For a long time, close to 5 years I was taking these LE DHEA dissolving tablets along with high levels of vitamin D. During that time I did not get any colds or Influenza infections. i also had increased energy and experienced increased strength in my workouts at the gym. But since it takes some degree of dedication to consistently take the dissolving tablets each day, I eventually stopped taking them. After a couple of years I started getting colds again and eventually contracted a multi drug resistant e coli infection which failed to respond to a series of three different antibiotics. My energy level and physical strength were also suffering. At that point in desperation I started taking large amounts of this LE DHEA product, 250mg per day, and the drug resistant infection has gradually gone away and at this point no symptoms remain, and my strength and energy level is back to where it was before. At this point I have reduced the amount of DHEA I am taking, but am really thankful for the way my body has responded to it. I am certainly not going to stop taking it again