Overview

SCIENTIFIC SCORE
Moderately Effective
Based on 2 Researches
8.5
USERS' SCORE
Good
Based on 14 Reviews
8.3
Supplement Facts
Serving Size: 1 Vegetarian Capsule
Amount Per Serving
%DV
Zinc (as OptiZinc® zinc monomethionine, zinc citrate)
50 mg
455%

Top Medical Research Studies

8
Zinc may prevent influenza entry
We investigated how zinc, delivered through epipharyngeal abrasive therapy (EAT), might impact the expression of a key molecule known as Cav1.2, which plays a crucial role in allowing the influenza A virus to enter cells. The study included two groups of patients: one group that received EAT, which involved scratching the epipharyngeal mucosa with a zinc chloride-treated swab, and another group that did not receive this treatment.

By analyzing tissue samples, we observed that the levels of Cav1.2 were significantly lower in the EAT-treated patients compared to those who were not treated. In fact, the expression of Cav1.2 in the patients who underwent EAT was measured to be 4.19 times lower than in the non-treated group. This suggests that the squamous metaplasia induced by EAT might help reduce the entry of the influenza virus by down-regulating this key protein.

Our findings indicate that EAT, through its zinc content, could serve as a simple and effective method to potentially prevent influenza infection by limiting the virus's ability to enter cells.
Read More
We examined how combining zinc with other essential micronutrients could impact the immune response to an influenza vaccine. Our study found that this combination, including vitamins C and D, selenium, manganese, and N-acetyl cysteine, led to increased levels of protective antibodies after vaccinations in mice.

Notably, the supplementation improved not just the overall antibody response but also boosted specific immune responses vital for effective virus clearance. We observed a rise in specific types of immune cells, such as germinal center B cells and helper T cells, which are crucial in fighting off infections. Moreover, this combination influenced a greater differentiation of T helper cells, enhancing the production of important cytokines.

While our findings highlighted the beneficial effects of this micronutrient combination on immunity, it is also important to note that the study evaluated these effects in a controlled setting involving multiple micronutrients. Although zinc is included, its isolated impact on the immune response to influenza was less discernible due to the mixture of supplements tested. Overall, our research lays the groundwork for future studies aimed at improving vaccination responses through dietary adjustments.
Read More

Most Useful Reviews

9
Prevention recommendation
4 people found this helpful
The leader in the prevention and treatment of influenza and ARVI! Zinc, paired with vitamin D, is essential for cold prevention. My family takes zinc twice a year for two months as a prophylactic measure. This product is effective; the brand is commendable. I wholeheartedly recommend it.
Read More
9
Well tolerated
It is well tolerated with no side effects, even though zinc can sometimes cause gastrointestinal issues. I take it during influenza season to support my immunity in autumn and spring. Since I started this, I haven't fallen ill. I highly recommend it.
Read More
9
Immunity support
Zinc is a crucial mineral not naturally produced by our bodies, so we must obtain it through diet or supplements. It enhances the immune system and has a direct antiviral effect. Zinc is included in treatment regimens for various viral infections like ARVI, influenza, and others. I take half a capsule daily for a month and highly recommend this product!
Read More

Medical Researches

SCIENTIFIC SCORE
Moderately Effective
Based on 2 Researches
8.5
  • All Researches
We examined how combining zinc with other essential micronutrients could impact the immune response to an influenza vaccine. Our study found that this combination, including vitamins C and D, selenium, manganese, and N-acetyl cysteine, led to increased levels of protective antibodies after vaccinations in mice.

Notably, the supplementation improved not just the overall antibody response but also boosted specific immune responses vital for effective virus clearance. We observed a rise in specific types of immune cells, such as germinal center B cells and helper T cells, which are crucial in fighting off infections. Moreover, this combination influenced a greater differentiation of T helper cells, enhancing the production of important cytokines.

While our findings highlighted the beneficial effects of this micronutrient combination on immunity, it is also important to note that the study evaluated these effects in a controlled setting involving multiple micronutrients. Although zinc is included, its isolated impact on the immune response to influenza was less discernible due to the mixture of supplements tested. Overall, our research lays the groundwork for future studies aimed at improving vaccination responses through dietary adjustments.
Read More
8
Zinc may prevent influenza entry
We investigated how zinc, delivered through epipharyngeal abrasive therapy (EAT), might impact the expression of a key molecule known as Cav1.2, which plays a crucial role in allowing the influenza A virus to enter cells. The study included two groups of patients: one group that received EAT, which involved scratching the epipharyngeal mucosa with a zinc chloride-treated swab, and another group that did not receive this treatment.

By analyzing tissue samples, we observed that the levels of Cav1.2 were significantly lower in the EAT-treated patients compared to those who were not treated. In fact, the expression of Cav1.2 in the patients who underwent EAT was measured to be 4.19 times lower than in the non-treated group. This suggests that the squamous metaplasia induced by EAT might help reduce the entry of the influenza virus by down-regulating this key protein.

Our findings indicate that EAT, through its zinc content, could serve as a simple and effective method to potentially prevent influenza infection by limiting the virus's ability to enter cells.
Read More

User Reviews

USERS' SCORE
Good
Based on 14 Reviews
8.3
  • All Reviews
  • Positive Reviews
  • Negative Reviews
9
Prevention recommendation
4 people found this helpful
The leader in the prevention and treatment of influenza and ARVI! Zinc, paired with vitamin D, is essential for cold prevention. My family takes zinc twice a year for two months as a prophylactic measure. This product is effective; the brand is commendable. I wholeheartedly recommend it.
Read More
9
Well tolerated
It is well tolerated with no side effects, even though zinc can sometimes cause gastrointestinal issues. I take it during influenza season to support my immunity in autumn and spring. Since I started this, I haven't fallen ill. I highly recommend it.
Read More
9
Immunity support
Zinc is a crucial mineral not naturally produced by our bodies, so we must obtain it through diet or supplements. It enhances the immune system and has a direct antiviral effect. Zinc is included in treatment regimens for various viral infections like ARVI, influenza, and others. I take half a capsule daily for a month and highly recommend this product!
Read More
9
Highly recommended for influenza
The zinc dosage is effective at 50 mg for prophylaxis, but for treating influenza, two capsules daily are perfect! The citrate and zinc monomethionine forms offer great bioavailability, especially during influenza and the SARS season. A must-have for any medicine cabinet. I highly recommend it!
Read More
9
Rapid relief from influenza
We always keep this effective zinc in the house at a large dosage of 50 mg to combat ARVI at the first signs. Along with zinc, we take large doses of vitamin D (up to 20,000 IU) and C (500 mg every hour or two). Influenza symptoms diminish significantly within 1-2 days.
Read More

Frequently Asked Questions

9
Rapid relief from influenza
We always keep this effective zinc in the house at a large dosage of 50 mg to combat ARVI at the first signs. Along with zinc, we take large doses of vitamin D (up to 20,000 IU) and C (500 mg every hour or two). Influenza symptoms diminish significantly within 1-2 days.
9
Immunity support
Zinc is a crucial mineral not naturally produced by our bodies, so we must obtain it through diet or supplements. It enhances the immune system and has a direct antiviral effect. Zinc is included in treatment regimens for various viral infections like ARVI, influenza, and others. I take half a capsule daily for a month and highly recommend this product!
9
Highly recommended for influenza
The zinc dosage is effective at 50 mg for prophylaxis, but for treating influenza, two capsules daily are perfect! The citrate and zinc monomethionine forms offer great bioavailability, especially during influenza and the SARS season. A must-have for any medicine cabinet. I highly recommend it!
9
Well tolerated
It is well tolerated with no side effects, even though zinc can sometimes cause gastrointestinal issues. I take it during influenza season to support my immunity in autumn and spring. Since I started this, I haven't fallen ill. I highly recommend it.
9
Prevention recommendation
4 people found this helpful
The leader in the prevention and treatment of influenza and ARVI! Zinc, paired with vitamin D, is essential for cold prevention. My family takes zinc twice a year for two months as a prophylactic measure. This product is effective; the brand is commendable. I wholeheartedly recommend it.
9
Good for prevention
The dosage is excellent for both prevention and treatment during the influenza season!
We examined how combining zinc with other essential micronutrients could impact the immune response to an influenza vaccine. Our study found that this combination, including vitamins C and D, selenium, manganese, and N-acetyl cysteine, led to increased levels of protective antibodies after vaccinations in mice.

Notably, the supplementation improved not just the overall antibody response but also boosted specific immune responses vital for effective virus clearance. We observed a rise in specific types of immune cells, such as germinal center B cells and helper T cells, which are crucial in fighting off infections. Moreover, this combination influenced a greater differentiation of T helper cells, enhancing the production of important cytokines.

While our findings highlighted the beneficial effects of this micronutrient combination on immunity, it is also important to note that the study evaluated these effects in a controlled setting involving multiple micronutrients. Although zinc is included, its isolated impact on the immune response to influenza was less discernible due to the mixture of supplements tested. Overall, our research lays the groundwork for future studies aimed at improving vaccination responses through dietary adjustments.
8
Zinc may prevent influenza entry
We investigated how zinc, delivered through epipharyngeal abrasive therapy (EAT), might impact the expression of a key molecule known as Cav1.2, which plays a crucial role in allowing the influenza A virus to enter cells. The study included two groups of patients: one group that received EAT, which involved scratching the epipharyngeal mucosa with a zinc chloride-treated swab, and another group that did not receive this treatment.

By analyzing tissue samples, we observed that the levels of Cav1.2 were significantly lower in the EAT-treated patients compared to those who were not treated. In fact, the expression of Cav1.2 in the patients who underwent EAT was measured to be 4.19 times lower than in the non-treated group. This suggests that the squamous metaplasia induced by EAT might help reduce the entry of the influenza virus by down-regulating this key protein.

Our findings indicate that EAT, through its zinc content, could serve as a simple and effective method to potentially prevent influenza infection by limiting the virus's ability to enter cells.

References

  1. Bufan B, Arsenović-Ranin N, Živković I, Ćuruvija I, Blagojević V, et al. Modulation of T-Cell-Dependent Humoral Immune Response to Influenza Vaccine by Multiple Antioxidant/Immunomodulatory Micronutrient Supplementation. Vaccines (Basel). 2024;12. doi:10.3390/vaccines12070743
  2. Nishi K, Yoshimoto S, Nishi S, Nishi T, Nishi R, et al. Epipharyngeal Abrasive Therapy Down-regulates the Expression of Cav1.2: A Key Molecule in Influenza Virus Entry. In Vivo. 2022;36:2357. doi:10.21873/invivo.12967
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