treatment methods.
Based on user reviews, many individuals report notable improvements in their symptoms when taking zinc supplements, particularly during the influenza season. Several users have shared their experiences of increased immunity and a significant reduction in the severity and duration of illness. For instance, one user mentioned that influenza symptoms diminished significantly within just 1-2 days after starting zinc, especially when paired with high doses of vitamins D and C Read Review. Another user noted that since incorporating zinc into their regimen during the influenza season, they haven’t fallen ill, attributing this consistent use to their strengthened immune system Read Review.
Additionally, numerous users emphasize the importance of dosage. Some advocate for higher doses when symptoms first appear, noting that this approach seems particularly effective against viral infections Read Review. While results can vary from person to person, the collective feedback suggests that regular use of zinc can contribute to better defense against respiratory infections, making it a popular choice during colder months Read Review. Overall, users seem to agree on the beneficial effects of zinc in augmenting one’s immune response against influenza.
Users report a strong endorsement of combining zinc supplements with vitamins D and C to effectively combat influenza. Many reviews highlight that taking zinc in higher doses, particularly when symptoms emerge, can enhance recovery. One user noted that they typically take 50 mg of zinc alongside substantial doses of vitamin D (up to 20,000 IU) and vitamin C (500 mg every hour or two), resulting in a significant reduction in flu symptoms within 1-2 days Read Review. This synergy is credited with bolstering immune defenses, making it a popular choice among users during influenza season Read Review.
In addition to its role as a standalone treatment, zinc is often spoken of as part of a broader regimen to prevent influenza. One user remarked that consistent supplementation during the colder months has kept them illness-free, attributing this success to their preventive measures, which often include zinc Read Review. The consensus is clear: when taken alongside other immune-supportive vitamins, zinc not only aids in treating symptoms but also plays a crucial role in prevention strategies for respiratory infections like influenza Read Review.
Users report varying doses of zinc for treating influenza, with many agreeing on higher dosages for effectiveness. One user found that taking two capsules daily was ideal for treating influenza, whereas another suggested a prophylactic dosage of 50 mg for prevention purposes, noting its high bioavailability when paired with appropriate forms like zinc citrate and zinc monomethionine Read Review. Others advocate for relatively large doses, such as 50 mg, to combat early signs of illness, while simultaneously recommending the addition of vitamin D and C for comprehensive immunity support Read Review.
Additionally, some users highlighted their success in preventing illness through prophylactic zinc use, taking doses either daily or in response to the onset of symptoms Read Review. Overall, while there is no consensus on a single 'right' dose, a common recommendation appears to be at least 50 mg for prevention and higher doses for those actively combating influenza, as noted by multiple reviewers Read Review.
9
Rapid relief from influenza
We always keep this effective zinc in the house at a large dosage of 50 mg to combat ARVI at the first signs. Along with zinc, we take large doses of vitamin D (up to 20,000 IU) and C (500 mg every hour or two). Influenza symptoms diminish significantly within 1-2 days.
9
Immunity support
Zinc is a crucial mineral not naturally produced by our bodies, so we must obtain it through diet or supplements. It enhances the immune system and has a direct antiviral effect. Zinc is included in treatment regimens for various viral infections like ARVI, influenza, and others. I take half a capsule daily for a month and highly recommend this product!
9
Highly recommended for influenza
The zinc dosage is effective at 50 mg for prophylaxis, but for treating influenza, two capsules daily are perfect! The citrate and zinc monomethionine forms offer great bioavailability, especially during influenza and the SARS season. A must-have for any medicine cabinet. I highly recommend it!
9
Well tolerated
It is well tolerated with no side effects, even though zinc can sometimes cause gastrointestinal issues. I take it during influenza season to support my immunity in autumn and spring. Since I started this, I haven't fallen ill. I highly recommend it.
9
Prevention recommendation
4 people found this helpful
The leader in the prevention and treatment of influenza and ARVI! Zinc, paired with vitamin D, is essential for cold prevention. My family takes zinc twice a year for two months as a prophylactic measure. This product is effective; the brand is commendable. I wholeheartedly recommend it.
9
Good for prevention
The dosage is excellent for both prevention and treatment during the influenza season!
9
Impact of Zinc on Vaccine Response
Modulation of T-Cell-Dependent Humoral Immune Response to Influenza Vaccine by Multiple Antioxidant/Immunomodulatory Micronutrient Supplementation.
We examined how combining zinc with other essential micronutrients could impact the immune response to an influenza vaccine. Our study found that this combination, including vitamins C and D, selenium, manganese, and N-acetyl cysteine, led to increased levels of protective antibodies after vaccinations in mice.
Notably, the supplementation improved not just the overall antibody response but also boosted specific immune responses vital for effective virus clearance. We observed a rise in specific types of immune cells, such as germinal center B cells and helper T cells, which are crucial in fighting off infections. Moreover, this combination influenced a greater differentiation of T helper cells, enhancing the production of important cytokines.
While our findings highlighted the beneficial effects of this micronutrient combination on immunity, it is also important to note that the study evaluated these effects in a controlled setting involving multiple micronutrients. Although zinc is included, its isolated impact on the immune response to influenza was less discernible due to the mixture of supplements tested. Overall, our research lays the groundwork for future studies aimed at improving vaccination responses through dietary adjustments.
8
Zinc may prevent influenza entry
Epipharyngeal Abrasive Therapy Down-regulates the Expression of Cav1.2: A Key Molecule in Influenza Virus Entry.
We investigated how zinc, delivered through epipharyngeal abrasive therapy (EAT), might impact the expression of a key molecule known as Cav1.2, which plays a crucial role in allowing the influenza A virus to enter cells. The study included two groups of patients: one group that received EAT, which involved scratching the epipharyngeal mucosa with a zinc chloride-treated swab, and another group that did not receive this treatment.
By analyzing tissue samples, we observed that the levels of Cav1.2 were significantly lower in the EAT-treated patients compared to those who were not treated. In fact, the expression of Cav1.2 in the patients who underwent EAT was measured to be 4.19 times lower than in the non-treated group. This suggests that the squamous metaplasia induced by EAT might help reduce the entry of the influenza virus by down-regulating this key protein.
Our findings indicate that EAT, through its zinc content, could serve as a simple and effective method to potentially prevent influenza infection by limiting the virus's ability to enter cells.
References
Bufan B, Arsenović-Ranin N, Živković I, Ćuruvija I, Blagojević V, et al. Modulation of T-Cell-Dependent Humoral Immune Response to Influenza Vaccine by Multiple Antioxidant/Immunomodulatory Micronutrient Supplementation. Vaccines (Basel). 2024;12. doi:10.3390/vaccines12070743
Nishi K, Yoshimoto S, Nishi S, Nishi T, Nishi R, et al. Epipharyngeal Abrasive Therapy Down-regulates the Expression of Cav1.2: A Key Molecule in Influenza Virus Entry. In Vivo. 2022;36:2357. doi:10.21873/invivo.12967