Last update
5/28/2026
Research Authors

Overview

SCIENTIFIC SCORE
Moderately Effective
Based on 1 Research
8
USERS' SCORE
Good
Based on 12 Reviews
8.8
Supplement Facts
Serving Size:  1 Vegetarian Tablet
Amount Per Serving
%DV
Vitamin C (as ascorbic acid)
1000 mg
1111%
Bio-Quercetin® Proprietary Blend[providing 35% quercetin (5 mg) [from Japanese sophora concentrate (flower bud)],30% galactomannans (4 mg) [from fenugreek (seed)]
15 mg
**
📅 Last updated:

Top Medical Research Studies

8
Vitamin C reduces heartburn symptoms
We investigated how vitamin C, specifically in the form of a 2% vitamin C solution spray, could help alleviate heartburn symptoms following Lugol chromoendoscopy, a procedure that involves staining the esophagus to better visualize abnormalities. In a well-structured study with 240 participants, we used a randomized, double-blind approach to compare the effectiveness of vitamin C to normal saline and sodium thiosulfate solutions.

Our results showed that vitamin C spray significantly reduced both acute heartburn symptoms and late discomfort when compared to the saline solution. Specifically, 33% of participants using vitamin C reported relief from acid regurgitation or heartburn, compared to just 15% with sodium thiosulfate. Additionally, patients noted an improvement in retrosternal pain, with 21% finding relief from the vitamin C treatment versus 9% from sodium thiosulfate.

Furthermore, vitamin C offered a quicker discoloration of the iodine-stained mucosa compared to saline, enhancing the overall experience of the procedure. These findings suggest that incorporating vitamin C spray into post-procedural care could be a helpful strategy for patients facing discomfort after undergoing Lugol chromoendoscopy.
Read More

Most Useful Reviews

9
No heartburn
1 people found this helpful
I take half a tablet in the morning and evening! It's sour but there’s no heartburn!
Read More
10
Works great
Excellent! I enjoyed this vitamin C, having chosen it out of curiosity. There are no side effects, no heartburn either. When I'm unwell, I take a higher dose, and it works wonderfully!
Read More
9
Immune system boost
My favourite vitamin C capsules from Life Extension don’t cause any heartburn and effectively strengthen my immune system, with very good results.
Read More

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Medical Researches

SCIENTIFIC SCORE
Moderately Effective
Based on 1 Research
8
  • All Researches
8
Vitamin C reduces heartburn symptoms
We investigated how vitamin C, specifically in the form of a 2% vitamin C solution spray, could help alleviate heartburn symptoms following Lugol chromoendoscopy, a procedure that involves staining the esophagus to better visualize abnormalities. In a well-structured study with 240 participants, we used a randomized, double-blind approach to compare the effectiveness of vitamin C to normal saline and sodium thiosulfate solutions.

Our results showed that vitamin C spray significantly reduced both acute heartburn symptoms and late discomfort when compared to the saline solution. Specifically, 33% of participants using vitamin C reported relief from acid regurgitation or heartburn, compared to just 15% with sodium thiosulfate. Additionally, patients noted an improvement in retrosternal pain, with 21% finding relief from the vitamin C treatment versus 9% from sodium thiosulfate.

Furthermore, vitamin C offered a quicker discoloration of the iodine-stained mucosa compared to saline, enhancing the overall experience of the procedure. These findings suggest that incorporating vitamin C spray into post-procedural care could be a helpful strategy for patients facing discomfort after undergoing Lugol chromoendoscopy.
Read More

User Reviews

USERS' SCORE
Good
Based on 12 Reviews
8.8
  • All Reviews
  • Positive Reviews
  • Negative Reviews
9
No heartburn
1 people found this helpful
I take half a tablet in the morning and evening! It's sour but there’s no heartburn!
Read More
10
Works great
Excellent! I enjoyed this vitamin C, having chosen it out of curiosity. There are no side effects, no heartburn either. When I'm unwell, I take a higher dose, and it works wonderfully!
Read More
9
Immune system boost
My favourite vitamin C capsules from Life Extension don’t cause any heartburn and effectively strengthen my immune system, with very good results.
Read More
9
No heartburn
I really liked this vitamin. It swallows well and there’s no heartburn. I also take zinc, and the bioquercetin phytosomes help zinc penetrate cells quickly.
Read More
9
No side effects
I drink these vitamins in the winter without any heartburn, and the results are excellent—I noticed no side effects!
Read More

Frequently Asked Questions

9
No heartburn
1 people found this helpful
I take half a tablet in the morning and evening! It's sour but there’s no heartburn!
9
Good quality
The quality is good. This vitamin C doesn’t cause any heartburn.
9
No heartburn
I really liked this vitamin. It swallows well and there’s no heartburn. I also take zinc, and the bioquercetin phytosomes help zinc penetrate cells quickly.
10
Works great
Excellent! I enjoyed this vitamin C, having chosen it out of curiosity. There are no side effects, no heartburn either. When I'm unwell, I take a higher dose, and it works wonderfully!
9
Immune system boost
My favourite vitamin C capsules from Life Extension don’t cause any heartburn and effectively strengthen my immune system, with very good results.
9
Reliable brand
I take these vitamins every morning. They're great since there’s no heartburn, and I trust the manufacturer.
8
Vitamin C reduces heartburn symptoms
We investigated how vitamin C, specifically in the form of a 2% vitamin C solution spray, could help alleviate heartburn symptoms following Lugol chromoendoscopy, a procedure that involves staining the esophagus to better visualize abnormalities. In a well-structured study with 240 participants, we used a randomized, double-blind approach to compare the effectiveness of vitamin C to normal saline and sodium thiosulfate solutions.

Our results showed that vitamin C spray significantly reduced both acute heartburn symptoms and late discomfort when compared to the saline solution. Specifically, 33% of participants using vitamin C reported relief from acid regurgitation or heartburn, compared to just 15% with sodium thiosulfate. Additionally, patients noted an improvement in retrosternal pain, with 21% finding relief from the vitamin C treatment versus 9% from sodium thiosulfate.

Furthermore, vitamin C offered a quicker discoloration of the iodine-stained mucosa compared to saline, enhancing the overall experience of the procedure. These findings suggest that incorporating vitamin C spray into post-procedural care could be a helpful strategy for patients facing discomfort after undergoing Lugol chromoendoscopy.

References

  1. Jin D, Wang J, Zhan Q, Huang K, Wang H, et al. The safety and efficacy of 2% vitamin C solution spray for relief of mucosal irritation caused by Lugol chromoendoscopy: a multicenter, randomized, double-blind, parallel trial. Gastrointest Endosc. 2020;92:554. 10.1016/j.gie.2019.11.028
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