We explored the effects of vitamin C on natural killer (NK) cell activity in patients with coronary artery disease (CAD). Our research involved isolating NK cells from 29 CAD patients and treating them with various stimulatory factors, including ascorbic acid—better known as vitamin C.
What we found was quite interesting: when NK cells were treated with ascorbic acid, there was a significant increase in their ability to proliferate. This meant that the NK cells were more active and potentially more effective in responding to threats in the body, which is vital for those dealing with heart conditions.
Furthermore, we measured serum lactate dehydrogenase (LDH) levels, discovering a negative correlation between LDH and NK cell activity. Higher LDH levels seemed to indicate lower proliferation capability in NK cells influenced by interleukins.
Overall, our study suggests that vitamin C could play a positive role in enhancing immune function in CAD patients by promoting NK cell proliferation. However, it's important to note that while vitamin C shows promise, further research is needed to fully understand its impact on cardiovascular health and immune regulation.
Read More
8
Vitamin C may help prevent stroke
Causal Effect of Macronutrient and Micronutrient Intake on Stroke: A Two-Sample Mendelian Randomization Study.
We investigated the potential protective effects of vitamin C on stroke risk, drawing on data from a robust two-sample Mendelian randomization study. This research compared genetic predictors of nutrient intake to stroke outcomes, focusing particularly on the intake of various vitamins, including vitamin C.
Our findings revealed that higher levels of vitamin C are linked to a reduced risk of cardioembolic stroke, with a noteworthy odds ratio suggesting that this vitamin could play a significant protective role. Specifically, when we looked at the statistics, the odds ratio was 0.759, indicating a promising association with stroke prevention. This evidence positions vitamin C as a potential target for public health strategies aimed at reducing stroke incidence.
However, while the results regarding vitamin C are encouraging, we must approach them with caution. The overall design of the study limits our conclusions, suggesting that while vitamin C appears beneficial, further research is necessary to fully understand its effects on cardiovascular health.
Read More
9
Vitamin C may lower blood pressure
Effect of vitamin C and hawthorn beverage formula on blood pressure and oxidative stress in heat-exposed workers: a cluster-randomized controlled trial.
We conducted a study to evaluate the effects of a vitamin C supplement combined with a hawthorn beverage on blood pressure and oxidative stress among workers exposed to heat. This involved a 40-day cluster-randomized controlled trial where participants were split into two groups: one received the vitamin C and hawthorn drink, while the other was provided with slightly salted water.
Throughout the study, we measured blood pressure and levels of a specific oxidative stress marker at different intervals. Notably, we observed significant reductions in both systolic and diastolic blood pressure among those who consumed the vitamin C and hawthorn beverage compared to the control group. This suggests that the combination may help manage elevated blood pressure linked to heat exposure.
The findings highlight the potential role of vitamin C, especially when paired with other beneficial compounds in the hawthorn beverage, in combating oxidative stress and promoting cardiovascular health in individuals working in challenging environmental conditions.
Read More
Most Useful Reviews
9
Essential for health
2 people found this helpful
This vitamin C supplement strengthens the immune system and supports cardiovascular health. It also promotes tissue repair and counteracts flu-like symptoms from deficiency. The dosage of 1000 mg is perfect for maintenance, and it's easy on the stomach, making it essential for my cardiovascular disease management.
Read More
9
Effective supplement
1 people found this helpful
Good vitamin C with biocaercetin, this supplement is not a classic vitamin C. It's fortified with quercetin, beneficial for blood circulation and cardiovascular disease. Quercetin helps with the immune system, especially during seasonal colds, and the combination with vitamin C aids iron absorption and collagen production. I find the Life Extension Vitamin C with bioquercetin phytosomes an effective choice. I recommend purchasing it!
Read More
7.5
Powerful antioxidants
1 people found this helpful
Vitamin C and quercetin are potent antioxidants in this supplement. They fight free radicals and may help with cardiovascular disease while boosting my immune system. I’ve had great results with it in addressing my health concerns. I appreciate its positive impact on my overall well-being.
Effect of vitamin C and hawthorn beverage formula on blood pressure and oxidative stress in heat-exposed workers: a cluster-randomized controlled trial.
We conducted a study to evaluate the effects of a vitamin C supplement combined with a hawthorn beverage on blood pressure and oxidative stress among workers exposed to heat. This involved a 40-day cluster-randomized controlled trial where participants were split into two groups: one received the vitamin C and hawthorn drink, while the other was provided with slightly salted water.
Throughout the study, we measured blood pressure and levels of a specific oxidative stress marker at different intervals. Notably, we observed significant reductions in both systolic and diastolic blood pressure among those who consumed the vitamin C and hawthorn beverage compared to the control group. This suggests that the combination may help manage elevated blood pressure linked to heat exposure.
The findings highlight the potential role of vitamin C, especially when paired with other beneficial compounds in the hawthorn beverage, in combating oxidative stress and promoting cardiovascular health in individuals working in challenging environmental conditions.
Read More
8
Antioxidants show promise for FGR
The Use of Antioxidants for Cardiovascular Protection in Fetal Growth Restriction: A Systematic Review.
This systematic review focused on the potential effects of antioxidants, particularly vitamin C, on cardiovascular health in cases of fetal growth restriction (FGR). We assessed various studies that examined how these treatments might enhance cardiac and vascular outcomes in affected individuals.
Our exploration revealed that a majority of the studies indicated some level of cardiovascular protection following antioxidant intervention. Specifically, 71% of the studies noted improvements in at least one of the cardiac or vascular parameters in growth-restricted offspring. Vitamin C, along with other antioxidants, was highlighted as part of several approaches to reduce oxidative stress, which is known to contribute to cardiovascular issues.
However, it's essential to note that the specific impact of vitamin C alone was not extensively distinguished from its combined effects with other antioxidants. This ambiguity makes it challenging to pin down its isolated benefits.
Overall, while antioxidant treatments present a promising avenue for addressing cardiovascular deficits associated with FGR, crucial gaps in research remain, preventing us from determining the most effective strategies for clinical use.
Read More
8
Vitamin C may help prevent stroke
Causal Effect of Macronutrient and Micronutrient Intake on Stroke: A Two-Sample Mendelian Randomization Study.
We investigated the potential protective effects of vitamin C on stroke risk, drawing on data from a robust two-sample Mendelian randomization study. This research compared genetic predictors of nutrient intake to stroke outcomes, focusing particularly on the intake of various vitamins, including vitamin C.
Our findings revealed that higher levels of vitamin C are linked to a reduced risk of cardioembolic stroke, with a noteworthy odds ratio suggesting that this vitamin could play a significant protective role. Specifically, when we looked at the statistics, the odds ratio was 0.759, indicating a promising association with stroke prevention. This evidence positions vitamin C as a potential target for public health strategies aimed at reducing stroke incidence.
However, while the results regarding vitamin C are encouraging, we must approach them with caution. The overall design of the study limits our conclusions, suggesting that while vitamin C appears beneficial, further research is necessary to fully understand its effects on cardiovascular health.
Read More
7
Vitamin C enhances NK cell proliferation
Proliferation capability of natural killer cells upon cytokines stimulation correlated negatively with serum lactate dehydrogenase level in coronary artery disease patients.
We explored the effects of vitamin C on natural killer (NK) cell activity in patients with coronary artery disease (CAD). Our research involved isolating NK cells from 29 CAD patients and treating them with various stimulatory factors, including ascorbic acid—better known as vitamin C.
What we found was quite interesting: when NK cells were treated with ascorbic acid, there was a significant increase in their ability to proliferate. This meant that the NK cells were more active and potentially more effective in responding to threats in the body, which is vital for those dealing with heart conditions.
Furthermore, we measured serum lactate dehydrogenase (LDH) levels, discovering a negative correlation between LDH and NK cell activity. Higher LDH levels seemed to indicate lower proliferation capability in NK cells influenced by interleukins.
Overall, our study suggests that vitamin C could play a positive role in enhancing immune function in CAD patients by promoting NK cell proliferation. However, it's important to note that while vitamin C shows promise, further research is needed to fully understand its impact on cardiovascular health and immune regulation.
Read More
User Reviews
USERS' SCORE
Moderately Good
Based on 17 Reviews
7.9
All Reviews
Positive Reviews
Negative Reviews
9
Essential for health
2 people found this helpful
This vitamin C supplement strengthens the immune system and supports cardiovascular health. It also promotes tissue repair and counteracts flu-like symptoms from deficiency. The dosage of 1000 mg is perfect for maintenance, and it's easy on the stomach, making it essential for my cardiovascular disease management.
Read More
9
Effective supplement
1 people found this helpful
Good vitamin C with biocaercetin, this supplement is not a classic vitamin C. It's fortified with quercetin, beneficial for blood circulation and cardiovascular disease. Quercetin helps with the immune system, especially during seasonal colds, and the combination with vitamin C aids iron absorption and collagen production. I find the Life Extension Vitamin C with bioquercetin phytosomes an effective choice. I recommend purchasing it!
Read More
7.5
Powerful antioxidants
1 people found this helpful
Vitamin C and quercetin are potent antioxidants in this supplement. They fight free radicals and may help with cardiovascular disease while boosting my immune system. I’ve had great results with it in addressing my health concerns. I appreciate its positive impact on my overall well-being.
Read More
9
Useful composition
This supplement combines vitamin C and quercetin, promoting good blood circulation and immunity, particularly during seasonal colds. I found the composition beneficial and the reviews supportive of its effects.
Read More
7.5
Effective supplement
82 people found this helpful
Excellent formulation! This vitamin C supplement with quercetin helps combat viruses affecting the upper respiratory tract. I use it when I feel unwell, and it prevents colds. If I do catch a virus, my symptoms are mild. The price is reasonable, and I feel reassured knowing it aids my health and may support my cardiovascular disease risk.
Cardiovascular disease (CVD) is a broad term that encompasses a range of heart and blood vessel disorders. This can include conditions such as coronary artery disease, which leads to heart attacks; cerebrovascular disease that results in strokes; and peripheral artery disease affecting blood flow to the limbs. The key risk factors for CVD often include high blood pressure, high cholesterol, obesity, smoking, a sedentary lifestyle, and diabetes. By identifying and managing these risk factors, individuals can significantly reduce their likelihood of developing cardiovascular problems.
Prevention and treatment strategies often involve lifestyle modifications such as adopting a heart-healthy diet rich in fruits, vegetables, whole grains, and lean proteins, alongside engaging in regular physical activity. In some cases, medications might be necessary to control blood pressure or cholesterol levels. Regular check-ups with a healthcare provider are essential for monitoring heart health, especially for individuals with a family history of CVD. Understanding the signs and symptoms of cardiovascular issues—like chest pain, shortness of breath, or fatigue—can help in seeking timely medical attention, ultimately leading to better outcomes.
Vitamin C, also known as ascorbic acid, is a water-soluble vitamin that plays a critical role in numerous bodily functions. As an essential nutrient, it contributes to the growth and repair of tissues in the body, and it is vital for the production of collagen, an important protein that helps maintain skin, cartilage, tendons, ligaments, and blood vessels. Additionally, Vitamin C acts as a powerful antioxidant, which means it helps combat free radicals—unstable molecules that can cause oxidative stress and contribute to various chronic diseases.
Moreover, Vitamin C enhances iron absorption from plant-based foods, making it a vital component for those following vegetarian or vegan diets. While many people get sufficient Vitamin C from a well-balanced diet that includes fruits and vegetables like oranges, strawberries, kiwi, broccoli, and bell peppers, some individuals might require supplementation. It's generally recommended to stay within the daily intake guidelines, as excessive consumption can lead to gastrointestinal disturbances. Overall, Vitamin C is not just a skincare celebrity—it's a fundamental part of maintaining overall health and well-being.
While there is ongoing research into the effects of Vitamin C on cardiovascular health, the evidence remains mixed. Some studies suggest that Vitamin C may help improve endothelial function, lower blood pressure, and reduce oxidized LDL cholesterol, which are all risk factors associated with cardiovascular disease. Antioxidants like Vitamin C can combat oxidative stress, a contributor to various health issues, including heart disease. However, it's essential to note that these potential benefits are often seen when Vitamin C is consumed as part of a balanced diet rich in fruits and vegetables, rather than in supplement form alone.
On the flip side, there are also studies that show no significant long-term benefits of Vitamin C supplementation in preventing heart disease or improving heart health outcomes. The American Heart Association emphasizes that focusing on overall dietary patterns and lifestyle changes—like increased physical activity, maintaining a healthy weight, and a diet high in whole foods—should be prioritized over relying solely on individual supplements. Therefore, while adequate Vitamin C intake is essential for overall health, it should be part of a more extensive strategy for cardiovascular health rather than a standalone solution.
Based on user reviews of vitamin C supplements, individuals typically report experiencing positive effects on cardiovascular health over a period of several weeks to a couple of months. For example, users note improvements in overall well-being and cardiovascular support after consistent use, with recommendations suggesting that the supplement may aid in managing cardiovascular disease alongside immune support (review-id: 9e24a9f6-1a8a-49cd-8198-820eae96d41c, review-id: 90cd55c4-d6a2-43b0-8940-bdf49cad7b0c). One reviewer indicated significant benefits that contributed to their health concerns, which highlights the gradual improvement reported by many users.
However, the timeline for noticeable results can vary depending on individual health conditions and the specific formulation of the supplement. A number of reviews emphasize the importance of consistency and the role of complementary ingredients, like quercetin, which may enhance the cardiovascular benefits of vitamin C (review-id: c0b837c3-4791-4f9e-98bc-b726a627f96b). Ultimately, while some users might note initial benefits in a few weeks, others may require longer usage to experience substantial health improvements related to cardiovascular disease management.
This vitamin C supplement shows promise for supporting cardiovascular health, particularly in certain contexts. A systematic review indicates that antioxidants, including vitamin C, have been associated with improved cardiac and vascular outcomes in individuals with fetal growth restriction, with 71% of studies noting some cardiovascular benefits following antioxidant treatments [1]. Furthermore, research indicates that vitamin C can enhance the activity of natural killer cells in patients with coronary artery disease, potentially bolstering immune responses critical in heart-related conditions [2].
Additionally, a two-sample Mendelian randomization study found that increased vitamin C levels are linked to a reduced risk of cardioembolic stroke, suggesting its potential as a preventive measure for stroke [3]. A study involving heat-exposed workers also demonstrated that a vitamin C and hawthorn combination could significantly lower blood pressure readings, implying its benefits for managing cardiovascular stress [4]. Collectively, while the evidence leans towards a beneficial role of vitamin C in cardiovascular health, further research is essential to fully understand its effects and establish definitive clinical guidelines.
Users report various improvements in symptoms related to immune support and cardiovascular health after using vitamin C supplements, particularly those enhanced with quercetin. Many individuals have noted that their overall well-being has improved, with specific mentions of enhanced immune function during cold seasons and reduced illness severity. For instance, one reviewer stated that increased dosages at the onset of illness helped them cope effectively with respiratory viruses, resulting in milder symptoms (review-id: 413f66de-02f2-4baa-95f4-5a68ae15b0de). Additionally, others have experienced positive effects on cardiovascular health, including improvements in blood circulation and support against cardiovascular diseases (review-id: c0b837c3-4791-4f9e-98bc-b726a627f96b).
Users highly appreciate the synergistic effect of vitamin C and quercetin, noting that it provides powerful antioxidant support and enhances recovery from illnesses. Several reviews highlight feelings of increased energy and overall vitality, which many attribute to the supplement's role in reducing oxidative stress and inflammation (review-id: ad023bdc-c406-4100-8a8f-c66fce06832b). While individual results can vary, the collective feedback suggests a favorable impact on both immune and cardiovascular health, emphasizing the importance of consistent use for optimal effects.
Users report a positive experience when combining vitamin C with quercetin for managing cardiovascular disease. Many mention that this specific formulation not only strengthens the immune system but also enhances blood circulation, which is essential for cardiovascular health. Quercetin is highlighted for its role in reducing inflammation and supporting vascular function, making it a beneficial addition to those already concerned about cardiovascular issues. Several reviewers noted improvements in their overall health and attributed these benefits to the complementary effects of vitamin C and quercetin, particularly during seasonal illnesses (review-id: 90cd55c4-d6a2-43b0-8940-bdf49cad7b0c, review-id: c0b837c3-4791-4f9e-98bc-b726a627f96b).
Additionally, some users experimented with combining this vitamin C supplement with other nutrients, such as zinc and elderberry, to improve their immune response during illness, which in turn supported their cardiovascular health (review-id: a2b02f24-3de1-4a36-bba5-efba862e82a2). This synergistic effect is a recurring theme in user reviews, with many recommending these combinations for optimal health benefits. Overall, the consensus is that the joint action of vitamin C and quercetin is particularly effective in promoting cardiovascular support while also addressing immune needs, underscoring its value as part of a holistic health regimen (review-id: 413f66de-02f2-4baa-95f4-5a68ae15b0de).
Based on user reviews, there seems to be some agreement on the dosage of Vitamin C for supporting cardiovascular health. Many users report that a daily intake of around 1000 mg is effective for maintenance and management of cardiovascular disease. For example, one user stated that a dose of 1000 mg is "perfect for maintenance" and is "essential for my cardiovascular disease management" Read Review. Other users mentioned that they sometimes increase their dosage when feeling unwell or require additional immune support, indicating that flexibility in dosage may also play a role in treatment Read Review.
Moreover, some participants expressed their preference for supplements combining Vitamin C with additional ingredients, such as quercetin, which they believe boost cardiovascular health and aid prevention strategies against disease Read Review. A user noted that while the dosage may be high for prevention, splitting it makes it manageable Read Review. Therefore, while the consensus seems to lean towards 1000 mg as an appropriate dose, adjustments based on individual health needs and product formulations are also commonly discussed among users.
9
Essential for health
2 people found this helpful
This vitamin C supplement strengthens the immune system and supports cardiovascular health. It also promotes tissue repair and counteracts flu-like symptoms from deficiency. The dosage of 1000 mg is perfect for maintenance, and it's easy on the stomach, making it essential for my cardiovascular disease management.
7.5
Antiviral properties
4 people found this helpful
This supplement is fantastic for immunity, especially against COVID-19. Quercetin aids in reducing the risk of cardiovascular diseases while also providing antiviral effects. I take it daily and, if needed, increase the dosage. My experience has been positive, and it really supports my health.
9
Effective supplement
1 people found this helpful
Good vitamin C with biocaercetin, this supplement is not a classic vitamin C. It's fortified with quercetin, beneficial for blood circulation and cardiovascular disease. Quercetin helps with the immune system, especially during seasonal colds, and the combination with vitamin C aids iron absorption and collagen production. I find the Life Extension Vitamin C with bioquercetin phytosomes an effective choice. I recommend purchasing it!
7.5
Great antioxidant formula
14 people found this helpful
A powerful antioxidant featuring vitamin C and bio-quercetin, which reduces inflammation and strengthens the immune system. I find the dosage too high for prevention, so I split it. Despite minor inconveniences, it’s effective, beneficial for my health, and also supports cardiovascular disease reduction. I recommend it for anyone.
8
Antioxidants show promise for FGR
The Use of Antioxidants for Cardiovascular Protection in Fetal Growth Restriction: A Systematic Review.
This systematic review focused on the potential effects of antioxidants, particularly vitamin C, on cardiovascular health in cases of fetal growth restriction (FGR). We assessed various studies that examined how these treatments might enhance cardiac and vascular outcomes in affected individuals.
Our exploration revealed that a majority of the studies indicated some level of cardiovascular protection following antioxidant intervention. Specifically, 71% of the studies noted improvements in at least one of the cardiac or vascular parameters in growth-restricted offspring. Vitamin C, along with other antioxidants, was highlighted as part of several approaches to reduce oxidative stress, which is known to contribute to cardiovascular issues.
However, it's essential to note that the specific impact of vitamin C alone was not extensively distinguished from its combined effects with other antioxidants. This ambiguity makes it challenging to pin down its isolated benefits.
Overall, while antioxidant treatments present a promising avenue for addressing cardiovascular deficits associated with FGR, crucial gaps in research remain, preventing us from determining the most effective strategies for clinical use.
7
Vitamin C enhances NK cell proliferation
Proliferation capability of natural killer cells upon cytokines stimulation correlated negatively with serum lactate dehydrogenase level in coronary artery disease patients.
We explored the effects of vitamin C on natural killer (NK) cell activity in patients with coronary artery disease (CAD). Our research involved isolating NK cells from 29 CAD patients and treating them with various stimulatory factors, including ascorbic acid—better known as vitamin C.
What we found was quite interesting: when NK cells were treated with ascorbic acid, there was a significant increase in their ability to proliferate. This meant that the NK cells were more active and potentially more effective in responding to threats in the body, which is vital for those dealing with heart conditions.
Furthermore, we measured serum lactate dehydrogenase (LDH) levels, discovering a negative correlation between LDH and NK cell activity. Higher LDH levels seemed to indicate lower proliferation capability in NK cells influenced by interleukins.
Overall, our study suggests that vitamin C could play a positive role in enhancing immune function in CAD patients by promoting NK cell proliferation. However, it's important to note that while vitamin C shows promise, further research is needed to fully understand its impact on cardiovascular health and immune regulation.
8
Vitamin C may help prevent stroke
Causal Effect of Macronutrient and Micronutrient Intake on Stroke: A Two-Sample Mendelian Randomization Study.
We investigated the potential protective effects of vitamin C on stroke risk, drawing on data from a robust two-sample Mendelian randomization study. This research compared genetic predictors of nutrient intake to stroke outcomes, focusing particularly on the intake of various vitamins, including vitamin C.
Our findings revealed that higher levels of vitamin C are linked to a reduced risk of cardioembolic stroke, with a noteworthy odds ratio suggesting that this vitamin could play a significant protective role. Specifically, when we looked at the statistics, the odds ratio was 0.759, indicating a promising association with stroke prevention. This evidence positions vitamin C as a potential target for public health strategies aimed at reducing stroke incidence.
However, while the results regarding vitamin C are encouraging, we must approach them with caution. The overall design of the study limits our conclusions, suggesting that while vitamin C appears beneficial, further research is necessary to fully understand its effects on cardiovascular health.
9
Vitamin C may lower blood pressure
Effect of vitamin C and hawthorn beverage formula on blood pressure and oxidative stress in heat-exposed workers: a cluster-randomized controlled trial.
We conducted a study to evaluate the effects of a vitamin C supplement combined with a hawthorn beverage on blood pressure and oxidative stress among workers exposed to heat. This involved a 40-day cluster-randomized controlled trial where participants were split into two groups: one received the vitamin C and hawthorn drink, while the other was provided with slightly salted water.
Throughout the study, we measured blood pressure and levels of a specific oxidative stress marker at different intervals. Notably, we observed significant reductions in both systolic and diastolic blood pressure among those who consumed the vitamin C and hawthorn beverage compared to the control group. This suggests that the combination may help manage elevated blood pressure linked to heat exposure.
The findings highlight the potential role of vitamin C, especially when paired with other beneficial compounds in the hawthorn beverage, in combating oxidative stress and promoting cardiovascular health in individuals working in challenging environmental conditions.
References
Rock CR, Miller SL, Allison BJ. The Use of Antioxidants for Cardiovascular Protection in Fetal Growth Restriction: A Systematic Review. Antioxidants (Basel). 2024;13. doi:10.3390/antiox13111400
Guo X, Xiao T, Lin L, Gao Q, Lai B, et al. Proliferation capability of natural killer cells upon cytokines stimulation correlated negatively with serum lactate dehydrogenase level in coronary artery disease patients. Front Immunol. 2024;15:1436747. doi:10.3389/fimmu.2024.1436747
Dong G, Xu W, Xu L. Causal Effect of Macronutrient and Micronutrient Intake on Stroke: A Two-Sample Mendelian Randomization Study. Nutrients. 2024;16. doi:10.3390/nu16172818
Du W, Zhang S, Yang J, Fan H. Effect of vitamin C and hawthorn beverage formula on blood pressure and oxidative stress in heat-exposed workers: a cluster-randomized controlled trial. Asia Pac J Clin Nutr. 2024;33:503. doi:10.6133/apjcn.202412_33(4).0005